1
of
4
DRAFT
3/
16/
06
UNITED
STATES
ENVIRONMENTAL
PROTECTION
AGENCY
HUMAN
STUDIES
REVIEW
BOARD
(
HSRB)
PUBLIC
MEETING
Tuesday,
April
4,
2006
Holiday
Inn
 
Rosslyn
at
Key
Bridge
1900
North
Fort
Myer
Drive
Arlington,
VA
22209
703­
807­
2000
HSRB
WEB
SITE
http://
www.
epa.
gov/
osa/
hsrb/
Docket
Telephone:
(
202)
566
1752
Docket
Number:
EPA­
HQ­
ORD­
2006­
0187
C
8:
30
AM
Introduction
and
Identification
of
Board
Members
 
HSRB
Chair
C
8:
45
AM
Welcome
 
George
Gray,
Ph.
D.
(
EPA
Science
Advisor)

C
9:
00
AM
Opening
Remarks
 
Ms.
Susan
Hazen
(
Acting
Assistant
Administrator,
Office
of
Prevention,
Pesticides
and
Toxic
Substances,
EPA)

C
9:
15
AM
Meeting
Administrative
Procedures
­
Paul
Lewis,
Ph.
D.
(
Designated
Federal
Officer,
HSRB,
EPA)

Session
1:
Introduction
C
9:
20
AM
Session
1
Overview
 
Mr.
William
Jordan
(
Office
of
Pesticide
Programs
[
OPP],
EPA)

C
9:
25
AM
Summary
of
EPA's
Protections
for
Subjects
of
Human
Research
­
Mr.
William
Jordan
(
OPP,
EPA)

C
10:
05
AM
Break
C
10:
20
AM
EPA,
OPP
Assessment
of
Ethical
Conduct
of
Human
Studies
 
Mr.
John
Carley
(
OPP,
EPA)

C
10:
45
AM
EPA,
OPP
Approach
to
Assessing
Human
Health
Risks
of
Pesticides
Using
Data
From
Human
Studies
 
Mr.
Michael
Metzger
(
OPP,
EPA)

C
11:
05
AM
EPA,
OPP
Assessment
of
Individual
Human
Studies
 
Ray
Kent,
Ph.
D.
(
OPP,
EPA)

C
11:
35
AM
EPA,
OPP
Policy
on
"
The
Use
of
Data
on
Cholinesterase
Inhibition
for
Risk
Assessment
of
Organophosphorous
and
Carbamate
Pesticides"
 
Anna
Lowit,
Ph.
D.
(
OPP,
EPA)

C
12:
00
PM
Lunch
2
of
4
Session
2:
Carbamate
Pesticides
C
1:
00
PM
Session
2
Overview
 
Anna
Lowit,
Ph.
D.
(
OPP,
EPA)

C
1:
05
PM
Science
and
Ethics
of
Aldicarb
Human
Studies
­
Linda
Taylor,
Ph.
D.
(
OPP,
EPA)
and
Mr.
John
Carley
(
OPP,
EPA)

C
1:
30
PM
Science
and
Ethics
of
Methomyl
Human
Studies
 
Elissa
Reaves,
Ph.
D.
(
OPP,
EPA)
and
Mr.
John
Carley
(
OPP,
EPA)

C
2:
00
PM
Science
and
Ethics
of
Oxamyl
Human
Studies
 
Elissa
Reaves,
Ph.
D.
(
OPP,
EPA)
and
Mr.
John
Carley
(
OPP,
EPA)

C
2:
45
PM
Break
C
3:
00
PM
Public
Comments
on
Session
2
C
4:
15
PM
HSRB
Writing
Session
C
5:
15
PM
Adjourn
3
of
4
UNITED
STATES
ENVIRONMENTAL
PROTECTION
AGENCY
HUMAN
STUDIES
REVIEW
BOARD
(
HSRB)
PUBLIC
MEETING
Wednesday,
April
5,
2006
Holiday
Inn
 
Rosslyn
at
Key
Bridge
1900
North
Fort
Myer
Drive
Arlington,
VA
22209
703­
807­
2000
HSRB
WEB
SITE
http://
www.
epa.
gov/
osa/
hsrb/
ORD
Docket
Telephone:
(
202)
564
1752
ORD
Docket
Number:
EPA­
HQ­
ORD­
2006­
0187
C
8:
30
AM
Convene
Meeting
 
HSRB
Chair
C
8:
40
AM
Followup
From
Previous
Day's
Discussion
 
Mr.
William
Jordan
(
OPP,
EPA)

C
8:
50
AM
Board
Discussion
C
10:
15
PM
Break
Session
3:
Organophosphate
Pesticides
C
10:
30
PM
Session
3
Overview
 
Ray
Kent,
Ph.
D.
(
OPP,
EPA)

C
10:
35
AM
Science
and
Ethics
of
AZM
Human
Studies
 
John
Doherty,
Ph.
D.
(
OPP,
EPA)
and
Mr.
John
Carley
(
OPP,
EPA)

C
11:
00
AM
Science
and
Ethics
of
DDVP
Human
Studies
 
Ray
Kent,
Ph.
D.
(
OPP,
EPA)
and
Mr.
John
Carley
(
OPP,
EPA)

C
11:
45
PM
Lunch
C
12:
45
PM
Public
Comments
on
Session
3
C
2:
00
PM
Board
Discussion
C
3:
15
PM
Break
Session
4:
Other
Pesticides
C
3:
30
PM
Session
Overview
 
Ray
Kent,
Ph.
D.
(
OPP,
EPA)

C
3:
35
PM
Science
and
Ethics
of
Ethephon
­
Ray
Kent,
Ph.
D.
(
OPP,
EPA)
and
Mr.
John
Carley
(
OPP,
EPA)

C
4:
00
PM
Science
and
Ethics
of
Amitraz
Human
Studies
 
John
Liccione,
Ph.
D.
(
OPP,
EPA)
and
Mr.
John
Carley
(
OPP,
EPA)

C
4:
30
PM
HSRB
Writing
Session
C
5:
30
PM
Adjournment
4
of
4
UNITED
STATES
ENVIRONMENTAL
PROTECTION
AGENCY
HUMAN
STUDIES
REVIEW
BOARD
(
HSRB)
PUBLIC
MEETING
Thursday,
April
6,
2006
Holiday
Inn
 
Rosslyn
at
Key
Bridge
1900
North
Fort
Myer
Drive
Arlington,
VA
22209
703­
807­
2000
HSRB
WEB
SITE
http://
www.
epa.
gov/
osa/
hsrb/
ORD
Docket
Telephone:
(
202)
564
1752
ORD
Docket
Number:
EPA­
HQ­
ORD­
2006­
0187
C
8:
30
AM
Convene
Meeting
 
HSRB
Chair
C
8:
45
AM
Followup
From
Previous
Day's
Discussion
 
Mr.
William
Jordan
(
OPP,
EPA)

C
9:
00
PM
Science
and
Ethics
of
Sodium
Cyanide
Human
Studies
 
William
Dykstra,
Ph.
D.
(
OPP,
EPA)
and
Mr.
John
Carley
(
OPP,
EPA)

C
9:
30
AM
Public
Comments
on
Session
4
C
10:
30
AM
Break
C
10:
45
AM
Board
Discussion
C
12:
00
PM
Lunch
C
1:
00
PM
HSRB
Writing
Session
C
4:
30
PM
Adjournment
Please
be
advised
that
agenda
times
are
approximate.
For
further
information,
please
contact
the
Designated
Federal
Officer
for
this
meeting,
Paul
Lewis
via
telephone:
(
202)
564­
8381
or
email:
lewis.
paul@
epa.
gov
