                                 FINAL AGENDA
                     FIFRA SCIENTIFIC ADVISORY PANEL (SAP)
                                 OPEN MEETING
                                May 24-26, 2011
                                       
              FIFRA SAP WEB SITE http://www.epa.gov/scipoly/sap/
                     OPP Docket Telephone: (703) 305-5805
                     Docket Number: EPA-HQ- OPP-2011-0284
                                       
                     U.S. Environmental Protection Agency
                        Conference Center - Lobby Level
                        One Potomac Yard (South Bldg.)
                  2777 S. Crystal Drive, Arlington, VA 22202
                                       
Integrated Approaches to Testing and Assessment Strategy:  Use of New Computational and Molecular Tools 
                                       
Please note that all times are approximate (see note at end of Agenda).
                                       
Tuesday, May 24, 2011

8:30 A.M. 	Opening of Meeting and Administrative Procedures
            Dr. Fred Jenkins, Designated Federal Official, Office of Science Coordination and Policy, EPA

8:35 A.M. 	Introduction and Identification of Panel Members
      Dr. Kenneth Portier, Chair, FIFRA Scientific Advisory Panel

8:40 A.M. 	Welcome and Opening Remarks
      Dr. Steven Bradbury, Director, Office of Pesticide Programs (OPP), EPA

9:00 A.M. 	OPP's Vision for an Integrated Approach to Testing and Assessment
            Dr. John (Jack) R. Fowle III, Deputy Director, Health Effects Division, OPP, EPA

      Partnership with ORD to Build a Scientific Foundation for the Vision 

9:45 A.M.	EPA's Chemical Safety for Sustainability Research Program
            Dr. Elaine Francis, National Program Director for Pesticides and Toxics Research, ORD, EPA

10:30 A.M.	BREAK




10:40 A.M.	Building Libraries of Adverse Outcome Pathways
            Dr. Daniel Villeneuve, Aquatic Toxicologist, Toxic Effects Characterization Research Branch, MED, NHEERL, ORD, EPA

12:00 P.M.  	LUNCH

1:15 P.M.	Building Knowledgebases and Decision Support Tools
            Dr. Patricia Schmieder, Chief Molecular and Cellular Mechanisms Research Branch, MED, NHEERL, ORD, EPA

      Partnership with Stakeholders

2:30 P.M.  	Partnerships with Stakeholders  -  PPDC Workgroup 
            Kristie Sullivan, MPH, Scientific and Policy Advisor of
Physicians Committee for Responsible Medicine

3: 15 P.M. 	BREAK

Case Studies

3:30 P.M. 	Introduction to Integration of Toxicogenomic Technology to Inform Risk Assessment; A Case Study: Propiconazole
      Ms. Nancy McCarroll, Geneticist, RAB VI, Health Effects Division, OPP, EPA

4:05 P.M. 	Integration of Toxicogenomic Technology to Inform Risk Assessment; A Case Study: Propiconazole
            Dr. Stephen Nesnow, Senior Research Scientist, Integrated Systems Toxicology Division, NHEERL, ORD, EPA

5:30 P.M. 	ADJOURN


Wednesday, May 25, 2011

8:30 A.M. 	Opening of Meeting and Administrative Procedures
            Dr. Fred Jenkins, Designated Federal Official, Office of Science Coordination and Policy, EPA

8:35 A.M. 	Introduction and Identification of Panel Members
      Dr. Kenneth Portier, Chair, FIFRA Scientific Advisory Panel

8:45 A.M. 	Introduction to Use of Adverse Outcome Pathway (AOP) to Inform Risk Assessment: Triclosan Case Study
            Dr. Timothy F. McMahon, Senior Toxicologist, Antimicrobial Division, OPP, EPA

9:15 A.M. 	Research approach - Mapping the Thryroid AOP for Neurodevelopmental Effects: Triclosan Case Study
            Dr. Kevin Crofton, Integrated Systems Toxicology Division, NHEERL, ORD, EPA

10:15 A.M. 	Research approach  -  Experimental Studies:  Triclosan Case Study
            Dr. Tammy Stoker, Research Biologist, Endocrine Toxicology Branch, Toxicity Assessment Division, NHEERL, ORD, EPA  

11:15 P.M. 	BREAK

11:25 P.M.     Public Comments

12:00 P.M.	 LUNCH

1:10 P.M.	Public Comments

3:10 P.M.	BREAK 
      
3:20 P.M.	Presentation of Charge Questions on OPP's Strategic Vision
      Dr. Jennifer McLain, Deputy Director, Antimicrobial Division, OPP, EPA

3:30 P.M. 	Discussion of Charge Questions

5:30 P.M. 	ADJOURN


Thursday, May 26, 2011

8:45 A.M. 	Opening of Meeting and Administrative Procedures
            Dr. Fred Jenkins, Designated Federal Official, Office of Science Coordination and Policy, EPA

8:50 A.M. 	Introduction and Identification of Panel Members
      Dr. Kenneth Portier, Chair, FIFRA Scientific Advisory Panel

9:00 A.M. 	Discussion of Charge Questions (Cont'd for OPP's Strategic Vision)

10:00 A.M.	BREAK

10:10 A.M.	Presentation of Charge Questions for Case Study I
      Dr. Jennifer McLain, Deputy Director, Antimicrobials Division, OPP
            
10:20 A.M. 	Discussion of Charge Questions

12:00 A.M. 	LUNCH

1:15 P.M. 	Discussion of Charge Questions (Cont'd for Case Study 1)

2:15 P.M.	BREAK		

2:25 P.M.	Presentation of Charge Questions for Case Study II
            Dr. Timothy F. McMahon, Senior Toxiciologist, Antimicrobial Division, OPP, EPA

2:35 P.M.	Discussion of Charge Questions

5:30 P.M. 	ADOURN






Please be advised that agenda times are approximate; when the discussion for one topic is completed, discussions for the next topic will begin. For further information, please contact the Designated Federal Official for this meeting, Dr. Fred Jenkins, via telephone: (202) 564-3327; fax: (202) 564-8382; or email: jenkins.fred@epa.gov
