List of References Provided by One Panel

Route-to-Route Extrapolation

Pauluhn, J. (2003). Issues of dosimetry in inhalation toxicity. Tox.
Letters 140-141: 229-238. [refer to Section 3, pages 235-237 and Figures
4 and 5]. [abstract available from:   
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TCR-487K2N9-G
&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_searchS
trId=1100730775&_rerunOrigin=google&_acct=C000050221&_version=1&_urlVers
ion=0&_userid=10&md5=fd5d141b338e32473b953d6f876a99c0]

Duration Adjustments

Jarabek, A.M. (1995a). Consideration of Temporal Toxicity Challenges
Current Default Assumptions. Inhal. Toxicol. 7: 927-46. [abstract
available from:
http://www.informaworld.com/smpp/1962735530-65235248/content~db=all~cont
ent=a784797894]

Threshold of Toxicological Concern/Threshold of Regulation Approaches

Drew, R. and Frangos, J. (2007). The Concentration of No Toxicological
Concern (CoNTC): A Risk Assessment Screening Tool for Air Toxics. J.
Tox. Env. Health, Part A 70: 1584-1593. [This article provides an
excellent summary of the history of these types of approaches and shows
how these approaches have been used in a regulatory setting] [abstract
available from: 
http://www.informaworld.com/smpp/content~content=a781628584~db=all~order
=page]

Time Extrapolation Factors

Kalberlah, F., Fost, U. and Schneider, K. (2002). Time Extrapolation and
Interspecies Extrapolation for Locally Acting Substances in Case of
Limited Toxicological Data. Ann. Occup. Hyg. 46: 175-185. [abstract
available from:  http://www.ncbi.nlm.nih.gov/pubmed/12074027]

Kramer, H.J., Ham, W.A. van den, Slob, W. And Pieters, M.N. (1996).
Conversion Factors Estimating Indicative Chronic
No-Observed-Adverse-Effect Levels from Short-Term Toxicity Data. Reg.
Tox. Pharm. 23: 249-255. [This paper is for oral exposure, but it
presents the mathematic approaches/equations needed to calculate the 95
percentile as well as the tolerance limits on the 95 percentile for a
log-normal distribution] [abstract available from: 
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WPT-45N457K-3
F&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_search
StrId=1100728013&_rerunOrigin=google&_acct=C000050221&_version=1&_urlVer
sion=0&_userid=10&md5=043f838fd5fff026058adad8f59d3e58]

Kramer, H.J., Ham, W.A. van den, Slob, W. And Pieters, M.N. (1995).
Derivation of Conversion Factors to Estimate an Indicative Chronic NOAEL
from Short-Term Toxicity Data. RIVM Report 620110001. Bilthoven – the
Netherlands.   HYPERLINK
"http://www.rivm.nl/bibliotheek/rapporten/620110001.html" 
http://www.rivm.nl/bibliotheek/rapporten/620110001.html 

Pieters, M.N., Kramer, H.J., and Slob, W. (1997). The Applicability of
Conversion Factors for Indicative Standard Setting. RIVM report
620110003. Bilthoven – the Netherlands.   HYPERLINK
"http://www.rivm.nl/bibliotheek/rapporten/620110003.html" 
http://www.rivm.nl/bibliotheek/rapporten/620110003.html 

