Ad-hoc reviewers selected for the May 8-11, 2023 Science Advisory Committee on Chemicals (SACC) review of two draft documents on Principles of Cumulative Risk Assessment (CRA) and a Proposed Approach of CRA of High-Priority Phthalates and a Manufacturer-Requested Phthalate under TSCA 
The expertise of the SACC members was augmented by adding the following ad-hoc reviewers, who are temporary participants in SACC activities, providing additional scientific expertise.
Michael A. Babich, PhD
US Consumer Product Safety Commission-Retired

Affiliation:
Director, Division of Toxicology & Risk Assessment (retired February 2023) U.S. Consumer Product Safety Commission, Rockville, Maryland

Expertise: 
Risk assessment

Education: 
PhD in Bioorganic Chemistry, Pennsylvania State University; MS in Chemistry, Pennsylvania State University; BA in Chemistry, La Salle University, PA.

Experience Summary: 
Dr. Michael Babich served as the Director of the Division of Toxicology & Risk Assessment at the U.S. Consumer Product Safety Commission (CPSC) from 2013 until his retirement in 2023. He previously served as a staff scientist at CPSC, where he was the principal author of numerous CPSC exposure and risk assessments involving chronic hazards associated with consumer products, including flame retardant chemicals in upholstered furniture and diisononyl phthalate in children's products. He has managed numerous regulatory and research projects, including the CPSC chronic hazard risk assessment guidelines, and the Chronic Hazard Advisory Panel (CHAP) on phthalates, and coordinated the agency's Chemical Hazards Program for 9 years. This work contributed to the development of seven federal regulations, four national voluntary standards, and the CPSC risk assessment guidelines. Prior to joining CPSC, Dr. Babich was engaged in basic research in the field of carcinogenesis, mutagenesis, and DNA repair. Dr. Babich received postdoctoral training at the University of Rochester Medical Center and the National Cancer Institute (NCI), National Institutes of Health (NIH). He previously worked as a Research Associate at the Armed Forces Radiobiology Research Institute (AFRRI).

Panel Experience: 
Interagency Scientific Review Group, Report on Carcinogens, National Toxicology Program (NTP), 2008-2010; Study Design Groups for Antimony Trioxide and Tris(2-chloropropyl) Phosphate, National Toxicology Program, 2007; Peer reviewer for "Interaction Profile for Carbon Monoxide, Formaldehyde, Methylene Chloride, Nitrogen Dioxide, and Tetrachloroethylene" and "Interaction Profile for Chloroform, 1,1-Dichloroethylene, Trichloroethylene, and Vinyl Chloride," Agency for Toxic Substances and Disease Registry, 2007; Federal Technical Advisor, High Production Volume Chemical Workgroup, National Pollution Prevention and Toxics Advisory Committee (NPPTAC), U.S. Environmental Protection Agency, 2005

Joseph M. Braun, RN, MSPH, PhD
Brown University
Affiliation:
Associate Professor, Department of Epidemiology, Brown University, Providence, Rhode Island.

Expertise: 
Epidemiology; Chemical Mixtures; Pediatrics; Endocrine Disruptors; Exposure Assessment; Obesity; Neurodevelopment

Education: 
BS in Biochemistry, University of Wisconsin, Madison; BS in Nursing, University of Wisconsin, Milwaukee; MSPH in Epidemiology, University of North Carolina, Chapel Hill; PhD in Epidemiology, University of North Carolina, Chapel Hill

Experience Summary: 
Dr. Braun is an Associate Professor in the Department of Epidemiology and Director of the Center for Children's Environmental Health at the Brown University School of Public Health. He was formerly a school nurse in Milwaukee, WI before receiving his master's and doctoral degrees in Epidemiology from the University of North Carolina, Chapel Hill. He completed postdoctoral training in environmental health at the Harvard School of Public Health. For 17 years, Dr. Braun has been identifying modifiable risk factors of pediatric diseases. Working with an interdisciplinary team that includes epidemiologists, biostatisticians, exposure scientists, physicians, and engineers, he studies the health effects of environmental pollutant exposures before conception and during gestation, infancy, childhood, and adolescence. Dr. Braun's research foci include endocrine disrupting chemicals, toxic metals, obesity, cardiometabolic health, and pediatric neurodevelopmental disorders. His research group applies advanced biostatistical techniques to longitudinal cohort studies in order to quantify the health effects of chemical mixtures and identify periods of heightened susceptibility to chemical exposures. Moreover, Dr. Braun is using untargeted metabolomics and DNA methylation to understand biological pathways underlying the potential effect of chemical exposures. Dr. Braun is currently the chair of the Social and Environmental Determinants of Health Study Section (NIH). In addition to the panel experience listed below, Dr. Braun served as an ad hoc reviewer on six other NIH study sections

Panel Experience: 
Served as an ad hoc reviewer on six other NIH study sections. EPA's Integrated Science Assessment (ISA) for Pb (2022); NTP report on the Immunotoxicity Associated with Exposure to PFOA or PFOS (2016). NTP/ODS panel on Identifying Research Needs for Assessing Safe Use of High Intakes of Folic Acid (and a co-author of the associated monograph; 2015)

Antonia M. Calafat, PhD
Center for Disease Control and Prevention


Affiliation:
Chief, Organic Analytical Toxicology Branch, Division of Laboratory Sciences at the Centers for Disease Control and Prevention (CDC), Atlanta, Georgia

Expertise: 
Human exposures to environmental chemicals including phthalates with a focus on Biomonitoring and Public Health 

Education: 
PhD in Chemistry, University of the Balearic Islands (UBI), Spain; MS in Chemistry, UBI; BS in Chemistry, UBI
 
Experience Summary: 
Dr. Calafat has 26 years of laboratory biomonitoring science expertise at CDC. She established and led world-recognized biomonitoring programs at CDC to assess chemical exposures of public health concern (e.g., phthalates and other plasticizers, PFAS, bisphenol A, pesticides). She leads CDC's biomonitoring programs for assessing human exposure to chemicals added to consumer and personal-care products such as phthalates and phenols; flame retardants; pesticides; polycyclic aromatic hydrocarbons; and persistent organic pollutants including polybrominated diphenyl ethers; polychlorinated dibenzo-p-dioxins, furans, and biphenyls; and PFAS. In 2019, she received the Excellence in Exposure Science Award given by the International Society of Exposure Science. Since 2017, she is the co-Editor-in-Chief of the International Journal of Hygiene and Environmental Health.

Panel Experience: 
FAO/WHO Expert Meeting on Bisphenol A (Ottawa, Canada) (November 2010) as vice-chairperson; U.S. Food and Drug Administration Science Board Bisphenol A Subcommittee (August 2008 - October 2008); Center for the Evaluation of Risks to Human Reproduction of the National Toxicology Program expert panel to evaluate the reproductive and developmental toxicity of genistein and soy formula (March 2006)


Robert E. Chapin, Ph.D.
Pfizer Global Research and Development-Retired



Affiliation: 
Former Senior Research Fellow (Retired), Pfizer Global Research and Development, Groton, Connecticut

Expertise: 
In vitro predictive toxicology; pre-conception reproductive toxicology

Education:
PhD in Pharmacology, University of North Carolina, Chapel Hill; BA in Biology, Earlham College

Experience Summary: 
Dr. Robert Chapin has recently retired from his position as a Senior Research Fellow and member of the Developmental and Reproductive Toxicology Center of Expertise at Pfizer Global Research and Development in Groton, Connecticut. He received his PhD degree in 1980 from UNC-Chapel Hill in Pharmacology and subsequently post-doctored for 2 years at the Chemical Industry Institute of Toxicology. This was followed by 18 years at the National Institute of Environmental Health Sciences (NIEHS), as a Senior Staff Fellow in the National Toxicology Program, then as a Principal Investigator, and then Laboratory Head. His area of expertise is pre-conception reproductive toxicology in male and female; however, he also worked hard in the area of in vitro predictive toxicology. He developed advanced in vitro culture methods for exploring mechanisms of reproductive toxicology and helped pioneer the integrated use of molecular, biochemical, histologic, and in vitro methods to address mechanistic questions in reproductive toxicology.

Panel Experience: 
Dr. Chapin has served as an ad hoc member on several Scientific Advisory Panels for the U.S. Environmental Protection Agency (U.S. EPA) specifically the National Research Council's Low Dose Non-Monotone Panel (2013) and had previously worked on numerous International Life Sciences Institute committees and publications (2009-2011). Dr. Chapin currently serves as Chair of the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel.

Raymond M. David, PhD
David Tox, LLC


Affiliation: 
Principal, David Tox, LLC, Sarasota, Florida

Expertise: 
Mammalian Toxicology

Education:
PhD in Pharmacology, University of Louisville; MS in Biology, Loyola University of Chicago; BS in Biology, Marquette University

Experience Summary: 
Dr. Raymond David has been an independent consultant for 6 years and is an adjunct (courtesy) professor at the University of Florida, Department of Physiological Sciences, College of Veterinary Medicine. Dr. David retired from the Manager of Toxicology for Industrial Chemicals position at BASF Corporation in 2016. Dr. David worked for 8 years (1983-1991) at Microbiological Associates in Bethesda, Maryland where he managed the Inhalation and Mammalian Toxicology Departments. He later moved to Eastman Kodak in Rochester, New York, where he worked as Senior Toxicologist for over 14 years (1991-2006). At Kodak, Dr. David was responsible for scientific stewardship of phthalate esters at Eastman Kodak, and that responsibility extended to BASF. Dr. David has over 15 years of experience studying the toxicology of phthalates and has published 14 peer-reviewed papers and 3 book chapters on phthalate esters toxicology. He has participated in the American Chemistry Council's Phthalate Esters Panel as chair of the toxicology research group, and has provided information on phthalates to the media, and state and federal legislative bodies. Dr. David was also an observer to the International Agency for Research on Cancer (IARC) Working Group in 2000 which reviewed di(2-ethylhexyl) phthalate (DEHP) and di(2-ethylhexyl) adipate (DEHA). Dr. David was certified by the American Board of Toxicology in 1985 and subsequently recertified in 1990, 1995, 2000, 2005, 2010, and 2015.

Panel Experience:
Expert Panel of the Center for Evaluating Risks to Human Reproduction for 1-bromopropane (2001); Industry observer to the IARC Working Group on Carcinogens (1998, 2000) 

Stephanie, M. Engel, PhD
University of North Carolina

Affiliation:
Professor of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

Expertise: 
Environmental epidemiology, Perinatal and neurodevelopmental epidemiology.

Education: 
BA in Psychology, University of California at San Diego; BS in Animal Physiology and Neuroscience, University of California at San Diego; MSPH in Epidemiology, University of North Carolina at Chapel Hill; PhD in Epidemiology, University of North Carolina at Chapel Hill

Experience Summary: 
Dr. Engel is a Professor of Epidemiology, with 20 years of research and teaching experience in perinatal and environmental epidemiology. She is the current Director of an EPA-funded Early Life Center, PI of multiple NIH-funded R01s, and Deputy Director of the NIEHS-funded P30 Center for Environmental Health and Susceptibility. She has graduated 8 doctoral students, 6 master's students, and served on the doctoral committee of over twenty additional students across multiple academic disciplines, from Toxicology to Biostatistics. Dr. Engel's research considers the impact of environmental exposures and innate susceptibility factors on adverse pregnancy outcomes and neurodevelopmental impairment in children. She has led multiple national and international studies of prenatal and early life toxicant exposures in relation to child development, has over 130 peer reviewed publications, and has led collaborative research amounting to over $11M in federal funding. Her research expertise is particularly focused on endocrine disrupting compounds and complex exposure mixtures, utilizing biomarkers of exposure to estimate associations with neurodevelopmental outcomes.

Panel Experience: 
NIH/CSR Study Sections: Temporary Member: ZRG1 IRAP-Q 01 (June 2009), ZRG1 PSE-F 95 (S), (June 2009), ZES1 SET-V 01, NIEHS: "Assessing and Addressing Community Exposures to Environmental Contaminants", (July 2009), ZRG1 IRAP-Q 01 (June 2010), ZRG1 IRAP-Q 01 (June 2010), ZRG1-SPSS (Feb 2012), ZRG1-NAME (Feb 2013), ZRG1-NAME (Dec 2013), NIEHS Special Emphasis Panel for Career Awards (K22 & K23) ZES1 LKB-D (C) 1 (April 2016), ZRG1-IRAP (Feb 2016), NIH Fellowships: Risk, Prevention and Health Behavior ZRG1 F16-M (09) F (March 2017) Standing Member: ZRG1-IRAP (2017-2021); Other Workgroups: Member of Endocrine Disruptors Workgroup, "Optimizing Expose Metrics for the National Children's Study" (2010); Member, Institute of Medicine (IOM) Committee for the Review of the Health Effects in Vietnam Veterans of Exposure to Herbicides 9th Biennial Update (2012-2014); Reviewer, Division of Intramural Population Health Research (DIPHR), National Institute of Child Health and Human Development (NICHD) (2016); External Advisory Board Member (Mount Sinai NIEHS P30)(2017-ongoing); Chair, External Advisory Board, Center for Population Health Research, University of Montana

Mary A. Fox, PhD, MPH
Johns Hopkins University
Affiliation:
Assistant Professor and Co-Director, Risk Sciences and Public Policy Institute Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland

Expertise: 
Human Health Risk Assessment: Applying epidemiological methods and data to understand combined exposures to chemical and non-chemical stressors for cumulative risk assessment

Education: 
PhD, Environmental and Occupational Health Policy, Johns Hopkins University; MPH, Environmental Studies, University of Rochester; BS, Biology, State University of New York at Albany

Experience Summary: 
Dr. Fox is an Assistant Professor in the Department of Health Policy and Management and the co-director of the Risk Sciences and Public Policy Institute at the Johns Hopkins Bloomberg School of Public Health. She has 18 years of experience teaching as core faculty of the Risk Sciences certificate program leading courses in quantitative risk assessment methods and risk policy, management and communication. Dr. Fox's research is focused on human health risk assessment as a part of environmental policy making, particularly approaches to cumulative and chemical mixtures risk assessment. Dr. Fox has made key contributions to the development and application of cumulative risk methods to inform community environmental health and environmental justice and occupational health policies. Dr. Fox has expertise in risk assessment of air toxics, metal mixtures, phthalates, volatile organic solvents and PCBs. Dr. Fox has served on four National Academies' committees: Veterans and Agent Orange, Update 11 (2017-2018); Gulf War and Health, Volume 10: Update of Health Effects of Serving in the Gulf War (2014-2016); Long-Term Health Consequences of Exposure to Burn Pits in Iraq and Afghanistan (2010-2011); and Phthalates and Cumulative Risk Assessment: The Tasks Ahead (2007-2008).

Panel Experience: 
NIEHS P42 Superfund Review (2016); Agency for Toxic Substances and Disease Registry, Camp Lejeune Drinking Water Public Health Assessment (2015); U.S. EPA, Community-Focused Exposure and Risk Screening Tool (C-FERST) (2013); U.S. FDA, Center for Food Safety and Nutrition iRisk Model (2013); NIEHS Children's Environmental Health and Disease Prevention Research Review (2012); U.S. EPA, Office of Water's "Fluoride: Exposure and Relative Source Contribution Analysis" (2010); U.S. EPA and Department of Agriculture, "Risk Assessment of Spent Foundry Sands in Soil-Related Applications (2009); U.S. Pharmacopeial Convention (USP), Expert Panel on Dietary Supplements Safety Modeling (2013-2014); US EPA Science Advisory Board ad hoc Perchlorate Advisory Panel (2012-2013); US EPA Peer Consultation Workshop on Cumulative Risk Assessment of Phthalates (2010); Four National Academies' committees: Veterans and Agent Orange, Update 11 (2017-2018); Gulf War and Health, Volume 10: Update of Health Effects of Serving in the Gulf War (2014-2016); Long-Term Health Consequences of Exposure to Burn Pits in Iraq and Afghanistan (2010-2011); and Phthalates and Cumulative Risk Assessment: The Tasks Ahead (2007-2008).

Richard, C, Hertzberg, PhD
Biomathematics Counseling
Affiliation:
Private consultant (Biomathematics Consulting), Atlanta, Georgia

Expertise: 
Biomathematics research developing dose-response methods to address toxicological interactions in chemical mixtures, and quantitative methods for health risk assessment of chemical mixtures 

Education: 
PhD in Biomathematics, University of Washington; BS in Mathematics, Harvey Mudd College, CA
 
Experience Summary: 
Dr. Richard Hertzberg is a private consultant with 17 years of experience working on federal and private contracts in the area of health risk assessment of chemical mixtures. He was an adjunct professor in Environmental Health at Emory University and taught the graduate course Risk Assessment I (2006-2014). Previously he was a mathematical statistician at the US EPA Office of Research and Development (ORD) leading the research program on risk assessment methods for chemical mixtures (1980-2006), including chairing the committee that wrote the 1986 chemical mixtures guidelines and the 2000 update (Supplementary Guidance), and co-authoring the 2003 Cumulative Risk Assessment Framework. He served a Special Term Appointment (2012-2015) at Argonne National Laboratory, Argonne, IL, where he contributed to methods and guidance on cumulative health risk assessment and to evaluations of greenspace health benefits and impacts. He served as adjunct faculty on PhD committees at Carnegie-Mellon (2006-08), and Texas A&M (1997-98) Universities, and on MS or MPH committees at Emory (2006-07), and Northwestern (1999-2000) Universities. He co-taught workshops on mixture risk assessment at the Society for Risk Analysis (2000-2021) and Society of Toxicology (2015, 2017, 2021). His research focus is defensible quantitative methods for mixtures risk

Panel Experience: 
External review panel of mixture risk guidance and interaction profiles, Agency for Toxic Substances and Disease Registry (ATSDR) (1998-2002); Expert review panel on mixture risk, Health Council of the Netherlands (1999-2002); External advisory committee, NIOSH Mixed Exposure Research Team (1998-2006); Expert review panel on the sulfolane reference dose for Alaska Department of Environmental Conservation (2014)

Kembra L. Howdeshell, MS, PhD
National Institute of Environmental Health Sciences


Affiliation:
Health Scientist at the Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina

Expertise: 
Developmental and Reproductive Toxicology; Endocrine Disruption; Mixtures Toxicology

Education: 
PhD in Biology, University of Missouri-Columbia; MS in Biological Sciences, Emporia State University, Emporia, KS; BS in Biology at Friends University, Wichita, KS
 
Experience Summary: 
Dr. Kembra Howdeshell is a Health Scientist in the Division of Translational Toxicology (DTT) (formerly the Division of the National Toxicology Program) at the National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC with 19 years of experience working as a toxicologist. She is a member of the Combined Exposures and Mixtures Program Management Team, which develops, reviews, and manages the mixtures research portfolio at the DTT, NIEHS (2020-present). Dr. Howdeshell is an active ad hoc Peer Reviewer for many journals and has served as Guest Editor for Birth Defect Research Journal (2017). She has served as a Discussant at the U.S. EPA Workshop, "Cumulative Risk Assessment of Phthalates," (December 2010), a Reviewer for the European Human Biomonitoring Initiative HBM4EU Workshop on mixture assessment of certain phthalates within the scope of task 5.2  -  derivation of human biomonitoring guidance values (HBM-G) (November 2020). Her primary research interests include developmental and reproductive toxicology, endocrine disruption, and mixtures toxicology

Panel Experience: 
Dr. Howdeshell does not have experience serving on a committee/panel style peer review. However, many of her publications (NTP monographs) at the DTT, NIEHS were reviewed by expert panels

Eric S.C. Kwok, MPhil, PhD, DABT
California Department of Pesticide Regulation



Affiliation:
Senior Toxicologist of the Exposure Assessment Section and the Human Exposure & Health Effect Modeling Section at the California Department of Pesticide Regulation, Sacramento, California

Expertise: 
Pesticide human health risk assessment; Pesticide exposure assessment in humans; Statistical analysis of data from FIFRA guideline mammalian toxicology studies and human exposure studies

Education: 
PhD in Environmental Toxicology, University of California, Riverside; MPhil in Biology, The Chinese University of Hong Kong; BSc (Hons) in Zoology (major) and Botany (minor), University of Hong Kong
 
Experience Summary: 
Dr. Kwok is a Senior Toxicologist of both the Exposure Assessment Section and Human Exposure & Health Effect Modeling Section at the California Department of Pesticide Regulation, where he supervises a team of modelers and toxicologists to conduct pesticide exposure assessments on agricultural handlers, reentry workers, and bystanders. Dr. Kwok has a combined twenty-two years of experience in conducting human exposure and health risk assessments of pesticides using different computational tools including stochastic human exposure assessment models and physiologically based pharmacokinetic models as well as performing statistical analyses on data derived from the Federal Insecticide, Fungicide, and Rodenticide Act guideline toxicology and exposure studies. Dr. Kwok has been a Diplomate of the American Board of Toxicology since 2006. His research focuses include applying 21st century computational techniques for characterizing pesticide exposures in humans based on human activities, product formulations, and use patterns. Dr. Kwok has published forty peer reviewed scientific papers and authored multiple research reports on pesticide health risk assessments and mitigation measures. He also received three Superior Accomplish Awards from the California EPA in recognition of his exceptional contributions and services to State Government

Panel Experience: 
FIFRA Scientific Advisory Panel meetings: Physiologically-based Pharmacokinetic Modeling (2017); and Proposed Guidelines for Efficacy Testing of Topically Applied Pesticides Used Against Certain Ectoparasitic Pests on Pets(2019)


Devon C. Payne-Sturges, DrPH, MPH, MEngr
University of Maryland

Affiliation:
Associate Professor, School of Public Health, University of Maryland, College Park, Maryland

Expertise: 
Expertise is in racial and economic disparities in exposures to environmental contaminants and associated health risks; Children's environmental health; Cumulative risk assessment and environmental health policy.

Education: 
DrPH and MPH in Environmental Health Sciences from Johns Hopkins University Bloomberg School of Public Health; MEngr in environmental engineering and BS in civil engineering from University of Virginia

Experience Summary: 
Dr. Payne-Sturges is an Associate Professor with the Maryland Institute for Applied Environmental Health in the Department of Epidemiology and Biostatistics at the School of Public Health, University of Maryland, College Park and has more than 20 years of experience in environmental health research and policy reform. Dr.Payne-Sturges was a Fulbright Specialist in Germany during fall semester of 2017 and currently serves on the Board of Scientific Counselors for the National Toxicology Program (2021 - present) and as the Inaugural Co-Chair of the Anti-Racism Task Force for the International Society for Environmental Epidemiology (2020 - present). Prior to joining UMD, Dr. Payne-Sturges worked at EPA for 12 years (2002- 2014), including 6 years (2008  -  2014) as Assistant Center Director for Human Health, with EPA's National Center for Environmental Research. Her research focuses on racial and economic disparities in exposures to environmental contaminants and associated health risks with the aim of improving the science used to make decisions about environmental policies that impact the health of communities and populations, especially vulnerable, low income and minority populations

Panel Experience: 
Board of Scientific Counselors for the National Toxicology Program (2021 - present). Board of Scientific Counselors for the National Center for Environmental Health/Agency for Toxic Substances and Disease Registry (2016-2019); National Academy of Sciences Environmental Health Matters Initiative (EHMI) Standing Committee (2019 - present); NIH Neurological, Aging and Musculoskeletal Epidemiology Study Section (2021); and Peer Review Panel for EPA's draft Planning and Scoping Guidelines for Cumulative Risk Assessment (June 2021)

Shirlee, Wei-Ling, Tan, PhD
Seattle and King County
Affiliation:
Senior Toxicologist, Public Health Department for Seattle & King County, Washington

Expertise: 
Cell and Molecular Biology (NAMs, EDCs), Toxicology (Human Health, Public Health), Equity and Social Justice (Cumulative Exposures and Disparities)

Education: 
PhD in Biology, University of California, San Diego (in coordination with the Salk Institute for Biological Sciences); BS, Duke University, NC

Experience Summary: 
Dr. Tan is the Senior Toxicologist for the Seattle & King County Public Health Department where she serves as a technical advisor for the department on risks related to chemical exposures, health outcomes, and policies. Dr. Tan has worked for 22 years on regulatory assay development for chemicals, and more recently at the community, local, state and national levels on science policy and actions around chemical exposures and effects. Dr. Tan serves on numerous advisory groups for WA State on chemical policies, toxics cleanup, and environmental justice (2017-present). She is the incoming Chair of EPA's Children's Health Protection Advisory Committee (CHPAC) (2020-2026). Dr. Tan previously worked for the Organization for Economic Cooperation and Development (OECD, 2010-2011) and the US EPA (2000-2011) on the development of regulatory assays for endocrine disrupting chemicals. She now serves on many OECD advisory and working groups. She worked for the Smithsonian Institution's National Zoological Park on pesticide misuse in Southeast Asia (2002-2008) and consults for the Endocrine Society on issues related to endocrine disrupting chemicals. Dr. Tan holds a PhD in cell and molecular biology from the University of San Diego, CA and conducted her postdoctoral research studying dopaminergic receptors and neurodegenerative pathways.

Panel Experience: 
Washington State: WA State Chemical Action Plan for PFAS (2016-2018); WA State Flame Retardant Stakeholder Advisory Committee (2018); Washington State Action Plan for Phthalates (2022-present); WA State Model Toxics Control Act Stakeholder and Tribal Advisory Committee (2019-present); and the WA State Environmental Justice Task Force Subcommittee on Community Engagement (2019-2020); National: EPA's Children's Health Protection Advisory Committee 2020-2026 (serving as chair starting March 2023-2026); Workshop 2 for the National Academies Committee on Variability and Relevance of Current Laboratory Mammalian Toxicity Tests and Expectations for New Approach Methods (NAMs) for use in Human Health Risk Assessment (May 2022); National Toxicology Program workshop titled Using New Approach Methodologies to Address Variability and Susceptibility Across Populations (October 2022); National Academies Children's Environmental Health Workshop session on Balancing Prevention and Uncertainty (August 2022); International: OECD Groups (2016-present) Advisory Group on Endocrine Disruptor Testing and Assessment; Working Party for Hazard Assessment; Expert Group for Molecular Screening and Toxicogenomics

Daniele Wikoff, PhD
ToxStrategies



Affiliation:
Principal and Practice Director at ToxStrategies, Asheville, North Carolina

Expertise: 
Toxicology; Risk assessment; Systematic Review; Peer-Review

Education: 
PhD in Toxicology, University of North Carolina at Chapel Hill; BS in Chemistry and Biology, Buena Vista University, IA

Experience Summary: 
Dr. Daniele Wikoff's  more than 15 years of consulting experience as a practitioner of both risk assessment and systematic review allows for a unique area of expertise in the evolving field of evidence-based toxicology. As the Health Sciences Practice Director, she has successfully implemented a turn-key process for conducting systematic assessments with a workflow facilitated by the combination of a multidisciplinary team and use of systematic review software and tools. Dr. Wikoff is a contributing author to the WHO Systematic Review Framework for Chemical Risk Assessment and is well-versed in both risk assessment and systematic review frameworks and guidance from authorities around the world. Dr. Wikoff serves as an Associate Editor for Toxicological Sciences, Regulatory Toxicology and Pharmacology, and Current Opinions in Toxicology. She routinely provides guest lectures and presents in Continuing Education courses and has led and/or participated in numerous workshops in the area of systematic review and risk assessment (see extended CV). Her research interests include methods development related to the definition and evaluation of data quality, and how elements of internal, construct, and external validity can be used to transparently inform conclusions and provide critical information to decision makers. Dr. Wikoff is involved in a number of global collaborations to advance the practice of evidence-based toxicology, highlighted by her membership on the Board of Trustees for the Evidence-Based Toxicology Collaboration, as well as Chair of the Science Advisory Council in which the primary role involves committee-style peer review of systematic review related projects (~2018-present).

Panel Experience: 
Member, Scientific Program Committee for the Society of Toxicology; Member for the National Academies of Science (NAS) committee on the review of the IRIS Protocol for Inorganic Arsenic; Scientific Quality Reviewer for the U.S. Department of Agriculture, a reviewer for the National Institute of Environmental Health Sciences  --  Virtual Consortium for Translational/Transdisciplinary Environmental Research, and expert reviewer for Health Canada as part of the Review of Biomonitoring Equivalents: Derivation of Biomonitoring Equivalents for Pentabromodiphenylether (PBDE-99), as well as on an EPA External Review Panel  --  An Exposure Assessment of Polybrominated Diphenyl Ethers 

Ami R. Zota, ScD, MS
Columbia University


Affiliation:
Associate Professor, Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York

Expertise: 
Exposure Science; Biomonitoring; Reproductive and Environmental Epidemiology; Maternal and Child Health; Environmental Justice; Health Disparities

Education: 
Doctor of Science (ScD), Harvard T.H. Chan School of Public Health; Master of Science (MS), Harvard T.H. Chan School of Public Health; Bachelor of Science in Public Health (BSPH), University of North Carolina at Chapel Hill (UNC-CH)

Experience Summary: 
Dr. Ami Zota, ScD, is an Associate Professor and population health scientist at Columbia University Mailman School of Public Health. Her scientific research focuses on the health disparities associated with exposure to toxic chemicals, including phthalates. Dr. Zota is an internationally recognized expert in environmental health science and environmental justice with specific expertise in exposure assessment, biomonitoring, epidemiology, health disparities, and maternal and reproductive health. She has spent more than sixteen years researching exposures to and health outcomes associated with phthalates and other toxic chemicals and has authored or coauthored more than sixty peer-reviewed scientific publications. Dr. Zota is the founding director of the Agents of Change in Environmental Justice program, which seeks to empower emerging leaders from historically excluded backgrounds in science and academia to reimagine solutions for a just and healthy planet by providing applied training in science communication, leadership, and public engagement with science. She is currently an Associate Editor at Environmental Health Perspectives and Environmental Justice. From 2017-2022, she was an Associate Editor at the Journal of Exposure Science and Environmental Epidemiology.

Panel Experience: 
Standing member of the Social and Environmental Determinants of Health (SEDH) NIH CSR Study Section (current); Standing member of the Infectious Disease, Reproductive Health, Asthma, and Pulmonary Conditions (IRAP) NIH CSR Study Section (2021-2022); Temporary, ad hoc member of 7 different NIH CSR Study Sections (2017-2021_; Research Solicitations For US EPA National Priorities: Per- and Polyfluorinated Substances (2018)

