Page
1
of
9
IUR
Petition
Review
Report
June
20,
2005
CASRNs
and
TSCA
Inventory
Chemical
Names:
96­
33­
3
2­
propenoic
acid,
methyl
ester
141­
32­
2
2­
propenoic
acid,
butyl
ester
Alternate
Chemical
Names
Used
in
Petitions:
One
of
the
petition
requests
used
non­
TSCA
Inventory
chemical
names
for
the
chemicals
listed
above.
See
Table
1
at
the
end
of
this
report
for
the
chemical
names
used
in
the
petition
request
that
differ
from
the
TSCA
Inventory
chemical
names.

Petitioners
and
Petition
Docket
Numbers:
The
Basic
Acrylic
Monomer
Manufacturers,
Inc.
(
BAMM)
OPPT­
2004­
0008
Dow
Chemical
Company
OPPT­
2004­
0016
BASF
Corporation
OPPT­
2004­
0044
Note:
These
petitions
contained
additional
petition
chemicals.
These
additional
petition
chemicals
are
addressed
in
other
petition
review
reports.

Summary
of
Decision:
The
petition
review
group
recommends
a
denial
for
these
petitions,
as
EPA
has
a
current
interest
in
the
processing
and
use
information
collected
under
the
Inventory
Update
Reporting
(
IUR)
rule
(
see
40
CFR
Part
710)
for
2­
propenoic
acid,
methyl
ester
(
CASRN
96­
33­
3)
and
2­
propenoic
acid,
butyl
ester
(
CASRN
141­
32­
2).
This
recommendation
is
based,
in
part,
on
the
determination
by
the
petition
review
group
that
there
is
a
direct
application
of
the
IUR
processing
and
use
information
to
complement
data
collected
by
or
identified
for
use
under
the
HPV
Challenge
Program.
See
Considerations
A,
C,
D,
and
E.

Background:
EPA
received
three
petitions
requesting
that
2­
propenoic
acid,
methyl
ester
(
CASRN
96­
33­
3)
and
2­
propenoic
acid,
butyl
ester
(
CASRN
141­
32­
2)
be
added
to
the
40
CFR
710.46(
b)(
2)(
iv)
list
of
specific
chemical
substances
which
are
exempt
from
the
reporting
of
industrial
processing
and
use
and
commercial/
consumer
use
information
required
by
40
CFR
710.52(
c)(
4).
The
chemical
substances
included
on
this
"
partial
exemption"
list
are
substances
for
which
EPA
has
previously
determined
that
there
is
a
low
current
interest
in
the
IUR
processing
and
use
information.
However,
as
stated
in
the
preamble
to
the
amendment
to
the
IUR
rule
promulgated
on
January
7,
2003
(
68
FR
854),
"...
the
need
for
processing
and
use
information
...
changes
over
time.
The
inclusion
of
a
chemical
substance
under
this
partial
exemption
is
not
based
on
the
potential
risks
of
a
chemical.
This
partial
exemption
is
solely
intended
to
provide
a
tool
to
assist
the
Agency
in
better
managing
the
collection
of
processing
and
use
information..."
and
is
also
"
based
on
the
Agency's
current
need
for
collecting
IURA
processing
and
use
information."
(
68
FR
855)
Additionally,
the
preamble
states,
"
In
determining
whether
there
is
low
current
interest
in
IURA
processing
and
use
information
related
to
a
specific
chemical
substance,
EPA
will
look
to
the
specific
circumstances
surrounding
the
chemical
in
question,
and
may
use
one
or
more
of
the
considerations
identified
below,
and/
or
considerations
not
identified
below,
to
make
an
informed
decision."
The
considerations
used
by
EPA
in
reviewing
these
1
See
the
attached
list
of
acronyms
at
the
end
of
this
report.

Page
2
of
9
petitions
and
an
analysis
of
how
those
considerations
relate
to
the
chemicals
identified
in
these
petitions
are
set
forth
below.

Discussion:
The
petition
review
group
considered
information
submitted
with
the
three
petitions,
as
well
as
other
information
including
(
but
not
limited
to):
whether
the
petition
substances
are
included
in
TRI,
IRIS,
or
IARC;
OECD
HPV
SIDS
program
status;
HPV
Challenge
Program
status;
and
the
petition
chemicals'
inclusion
in
other
regulatory
programs
administered
by
EPA.
1
The
petition
from
BAMM
(
docket
number
OPPT­
2004­
0008)
referred
EPA
to
the
OECD
HPV
SIDS
program
documents
for
this
chemical,
and
stated
that
the
information
provided
therein
should
be
sufficient
for
EPA
to
make
the
necessary
determination
to
include
this
chemical
on
the
list
of
partially
exempt
chemicals
under
the
IUR.
Additionally,
this
petition
stated
that
"
There
is
a
great
deal
of
information
on
the
basic
acrylates
use
and
exposure."

The
petition
from
the
Dow
Chemical
Company
(
docket
number
OPPT­
2004­
0016)
stated
that
these
chemicals
have
been
evaluated
as
part
of
the
OECD
HPV
SIDS
program
with
a
conclusion
of
low
priority
for
further
work
(
within
the
OECD
HPV
SIDS
program),
and
therefore,
processing
and
use
data
comparable
to
what
would
be
collected
under
the
IUR
are
currently
available.
Similarly,
the
petition
from
the
BASF
Corporation
(
docket
number
OPPT­
2004­
0044)
stated
that
these
chemicals
are
in
the
OECD
HPV
SIDS
program,
and
referred
EPA
to
the
completed
OECD
HPV
SIDS
program
documents.
The
petition
stated
that
the
BASF
Corporation
believes
that
the
information
in
the
OECD
HPV
SIDS
program
documents
demonstrates
that
there
is
little
need
at
this
time
to
collect
processing
and
use
information
for
these
chemicals.

The
petitions
did
not
link
information
furnished
in
the
petitions
to
specific
considerations
cited
in
40
CFR
710.46(
b)(
2)(
ii),
but
provided
general
citations,
as
noted
above,
to
OECD
HPV
SIDS
reviews.
General
citations
alone
are
of
limited
use
in
establishing
a
rationale
for
adding
a
chemical
to
the
IUR
partial
exemption
list.

Consideration
A:
Production
volume.

The
petition
review
group
found
that
there
was
at
least
one
site
reporting
in
2002
with
a
production
volume
for
each
of
these
chemicals
of
300,000
pounds
or
greater.

Consideration
B:
The
substance's
chemical
and
physical
properties
or
potential
for
persistence,
bioaccumulation,
health
effects,
or
environmental
effects.

The
petitions
did
not
identify
specific
information
from
the
OECD
HPV
SIDS
review
that
pertained
to
Consideration
B.
The
OECD
HPV
SIDS
program
SIAP
contained
summary
results
of
a
variety
of
studies
associated
with
human
health
and
the
environment
and
a
conclusion
that
Page
3
of
9
each
chemical
"
possesses
properties
indicating
a
hazard
for
human
health
and
the
environment"
(
Ref.
1).
For
instance,
the
SIAP
for
2­
propenoic
acid,
methyl
ester
(
CASRN
96­
33­
3)
indicated
that
the
chemical
is
moderately
acutely
toxic,
and
caused
respiratory
tract
irritation
following
repeated
inhalation
exposures.
Additionally,
the
chemical
induced
chromosome
aberrations
in
Chinese
hamster
cells
in
vitro.
The
chemical
showed
no
adverse
effects
on
reproductive
organs
in
repeated­
dose
inhalation
and
oral
studies.
It
is
acutely
toxic
to
aquatic
organisms.
The
SIAP
for
2­
propenoic
acid,
butyl
ester
(
CASRN
141­
32­
2)
indicated
that
acute
toxicity
is
low,
but
repeated
exposures
produced
effects
including
respiratory
tract
irritation
and
decreased
organ
weights.
The
chemical
caused
fetotoxic
effects
(
resorptions
and
reduced
number
of
live
fetuses)
at
maternally
toxic
concentrations.
It
is
acutely
toxic
to
aquatic
organisms.

The
substances
in
this
petition
have
hazard
and/
or
potential
exposure
properties
which
have
triggered
inclusion
in
different
government
programs.
For
example,
one
or
both
of
the
petitioned
chemicals
is
included
in
the
following
programs,
as
indicated:

Integrated
Risk
Information
System
(
IRIS)
­
IRIS
is
a
database
of
hazard
identification
and
dose­
response
assessment
information.
A
substance
is
selected
for
listing
in
IRIS
based
on
one
or
more
of
the
following
factors:
(
1)
Agency
statutory,
regulatory,
or
program
implementation
need;
(
2)
the
availability
of
new
scientific
information
or
methodology
that
might
significantly
change
current
IRIS
information;
(
3)
interest
to
other
levels
of
government
or
the
public;
(
4)
most
of
the
scientific
assessment
work
has
been
completed
while
meeting
other
Agency
requirements,
and
only
a
modest
additional
effort
will
be
needed
to
complete
the
review
and
documentation
for
IRIS.
Combined
with
specific
exposure
information,
the
data
in
IRIS
can
be
used
for
characterization
of
the
public
health
risks
of
a
given
chemical
in
a
given
situation,
that
can
then
lead
to
a
risk
management
decision
designed
to
protect
public
health.
2­
Propenoic
acid,
methyl
ester
(
CASRN
96­
33­
3)
is
listed
in
IRIS.
(
See
http://
www.
epa.
gov/
iris
for
additional
information)

Occupational
Safety
and
Health
Administration
(
OSHA)
­
OSHA
assigns
a
standard
which
"
most
adequately
assures,
to
the
extent
feasible,
on
the
basis
of
the
best
available
evidence,
that
no
employee
will
suffer
material
impairment
of
health
or
functional
capacity
even
if
such
employee
has
regular
exposure
to
the
hazard
dealt
with
by
such
standard
for
the
period
of
his
working
life"
(
29
U.
S.
C.
655(
b)).
This
standard
is
otherwise
known
as
a
Permissible
Exposure
Limit
(
PEL).
2­
Propenoic
acid,
methyl
ester
(
CASRN
96­
33­
3)
has
an
OSHA
PEL.

International
Agency
of
Research
on
Cancer
(
IARC)
­
IARC
has
identified
both
chemicals
as
not
classifiable
as
to
their
carcinogenicity
to
humans.

State
list
of
chemicals
of
concern
­
2­
Propenoic
acid,
butyl
ester
(
CASRN
141­
32­
2)
has
been
listed
by
one
or
more
states
on
at
least
one
state
list
of
chemicals
of
concern.

Inclusion
in
these
various
programs
indicates
that
there
are
hazard
concerns
associated
with
these
2Risk
is
composed
of
hazard
and
exposure.
In
order
to
screen
for
potential
risk
in
the
United
States,
both
hazard
data
and
exposure­
related
data
relative
to
United
States
situations
are
needed.
Exposure
is
based
upon
manufacturing,
processing,
and
use
scenarios,
all
of
which
change
over
time
as
technology
and
other
societal
effects
change.
The
changing
nature
of
exposure
scenarios
means
the
potential
risks
associated
with
a
chemical
can
also
change,
and
therefore
the
collection
of
exposure­
related
information
over
time
is
fundamental
to
identifying
potential
risks.
(
See
68
FR
848,
852
for
further
discussion)

3For
additional
information
on
uses
of
IUR
processing
and
use
information,
see
IURA
Data
Use
Plan,
located
in
EPA's
electronic
docket
OPPT­
2002­
0054,
item
number
0261.

4
See
the
introduction
to
the
EPA's
TRI
website
for
further
information,
at
http://
www.
epa.
gov/
tri/
whatis.
htm.

Page
4
of
9
chemicals.

Consideration
C:
The
information
needs
of
EPA,
other
federal
agencies,
tribes,
states,
and
local
governments,
as
well
as
members
of
the
public.

The
petition
review
group
found
that
both
chemicals
are
part
of
EPA's
HPV
Challenge
Program.
The
HPV
Challenge
Program
seeks
to
collect
and,
where
necessary,
develop
a
screening­
level
hazard
data
set
for
chemicals
produced
or
imported
in
large
quantities
in
the
United
States.
EPA
plans
to
screen
and,
as
needed,
further
assess
chemicals
included
under
the
HPV
Challenge
Program.
For
this
purpose,
the
IUR
processing
and
use
information
is
needed
by
EPA
to
put
the
hazard
data
into
context,
complementing
the
HPV
Challenge
Program
submission
by
providing
EPA
with
exposure­
related
information.
2
Reporting
of
IUR
processing
and
use
information
is
needed
at
least
once
and,
potentially,
periodically
thereafter
to
more
accurately
and
realistically
gauge
potential
exposure
and
provide
information
needed
for
screening,
assessing,
and
managing
exposures
and
risk.
Other
important
uses
of
the
reported
information,
even
for
low­
hazard
chemicals,
may
include
comparative
exposure
analyses,
identification
of
safer
substitutes,
or
pollution
prevention
investigations.
3
The
petition
review
group
also
found
that
both
chemicals
are
TRI
chemicals.
Chemicals
listed
on
TRI
are
of
proven
interest,
not
just
to
EPA,
but
to
the
public.
4
Information
reported
under
40
CFR
710.52(
c)(
4)
will
enhance
our
knowledge
of
the
types
of
processes
and
uses
that
produce
releases
of
and
exposures
to
these
toxic
chemicals.

Consideration
D:
The
availability
of
other
complementary
risk
screening
information.

The
petitions
referred
EPA
to
the
OECD
HPV
SIDS
reviews
of
these
chemicals,
but
did
not
identify
specific
information
within
those
documents
that
would
address
Consideration
D.
The
results
of
the
OECD
HPV
SIDS
reviews,
as
documented
in
the
SIAPs,
state
that
these
chemicals
have
properties
indicating
a
hazard
for
human
health
and
the
environment,
but
are
considered
low
priority
for
further
work
within
the
OECD
HPV
SIDS
program.
The
SIAPs
for
both
chemicals
indicate
that
in
2000,
United
States
TRI
reporting
indicated
that
the
majority
of
releases
reported
to
the
TRI
for
these
chemicals
is
to
air,
but
a
small
percentage
is
released
to
water.
The
SIAPs
suggest
that
countries
may
desire
to
investigate
exposure
scenarios
not
covered
by
the
OECD
5
The
OECD
HPV
SIDS
program,
while
it
is
not
United
States
based,
is
a
program
where
different
countries
are
combining
their
resources
to
investigate
at
least
the
hazards
associated
with
different
chemicals.
This
allows
all
of
the
countries
to
benefit
from
this
information.
The
United
States
can
use
information
collected
during
and
generated
by
the
OECD
HPV
SIDS
program
to
address
domestic
issues.

Page
5
of
9
HPV
SIDS
review.
With
the
collection
of
IUR
processing
and
use
data
for
these
chemicals,
the
United
States
will
be
able
to
identify
domestic
situations
by
combining
the
OECD
HPV
SIDS
program
hazard
data5
with
the
IUR
exposure­
related
information,
thereby
identifying
new
or
revised
exposure
scenarios.

As
these
chemicals
are
included
in
the
HPV
Challenge
Program,
additional
hazard
data
may
become
available.
However,
effective
risk
screening
and
risk
management
require
both
exposure
information
and
hazard
information.
The
availability
of
hazard
information
for
these
substances,
coupled
with
the
collection
of
IUR
processing
and
use
information
as
an
indicator
of
potential
exposure,
will
facilitate
a
more
effective
screening
of
these
and
other
substances
based
on
either
exposure
or
risk.
See
Consideration
E
below
for
further
discussion
of
the
IUR
exposure­
related
processing
and
use
information.

Consideration
E:
The
availability
of
comparable
processing
and
use
information.

The
petitions
referred
EPA
to
the
OECD
HPV
SIDS
review
documents
for
these
chemicals,
but
did
not
identify
specific
information
within
those
documents
that
addresses
Consideration
E.
The
SIAP
for
2­
propenoic
acid,
methyl
ester
(
CASRN
96­
33­
3)
(
dated
May
2003)
and
the
SIAP
for
2­
propenoic
acid,
butyl
ester
(
CASRN
141­
32­
2)
(
dated
October
2002)
contains
some
general
information
on
uses
and
global
production.
According
to
the
SIAPs,
both
chemicals
are
intermediates
manufactured
in
a
closed
system
and
used
to
make
polymers.
The
primary
use
of
2­
propenoic
acid,
methyl
ester
(
CASRN
96­
33­
3)
is
as
a
co­
monomer
in
the
preparation
of
polyacrylic
fibers,
in
the
manufacture
of
plastics,
coatings,
dispersions,
flocculants
and
varnishes
and
in
organic
synthesis;
exposure
during
processing
and
use
needs
to
be
mitigated
by
personal
protective
gear.
The
primary
use
of
2­
propenoic
acid,
butyl
ester
(
CASRN
141­
32­
2)
is
in
the
production
of
homo­
and
co­
polymers
with
other
monomers
to
produce
emulsion
polymers,
which
are
then
most
often
used
in
surface
coatings,
adhesives/
sealants
and
textiles.
Residual
monomer
concentrations
in
consumer
polymer
products
are
very
low
due
to
polymerization
and
therefore
releases
(
and
associated
consumer
exposures)
are
expected
to
be
negligible.

The
conclusion
of
the
OECD
HPV
SIDS
review
indicated
that
countries
may
wish
to
evaluate
exposure
scenarios
not
covered
by
the
report.
Although
the
United
States
sponsored
these
OECD
HPV
SIDS
program
evaluations,
the
petition
review
group
recognizes
that
since
exposure
scenarios
change
based
on
uses
and
available
technology,
information
quickly
becomes
outdated
and
of
limited
use.
Because
of
this,
the
relative
importance
of
each
use
may
change
or
new
uses
may
develop.
EPA
believes
tracking
these
changes
is
important,
especially
since
the
SIAP
indicated
that
these
chemicals
possesse
properties
indicating
a
hazard
for
human
health
and
the
environment.
The
IUR
provides
current
exposure­
related
processing
and
use
information
in
the
United
States
every
four
years.
This
facilitates
tracking
changes
in
use
patterns
and
the
Page
6
of
9
identification
of
new
exposure
scenarios,
which
is
an
important
component
of
risk
screening.

Additionally,
the
IUR
contains
some
exposure­
related
data
elements
not
provided
in
the
OECD
HPV
SIDS
submissions,
such
as
data
on
the
function
of
the
chemical
in
the
industrial
processing
and
use
category,
the
NAICS
code
associated
with
the
use,
and
the
number
of
potentially
exposed
workers
and
the
number
of
sites
associated
with
each
use.
For
commercial
and
consumer
uses,
the
IUR
collects
data
on
the
amount
of
the
chemical
in
various
use
categories,
the
concentration
of
the
chemical
in
the
use
category,
and
the
likelihood
of
inclusion
in
products
intended
for
children.
Furthermore,
IUR
information
is
updated
every
four
years,
is
quantitative,
and
is
specific
to
the
United
States.

Consideration
F:
Whether
the
potential
risks
for
the
chemical
substance
are
adequately
managed
by
EPA
or
another
agency
or
authority.

The
petitions
did
not
identify
or
discuss
any
risk
management
actions
taken
by
EPA
or
another
agency
or
authority
with
respect
to
the
petitioned
chemicals.
The
petitions
did
not
explain
why
the
downstream
processing
and
use
information
should
be
of
low
current
interest
in
light
of
any
such
risk
management
actions.

Other
Considerations/
Notes:

The
SIAPs
noted
conclusions
of
"
low
priority
for
further
work"
under
the
OECD
HPV
SIDS
program,
but
noted
that
the
chemicals
possessed
properties
indicating
a
hazard
for
human
health
and
the
environment.
A
designation
of
low
priority
for
further
work
within
the
OECD
HPV
SIDS
program
means
that
no
further
hazard
testing
is
needed
to
meet
the
purposes
of
the
OECD
HPV
SIDS
program
at
the
time
the
review
was
completed.
These
judgements,
however,
do
not
determine
the
approach
that
an
individual
OECD
member
country
must
take
in
considering
such
a
chemical.
Rather,
the
OECD
HPV
SIDS
program
assessment
is
seen
as
a
starting
point
for
assessment
in
countries.
In
the
United
States
case,
it
is
a
starting
point
for
a
screening­
level
risk
assessment,
for
which
IUR
processing
and
use
information
provides
screening­
level
exposure
information.
In
the
past
there
have
been
a
number
of
chemicals
identified
by
the
OECD
HPV
SIDS
program
as
a
"
low
priority
for
further
work,"
but
for
which
EPA
wanted
to
make
a
confirmatory
priority
judgement
based
on
risk
 
i.
e.,
screening­
level
hazard
information
based
on
the
OECD
HPV
SIDS
program
work
plus
screening­
level
exposure
information
based
on
the
United
States
situation.
Page
7
of
9
Table
1:
Chemical
Names
Used
in
Petitions
that
Differ
from
TSCA
Inventory
Chemical
Names
CASRN
TSCA
Inventory
Chemical
Name
Chemical
Name
Used
in
Petitions
96­
33­
3
2­
propenoic
acid,
methyl
ester
Methyl
Acrylate
141­
32­
2
2­
propenoic
acid,
butyl
ester
n­
Butyl
Acrylate
Cited
Reference:
1)
SIAPs
for
2­
propenoic
acid,
methyl
ester
(
CASRN
96­
33­
3)(
May
2003)
and
2­
propenoic
acid,
butyl
ester
(
CASRN
141­
32­
2)
(
October
2002).
Available
on
the
web
at
http://
cs3­
hq.
oecd.
org/
scripts/
hpv/
NewSIDS.
asp
Sources
Searched:
(
Note:
These
sources
are
typically
searched
or
reviewed
to
gather
information
presented
in
the
petition
review
report.)

American
Conference
of
Governmental
Industrial
Hygienists
(
ACGIH)
Threshold
Limit
Values
(
TLV­
TWA).
2003.
ACGIH,
Cincinnati
OH.
pp.
12­
61.

Agency
for
Toxic
Substances
and
Disease
Registry
(
ATSDR)
ToxFAQsTM
(
Frequently
asked
questions
about
contaminants
found
at
hazardous
waste
sites).
Available
at
http://
www.
atsdr.
cdc.
gov/
toxfaq.
html
California
Air
Resources
Board
List
of
Toxic
Air
Contaminant
Fact
Sheets,
available
at
http://
arbis.
arb.
ca.
gov/
toxics/
tac/
toctbl.
htm
California
EPA,
Safe
Drinking
Water
and
Toxic
Enforcement
Act
of
1986:
List
of
chemicals
known
to
the
State
to
cause
cancer
or
reproductive
toxicity.
Listing
as
of
Nov.
14,
2003.
Available
at
http://
www.
oehha.
ca.
gov/
prop65/
CRNR_
notices/
list_
changes/
111403lsta.
html
International
Agency
of
Research
on
Cancer
(
IARC)
Overall
Evaluations
of
Carcinogenicity
to
Humans.
Available
at
http://
monographs.
iarc.
fr/
monoeval/
crthall.
html
Interagency
Testing
Committee
(
ITC)
Priority
Testing
List.
Available
at
http://
tsca­
itc.
syrres.
com/
Chemicals/

National
Advisory
Committee
Acute
Exposure
Guideline
Levels
(
AEGLs).
Available
at
http://
www.
epa.
gov/
oppt/
aegl/
index.
htm
Organisation
for
Economic
Cooperation
and
Development
(
OECD)
Integrated
HPV
Database,
http://
cs3­
hq.
oecd.
org/
scripts/
hpv/
index.
asp
United
Nations
Environment
Programme
(
UNEP)
persistent
organic
pollutants
(
POPs),
available
at
http://
www.
chem.
unep.
ch/
pops/
default.
html
United
Nations
Environment
Programme
(
UNEP)
Ozone
Secretariat,
Summary
Control
Measures,
available
at
http://
www.
unep.
org/
ozone/
Treaties_
and_
Ratification/
2B_
montreal_
protocol.
asp
U.
S.
EPA
Clean
Air
Act
(
CAA)
Hazardous
Air
Pollutants
(
HAPs).
Available
in
the
Clean
Air
Act,
section
112(
b),
available
at
http://
www.
epa.
gov/
air/
caa/
caa112.
txt
U.
S.
EPA.
Emergency
Planning
and
Community
Right­
to­
Know
Act
Section
313,
List
of
Toxic
Chemicals.
2001.
Office
of
Environmental
Information,
EPA
260­
B­
01­
001,
available
at
http://
www.
epa.
gov/
tri/
chemical/
chemlist2001.
pdf
U.
S.
EPA
HPV
(
High
Production
Volume)
Challenge
Program
and
Voluntary
Children's
Chemical
Evaluation
Program
(
VCCEP)
Web
sites
under
the
EPA
Chemical
Right­
to­
Know
Initiative,
http://
www.
epa.
gov/
chemrtk
Page
8
of
9
U.
S.
EPA
Integrated
Risk
Information
System
(
IRIS)
Substance
List.
Available
at
http://
www.
epa.
gov/
iris/
subst/
index.
html
U.
S.
EPA.
National
Recommended
Water
Quality
Criteria:
2002.
Office
of
Water.
EPA­
822­
R­
02­
047.
Available
at
http://
www.
epa.
gov/
waterscience/
pc/
revcom.
pdf
U.
S.
EPA.
2004
Edition
of
the
Drinking
Water
Standards
and
Health
Advisories.
Office
of
Water.
EPA­
822­
R­
04­
005.
Available
at
http://
www.
epa.
gov/
waterscience/
drinking/
standards/
dwstandards.
pdf
U.
S.
EPA
Substance
Registry
System
(
SRS).
Available
at
http://
www.
epa.
gov/
srs/

U.
S.
Occupational
Safety
and
Health
Administration
(
OSHA)
Permissible
Exposure
Limits
(
PELs),
available
at
http://
www.
osha.
gov/
SLTC/
pel/
index.
html
List
of
Acronyms
Page
9
of
9
ACGIH
American
Conference
of
Governmental
Industrial
Hygienists
AEGL
Acute
Exposure
Guideline
Level
ARB
Air
Resources
Board
ATSDR
Agency
for
Toxic
Substances
and
Disease
Registry
CAA
Clean
Air
Act
CASRN
Chemical
Abstract
Service
Registry
Number
CICAD
Concise
International
Chemical
Assessment
Document
CPSC
Consumer
Product
Safety
Commission
EHC
Environmental
Health
Criteria
EPA
Environmental
Protection
Agency
EU
European
Union
FDA
Food
and
Drug
Administration
FFDCA
Federal
Food,
Drug,
and
Cosmetic
Act
FIFRA
Federal
Insecticide,
Fungicide,
and
Rodenticide
Act
GRAS
Generally
Recognized
as
Safe
HAP
Hazardous
Air
Pollutant
HPV
High
Production
Volume
HSDB
Hazardous
Substances
Databank
IARC
International
Agency
of
Research
on
Cancer
ICCA
International
Council
of
Chemical
Associations
IFCS
International
Forum
on
Chemical
Safety
IPCS
International
Programme
on
Chemical
Safety
IRIS
Integrated
Risk
Information
System
IRPTC
International
Register
of
Potentially
Toxic
Chemicals
ITC
Interagency
Testing
Committee
IUCLID
International
Uniform
Chemical
Information
Database
IUR
Inventory
Update
Reporting
Rule
IURA
Inventory
Update
Reporting
Rule
Amendment
NAICS
North
American
Industry
Classification
System
NIOSH
National
Institute
for
Occupational
Safety
and
Health
OECD
Organisation
for
Economic
Cooperation
and
Development
OECD
HPV
SIDS
or
OECD
HPV
SIDS
program
OECD/
SIDS
HPV
Chemicals
Programme
OPP
Office
of
Pesticide
Programs
OPPT
Office
of
Pollution
Prevention
and
Toxics
OSHA
Occupational
Safety
and
Health
Administration
PEL
Permissible
Exposure
Limit
POP
Persistent
Organic
Pollutant
SIAM
SIDS
Initial
Assessment
Meeting
SIAP
SIDS
Initial
Assessment
Profile
SIAR
SIDS
Initial
Assessment
Report
SIDS
Screening
Information
Data
Set
SRS
Substance
Registry
System
TLV­
TWA
Threshold
Limit
Value
Time­
Weighted
Average
TRI
Toxics
Release
Inventory
TSCA
Toxic
Substances
Control
Act
UNEP
United
Nations
Environment
Programme
VCCEP
Voluntary
Children's
Chemical
Evaluation
Program
