UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

HUMAN STUDIES REVIEW BOARD (HSRB)

PUBLIC TELECONFERENCE/WEBINAR

 MEETING AGENDA

Wednesday, March 28, 2012

2:00 pm - 4:00 pm (Eastern Time)*

HSRB MEETING FOR REVIEW AND APPROVAL OF THE

DRAFT JANUARY 26, 2012 HSRB MEETING FINAL REPORT

HSRB WEB SITE http://www.epa.gov/osa/hsrb/

Docket Telephone: (202) 566 1752

Docket Number: EPA–HQ–ORD–2012–0175

Meeting location via telephone/Internet only

Dial in number 866-299-3188; conference code 2025647189 

https://epa.connectsolutions.com/hsrbtele

2:00 PM	Convene Meeting and Identification of Board Members – Jim
Downing (Designated Federal Officer, EPA HSRB, OSA)

2:10 PM*	Meeting Administrative Procedures – Jim Downing, DFO

2:15 PM	Meeting Process – Sean Philpott, Ph.D. (HSRB Chair)

2:20 PM	Public Comments

2:30 PM	Board Discussion and Decision on Final Report – Sean Philpott,
Ph.D. (HSRB Chair)

The Board’s response to EPA charge questions presented at the January
26, 2012 meeting.

A new scenario design and associated protocol from the Agricultural
Handler Exposure Task Force (AHETF) describing proposed research to
measure dermal and inhalation exposure to workers who mix, load, and
apply liquid pesticides with powered handgun equipment.

Charge to the Board - Science

Is the research likely to generate scientifically reliable data, useful
for assessing the exposure of workers mixing, loading, and applying
pesticides in managed horticultural facilities using powered handgun
equipment?

Charge to the Board - Ethics: 

Is the research likely to meet the applicable requirements of 40 CFR
part 26, subparts K and L?

A completed scenario monograph and study report from the Antimicrobial
Exposure Assessment Task Force II (AEATF) in which the dermal and
inhalation exposure of professional janitorial workers was monitored as
they applied a liquid antimicrobial pesticide product for indoor surface
disinfecting using a pressurized aerosol can.

Charge to the Board: 

Was the research reported in the Antimicrobial Exposure Assessment Task
Force II (AEATF) completed aerosol study report faithful to the design
and objectives of the protocol and governing documents of AEATF?

Has EPA adequately characterized, from a scientific perspective, the
limitations on these data that should be considered when using the data
in estimating the exposure of professional janitorial workers who apply
liquid antimicrobial pesticide products to indoor surfaces using
pressurized aerosol cans?

Charge to the Board - Ethics:

Does available information support a determination that the study was
conducted in substantial compliance with subparts K and L of 40 CFR Part
26?

A completed Carroll-Loye Biological Research, Inc. (CLBR) study (No Mas
003) to evaluate the field repellent efficacy against mosquitoes of a
product containing 16% para-methane-3,8-diol and 2% lemongrass oil.

Charge to the Board: 

Is the CLBR completed study No Mas 003 sufficiently sound, from a
scientific perspective, to be used to estimate the duration of complete
protection against mosquitoes provided by the tested repellent?

Does available information support a determination that the study No Mas
003 was conducted in substantial compliance with 40 CFR Part 26,
subparts K and L?

3:55 PM*	Summary and Next Steps – Sean Philpott, Ph.D. (HSRB Chair)
and Jim Downing (DFO)

4:00 PM* 	Adjournment

*Note that agenda times are approximate. For further information, please
contact the Designated Federal Officer for this meeting, Jim Downing via
telephone: (202) 564-2468 or email:   HYPERLINK
"mailto:downing.jim@epa.gov"  downing.jim@epa.gov 

