
[Federal Register Volume 75, Number 237 (Friday, December 10, 2010)]
[Notices]
[Pages 76982-76984]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2010-31079]


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ENVIRONMENTAL PROTECTION AGENCY

[FRL-9237-6; Docket ID No. EPA-HQ-ORD-2007-0664]


Integrated Risk Information System (IRIS); Announcement of 
Availability of Literature Searches for IRIS Assessments

AGENCY: Environmental Protection Agency.

ACTION: Announcement of availability of literature searches for IRIS 
assessments; request for information.

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SUMMARY: The U.S. Environmental Protection Agency (EPA) is announcing 
the availability of literature searches for four IRIS assessments, 
acetaldehyde (CAS No. 75-07-0), hexachlorobutadiene (CAS No. 87-68-3), 
hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) (CAS No. 121-82-4), and 
naphthalene (CAS No. 91-20-3) and requesting scientific information on 
health effects that may result from exposure to these chemical 
substances. EPA's IRIS is a human health assessment program that 
evaluates quantitative and qualitative risk information on effects that 
may result from exposure to specific chemical substances found in the 
environment.

DATES: EPA will accept information related to the specific substances 
included herein as well as any other compounds being assessed by the 
IRIS Program. Please submit any information in accordance with the 
instructions provided below.

ADDRESSES: Please submit relevant scientific information identified by 
docket ID number EPA-HQ-ORD-2007-0664, online at http://www.regulations.gov (EPA's preferred method); by e-mail to 
ord.docket@epa.gov; mailed to Office of Environmental Information (OEI) 
Docket (Mail Code: 2822T), U.S. Environmental Protection Agency, 1200 
Pennsylvania Ave., NW., Washington, DC 20460-0001; or by hand delivery 
or courier to EPA Docket Center, EPA West, Room 3334, 1301 Constitution 
Ave., NW., Washington, DC, between 8:30 a.m. and 4:30 p.m. Monday 
through Friday, excluding legal holidays. Information on a disk or CD-
ROM should be formatted in Word or as an ASCII file, avoiding the use 
of special characters and any form of encryption, and may be mailed to 
the mailing address above.

FOR FURTHER INFORMATION CONTACT: For information on the IRIS program, 
contact Karen Hammerstrom, IRIS Program Deputy Director, National 
Center for Environmental Assessment,

[[Page 76983]]

(mail code: 8601D), Office of Research and Development, U.S. 
Environmental Protection Agency, Washington, DC 20460; telephone: (703) 
347-8642, facsimile: (703) 347-8689; or e-mail: FRNquestions@epa.gov.
    For general questions about access to IRIS, or the content of IRIS, 
please call the IRIS Hotline at (202) 566-1676 or send electronic mail 
inquiries to hotline.iris@epa.gov.

SUPPLEMENTARY INFORMATION: 

Background

    EPA's IRIS is a human health assessment program that evaluates 
quantitative and qualitative risk information on effects that may 
result from exposure to specific chemical substances found in the 
environment. Through the IRIS Program, EPA provides the highest quality 
science-based human health assessments to support the Agency's 
regulatory activities. The IRIS database contains information for more 
than 540 chemical substances that can be used to support the first two 
steps (hazard identification and dose-response evaluation) of the risk 
assessment process. When supported by available data, IRIS provides 
oral reference doses (RfDs) and inhalation reference concentrations 
(RfCs) for chronic noncancer health effects as well as assessments of 
potential carcinogenic effects resulting from chronic exposure. 
Combined with specific exposure information, government and private 
entities use IRIS to help characterize public health risks of chemical 
substances in a site-specific situation and thereby support risk 
management decisions designed to protect public health.
    This data call-in is a step in the IRIS process. As literature 
searches are completed, the results will be posted on the IRIS Web site 
(http://www.epa.gov/iris). The public is invited to review the 
literature search results and submit additional information to EPA.

Request for Public Involvement in IRIS Assessments

    EPA is soliciting public involvement in assessments on the IRIS 
agenda, including new assessments starting in 2011. While EPA conducts 
a thorough literature search for each chemical substance, there may be 
unpublished studies or other primary technical sources that are not 
available through the open literature. EPA would appreciate receiving 
scientific information from the public during the information gathering 
stage for the assessments listed in this notice or any other 
assessments on the IRIS agenda. Interested persons may provide 
scientific analyses, studies, and other pertinent scientific 
information. While EPA is primarily soliciting information on new 
assessments, the public may submit information on any chemical 
substance at any time.
    This notice provides (1) a list of new IRIS assessments for which 
literature searches have recently become available; and (2) 
instructions to the public for submitting scientific information to EPA 
pertinent to the development of assessments.
    EPA is announcing the availability of additional literature 
searches on the IRIS Web site (http://www.epa.gov/iris). The public is 
invited to review the literature search results and submit additional 
information to EPA. Literature searches are now available for 
acetaldehyde (CAS No. 75-07-0), hexachlorobutadiene (CAS No. 87-68-3), 
hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) (CAS No. 121-82-4), and 
naphthalene (CAS No. 91-20-3) at http://www.epa.gov/iris under ``IRIS 
Agenda and Literature Searches.'' Additional literature searches will 
be posted as they are completed. Availability will be announced in the 
Federal Register. Instructions on how to submit information are 
provided below under General Information.

General Information

    Submit your comments, identified by Docket ID No. EPA-HQ-ORD-2007-
0664 by one of the following methods:
     http://www.regulations.gov: Follow the on-line 
instructions for submitting comments.
     E-mail: ORD.Docket@epa.gov.
     Fax: 202-566-1753.
     Mail: Office of Environmental Information (OEI) Docket, 
(Mail Code: 2822T), U.S. Environmental Protection Agency, 1200 
Pennsylvania Ave., NW., Washington, DC 20460. The phone number is 202-
566-1752.
     Hand Delivery: The OEI Docket is located in the EPA 
Headquarters Docket Center, EPA West Building, Room 3334, 1301 
Constitution Ave., NW., Washington, DC. The EPA Docket Center's Public 
Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through 
Friday, excluding legal holidays. The telephone number for the Public 
Reading Room is 202-566-1744. Such deliveries are only accepted during 
the docket's normal hours of operation, and special arrangements should 
be made for deliveries of boxed information. If you provide information 
by mail or hand delivery, please submit one unbound original with pages 
numbered consecutively, and three copies of the comments. For 
attachments, provide an index, number pages consecutively with the main 
text, and submit an unbound original and three copies.
    Instructions: Direct your comments to Docket ID No. EPA-HQ-ORD-
2007-0664. It is EPA's policy to include all comments it receives in 
the public docket without change and to make the comments available 
online at http://www.regulations.gov, including any personal 
information provided, unless a comment includes information claimed to 
be Confidential Business Information (CBI) or other information whose 
disclosure is restricted by statute. Do not submit information that you 
consider to be CBI or otherwise protected through http://www.regulations.gov or e-mail. The http://www.regulations.gov Web site 
is an ``anonymous access'' system, which means EPA will not know your 
identity or contact information unless you provide it in the body of 
your comment. If you send an e-mail comment directly to EPA without 
going through http://www.regulations.gov, your e-mail address will be 
automatically captured and included as part of the comment that is 
placed in the public docket and made available on the Internet. If you 
submit an electronic comment, EPA recommends that you include your name 
and other contact information in the body of your comment and with any 
disk or CD-ROM you submit. If EPA cannot read your comment due to 
technical difficultiesand cannot contact you for clarification, EPA may 
not be able to consider your comment. Electronic files should avoid the 
use of special characters, any form of encryption, and be free of any 
defects or viruses. For additional information about EPA's public 
docket visit the EPA Docket Center homepage at http://www.epa.gov/epahome/dockets.htm.
    Docket: All documents in the docket are listed in the http://www.regulations.gov index. Although listed in the index, some 
information is not publicly available, e.g., CBI or other information 
whose disclosure is restricted by statute. Certain other material, such 
as copyrighted material, will be publicly available only in hard copy. 
Publicly available docket materials are available either electronically 
in http://www.regulations.gov or in hard copy at the OEI Docket in the 
EPA Headquarters Docket Center.


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    Dated: December 3, 2010.
Darrell A. Winner,
Acting Director, National Center for Environmental Assessment.
[FR Doc. 2010-31079 Filed 12-9-10; 8:45 am]
BILLING CODE 6560-50-P


