5/27/08 DRAFT

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

HUMAN STUDIES REVIEW BOARD (HSRB)

JUNE 24-25, 2008  

PUBLIC MEETING

Tuesday, June 24, 2008  

Environmental Protection Agency 

Conference Center - Lobby Level 

One Potomac Yard (South Bldg.)

2777 S. Crystal Drive

 Arlington, VA 22202 

HSRB WEB SITE   http://www.epa.gov/osa/hsrb/

Docket Telephone: (202) 566 1752

Docket Number: EPA-HQ-ORD-2008-0355

( 8:30 AM	Convene Meeting and Identification of Board Members – Celia
Fisher, Ph.D. (HSRB Chair)

( 8:40 AM	Welcome – George Gray, Ph.D. (EPA Science Advisor) 

( 8:50 AM	Opening Remarks – Debbie Edwards, Ph.D. (Director, Office of
Pesticide Programs, [OPP], EPA)

( 9:00 AM	Meeting Administrative Procedures - Paul Lewis, Ph.D.
(Designated Federal Officer [DFO], HSRB, OSA, EPA) 

( 9:10 AM	EPA Follow-up on Pesticide Specific HSRB Recommendations – 
Mr. William Jordan (OPP, EPA)

AHETF Pesticide Handler Protocols: Closed-Cab Airblast Scenario

( 9:30 AM	Overview - Mr. William Jordan (OPP, EPA)

( 9:45 AM	Science and Ethics Assessment of AHETF Protocol – Mr.
Jeffrey Evans, (OPP, EPA), Mr. Matthew Crowley (OPP, EPA) and Mr. John
Carley (OPP, EPA)    

( 10:30 AM	Break    

( 10:45 AM	Science and Ethics Assessment of AHETF Protocol (continued)
– Mr. Jeffrey Evans, (OPP, EPA), Mr. Matthew Crowley (OPP, EPA) and
Mr. John Carley (OPP, EPA)    

( 11:30 AM	Public Comments    

( 12:00 PM	Lunch   

( 1:30 PM	Board Discussion    

If AHETF’s proposed closed-cab airblast application scenario design,
field study protocols AHE55 and AHE56, and supporting documentation are
revised as suggested in EPA’s reviews:

Does the research appear likely to generate scientifically reliable
data, useful for assessing the exposure of handlers who apply liquid
pesticides using airblast equipment drawn by vehicles with closed cabs? 

Does the research appear to meet the applicable requirements of 40 CFR
part 26, subparts K and L?  

( 3:30 PM	Break  

Completed ICR Mosquito Repellent Efficacy Study A117

( 3:45 AM	EPA Science and Ethics Assessment of Completed ICR Mosquito
Repellent Efficacy Study A117– Mr. Kevin Sweeney (OPP, EPA) and Mr.
John Carley (OPP, EPA) 

( 4:45 PM	Public comments 

( 5:15 PM	Adjournment - Celia Fisher, Ph.D. (HSRB Chair) and Paul Lewis,
Ph.D. (HSRB DFO)

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

HUMAN STUDIES REVIEW BOARD (HSRB)

JUNE 24-25, 2008 *

PUBLIC MEETING

Wednesday, June 25, 2008 

Environmental Protection Agency 

Conference Center - Lobby Level 

One Potomac Yard (South Bldg.)

2777 S. Crystal Drive

 Arlington, VA 22202 

( 8:30 AM	Convene Meeting –  Celia Fisher, Ph.D. (HSRB Chair)

( 8:35 AM	Follow-up From Previous Day’s Discussion – Mr. William
Jordan (OPP, EPA)  

Completed ICR Mosquito Repellent Efficacy Study A117

( 8:45 AM	Board Discussion        

Is this study sufficiently sound, from a scientific perspective, to be
used, in conjunction with other information, to assess the repellent
efficacy of the formulations tested against mosquitoes of the genus
Culex?     

Does available information support a determination that this study was
conducted in substantial compliance with subparts K and L of EPA
regulations at 40 CFR Part 26?  

Review of April 9-10, 2008 HSRB Meeting Report

( 9:45 AM	Review Process - Celia Fisher, Ph.D. (HSRB Chair)

( 9:55 AM	Public Comments

( 10:15 AM	Break  

( 10:30 AM	Board Discussion and Decision on Report - Celia Fisher, Ph.D.
(HSRB Chair)   

( 12:30 PM	Concluding Remarks  - Mr. William Jordan (OPP, EPA)  

( 12:35 PM	Adjournment - Celia Fisher, Ph.D. (HSRB Chair) and Paul
Lewis, Ph.D. (HSRB DFO)

* Please be advised that agenda times are approximate and subject to
change. For further information, please contact the Designated Federal
Officer for this meeting, Paul Lewis, via telephone: (202) 564-8381 or
email:   HYPERLINK "mailto:lewis.paul@epa.gov"  lewis.paul@epa.gov  

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