MADEX Twin

Insecticidal Virus

Sublabel A: Agricultural Use 

Sublabel B: Residential Use

Active Ingredient*:

Cydia pomonella granulovirus isolate V22	0.06%

Other Ingredients:	99.94%

Total:	100.00%

*Contains a minimum of 3x1013 viral occlusion bodies per liter.

KEEP OUT OF REACH OF CHILDREN

CAUTION

EPA Reg. No.: 69553-

EPA Est. No.: 

Manufactured by: 	Andermatt Biocontrol AG

Stahlermatten 6

CH-6146 Grossdietwil

Switzerland

SUBLABEL A: Agricultural Use

MADEX Twin

Biological Insecticide for Control of the Codling Moth and Oriental
Fruit Moth

Active Ingredient*:

Cydia pomonella granulovirus isolate V22	0.06%

Other Ingredients:	99.94%

Total:	100.00%

*Contains a minimum of 3x1013 viral occlusion bodies per liter.

KEEP OUT OF REACH OF CHILDREN

CAUTION

SEE SIDE/INSIDE PANEL FOR ADDITIONAL PRECAUTIONARY STATEMENTS

Net Contents: 

Lot No.:

EPA Reg. No. 69553-

EPA Est. No. 

Manufactured by: 	Andermatt Biocontrol AG

Stahlermatten 6

CH-6146 Grossdietwil

Switzerland

PRECAUTIONARY STATEMENTS

Hazards To Humans and Domestic Animals

CAUTION. Causes moderate eye and skin irritation. Avoid contact with
skin, eyes or clothing. Wash thoroughly with soap and water after
handling and before eating, drinking, chewing gum, using tobacco, or
using the toilet. Remove and wash contaminated clothing before reuse.

FIRST AID



If in eyes:	Hold eye open and rinse slowly and gently with water for
15-20 minutes. Remove contact lenses, if present, after the first 5
minutes, then continue rinsing.

Call a poison control center or doctor for treatment advice.



If on skin:	Take off contaminated clothing.

Rinse skin immediately with plenty of water for 15-20 minutes.

Call a poison control center or doctor for treatment advice.

HOT LINE NUMBER

Have the product container or label with you when calling a poison
control center or doctor, or going for treatment. You may also contact
the National Poison Control Hotline at 1-800-222-1222 for emergency
medical treatment information.



PERSONAL PROTECTIVE EQUIPMENT (PPE)

Applicators and other handlers must wear: 

long-sleeved shirt and long pants

waterproof gloves

shoes plus socks

Follow manufacturers’ instructions for cleaning/maintaining PPE. If no
such instructions for washables exist, use detergent and hot water. Keep
and wash PPE separately from other laundry.

Mixers/loaders and applicators must wear a dust/mist filtering
respirator meeting NIOSH standards of at least N-95, R-95 or P-95.
Repeated exposures to high concentrations of microbial proteins can
cause allergic sensitization.

Engineering Controls

When handlers use closed systems or enclosed cabs in a manner that meet
the requirements listed in the Worker Protection Standard (WPS) for
agricultural pesticides [40 CFR 170.240(d)(4-6)], the handler PPE
requirements may be reduced or modified as specified in the WPS.

IMPORTANT: When reduced PPE is worn because a closed system is being
used, handlers must provide all PPE specified above for “applicators
and other handlers” and have such PPE immediately available for use in
an emergency, such as a spill or equipment breakdown.

Environmental Hazards

For terrestrial uses: Do not apply directly to water, or to areas where
surface water is present or to intertidal areas below the mean high
water mark. Do not contaminate water when cleaning equipment or
disposing of equipment wash waters or rinsate.

DIRECTIONS FOR USE

It is a violation of Federal law to use this product in a manner
inconsistent with its labeling.

Do not apply this product in a way that will contact workers or other
persons either directly or through drift. Only protected handlers may be
in the area during application. For any requirements specific to your
State or Tribe, consult the State or Tribal agency responsible for
pesticide regulation.

Agricultural Use Requirements

Use this product only in accordance with its labeling and with the
Worker Protection Standard, 40 CFR Part 170. This Standard contains
requirements for the protection of agricultural workers on farms,
forests, nurseries and greenhouses, and handlers of agricultural
pesticides. It contains requirements for training, decontamination,
notification, and emergency assistance. It also contains specific
instructions and exceptions pertaining to the statements on this label
about personal protective equipment (PPE), and restricted entry
intervals (REI). The requirements in this box only apply to uses of this
product that are covered by the Worker Protection Standard. 

Do not enter or allow worker entry into treated areas during the
restricted entry interval (REI) of 4 hours unless wearing appropriate
PPE.

PPE required for early entry to treated areas that is permitted under
the Worker Protection Standard and that involves contact with anything
that has been treated, such as plants, soil or water, is:

• Coveralls

• Waterproof gloves

• Shoes plus socks

GENERAL INFORMATION

MADEX Twin acts very specifically against larvae of the apple codling
moth, Cydia pomonella, and the Oriental fruit moth, Grapholita molesta,
as a pre-harvest biological insecticide on pome and stone fruit trees
including apple, quince, pear, peach, nectarine, apricot, plum, cherry,
walnut, almond, pluot, and aprium. After ingestion by the larva, the
virus multiplies within the cells of the host insect causing a fatal
infection. Rapid virus multiplication within the host cells results in
cell destruction and death of the organism, typically within 3-7 days.

Start spraying shortly before larvae hatch from the eggs and before the
larvae feed their way into the fruit. In general, one to two sprays per
generation are generally sufficient. Due to unfavorable weather
conditions, flight, egg laying, and hatching may extend over a longer
period of time and up to 6 applications may be needed.

Frequent applications at low rates may be more effective than one or two
applications at high rates.

Use Restriction

Do not apply this product through any type of irrigation system.

MIXING AND APPLICATION INSTRUCTIONS

Mix MADEX Twin with water and apply as a spray to fruit and foliage of
trees in orchards and nurseries. Use water at or near neutral pH (7).

CROP	RATE	COMMENTS

Pome and Stone fruit trees including apple, quince, pear, peach,
nectarine, apricot, plum, prunes cherry, walnut, almond, pluot, and
aprium 	0.5 - 3.0 fluid ounces per acre, depending on pest pressure and
application frequency.	Select a spray volume appropriate to tree size
and density of foliage. For small trees use 50-100 gallons of water per
acre. Larger trees with denser canopies require 100-200 gallons per
acre.

Consult your local Cooperative Extension Service if you need advice
about how to attain good spray coverage in your orchard.

Make at least two (2) applications of MADEX Twin per codling moth or
Oriental fruit moth larval generation. Target small larvae early in
their life cycle. Repeat as necessary to maintain control. MADEX Twin
breaks down under direct exposure to sunlight. If moths are still flying
and laying eggs, reapply after 6-8 sunny days (counting 2 partially
sunny days as 1 sunny day).





MADEX Twin can be applied up to and including the day of harvest.

STORAGE AND DISPOSAL

Do not contaminate water, food or feed by storage and disposal.

PESTICIDE STORAGE:

Store this product in original sealed container in a cool, dry place
inaccessible to children and pets. Store at temperatures below 41°F
(5°C). Bioactivity may be impaired by storage above 86°F (30°C).
Storing the product under cold or freezing temperatures will extend its
shelf life.

PESTICIDE DISPOSAL:

To avoid wastes, use all material in this container by application
according to label directions. If wastes cannot be avoided, offer
remaining product to a waste disposal facility or pesticide disposal
program (often such programs are run by state or local governments or by
industry).

CONTAINER HANDLING:

Nonrefillable container. Do not reuse or refill this container. Triple
rinse container (or equivalent) promptly after emptying. Triple rinse as
follows: Empty the remaining contents into application equipment or a
mix tank and drain 10 seconds after the flow begins to drip. Fill the
container 1/4 full with water and recap. Shake for 10 seconds. Pour
rinsate into application equipment or a mix tank or store rinsate for
later use or disposal. Drain for 10 seconds after the flow begins to
drip. Repeat this procedure two more times. Then offer for recycling if
available or puncture and dispose of in a sanitary landfill, or by
incineration. Do not burn, unless allowed by State and local ordinances.



WARRANTY

Andermatt Biocontrol AG warrants that the material contained herein
conforms to the description on the label and is reasonably fit for the
purposes referred to in the directions for use. Timing and method of
application, weather, watering practices, nature of soil, the insect
problem, condition of the crop, incompatibility with other chemicals not
specifically recommended and other influencing factors in the use of
this product are beyond the control of the seller. To the extent
consistent with applicable law, buyer assumes all risks of use, storage
or handling of this material not in strict accordance with directions
given herein. To the extent consistent with applicable law, NO OTHER
EXPRESS OR IMPLIED WARRANTY OF THE FITNESS OR MERCHANTABILITY IS MADE.

Sublabel B: Residential Use

MADEX Twin

Biological Insecticide for Control of the Codling Moth and Oriental
Fruit Moth

Active Ingredient*:

Cydia pomonella granulovirus isolate V22	0.06%

Other Ingredients:	99.94%

Total:	100.00%

*Contains a minimum of 3x1013 viral occlusion bodies per liter.

KEEP OUT OF REACH OF CHILDREN

CAUTION

SEE SIDE/INSIDE PANEL FOR ADDITIONAL PRECAUTIONARY STATEMENTS

Net Contents: 

Lot No.:

EPA Reg. No. 69553-

EPA Est. No. 

Manufactured by: 	Andermatt Biocontrol AG

Stahlermatten 6

CH-6146 Grossdietwil

Switzerland

PRECAUTIONARY STATEMENTS

Hazards To Humans and Domestic Animals

CAUTION. Causes moderate eye and skin irritation. Avoid contact with
skin, eyes or clothing. Wash thoroughly with soap and water after
handling and before eating, drinking, chewing gum, using tobacco, or
using the toilet. Remove and wash contaminated clothing before reuse.
When mixing and applying this product, wear a dust mask. Repeated
exposures to high concentrations of microbial proteins can cause
allergic sensitization.

FIRST AID



If in eyes:	Hold eye open and rinse slowly and gently with water for
15-20 minutes. Remove contact lenses, if present, after the first 5
minutes, then continue rinsing.

Call a poison control center or doctor for treatment advice.



If on skin:	Take off contaminated clothing.

Rinse skin immediately with plenty of water for 15-20 minutes.

Call a poison control center or doctor for treatment advice.

HOT LINE NUMBER

Have the product container or label with you when calling a poison
control center or doctor, or going for treatment. You may also contact
the National Poison Control Hotline at 1-800-222-1222 for emergency
medical treatment information.



ENVIRONMENTAL HAZARDS

To protect the environment, do not allow pesticide to enter or run off
into storm drains, drainage ditches, gutters or surface waters. Applying
this product in calm weather when rain is not predicted for the next 24
hours will help to ensure that wind or rain does not blow or wash
pesticide off the treatment area. Rinsing application equipment over the
treated area will help avoid run off to water bodies or drainage
systems.

DIRECTIONS FOR USE

It is a violation of Federal law to use this product in a manner
inconsistent with its labeling. 

GENERAL INFORMATION

MADEX Twin acts very specifically against larvae of the apple codling
moth, Cydia pomonella, and the Oriental fruit moth, Grapholita molesta,
as a pre-harvest biological insecticide on pome and stone fruit trees
including apple, quince, pear, peach, nectarine, apricot, plum, cherry,
walnut, almond, pluot, and aprium. After ingestion by the larva, the
virus multiplies within the cells of the host insect causing a fatal
infection. Rapid virus multiplication within the host cells results in
cell destruction and death of the organism, typically within 3-7 days. 

Start spraying shortly before larvae hatch from the eggs and before the
larvae feed their way into the fruit. In general, one to two sprays per
generation are generally sufficient. Due to unfavorable weather
conditions, flight, egg laying, and hatching may extend over a longer
period of time and up to 6 applications may be needed.

Use Restrictions

For use only on pome and stone fruit trees in residential settings. Not
for use on trees or fruit grown for sale or other commercial use.

MIXING AND APPLICATION INSTRUCTIONS

MADEX Twin must be mixed with water and applied as a spray to the fruit
and foliage of pome and stone fruit trees (apple, quince, pear, peach,
nectarine, apricot, plum, cherry, walnut, and almond). 

Mix 1/2 teaspoon of MADEX Twin per 5 gallons of water and apply directly
to each tree using a hand pump sprayer or other suitable spray
equipment. Spray a sufficient volume to thoroughly wet all leaves and
fruit with minimal run-off or dripping. 

Apply MADEX Twin first in late spring or early summer, when eggs of the
first generation of codling moth or Oriental fruit moth begin to hatch.
Apply MADEX Twin at least twice during each larval generation. When pest
pressure persists, make additional applications of MADEX Twin in mid- to
late summer. Consult your local Cooperative Extension Service for more
information about the best timing of codling moth and Oriental fruit
moth sprays.

MADEX Twin breaks down under direct exposure to-sunlight. If moths are
still flying and laying eggs, reapply after 6-8 sunny days (counting 2
partially sunny days as 1 sunny day).

STORAGE AND DISPOSAL

Do not contaminate water, food, or feed by storage and disposal.

PESTICIDE STORAGE:

Keep in original container. Store away from direct sunlight, feed, or
foodstuffs. Keep container tightly sealed when not in use. Store at
temperatures below 41°F (5°C). Bioactivity may be impaired by storage
above 86°F (30°C). Storing the product under cold or freezing
temperatures will extend its shelf life.

PESTICIDE DISPOSAL AND CONTAINER HANDLING:

Non-refillable container. Do not reuse or refill container.

If empty:

Place in trash or offer for recycling, if available.

If partly filled:

Call your local solid waste agency for disposal instructions. Never
place unused product down any indoor or outdoor drain.





WARRANTY

Andermatt Biocontrol AG warrants that the material contained herein
conforms to the description on the label and is reasonably fit for the
purposes referred to in the directions for use. Timing and method of
application, weather, watering practices, nature of soil, the insect
problem, condition of the crop, incompatibility with other chemicals not
specifically recommended and other influencing factors in the use of
this product are beyond the control of the seller. To the extent
consistent with applicable law, buyer assumes all risks of use, storage
or handling of this material not in strict accordance with directions
given herein. To the extent consistent with applicable law, NO OTHER
EXPRESS OR IMPLIED WARRANTY OF THE FITNESS OR MERCHANTABILITY IS MADE.

Master Label

Page   PAGE  8  of   NUMPAGES   10 

Dec. 4, 2012

USER SAFETY RECOMMENDATIONS

Users should wash hands before eating, drinking, chewing gum, using
tobacco or using the toilet. Remove PPE immediately after handling this
product. Wash the outside of gloves before removing. As soon as
possible, wash thoroughly and change into clean clothing.

