  SEQ CHAPTER \h \r 1 

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C.  20460

OFFICE OF              

PREVENTION, PESTICIDES

AND TOXIC SUBSTANCES 

MEMORANDUM

DATE:  	Jan 14, 2010

SUBJECT:	Acetamiprid.  Revised Acute and Chronic Dietary Exposure
Assessments (Food and Drinking Water) to Support Section 3 Registration
of Uses on Clover, Small Vine Climbing Fruits, except Fuzzy Kiwifruit,
Subgroup 13-07F, Greenhouse Grown Tomatoes and Tea. 

PC Code:  099050	DP Barcode:  D372890

Decision No.:  408298	Registration Nos.:  8033-23,  8033-36, 8033-94

Petition No.:  9E7544	Regulatory Action:  Amended Section 3

Risk Assessment Type:  Single Chemical Aggregate, Dietary	Case No.:  N/A

TXR No.:  N/A	CAS No.:  135410-20-7

MRID Nos.:  N/A	40 CFR:  §180.578



REVIEWER:	Dennis McNeilly, Chemist

Registration Action Branch 2

Health Effects Division (7509P)

THROUGH:	Julie Van Alstine, MPH, Environmental Health Scientist

Douglas Dotson, Ph.D., Chemist

Dietary Exposure Science Advisory Council (DESAC)

Health Effects Division (7509P)

TO:			Laura Nollen, Risk Manager Reviewer

			Barbara Madden, Team Leader (RM Team 5)

			RIMUERB/Registration Division (RD) (7505P)

Executive Summary

 (DEEM-FCID™, Version 2.03) which uses food consumption data from the
USDA’s Continuing Surveys of Food Intakes by Individuals (CSFII,
1994-1996 and 1998).  Analyses were previously performed to support the
requested Section 3 registration of acetamiprid on clover, small vine
climbing fruits, except kiwifruit, subgroup 13-07F (amending grape use);
green house grown tomatoes; and tea (D369019, D. McNeilly, 12/1/2009). 
RD has requested that HED redo the analyses using 100% percent crop
treated for all amended commodities, i.e., grapes and other subgroup
13-07F commodities, and tomatoes. 

Acute Dietary (Food and Drinking Water) Exposure Results and
Characterization

The probabilistic acute dietary exposure assessment included tolerance
level residues, anticipated residues from field residue trials,
processing factors, maximum percent crop treated (%CT) estimates (for
existing uses only) generated by the Biological and Economic Analysis
Division (BEAD), and the modeled peak concentration of acetamiprid
residues in surface and groundwater water sources of drinking water. 
Although the acute assessment has been refined, the resulting exposure
estimates are still considered to be conservative since field trial data
were the basis for the anticipated residues, and because a conservative
drinking water model (FIRST) was used to estimate residues in drinking
water.

Acute dietary exposure estimates at the 99.9th percentile are below
HED’s level of concern for the general US population and all other
population subgroups.  For the US population, the estimated exposure of
0.024 mg/kg/day corresponds to 24% aPAD; for children 1-2 years old, the
estimated exposure of 0.043 mg/kg/day corresponds to an acute dietary
risk of 43% aPAD.

 

Chronic Dietary (Food and Drinking Water) Exposure Results and
Characterization

For the chronic analysis, tolerance-level residues were assumed for all
food commodities with existing and proposed acetamiprid tolerances. 
Percent crop treated was used for many commodities as detailed in Table
3.  The chronic analysis also included the modeled surface water annual
average residue in drinking water.  Even though %CT information was used
in the chronic analysis, the exposure and risk estimates are still
conservative since tolerance level residues were used, because 100 %CT
was assumed for crops where percent crop treated information was not
available, and because a conservative drinking water model (FIRST) was
used.

Chronic dietary exposure to acetamiprid, including existing and proposed
uses, is below HED’s level of concern for the US population and all
other population subgroups.  For the general US population, an estimated
exposure of 0.0028 mg/kg/day corresponds to 4% of the chronic population
adjusted dose (cPAD); children 1-2 years old was the highest exposed
population subgroup, with an estimate of 0.010 mg/kg/day, or 15% cPAD. 
Risks for all population subgroups are less than 100% cPAD, and are not
of concern.

I.	Introduction

Dietary risk assessment incorporates both exposure and toxicity of a
given pesticide.  For acute and chronic assessments, the risk is
expressed as a percentage of a maximum acceptable dose (i.e., the dose
which HED has concluded will result in no unreasonable adverse health
effects).  This dose is referred to as the population adjusted dose
(PAD).  The PAD is equivalent to a point of departure (POD, NOAEL,
LOAEL, e.g.) divided by the required uncertainty or safety factors.

For acute and non-cancer chronic exposures, HED is concerned when
estimated dietary risk exceeds 100% of the PAD.  References which
discuss the acute and chronic risk assessments in more detail are
available on the EPA/pesticides web site:  “Available Information on
Assessing Exposure from Pesticides, A User’s Guide,” 6/21/2000, web
link:    HYPERLINK
http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf
http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf  ; or see
SOP 99.6 (8/20/99).

The most recent dietary risk assessment for acetamiprid was conducted by
D. McNeilly (D369019, 12/1/09) which included proposed uses on clover,
small vine climbing fruits, except kiwifruit, subgroup 13-07F (amending
grape use); green house grown tomatoes; and tea.  RD has requested that
HED redo the analyses using 100% percent crop treated for all amended
commodities, i.e., grapes and other subgroup 13-07F commodities, and
tomatoes. 

II.	Residue Information

Tolerances are established for residues of the insecticide acetamiprid
[40 CFR §180.578(a)], N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1-
methylacetamidine, in or on numerous agricultural commodities ranging
from 0.01 ppm on mustard and canola seed to 20 ppm in or on cotton, gin
byproducts.  Tolerances are established for the combined residues of the
insecticide acetamiprid, N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1-
methylacetamidine, and its metabolite
N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano- acetamidine [40 CFR
§180.578(b)] in or on fat and meat of cattle, goat, hog, horse and
sheep, 0.1 ppm; meat by-products of cattle, goat, hog horse and sheep,
0.2 ppm; milk, 0.1 ppm; poultry meat and fat, 0.01 ppm; poultry liver,
0.05 ppm; and egg, 0.01 ppm.

The current acute and chronic dietary exposure assessments include
existing uses and the tolerances proposed by the Interregional Research
Project Number 4 (IR-4).  IR-4 has submitted amended Section 3
registration requests for new uses of acetamiprid on clover grown for
seed, small vine climbing fruits, except kiwifruit, subgroup 13-07F
(amending established grape uses), greenhouse-grown tomatoes, and tea.

Table 1.  Recommended Tolerances

Crop Group or Commodity	Recommended Tol. (ppm)

Clover, forage*	0.10*

* Tolerances with regional restrictions [i.e., 40 CFR §180.578(c)].



Clover, hay*	0.10*

* Tolerances with regional restrictions [i.e., 40 CFR §180.578(c)].



Fruit, small, vine climbing, subgroup 13-07F, except fuzzy kiwifruit   
0.35

Tea	50.0

Tomatoes (greenhouse grown)	Note:  No change is needed to the current
tolerance in fruiting vegetables (Crop Group 8) at 0.2 ppm.



Acute Dietary Exposure Assessment

The acute dietary assessment was conducted using anticipated residues
from field trials [apples; broccoli; cabbage, celery; grapefruit;
grapes; lettuce; oranges; pears; peppers; spinach; tomatoes; stone fruit
(crop group 12); and cucurbits (crop group 9)].  For each of the
above-listed commodities, the individual field trial residue values
(from trials reflecting the 1X application rate and labeled PHI, or
shorter) were incorporated into a residue distribution file (RDF) for
the probabilistic acute dietary exposure assessment.  For field trial
residues below the limit of quantification (LOQ) of 0.01 ppm, a residue
value of ½ LOQ, or 0.005 ppm was assumed.  For cabbage and head
lettuce, residues in the RDF were for the raw agricultural commodity
(RAC) without wrapper leaves.  For commodities with %CT data available,
the RDF includes an indication of the number of zeroes assumed for the
percent of the commodity not treated.  Tolerance level or
HED-recommended tolerance level residues were used for tree nuts,
nectarines, collards, cauliflower, legumes, berries, bulb vegetables and
for livestock commodities.  For tea, the HED-recommended tolerance of 50
ppm was used.

A summary of the RDFs is included in Attachment 1.  The orange RDF was
translated to grapefruit, using the higher percent crop treated estimate
of 5% for oranges (grapefruit was <2.5%).  The plum RDF was translated
to apricots and assumes 100% CT.  These translations are appropriate
since the field trials were conducted on the representative crops, and
cover potential residues in the related crops, and since either no
adjustment for %CT was made (plums and apricots) or a conservative
estimate of %CT was made in these RDFs.  100% crop treated was assumed
for grapes and tomatoes because the use patterns are being amended for
these commodities and projected crop treated estimates are not
available.

Chronic Dietary Exposure Assessment

For the chronic dietary exposure assessment, current and recommended
tolerance-level residues were used, for all RACs and livestock
commodities.  Percent crop treated estimates were used for apple (20%),
broccoli (5%), cabbage (5%), cauliflower (10%), celery (25%), cotton
(5%), grapefruit (2.5%), lemon (5%), lettuce (10%), orange (2.5%), peach
(1%), pear (35%), pepper (2.5%), potato (2.5%), pumpkin (1%), spinach
(5%), and squash (2.5%).  100% crop treated was assumed for grapes and
tomatoes because the use patterns are being amended for these
commodities and projected crop treated estimates are not available.

Processing Factors

The acute dietary exposure assessment was refined with processing
factors for apple juice, orange juice, grapefruit juice, raisins, dried
prunes, tomato paste and tomato puree.  The processing factors were
reviewed in conjunction with residue data used to determine if separate
tolerances were needed for processed commodities.  For all other
commodities, the DEEM™ Version 7.81 default processing factors were
used.  Processing factors from study data were incorporated into the
acute dietary assessment as follows (Table 2):

Table 2.  Summary of Processing Studies Conducted with Acetamiprid.

RAC	Processed Commodity	Processing Factor	Comments

Apple	Juice	0.88	Also used for pear juice

Citrus	Juice	<0.16	0.16X used for both orange and grapefruit juice

Grape	Juice	1	Study data showed RAC tolerance would cover residues in
juice.

	Raisins	0.9	0.9X used in assessment

Tomato	Puree	1.4	1.4X used for puree in assessment

	Paste	3.0	3.0X used for paste in acute assessment.

Plum	Prune, dried	2.9X	2.0X used for dried prunes used in acute
assessment.  The drying factor was translated to dried apricots and
dried peaches in the acute dietary assessment.



For the chronic dietary exposure assessment, the DEEM™ Version 7.81
default processing factors were used for all commodities for which they
are available, with the exception of grape juice, and raisins (dried
prunes and tomato paste have separate tolerances).

Usage Data

In order to refine the dietary exposure estimates for acetamiprid, HED
requested a Screening Level Usage Analysis (SLUA), which was conducted
by the Biological and Economic Analysis Division (BEAD), 6/11/09.  The
SLUA includes estimates of maximum %CT for the acute assessment and
average %CT for determining chronic exposure.  Commodities with the most
significant acetamiprid usage in terms of maximum %CT include pears
(60%), apples (30%), celery (45%), and lettuce (20%).  Commodities with
the most significant usage in terms of lbs ai applied include apples
(10,000), cotton (20,000), and pears (5,000).  The SLUA is included as
Attachment 3.

Table 3.   Percent Crop Treated Data Used in DEEM

Commodity	Avg	Max

Apples	20	30

Broccoli	5	15

Cabbage	5	10

Cauliflower	10	15

Celery	25	45

Cotton	5	5

Grapefruit	2.5	51

Lemons	5	100

Lettuce	10	20

Oranges	2.5	5

Peaches	1	2.5

Pears	35	60

Peppers	2.5	5

Potatoes	2.5	2.5

Pumpkins	1	2.5

Spinach	5	15

Squash	2.5	2.5

1  -  The residue distribution file for oranges which used 5% CT was
also used for grapefruit.  This was higher than the 2.5% CT for
grapefruit estimated by BEAD and is more conservative.

For the acute analysis, maximum %CT was incorporated into RDFs for the
commodities in the above table.  For the chronic analysis, average %CT
was included (as adjustment factor 2) for the commodities listed in the
table above.

Incorporation of Potential Residues in Drinking Water

In a memo dated 6/10/09 [D. Lieu, D364248], EFED notified RD that new
drinking water estimates would not be provided for the proposed use on
red clover (grown for seed only), grape, and tomato (greenhouse) because
the drinking water estimates derived from the uses on citrus and tree
nuts reflect the maximum use patterns for acetamiprid.

In conjunction with the uses on citrus and tree nuts, the Environmental
Fate and Effects Division (EFED) prepared an estimate of potential
residues in drinking water [G. Orrick, Tier I Drinking Water Exposure
Assessment for Acetamiprid on Cucurbit, Stone Fruit and Tree Nut Crop
Groups, 6/21/05, D303582].  EFED stated in a June 10, 2009 memorandum
(D364248, D. Lieu) that this assessment was still valid and should be
used to assess the proposed uses on red clover (grown for seed), grape,
and tomato (greenhouses).  Estimated drinking water concentrations for
acetamiprid in surface water were generated using the FIRST (FQPA Index
Reservoir Screening Tool, v. 1.0) Model.  The results of the model
reflect potential residues in a small drinking water reservoir
surrounded by a runoff-prone watershed, assuming maximum pesticide
application rates and no buffer between the reservoir and treated
fields.  Acetamiprid residues in ground water sources of drinking water
were estimated using the screening regression model SCI-GROW (Screening
Concentration In Ground Water, v. 2.3).  The SCI-GROW residue estimate
is based on environmental fate properties of the pesticide, maximum
application rates, and existing data from small-scale prospective
ground-water monitoring studies in vulnerable sites.

For surface water, the maximum application rate for the existing use of
acetamiprid on citrus was used to provide model estimates of drinking
water concentrations; for ground water, the proposed use on tree nut
crops was used.  However, since modeled surface water residues were
considerably higher than ground water residues, only the surface water
residues were used quantitatively in the dietary (food + water)
assessment.

Table 4.  Tier I Analysis

1-in-10-year EDWCs in surface water and ground water for acetamiprid.

Drinking Water Source	Maximum Use Pattern	Exposure	EDWC

Surface water	Citrus fruit	Peak	20.1     ppb



Annual average	  4.9     ppb

Ground water	Tree nut	Peak & annual average	  1.6     ppt



For the acute assessment, an estimated drinking water concentration of
20.1 ppb was entered into the DEEM™-FCID Model for “water, direct,
all sources” and “water, indirect, all sources.”  For the chronic
assessment, the value of 4.9 ppb was used.  The ground water estimate of
1.6 ppt was much lower than surface water residues; therefore, dietary
exposure and risk calculated using surface water residues are considered
protective of potential exposure through ground water.

III.	Exposure Model and Consumption Information

Acetamiprid acute and chronic dietary exposure assessments were
conducted using the Dietary Exposure Evaluation Model software with the
Food Commodity Intake Database DEEM-FCID™,Version 2.03 which
incorporates consumption data from USDA’s Continuing Surveys of Food
Intakes by Individuals (CSFII), 1994-1996 and 1998.  The 1994-96, 98
data are based on the reported consumption of more than 20,000
individuals over two non-consecutive survey days.  Foods “as
consumed” (e.g., apple pie) are linked to EPA-defined food commodities
(e.g. apples, peeled fruit - cooked; fresh or N/S; baked; or wheat flour
- cooked; fresh or N/S, baked) using publicly available recipe
translation files developed jointly by USDA/ARS and EPA.  For chronic
exposure assessment, consumption data are averaged for the entire U.S.
population and within population subgroups, but for acute exposure
assessment are retained as individual consumption events.  Based on
analysis of the 1994-96, 98 CSFII consumption data, which took into
account dietary patterns and survey respondents, HED concluded that it
is most appropriate to report risk for the following population
subgroups: the general U.S. population, all infants (<1 year old),
children 1-2, children 3-5, children 6-12, youth 13-19, adults 20-49,
females 13-49, and adults 50+ years old.

For chronic dietary exposure assessment, an estimate of the residue
level in each food or food-form (e.g., orange or orange juice) on the
food commodity residue list is multiplied by the average daily
consumption estimate for that food/food form to produce a residue intake
estimate.  The resulting residue intake estimate for each food/food form
is summed with the residue intake estimates for all other food/food
forms on the commodity residue list to arrive at the total average
estimated exposure.  Exposure is expressed in mg/kg body weight/day and
as a percent of the cPAD.  This procedure is performed for each
population subgroup.

For acute exposure assessments, individual one-day food consumption data
are used on an individual-by-individual basis.  The reported consumption
amounts of each food item can be multiplied by a residue point estimate
and summed to obtain a total daily pesticide exposure for a
deterministic exposure assessment, or “matched” in multiple random
pairings with residue values and then summed in a probabilistic
assessment.  The resulting distribution of exposures is expressed as a
percentage of the aPAD on both a user (i.e., only those who reported
eating relevant commodities/food forms) and a per-capita (i.e., those
who reported eating the relevant commodities as well as those who did
not) basis.  In accordance with HED policy, per capita exposure and risk
are reported for all tiers of analysis.  However, for tiers 1 and 2, any
significant differences in user vs. per capita exposure and risk are
specifically identified and noted in the risk assessment.

IV.	Toxicological Information

Doses and endpoints selected for acute and chronic dietary exposure and
risk assessments are summarized as shown in Table 5, below.  Details
regarding hazard characterization and endpoint selection can be found in
the risk assessment associated with the proposed uses [D369474, Dennis
McNeilly, Dec 1, 2009].

Table 5.  Acetamiprid Toxicological Doses/Endpoints for Dietary Risk
Assessment.

Exposure Scenario	Point of Departure	Uncertainty/FQPA Safety Factors
RfD, PAD, Level of Concern 	Study and Toxicological Effects

Acute Dietary

[All Populations]

	NOAEL=10.0

mg/kg/day

	UFA= 10x

UFH= 10x

FQPA SF= 1x

	Acute RfD = 0.10 mg/kg/day

aPAD = 0.10 mg/kg/day	Developmental Neurotox., Rat

LOAEL = 45.0 mg/kg/day based on decreased startle response on PND20/60
in males

Co Critical study - 

Acute Neurotox., Rat

LOAEL = 30 mg/kg/day based on reduced locomotor activity in males.

Chronic Dietary

[all populations]	NOAEL = 7.1 mg/kg/day

	UFA= 10x

UFH= 10x

FQPA SF= 1x

	Chronic RfD =

0.071 mg/kg/day

cPAD = 0.071 mg/kg/day	Chronic/oncogenicity, Rat

LOAEL= 17.5 mg/kg/day based on reduced body weight and body weight gain
(♀) and hepatocellular vacuolation (♂).

Cancer (All routes)	Not likely to be a human carcinogen.



V.	Results/Discussion

As stated above, for acute and chronic assessments, HED is concerned
when dietary risk exceeds 100% of the PAD.  For both the acute and
chronic analyses, the estimated dietary exposures are below HED’s
level of concern for all population subgroups; the most highly exposed
population subgroup for both acute and chronic durations is children 1-2
years old.

Acute dietary exposure estimates at the 99.9th percentile are below
HED’s level of concern for the general US population and all other
population subgroups.  For the US population, the estimated exposure of
0.024 mg/kg/day corresponds to 24% aPAD; for children 1-2 years old, the
estimated exposure of 0.043 mg/kg/day corresponds to an acute dietary
risk of 43% aPAD.

Chronic dietary exposure to acetamiprid is below HED’s level of
concern for the US population and all other population subgroups.  For
the general US population, an estimated exposure of 0.0028 mg/kg/day
corresponds to 4% of the chronic population adjusted dose (cPAD);
children 1-2 years old were the highest exposed population subgroup,
with an estimate of 0.010 mg/kg/day, or 15 % cPAD.  Risks for all
population subgroups are less than 100 % cPAD, and are not of concern.

The results of the acute and chronic analyses are shown in Tables 6 and
7.

Table 6.  Results of Acetamiprid Acute Dietary (Food + Water) Exposure
Analysis.

Population Subgroup	aPAD (mg/kg/day)	95th Percentile	99th Percentile
99.9th Percentile



Exposure (mg/kg/day)	% aPAD	Exposure (mg/kg/day)	% aPAD	Exposure
(mg/kg/day)	% aPAD

General U.S. Population	0.10	0.006752	6.8	0.012367	12	0.023768	24

All Infants (< 1 year old)	0.10	0.012043	12	0.020075	20	0.031227	31

Children 1-2 years old	0.10	0.016770	17	0.025337	25	0.042928	43

Children 3-5 years old	0.10	0.012277	12	0.020279	20	0.034282	34

Children 6-12 years old	0.10	0.007509	7.5	0.013299	13	0.024123	24

Youth 13-19 years old	0.10	0.004686	4.7	0.007810	7.8	0.017682	18

Adults 20-49 years old	0.10	0.004600	4.6	0.007685	7.7	0.015543	16

Adults 50+ years old	0.10	0.004671	4.7	0.007822	7.8	0.013291	13

Females 13-49 years old	0.10	0.004632	4.6	0.007277	7.3	0.013133	13



Table 7.  Summary of Dietary (Food + Water) Exposure and Risk for
Acetamiprid

Population Subgroup	Acute Dietary

(99.9th Percentile)	Chronic Dietary

	Dietary Exposure (mg/kg/day)	% aPAD	Dietary Exposure (mg/kg/day)	% cPAD

General U.S. Population	0.023768	24	0.002835	4.0

All Infants (< 1 year old)	0.031227	31	0.005206	7.3

Children 1-2 years old	0.042928	43	0.010358	15

Children 3-5 years old	0.034282	34	0.007296	10

Children 6-12 years old	0.024123	24	0.004055	5.7

Youth 13-19 years old	0.017682	18	0.002170	3.1

Adults 20-49 years old	0.015543	16	0.002031	2.9

Adults 50+ years old	0.013291	13	0.002130	3.0

Females 13-49 years old	0.013133	13	0.002057	2.9



VI.	Characterization of Inputs/Outputs

The acute dietary exposure assessment for acetamiprid is somewhat
refined, since field trial residue distributions were used in the
probabilistic assessment, and percent crop treated information was
incorporated for some commodities.  In addition, empirical processing
factors for various processed commodities, especially juices, provided
an additional measure of refinement.  However, the assessment is still
somewhat conservative because tolerance-level residues were used for
proposed uses and some of the existing uses, as well as livestock
commodities.  Additional refinements could be made to the assessment
with the use of additional field trial residue data.  Even though the
acute probabilistic assessment has not been completely refined, acute
dietary exposure and risk estimates for acetamiprid are below HED’s
level of concern of 100 % aPAD.

The chronic dietary exposure assessment is unrefined, with the exception
of the use of %CT data cited in Table 3.  For all commodities, tolerance
level residues were used, and DEEM 7.81 default processing factors were
applied.  Further refinements are possible in the future, including the
use of average field trial residues, empirical processing factors and
additional %CT refinements.

VII.	Conclusions

Acute and chronic dietary (food + water) risks for acetamiprid are below
HED’s level of concern for dietary exposure and risk.  Children 1-2
years old are the most highly exposed population subgroup, with risks of
43% aPAD for acute and 15% cPAD for chronic.  Risks were lower for all
other population subgroups, including the general US population.  The
acute and chronic dietary exposure assessments support the new uses
proposed for acetamiprid.

VIII.	List of Attachments

Attachment 1.	Acetamiprid Residue Distribution Files

Attachment 2.	Acetamiprid Screening Level Usage Analysis (SLUA)

Attachment 4.	Acute Residue Input Files

Attachment 5	Summary of Acute Results

Attachment 6.	Chronic Residue Input File

Attachment 7.	Summary of Chronic Results

Attachment 1.	Acetamiprid Residue Distribution Files

Acetamiprid/Apple

TOTALZ=149

Est. Max. %CT = 30

MRID No. 44988626

0.15, 0.16, 0.59, 0.59 0.25

0.29, 0.11, 0.16, 0.12, 0.12

0.24, 0.32, 0.17, 0.18, 0.20

0.23, 0.13, 0.14, 0.21, 0.28

0.09, 0.15, 0.24, 0.28, 0.22

0.39, 0.17, 0.20, 0.45, 0.64

0.22, 0.28, 0.23, 0.23, 0.21

0.25, 0.30, 0.30, 0.25, 0.26

0.26, 0.36, 0.14, 0.16, 0.23

0.27, 0.08, 0.10, 0.30, 0.34

0.25, 0.29, 0.08 0.10, 0.10

0.23, 0.18, 0.21, 0.61, 0.71

0.34, 0.35, 0.21, 0.24	Acetamiprid/Broccoli

Estimated max %CT = 15

TOTALZ=130

MRID No. 44988631

0.02, 0.04, 0.04, 0.05, 0.01

0.01, 0.005, 0.02, 0.01, 0.02

0.005, 0.01, 0.07, 0.11, 0.18

0.25, 0.02, 0.097, 0.10, 0.080

0.092, 0.081, 0.10	Acetamiprid/Cabbage

w/out wrapper leaves, 10 %CT

TOTALZ=180

MRID No. 44988631

0.005, 0.02, 0.005, 0.01, 0.005

0.005, 0.005, 0.005, 0.03, 0.03

0.005, 0.005, 0.01, 0.02, 0.02

0.02, 0.05, 0.05, 0.03, 0.03	Acetamiprid/Celery

Estimated Max. %CT = 45

TOTALZ=20

MRID No. 44988603

0.775, 0.780, 0.167, 0.182

0.396, 0.426, 0.287, 0.352

0.250, 0.290, 0.255, 0.281

0.499, 0.517, 0.068, 0.084

Acetamiprid/Cucurbit

Assume 100%CT

MRID No. 46265701

0.024, 0.038, 0.015, 0.026

0.024, 0.030, 0.038, 0.045

0.082, 0.091, 0.017, 0.019

0.070, 0.090, 0.035, 0.076

0.011, 0.026, 0.011, 0.021

0.035, 0.037, 0.065, 0.142, 0.091, 0.094, 0.075, 0.136

0.053, 0.068, 0.166, 0.221

0.004, 0.075	Acetamiprid/Grape

Assume 100% CT

TOTALZ=0

MRID No. 47716902

0.05, 0.05, 0.03, 0.03, 0.01, 0.01, 0.08, 0.08, 0.17, 0.15, 0.08, 0.09,
0.08, 0.08, 0.2,

0.21, 0.24, 0.25, 0.1, 0.11,

0.06, 0.06, 0.22, 0.22, 0.04, 0.04, 0.07, 0.06, 0.04, 0.03, 0.15, 0.15,
0.24, 0.22, 0.13,

0.13	Acetamiprid/Head Lettuce

MRID No. 44988603

Estimated Max. %CT = 20%

TOTALZ=72

0.155, 0.184, 0.253, 0.294, 0.017, 0.018, 0.047, 0.057

0.005, 0.005, 0.060, 0.061

0.014, 0.014, 0.010, 0.010

0.074, 0.14

	Acetamiprid/Leaf Lettuce

Estimated Maximum %CT=20

TOTALZ=80

MRID No. 44988603

0.716, 1.02, 0.108, 0.123

0.565, 0.646, 0.265, 0.330

0.374, 0.449, 0.848, 1.07

0.098, 0.114, 0.435, 0.479

0.12, 0.18, 0.074, 0.14

Acetamiprid/Orange

TOTALZ=1235

Est. max %CT=5

MRID No. 4498611

0.14, 0.15, 0.11, 0.12, 0.09

0.13, 0.19, 0.29, 0.18, 0.21

0.29, 0.097, 0.11, 0.15, 0.21

0.20, 0.20, 0.058, 0.084, 0.088

0.15, 0.11, 0.15, 0.094, 0.12

0.19, 0.20, 0.19, 0.21, 0.26

0.29, 0.21, 0.23, 0.025, 0.025

0.13, 0.14, 0.081, 0.12, 0.14

0.14, 0.083, 0.12, 0.025, 0.025, 0.025, 0.025, 0.025, 0.098

0.23, 0.27, 0.12, 0.14, 0.079

0.096, 0.087, 0.12, 0.12, 0.16

0.31, 0.37, 0.16, 0.31, 0.26

0.39	Acetamiprid/Peach

Assume 2.5%CT

TOTALZ=1014

MRID No. 46265702

0.294, 0.344, 0.311, 0.565

0.184, 0.225, 0.163, 0.188

0.182, 0.223, 0.117, 0.138

0.153, 0.166, 0.283, 0.387

0.205, 0.233, 0.192, 0.240

0.211, 0.242, 0.0927, 0.133

0.186, 0.199	Acetamiprid/Pear

TOTALZ=42

Est. Max. %CT = 60

MRID No. 44988626

0.15, 0.16, 0.59, 0.59 0.25

0.29, 0.11, 0.16, 0.12, 0.12

0.24, 0.32, 0.17, 0.18, 0.20

0.23, 0.13, 0.14, 0.21, 0.28

0.09, 0.15, 0.24, 0.28, 0.22

0.39, 0.17, 0.20, 0.45, 0.64

0.22, 0.28, 0.23, 0.23, 0.21

0.25, 0.30, 0.30, 0.25, 0.26

0.26, 0.36, 0.14, 0.16, 0.23

0.27, 0.08, 0.10, 0.30, 0.34

0.25, 0.29, 0.08 0.10, 0.10

0.23, 0.18, 0.21, 0.61, 0.71

0.34, 0.35, 0.21, 0.24	Acetamiprid/Peppers

Estimated Max. %CT = 5

TOTALZ=570

MRID No. 44988616

0.005, 0.005, 0.01, 0.02, 0.01

0.01, 0.03, 0.05, 0.03, 0.04

0.01, 0.01, 0.02, 0.03, 0.02

0.02, 0.08, 0.09, 0.03, 0.03

0.06, 0.07, 0.04, 0.07, 0.05

0.06, 0.12, 0.16, 0.08, 0.08

Acetamiprid/Plum

Assume 100%CT

TOTALZ=0

MRID No. 46265702

0.108, 0.116, 0.0648, 0.119

0.0139, 0.0238, 0.0103, 0.0154

0.0515, 0.0624, 0.0401, 0.0429

0.0305, 0.0458, 0.0258, 0.0392	Acetamiprid/Spinach

Assume 15%CT

TOTALZ=125

MRID No. 44988603

0.034, 0.037, 0.184, 0.238

0.026, 0.036, 1.06, 1.20, 2.46

2.58, 0.516, 0.588, 1.95, 2.22

0.463, 0.466, 0.15, 0.23, 0.18

0.18, 0.19, 0.22	Acetamiprid/Tomatoes

Assume %CT=100

TOTALZ=0

MRIDs 44988616/47716903

0.01, 0.01, 0.005, 0.005, 0.005, 0.005, 0.01, 0.04, 0.08, 0.11

0.005, 0.01, 0.07, 0.08, 0.06

0.11, 0.02, 0.03, 0.02, 0.04

0.02, 0.02, 0.03, 0.03, 0.05

0.07, 0.03, 0.05, 0.06, 0.06

0.03, 0.05,  0.02, 0.02, 0.005

0.005, 0.047, 0.052, 0.005

0.005, 0.026, 0.028

	

Summary of Residue Distribution Files (RDF) listed in C:\Documents and
Settings\Dmcneill\My Documents\Acetamiprid\PRIAacetamiprid_acuteAR.r98

 RDF      File        N residues   N residues  N Zeros

  #       Name         w freq's    w/o freq's              

 ----  ------------   ----------   ----------  -------

  1    orange.RDF        0          65          1297 

  2    Apple.RDF         0          64           149 

  3    spinach.rdf       0          22           124 

  4    cabbage.RDF       0          20           180 

  5    peach.RDF         0          26          1114 

  6    Plum.RDF          0          16             0 

  7    Pear.RDF          0          64            43 

  8    Broccoli.RDF      0          23           130 

  9    Celery.RDF        0          16            20 

  10   HeadLettuce.RDF   0          18            72 

  11   LeafLettuce.RDF   0          20            80 

  12   cucurbit.RDF      0          34             0 

  13   Grapes.RDF        0          36             0 

  14   Peppers.RDF       0          30           570 

  15   Tomatoes.RDF      0          42             0 

Attachment 2.	Acetamiprid Screening Level Usage Analysis (SLUA)

.	DEEM-FCID™ Acute Residue Input File

 

U.S. Environmental Protection Agency                                
Ver. 2.02

DEEM-FCID Acute analysis for ACETAMIPRID

Residue file name: C:\Documents and Settings\dmcneill\My
Documents\Actemidprid\PRIAacetamiprid_acuteAR_2010.R98

Analysis Date 01-14-2010             Residue file dated:
01-14-2010/06:49:51/8

Reference dose: aRfD = 0.1 mg/kg bw/day  NOEL = 10 mg/kg bw/day

Comment: Acute/Chronic - UFs = 100

------------------------------------------------------------------------
--------

RDL indices and parameters for Monte Carlo Analysis:

Index Dist Parameter #1           Param #2    Param #3    Comment

  #   Code 

----- ---- ------------           ----------- ----------- ----------

  1    6   orange.RDF

  2    6   Apple.RDF

  3    6   spinach.rdf

  4    6   cabbage.RDF

  5    6   peach.RDF

  6    6   Plum.RDF

  7    6   Pear.RDF

  8    6   Broccoli.RDF

  9    6   Celery.RDF

  10   6   HeadLettuce.RDF

  11   6   LeafLettuce.RDF

  12   6   cucurbit.RDF

  13   6   Grapes.RDF

  14   6   Peppers.RDF

  15   6   Tomatoes.RDF

  EPA    Crop Food Name                         Def Res     Adj.Factors 
RDL  Comment

  Code    Grp                                    (ppm)       #1     #2  
Pntr

-------- ---- -------------------------------  ----------  ------ ------
---  -------

14000030 14   Almond                             0.100000   1.000  1.000
     

14000031 14   Almond-babyfood                    0.100000   1.000  1.000
     

14000040 14   Almond, oil                        0.100000   1.000  1.000
     

14000041 14   Almond, oil-babyfood               0.100000   1.000  1.000
     

04010050 4A   Amaranth, leafy                    3.000000   1.000  1.000
     

11000070 11   Apple, fruit with peel             1.000000   1.000  1.000
  2  

11000080 11   Apple, peeled fruit                1.000000   1.000  1.000
  2  

11000081 11   Apple, peeled fruit-babyfood       1.000000   1.000  1.000
  2  

11000090 11   Apple, dried                       1.000000   8.000  1.000
  2  

11000091 11   Apple, dried-babyfood              1.000000   8.000  1.000
  2  

11000100 11   Apple, juice                       1.000000   0.880  1.000
  2  

11000101 11   Apple, juice-babyfood              1.000000   0.880  1.000
  2  

11000110 11   Apple, sauce                       1.000000   1.000  1.000
  2  

11000111 11   Apple, sauce-babyfood              1.000000   1.000  1.000
  2  

12000120 12   Apricot                            1.200000   1.000  1.000
  6  

12000121 12   Apricot-babyfood                   1.200000   1.000  1.000
  6  

12000130 12   Apricot, dried                     1.200000   2.900  1.000
  6  

12000140 12   Apricot, juice                     1.200000   1.000  1.000
  6  

12000141 12   Apricot, juice-babyfood            1.200000   1.000  1.000
  6  

01030150 1CD  Arrowroot, flour                   0.010000   1.000  1.000
     

01030151 1CD  Arrowroot, flour-babyfood          0.010000   1.000  1.000
     

01030170 1CD  Artichoke, Jerusalem               0.010000   1.000  1.000
     

04010180 4A   Arugula                            3.000000   1.000  1.000
     

09020210 9B   Balsam pear                        0.500000   1.000  1.000
     

06020310 6B   Bean, broad, succulent             0.400000   1.000  1.000
     

06020330 6B   Bean, cowpea, succulent            0.400000   1.000  1.000
     

06020370 6B   Bean, lima, succulent              0.400000   1.000  1.000
     

06010430 6A   Bean, snap, succulent              0.600000   1.000  1.000
     

06010431 6A   Bean, snap, succulent-babyfood     0.600000   1.000  1.000
     

21000440 M    Beef, meat                         0.100000   1.000  1.000
     

21000441 M    Beef, meat-babyfood                0.100000   1.000  1.000
     

21000450 M    Beef, meat, dried                  0.100000   1.920  1.000
     

21000460 M    Beef, meat byproducts              0.200000   1.000  1.000
     

21000461 M    Beef, meat byproducts-babyfood     0.200000   1.000  1.000
     

21000470 M    Beef, fat                          0.100000   1.000  1.000
     

21000471 M    Beef,fat-babyfood                  0.100000   1.000  1.000
     

21000480 M    Beef, kidney                       0.200000   1.000  1.000
     

21000490 M    Beef, liver                        0.200000   1.000  1.000
     

21000491 M    Beef, liver-babyfood               0.200000   1.000  1.000
     

13010550 13A  Blackberry                         1.600000   1.000  1.000
     

13010560 13A  Blackberry, juice                  1.600000   1.000  1.000
     

13010561 13A  Blackberry, juice-babyfood         1.600000   1.000  1.000
     

13020570 13B  Blueberry                          1.600000   1.000  1.000
     

13020571 13B  Blueberry-babyfood                 1.600000   1.000  1.000
     

13010580 13A  Boysenberry                        1.600000   1.000  1.000
     

14000590 14   Brazil nut                         0.100000   1.000  1.000
     

05010610 5A   Broccoli                           1.200000   1.000  1.000
  8  

05010611 5A   Broccoli-babyfood                  1.200000   1.000  1.000
  8  

05010620 5A   Broccoli, Chinese                  1.200000   1.000  1.000
  8  

05020630 5B   Broccoli raab                      1.200000   1.000  1.000
     

05010640 5A   Brussels sprouts                   1.200000   1.000  1.000
     

14000680 14   Butternut                          0.100000   1.000  1.000
     

05010690 5A   Cabbage                            1.200000   1.000  1.000
  4  

05020700 5B   Cabbage, Chinese, bok choy         1.200000   1.000  1.000
     

05010710 5A   Cabbage, Chinese, napa             1.200000   1.000  1.000
     

05010720 5A   Cabbage, Chinese, mustard          1.200000   1.000  1.000
     

09010750 9A   Cantaloupe                         0.500000   1.000  1.000
     

04020760 4B   Cardoon                            3.000000   1.000  1.000
     

09010800 9A   Casaba                             0.500000   1.000  1.000
     

14000810 14   Cashew                             0.100000   1.000  1.000
     

01030820 1CD  Cassava                            0.010000   1.000  1.000
     

01030821 1CD  Cassava-babyfood                   0.010000   1.000  1.000
     

05010830 5A   Cauliflower                        1.200000   1.000  1.000
     

04020850 4B   Celery                             3.000000   1.000  1.000
  9  

04020851 4B   Celery-babyfood                    3.000000   1.000  1.000
  9  

04020860 4B   Celery, juice                      3.000000   1.000  1.000
  9  

04020870 4B   Celtuce                            3.000000   1.000  1.000
     

09020880 9B   Chayote, fruit                     0.500000   1.000  1.000
     

12000900 12   Cherry                             1.200000   1.000  1.000
     

12000901 12   Cherry-babyfood                    1.200000   1.000  1.000
     

12000910 12   Cherry, juice                      1.200000   1.500  1.000
     

12000911 12   Cherry, juice-babyfood             1.200000   1.500  1.000
     

14000920 14   Chestnut                           0.100000   1.000  1.000
     

40000930 P    Chicken, meat                      0.010000   1.000  1.000
     

40000931 P    Chicken, meat-babyfood             0.010000   1.000  1.000
     

40000940 P    Chicken, liver                     0.050000   1.000  1.000
     

40000950 P    Chicken, meat byproducts           0.050000   1.000  1.000
     

40000951 P    Chicken, meat byproducts-babyfoo   0.050000   1.000  1.000
     

40000960 P    Chicken, fat                       0.010000   1.000  1.000
     

40000961 P    Chicken, fat-babyfood              0.010000   1.000  1.000
     

40000970 P    Chicken, skin                      0.010000   1.000  1.000
     

40000971 P    Chicken, skin-babyfood             0.010000   1.000  1.000
     

09021020 9B   Chinese waxgourd                   0.500000   1.000  1.000
     

19011030 19A  Chive                              4.500000   1.000  1.000
     

04011040 4A   Chrysanthemum, garland             3.000000   1.000  1.000
     

10001060 10   Citrus citron                      0.500000   1.000  1.000
     

10001070 10   Citrus hybrids                     0.500000   1.000  1.000
     

10001080 10   Citrus, oil                        0.500000   1.000  1.000
     

05021170 5B   Collards                           1.200000   1.000  1.000
     

95001280 O    Cottonseed, oil                    0.600000   1.000  1.000
     

95001281 O    Cottonseed, oil-babyfood           0.600000   1.000  1.000
     

11001290 11   Crabapple                          1.000000   1.000  1.000
     

95001300 O    Cranberry                          0.600000   1.000  1.000
     

95001301 O    Cranberry-babyfood                 0.600000   1.000  1.000
     

95001310 O    Cranberry, dried                   0.600000   1.000  1.000
     

95001320 O    Cranberry, juice                   0.600000   1.100  1.000
     

95001321 O    Cranberry, juice-babyfood          0.600000   1.100  1.000
     

04011330 4A   Cress, garden                      3.000000   1.000  1.000
     

04011340 4A   Cress, upland                      3.000000   1.000  1.000
     

09021350 9B   Cucumber                           0.500000   1.000  1.000
 12  

13021360 13B  Currant                            1.600000   1.000  1.000
     

13021370 13B  Currant, dried                     1.600000   1.000  1.000
     

04011380 4A   Dandelion, leaves                  3.000000   1.000  1.000
     

01031390 1CD  Dasheen, corm                      0.010000   1.000  1.000
     

13011420 13A  Dewberry                           1.600000   1.000  1.000
     

70001450 P    Egg, whole                         0.010000   1.000  1.000
     

70001451 P    Egg, whole-babyfood                0.010000   1.000  1.000
     

70001460 P    Egg, white                         0.010000   1.000  1.000
     

70001461 P    Egg, white (solids)-babyfood       0.010000   1.000  1.000
     

70001470 P    Egg, yolk                          0.010000   1.000  1.000
     

70001471 P    Egg, yolk-babyfood                 0.010000   1.000  1.000
     

08001480 8    Eggplant                           0.200000   1.000  1.000
     

13021490 13B  Elderberry                         1.600000   1.000  1.000
     

04011500 4A   Endive                             3.000000   1.000  1.000
     

04021520 4B   Fennel, Florence                   3.000000   1.000  1.000
     

14001550 14   Filbert                            0.100000   1.000  1.000
     

14001560 14   Filbert, oil                       0.100000   1.000  1.000
     

03001640 3    Garlic                             0.020000   1.000  1.000
     

03001650 3    Garlic, dried                      0.020000   1.000  1.000
     

03001651 3    Garlic, dried-babyfood             0.020000   1.000  1.000
     

01031660 1CD  Ginger                             0.010000   1.000  1.000
     

01031661 1CD  Ginger-babyfood                    0.010000   1.000  1.000
     

01031670 1CD  Ginger, dried                      0.010000   1.000  1.000
     

23001690 M    Goat, meat                         0.100000   1.000  1.000
     

23001700 M    Goat, meat byproducts              0.200000   1.000  1.000
     

23001710 M    Goat, fat                          0.100000   1.000  1.000
     

23001720 M    Goat, kidney                       0.200000   1.000  1.000
     

23001730 M    Goat, liver                        0.200000   1.000  1.000
     

13021740 13B  Gooseberry                         1.600000   1.000  1.000
     

95001750 O    Grape                              0.350000   1.000  1.000
 13  

95001760 O    Grape, juice                       0.350000   1.000  1.000
 13  

95001761 O    Grape, juice-babyfood              0.350000   1.000  1.000
 13  

95001770 O    Grape, leaves                      0.350000   1.000  1.000
 13  

95001780 O    Grape, raisin                      0.350000   0.900  1.000
 13  

95001790 O    Grape, wine and sherry             0.350000   1.000  1.000
 13  

10001800 10   Grapefruit                         0.500000   1.000  1.000
  1  

10001810 10   Grapefruit, juice                  0.500000   0.160  1.000
  1  

14001850 14   Hickory nut                        0.100000   1.000  1.000
     

09011870 9A   Honeydew melon                     0.500000   1.000  1.000
     

24001890 M    Horse, meat                        0.100000   1.000  1.000
     

13021910 13B  Huckleberry                        1.600000   1.000  1.000
     

05021940 5B   Kale                               1.200000   1.000  1.000
     

95001950 O    Kiwifruit                          0.350000   1.000  1.000
     

05011960 5A   Kohlrabi                           1.200000   1.000  1.000
     

10001970 10   Kumquat                            0.500000   1.000  1.000
     

03001980 3    Leek                               4.500000   1.000  1.000
     

10001990 10   Lemon                              0.500000   1.000  1.000
     

10002000 10   Lemon, juice                       0.500000   2.000  1.000
     

10002001 10   Lemon, juice-babyfood              0.500000   2.000  1.000
     

10002010 10   Lemon, peel                        0.500000   1.000  1.000
     

04012040 4A   Lettuce, head                      3.000000   1.000  1.000
 10  

04012050 4A   Lettuce, leaf                      3.000000   1.000  1.000
 11  

10002060 10   Lime                               0.500000   1.000  1.000
     

10002070 10   Lime, juice                        0.500000   2.000  1.000
     

10002071 10   Lime, juice-babyfood               0.500000   2.000  1.000
     

13012080 13A  Loganberry                         1.600000   1.000  1.000
     

11002100 11   Loquat                             1.000000   1.000  1.000
     

14002130 14   Macadamia nut                      0.100000   1.000  1.000
     

28002210 M    Meat, game                         0.100000   1.000  1.000
     

27002220 D    Milk, fat                          0.100000   1.000  1.000
     

27002221 D    Milk, fat - baby food/infant for   0.100000   1.000  1.000
     

27012230 D    Milk, nonfat solids                0.100000   1.000  1.000
     

27012231 D    Milk, nonfat solids-baby food/in   0.100000   1.000  1.000
     

27022240 D    Milk, water                        0.100000   1.000  1.000
     

27022241 D    Milk, water-babyfood/infant form   0.100000   1.000  1.000
     

27032251 D    Milk, sugar (lactose)-baby food/   0.100000   1.000  1.000
     

05022290 5B   Mustard greens                     1.200000   1.000  1.000
     

12002300 12   Nectarine                          1.200000   1.000  1.000
  5  

08002340 8    Okra                               0.200000   1.000  1.000
     

03002370 3    Onion, dry bulb                    0.020000   1.000  1.000
     

03002371 3    Onion, dry bulb-babyfood           0.020000   1.000  1.000
     

03002380 3    Onion, dry bulb, dried             0.020000   9.000  1.000
     

03002381 3    Onion, dry bulb, dried-babyfood    0.020000   9.000  1.000
     

03002390 3    Onion, green                       4.500000   1.000  1.000
     

10002400 10   Orange                             0.500000   1.000  1.000
  1  

10002410 10   Orange, juice                      0.500000   0.160  1.000
  1  

10002411 10   Orange, juice-babyfood             0.500000   0.160  1.000
  1  

10002420 10   Orange, peel                       0.500000   1.000  1.000
  1  

04012480 4A   Parsley, leaves                    3.000000   1.000  1.000
     

06022550 6B   Pea, succulent                     0.400000   1.000  1.000
     

06022551 6B   Pea, succulent-babyfood            0.400000   1.000  1.000
     

06012570 6A   Pea, edible podded, succulent      0.600000   1.000  1.000
     

06022590 6B   Pea, pigeon, succulent             0.400000   1.000  1.000
     

12002600 12   Peach                              1.200000   1.000  1.000
  5  

12002601 12   Peach-babyfood                     1.200000   1.000  1.000
  5  

12002610 12   Peach, dried                       1.200000   2.900  1.000
  5  

12002611 12   Peach, dried-babyfood              1.200000   2.900  1.000
  5  

12002620 12   Peach, juice                       1.200000   1.000  1.000
  5  

12002621 12   Peach, juice-babyfood              1.200000   1.000  1.000
  5  

11002660 11   Pear                               1.000000   1.000  1.000
  7  

11002661 11   Pear-babyfood                      1.000000   1.000  1.000
  7  

11002670 11   Pear, dried                        1.000000   6.250  1.000
  7  

11002680 11   Pear, juice                        1.000000   0.880  1.000
  7  

11002681 11   Pear, juice-babyfood               1.000000   0.880  1.000
  7  

14002690 14   Pecan                              0.100000   1.000  1.000
     

08002700 8    Pepper, bell                       0.200000   1.000  1.000
 14  

08002701 8    Pepper, bell-babyfood              0.200000   1.000  1.000
 14  

08002710 8    Pepper, bell, dried                0.200000   1.000  1.000
 14  

08002711 8    Pepper, bell, dried-babyfood       0.200000   1.000  1.000
 14  

08002720 8    Pepper, nonbell                    0.200000   1.000  1.000
 14  

08002721 8    Pepper, nonbell-babyfood           0.200000   1.000  1.000
 14  

08002730 8    Pepper, nonbell, dried             0.200000   1.000  1.000
 14  

14002820 14   Pistachio                          0.100000   1.000  1.000
     

12002850 12   Plum                               1.200000   1.000  1.000
  6  

12002851 12   Plum-babyfood                      1.200000   1.000  1.000
  6  

12002860 12   Plum, prune, fresh                 0.200000   1.000  1.000
  6  

12002861 12   Plum, prune, fresh-babyfood        0.200000   1.000  1.000
  6  

12002870 12   Plum, prune, dried                 0.400000   2.900  1.000
  6  

12002871 12   Plum, prune, dried-babyfood        0.400000   2.900  1.000
  6  

12002880 12   Plum, prune, juice                 0.200000   1.400  1.000
  6  

12002881 12   Plum, prune, juice-babyfood        0.200000   1.400  1.000
  6  

25002900 M    Pork, meat                         0.100000   1.000  1.000
     

25002901 M    Pork, meat-babyfood                0.100000   1.000  1.000
     

25002910 M    Pork, skin                         0.100000   1.000  1.000
     

25002920 M    Pork, meat byproducts              0.200000   1.000  1.000
     

25002921 M    Pork, meat byproducts-babyfood     0.200000   1.000  1.000
     

25002930 M    Pork, fat                          0.100000   1.000  1.000
     

25002931 M    Pork, fat-babyfood                 0.100000   1.000  1.000
     

25002940 M    Pork, kidney                       0.200000   1.000  1.000
     

25002950 M    Pork, liver                        0.200000   1.000  1.000
     

01032960 1C   Potato, chips                      0.010000   1.000  1.000
     

01032970 1C   Potato, dry (granules/ flakes)     0.010000   6.500  1.000
     

01032971 1C   Potato, dry (granules/ flakes)-b   0.010000   6.500  1.000
     

01032980 1C   Potato, flour                      0.010000   6.500  1.000
     

01032981 1C   Potato, flour-babyfood             0.010000   6.500  1.000
     

01032990 1C   Potato, tuber, w/peel              0.010000   1.000  1.000
     

01032991 1C   Potato, tuber, w/peel-babyfood     0.010000   1.000  1.000
     

01033000 1C   Potato, tuber, w/o peel            0.010000   1.000  1.000
     

01033001 1C   Potato, tuber, w/o peel-babyfood   0.010000   1.000  1.000
     

60003010 P    Poultry, other, meat               0.010000   1.000  1.000
     

60003020 P    Poultry, other, liver              0.050000   1.000  1.000
     

60003030 P    Poultry, other, meat byproducts    0.050000   1.000  1.000
     

60003040 P    Poultry, other, fat                0.010000   1.000  1.000
     

60003050 P    Poultry, other, skin               0.010000   1.000  1.000
     

10003070 10   Pummelo                            0.500000   1.000  1.000
     

09023080 9B   Pumpkin                            0.500000   1.000  1.000
     

09023090 9B   Pumpkin, seed                      0.500000   1.000  1.000
     

11003100 11   Quince                             1.000000   1.000  1.000
     

29003120 M    Rabbit, meat                       0.100000   1.000  1.000
     

04013130 4A   Radicchio                          3.000000   1.000  1.000
     

05023180 5B   Rape greens                        1.200000   1.000  1.000
     

20003190 20   Rapeseed, oil                      0.010000   1.000  1.000
     

20003191 20   Rapeseed, oil-babyfood             0.010000   1.000  1.000
     

13013200 13A  Raspberry                          1.600000   1.000  1.000
     

13013201 13A  Raspberry-babyfood                 1.600000   1.000  1.000
     

13013210 13A  Raspberry, juice                   1.600000   1.000  1.000
     

13013211 13A  Raspberry, juice-babyfood          1.600000   1.000  1.000
     

04023220 4B   Rhubarb                            3.000000   1.000  1.000
     

03003380 3    Shallot                            0.020000   1.000  1.000
     

26003390 M    Sheep, meat                        0.100000   1.000  1.000
     

26003391 M    Sheep, meat-babyfood               0.100000   1.000  1.000
     

26003400 M    Sheep, meat byproducts             0.200000   1.000  1.000
     

26003410 M    Sheep, fat                         0.100000   1.000  1.000
     

26003411 M    Sheep, fat-babyfood                0.100000   1.000  1.000
     

26003420 M    Sheep, kidney                      0.200000   1.000  1.000
     

26003430 M    Sheep, liver                       0.200000   1.000  1.000
     

19023540 19B  Spices, other                      0.010000   1.000  1.000
     

19023541 19B  Spices, other-babyfood             0.010000   1.000  1.000
     

04013550 4A   Spinach                            3.000000   1.000  1.000
  3  

04013551 4A   Spinach-babyfood                   3.000000   1.000  1.000
  3  

09023560 9B   Squash, summer                     0.500000   1.000  1.000
 12  

09023561 9B   Squash, summer-babyfood            0.500000   1.000  1.000
 12  

09023570 9B   Squash, winter                     0.500000   1.000  1.000
 12  

09023571 9B   Squash, winter-babyfood            0.500000   1.000  1.000
 12  

95003590 O    Strawberry                         0.600000   1.000  1.000
     

95003591 O    Strawberry-babyfood                0.600000   1.000  1.000
     

95003600 O    Strawberry, juice                  0.600000   1.000  1.000
     

95003601 O    Strawberry, juice-babyfood         0.600000   1.000  1.000
     

01033660 1CD  Sweet potato                       0.010000   1.000  1.000
     

01033661 1CD  Sweet potato-babyfood              0.010000   1.000  1.000
     

04023670 4B   Swiss chard                        3.000000   1.000  1.000
     

10003690 10   Tangerine                          0.500000   1.000  1.000
     

10003700 10   Tangerine, juice                   0.500000   2.300  1.000
     

01033710 1CD  Tanier, corm                       0.010000   1.000  1.000
     

95003720 O    Tea, dried                        50.000000   1.000  1.000
     

95003730 O    Tea, instant                      50.000000   1.000  1.000
     

08003740 8    Tomatillo                          0.200000   1.000  1.000
 15  

08003750 8    Tomato                             0.200000   1.000  1.000
 15  

08003751 8    Tomato-babyfood                    0.200000   1.000  1.000
 15  

08003760 8    Tomato, paste                      0.400000   3.000  1.000
 15  

08003761 8    Tomato, paste-babyfood             0.400000   3.000  1.000
 15  

08003770 8    Tomato, puree                      0.200000   1.400  1.000
 15  

08003771 8    Tomato, puree-babyfood             0.200000   1.400  1.000
 15  

08003780 8    Tomato, dried                      0.200000  14.300  1.000
 15  

08003781 8    Tomato, dried-babyfood             0.200000  14.300  1.000
 15  

08003790 8    Tomato, juice                      0.200000   1.500  1.000
 15  

50003820 P    Turkey, meat                       0.010000   1.000  1.000
     

50003821 P    Turkey, meat-babyfood              0.010000   1.000  1.000
     

50003830 P    Turkey, liver                      0.050000   1.000  1.000
     

50003831 P    Turkey, liver-babyfood             0.050000   1.000  1.000
     

50003840 P    Turkey, meat byproducts            0.050000   1.000  1.000
     

50003841 P    Turkey, meat byproducts-babyfood   0.050000   1.000  1.000
     

50003850 P    Turkey, fat                        0.010000   1.000  1.000
     

50003851 P    Turkey, fat-babyfood               0.010000   1.000  1.000
     

50003860 P    Turkey, skin                       0.010000   1.000  1.000
     

50003861 P    Turkey, skin-babyfood              0.010000   1.000  1.000
     

01033870 1CD  Turmeric                           0.010000   1.000  1.000
     

05023890 5B   Turnip, greens                     1.200000   1.000  1.000
     

14003910 14   Walnut                             0.100000   1.000  1.000
     

86010000 O    Water, direct, all sources         0.020100   1.000  1.000
     

86020000 O    Water, indirect, all sources       0.020100   1.000  1.000
     

09013990 9A   Watermelon                         0.500000   1.000  1.000
     

09014000 9A   Watermelon, juice                  0.500000   1.000  1.000
     

01034060 1CD  Yam, true                          0.010000   1.000  1.000
     

01034070 1CD  Yam bean                           0.010000   1.000  1.000
     

 

Attachment 4.	Summary of DEEM-FCID™ Acute Results

U.S. Environmental Protection Agency                                 
Ver. 2.02

DEEM-FCID ACUTE Analysis for ACETAMIPRID                        
(1994-98 data)

Residue file: PRIAacetamiprid_acuteAR_2010.R98    Adjustment factor #2
NOT used.

Analysis Date: 01-14-2010/06:56:20    Residue file dated:
01-14-2010/06:49:51/8

NOEL (Acute) =  10.000000 mg/kg body-wt/day

Daily totals for food and foodform consumption used.

MC iterations = 1000      MC list in residue file     MC seed = 10

Run Comment: "Acute/Chronic - UFs = 100"

========================================================================
=======

Summary calculations (per capita):

      95th Percentile             99th Percentile             99.9th
Percentile

 Exposure  % aRfD     MOE    Exposure  % aRfD     MOE    Exposure  %
aRfD     MOE  

---------- ------- -------- ---------- ------- -------- ----------
------- --------

U.S. Population:

  0.006752    6.75    1480    0.012367   12.37     808    0.023768  
23.77     420  

All infants:

  0.012043   12.04     830    0.020075   20.08     498    0.031227  
31.23     320  

Children 1-2 yrs:

  0.016770   16.77     596    0.025337   25.34     394    0.042928  
42.93     232  

Children 3-5 yrs:

  0.012277   12.28     814    0.020279   20.28     493    0.034282  
34.28     291  

Children 6-12 yrs:

  0.007509    7.51    1331    0.013299   13.30     751    0.024123  
24.12     414  

Youth 13-19 yrs:

  0.004686    4.69    2133    0.007810    7.81    1280    0.017682  
17.68     565  

Adults 20-49 yrs:

  0.004600    4.60    2173    0.007685    7.69    1301    0.015543  
15.54     643  

Adults 50+ yrs:

  0.004671    4.67    2140    0.007822    7.82    1278    0.013291  
13.29     752  

Females 13-49 yrs:

  0.004632    4.63    2158    0.007277    7.28    1374    0.013133  
13.13     761  

Attachment 5.	DEEM-FCID™ Chronic Residue Input File

U.S. Environmental Protection Agency                                
Ver. 2.00

DEEM-FCID Chronic analysis for ACETAMIPRID                       
1994-98 data

Residue file: C:\Documents and Settings\dmcneill\My
Documents\Actemidprid\PRIADNTacetamipridCT_chronic.R98

                                                               Adjust.
#2 used

Analysis Date 01-12-2010             Residue file dated:
01-12-2010/08:15:02/8

Reference dose (RfD) = 0.071 mg/kg bw/day

Comment:Acute/Chronic - UFs = 100

------------------------------------------------------------------------
--------

Food Crop                                       Residue      
Adj.Factors      Comment

EPA Code  Grp  Food Name                          (ppm)       

                                                             #1        
#2 

-------- ---- -------------------------------   ---------- ------    
------   -------

14000030 14   Almond                             0.100000   1.000     
1.000   

14000031 14   Almond-babyfood                    0.100000   1.000     
1.000   

14000040 14   Almond, oil                        0.100000   1.000     
1.000   

14000041 14   Almond, oil-babyfood               0.100000   1.000     
1.000   

04010050 4A   Amaranth, leafy                    3.000000   1.000     
1.000   

11000070 11   Apple, fruit with peel             1.000000   1.000     
0.200   

11000080 11   Apple, peeled fruit                1.000000   1.000     
0.200   

11000081 11   Apple, peeled fruit-babyfood       1.000000   1.000     
0.200   

11000090 11   Apple, dried                       1.000000   8.000     
0.200   

11000091 11   Apple, dried-babyfood              1.000000   8.000     
0.200   

11000100 11   Apple, juice                       1.000000   1.300     
0.200   

11000101 11   Apple, juice-babyfood              1.000000   1.300     
0.200   

11000110 11   Apple, sauce                       1.000000   1.000     
0.200   

11000111 11   Apple, sauce-babyfood              1.000000   1.000     
0.200   

12000120 12   Apricot                            1.200000   1.000     
1.000   

12000121 12   Apricot-babyfood                   1.200000   1.000     
1.000   

12000130 12   Apricot, dried                     1.200000   6.000     
1.000   

12000140 12   Apricot, juice                     1.200000   1.000     
1.000   

12000141 12   Apricot, juice-babyfood            1.200000   1.000     
1.000   

01030150 1CD  Arrowroot, flour                   0.010000   1.000     
1.000   

01030151 1CD  Arrowroot, flour-babyfood          0.010000   1.000     
1.000   

01030170 1CD  Artichoke, Jerusalem               0.010000   1.000     
1.000   

04010180 4A   Arugula                            3.000000   1.000     
1.000   

09020210 9B   Balsam pear                        0.500000   1.000     
1.000   

06020310 6B   Bean, broad, succulent             0.400000   1.000     
1.000   

06020330 6B   Bean, cowpea, succulent            0.400000   1.000     
1.000   

06020370 6B   Bean, lima, succulent              0.400000   1.000     
1.000   

06010430 6A   Bean, snap, succulent              0.600000   1.000     
1.000   

06010431 6A   Bean, snap, succulent-babyfood     0.600000   1.000     
1.000   

21000440 M    Beef, meat                         0.100000   1.000     
1.000   

21000441 M    Beef, meat-babyfood                0.100000   1.000     
1.000   

21000450 M    Beef, meat, dried                  0.100000   1.920     
1.000   

21000460 M    Beef, meat byproducts              0.200000   1.000     
1.000   

21000461 M    Beef, meat byproducts-babyfood     0.200000   1.000     
1.000   

21000470 M    Beef, fat                          0.100000   1.000     
1.000   

21000471 M    Beef,fat-babyfood                  0.100000   1.000     
1.000   

21000480 M    Beef, kidney                       0.200000   1.000     
1.000   

21000490 M    Beef, liver                        0.200000   1.000     
1.000   

21000491 M    Beef, liver-babyfood               0.200000   1.000     
1.000   

13010550 13A  Blackberry                         1.600000   1.000     
1.000   

13010560 13A  Blackberry, juice                  1.600000   1.000     
1.000   

13010561 13A  Blackberry, juice-babyfood         1.600000   1.000     
1.000   

13020570 13B  Blueberry                          1.600000   1.000     
1.000   

13020571 13B  Blueberry-babyfood                 1.600000   1.000     
1.000   

13010580 13A  Boysenberry                        1.600000   1.000     
1.000   

14000590 14   Brazil nut                         0.100000   1.000     
1.000   

05010610 5A   Broccoli                           1.200000   1.000     
0.050   

05010611 5A   Broccoli-babyfood                  1.200000   1.000     
0.050   

05010620 5A   Broccoli, Chinese                  1.200000   1.000     
1.000   

05020630 5B   Broccoli raab                      1.200000   1.000     
1.000   

05010640 5A   Brussels sprouts                   1.200000   1.000     
1.000   

14000680 14   Butternut                          0.100000   1.000     
1.000   

05010690 5A   Cabbage                            1.200000   1.000     
0.050   

05020700 5B   Cabbage, Chinese, bok choy         1.200000   1.000     
1.000   

05010710 5A   Cabbage, Chinese, napa             1.200000   1.000     
1.000   

05010720 5A   Cabbage, Chinese, mustard          1.200000   1.000     
1.000   

09010750 9A   Cantaloupe                         0.500000   1.000     
1.000   

04020760 4B   Cardoon                            3.000000   1.000     
1.000   

09010800 9A   Casaba                             0.500000   1.000     
1.000   

14000810 14   Cashew                             0.100000   1.000     
1.000   

01030820 1CD  Cassava                            0.010000   1.000     
1.000   

01030821 1CD  Cassava-babyfood                   0.010000   1.000     
1.000   

05010830 5A   Cauliflower                        1.200000   1.000     
0.100   

04020850 4B   Celery                             3.000000   1.000     
0.250   

04020851 4B   Celery-babyfood                    3.000000   1.000     
0.250   

04020860 4B   Celery, juice                      3.000000   1.000     
0.250   

04020870 4B   Celtuce                            3.000000   1.000     
1.000   

09020880 9B   Chayote, fruit                     0.500000   1.000     
1.000   

12000900 12   Cherry                             1.200000   1.000     
1.000   

12000901 12   Cherry-babyfood                    1.200000   1.000     
1.000   

12000910 12   Cherry, juice                      1.200000   1.500     
1.000   

12000911 12   Cherry, juice-babyfood             1.200000   1.500     
1.000   

14000920 14   Chestnut                           0.100000   1.000     
1.000   

40000930 P    Chicken, meat                      0.010000   1.000     
1.000   

40000931 P    Chicken, meat-babyfood             0.010000   1.000     
1.000   

40000940 P    Chicken, liver                     0.050000   1.000     
1.000   

40000950 P    Chicken, meat byproducts           0.050000   1.000     
1.000   

40000951 P    Chicken, meat byproducts-babyfoo   0.050000   1.000     
1.000   

40000960 P    Chicken, fat                       0.010000   1.000     
1.000   

40000961 P    Chicken, fat-babyfood              0.010000   1.000     
1.000   

40000970 P    Chicken, skin                      0.010000   1.000     
1.000   

40000971 P    Chicken, skin-babyfood             0.010000   1.000     
1.000   

09021020 9B   Chinese waxgourd                   0.500000   1.000     
1.000   

19011030 19A  Chive                              4.500000   1.000     
1.000   

04011040 4A   Chrysanthemum, garland             3.000000   1.000     
1.000   

10001060 10   Citrus citron                      0.500000   1.000     
1.000   

10001070 10   Citrus hybrids                     0.500000   1.000     
1.000   

10001080 10   Citrus, oil                        0.500000   1.000     
1.000   

05021170 5B   Collards                           1.200000   1.000     
1.000   

95001280 O    Cottonseed, oil                    0.600000   1.000     
0.050   

95001281 O    Cottonseed, oil-babyfood           0.600000   1.000     
0.050   

11001290 11   Crabapple                          1.000000   1.000     
1.000   

95001300 O    Cranberry                          0.600000   1.000     
1.000   

95001301 O    Cranberry-babyfood                 0.600000   1.000     
1.000   

95001310 O    Cranberry, dried                   0.600000   1.000     
1.000   

95001320 O    Cranberry, juice                   0.600000   1.100     
1.000   

95001321 O    Cranberry, juice-babyfood          0.600000   1.100     
1.000   

04011330 4A   Cress, garden                      3.000000   1.000     
1.000   

04011340 4A   Cress, upland                      3.000000   1.000     
1.000   

09021350 9B   Cucumber                           0.500000   1.000     
1.000   

13021360 13B  Currant                            1.600000   1.000     
1.000   

13021370 13B  Currant, dried                     1.600000   1.000     
1.000   

04011380 4A   Dandelion, leaves                  3.000000   1.000     
1.000   

01031390 1CD  Dasheen, corm                      0.010000   1.000     
1.000   

13011420 13A  Dewberry                           1.600000   1.000     
1.000   

70001450 P    Egg, whole                         0.010000   1.000     
1.000   

70001451 P    Egg, whole-babyfood                0.010000   1.000     
1.000   

70001460 P    Egg, white                         0.010000   1.000     
1.000   

70001461 P    Egg, white (solids)-babyfood       0.010000   1.000     
1.000   

70001470 P    Egg, yolk                          0.010000   1.000     
1.000   

70001471 P    Egg, yolk-babyfood                 0.010000   1.000     
1.000   

08001480 8    Eggplant                           0.200000   1.000     
1.000   

13021490 13B  Elderberry                         1.600000   1.000     
1.000   

04011500 4A   Endive                             3.000000   1.000     
1.000   

04021520 4B   Fennel, Florence                   3.000000   1.000     
1.000   

14001550 14   Filbert                            0.100000   1.000     
1.000   

14001560 14   Filbert, oil                       0.100000   1.000     
1.000   

03001640 3    Garlic                             0.020000   1.000     
1.000   

03001650 3    Garlic, dried                      0.020000   1.000     
1.000   

03001651 3    Garlic, dried-babyfood             0.020000   1.000     
1.000   

01031660 1CD  Ginger                             0.010000   1.000     
1.000   

01031661 1CD  Ginger-babyfood                    0.010000   1.000     
1.000   

01031670 1CD  Ginger, dried                      0.010000   1.000     
1.000   

23001690 M    Goat, meat                         0.100000   1.000     
1.000   

23001700 M    Goat, meat byproducts              0.200000   1.000     
1.000   

23001710 M    Goat, fat                          0.100000   1.000     
1.000   

23001720 M    Goat, kidney                       0.200000   1.000     
1.000   

23001730 M    Goat, liver                        0.200000   1.000     
1.000   

13021740 13B  Gooseberry                         1.600000   1.000     
1.000   

95001750 O    Grape                              0.350000   1.000     
1.000   

95001760 O    Grape, juice                       0.350000   1.000     
1.000   

95001761 O    Grape, juice-babyfood              0.350000   1.000     
1.000   

95001770 O    Grape, leaves                      0.350000   1.000     
1.000   

95001780 O    Grape, raisin                      0.350000   0.900     
1.000   

95001790 O    Grape, wine and sherry             0.350000   1.000     
1.000   

10001800 10   Grapefruit                         0.500000   1.000     
0.025   

10001810 10   Grapefruit, juice                  0.500000   2.100     
0.025   

14001850 14   Hickory nut                        0.100000   1.000     
1.000   

09011870 9A   Honeydew melon                     0.500000   1.000     
1.000   

24001890 M    Horse, meat                        0.100000   1.000     
1.000   

13021910 13B  Huckleberry                        1.600000   1.000     
1.000   

05021940 5B   Kale                               1.200000   1.000     
1.000   

95001950 O    Kiwifruit                          0.350000   1.000     
1.000   

05011960 5A   Kohlrabi                           1.200000   1.000     
1.000   

10001970 10   Kumquat                            0.500000   1.000     
1.000   

10001990 10   Lemon                              0.500000   1.000     
0.050   

10002000 10   Lemon, juice                       0.500000   2.000     
0.050   

10002001 10   Lemon, juice-babyfood              0.500000   2.000     
0.050   

10002010 10   Lemon, peel                        0.500000   1.000     
0.050   

04012040 4A   Lettuce, head                      3.000000   1.000     
0.100   

04012050 4A   Lettuce, leaf                      3.000000   1.000     
0.100   

10002060 10   Lime                               0.500000   1.000     
1.000   

10002070 10   Lime, juice                        0.500000   2.000     
1.000   

10002071 10   Lime, juice-babyfood               0.500000   2.000     
1.000   

13012080 13A  Loganberry                         1.600000   1.000     
1.000   

11002100 11   Loquat                             1.000000   1.000     
1.000   

14002130 14   Macadamia nut                      0.100000   1.000     
1.000   

28002210 M    Meat, game                         0.100000   1.000     
1.000   

27002220 D    Milk, fat                          0.100000   1.000     
1.000   

27002221 D    Milk, fat - baby food/infant for   0.100000   1.000     
1.000   

27012230 D    Milk, nonfat solids                0.100000   1.000     
1.000   

27012231 D    Milk, nonfat solids-baby food/in   0.100000   1.000     
1.000   

27022240 D    Milk, water                        0.100000   1.000     
1.000   

27022241 D    Milk, water-babyfood/infant form   0.100000   1.000     
1.000   

27032251 D    Milk, sugar (lactose)-baby food/   0.100000   1.000     
1.000   

05022290 5B   Mustard greens                     1.200000   1.000     
1.000   

12002300 12   Nectarine                          1.200000   1.000     
1.000   

08002340 8    Okra                               0.200000   1.000     
1.000   

03002370 3    Onion, dry bulb                    0.020000   1.000     
1.000   

03002371 3    Onion, dry bulb-babyfood           0.020000   1.000     
1.000   

03002380 3    Onion, dry bulb, dried             0.020000   9.000     
1.000   

03002381 3    Onion, dry bulb, dried-babyfood    0.020000   9.000     
1.000   

03002390 3    Onion, green                       4.500000   1.000     
1.000   

10002400 10   Orange                             0.500000   1.000     
0.025   

10002410 10   Orange, juice                      0.500000   1.800     
0.025   

10002411 10   Orange, juice-babyfood             0.500000   1.800     
0.025   

10002420 10   Orange, peel                       0.500000   1.000     
0.025   

04012480 4A   Parsley, leaves                    3.000000   1.000     
1.000   

06022550 6B   Pea, succulent                     0.400000   1.000     
1.000   

06022551 6B   Pea, succulent-babyfood            0.400000   1.000     
1.000   

06012570 6A   Pea, edible podded, succulent      0.600000   1.000     
1.000   

06022590 6B   Pea, pigeon, succulent             0.400000   1.000     
1.000   

12002600 12   Peach                              1.200000   1.000     
0.010   

12002601 12   Peach-babyfood                     1.200000   1.000     
0.010   

12002610 12   Peach, dried                       1.200000   7.000     
0.010   

12002611 12   Peach, dried-babyfood              1.200000   7.000     
0.010   

12002620 12   Peach, juice                       1.200000   1.000     
0.010   

12002621 12   Peach, juice-babyfood              1.200000   1.000     
0.010   

11002660 11   Pear                               1.000000   1.000     
0.350   

11002661 11   Pear-babyfood                      1.000000   1.000     
0.350   

11002670 11   Pear, dried                        1.000000   6.250     
0.350   

11002680 11   Pear, juice                        1.000000   1.000     
0.350   

11002681 11   Pear, juice-babyfood               1.000000   1.000     
0.350   

14002690 14   Pecan                              0.100000   1.000     
1.000   

08002700 8    Pepper, bell                       0.200000   1.000     
0.025   

08002701 8    Pepper, bell-babyfood              0.200000   1.000     
0.025   

08002710 8    Pepper, bell, dried                0.200000   1.000     
0.025   

08002711 8    Pepper, bell, dried-babyfood       0.200000   1.000     
0.025   

08002720 8    Pepper, nonbell                    0.200000   1.000     
0.025   

08002721 8    Pepper, nonbell-babyfood           0.200000   1.000     
0.025   

08002730 8    Pepper, nonbell, dried             0.200000   1.000     
0.025   

14002820 14   Pistachio                          0.100000   1.000     
1.000   

12002850 12   Plum                               1.200000   1.000     
1.000   

12002851 12   Plum-babyfood                      1.200000   1.000     
1.000   

12002860 12   Plum, prune, fresh                 0.200000   1.000     
1.000   

12002861 12   Plum, prune, fresh-babyfood        0.200000   1.000     
1.000   

12002870 12   Plum, prune, dried                 0.400000   1.000     
1.000   

12002871 12   Plum, prune, dried-babyfood        0.400000   1.000     
1.000   

12002880 12   Plum, prune, juice                 0.200000   1.400     
1.000   

12002881 12   Plum, prune, juice-babyfood        0.200000   1.400     
1.000   

25002900 M    Pork, meat                         0.100000   1.000     
1.000   

25002901 M    Pork, meat-babyfood                0.100000   1.000     
1.000   

25002910 M    Pork, skin                         0.100000   1.000     
1.000   

25002920 M    Pork, meat byproducts              0.200000   1.000     
1.000   

25002921 M    Pork, meat byproducts-babyfood     0.200000   1.000     
1.000   

25002930 M    Pork, fat                          0.100000   1.000     
1.000   

25002931 M    Pork, fat-babyfood                 0.100000   1.000     
1.000   

25002940 M    Pork, kidney                       0.200000   1.000     
1.000   

25002950 M    Pork, liver                        0.200000   1.000     
1.000   

01032960 1C   Potato, chips                      0.010000   1.000     
0.025   

01032970 1C   Potato, dry (granules/ flakes)     0.010000   6.500     
0.025   

01032971 1C   Potato, dry (granules/ flakes)-b   0.010000   6.500     
0.025   

01032980 1C   Potato, flour                      0.010000   6.500     
0.025   

01032981 1C   Potato, flour-babyfood             0.010000   6.500     
0.025   

01032990 1C   Potato, tuber, w/peel              0.010000   1.000     
0.025   

01032991 1C   Potato, tuber, w/peel-babyfood     0.010000   1.000     
0.025   

01033000 1C   Potato, tuber, w/o peel            0.010000   1.000     
0.025   

01033001 1C   Potato, tuber, w/o peel-babyfood   0.010000   1.000     
0.025   

60003010 P    Poultry, other, meat               0.010000   1.000     
1.000   

60003020 P    Poultry, other, liver              0.050000   1.000     
1.000   

60003030 P    Poultry, other, meat byproducts    0.050000   1.000     
1.000   

60003040 P    Poultry, other, fat                0.010000   1.000     
1.000   

60003050 P    Poultry, other, skin               0.010000   1.000     
1.000   

10003070 10   Pummelo                            0.500000   1.000     
1.000   

09023080 9B   Pumpkin                            0.500000   1.000     
0.010   

09023090 9B   Pumpkin, seed                      0.500000   1.000     
0.010   

11003100 11   Quince                             1.000000   1.000     
1.000   

29003120 M    Rabbit, meat                       0.100000   1.000     
1.000   

04013130 4A   Radicchio                          3.000000   1.000     
1.000   

05023180 5B   Rape greens                        1.200000   1.000     
1.000   

20003190 20   Rapeseed, oil                      0.010000   1.000     
1.000   

20003191 20   Rapeseed, oil-babyfood             0.010000   1.000     
1.000   

13013200 13A  Raspberry                          1.600000   1.000     
1.000   

13013201 13A  Raspberry-babyfood                 1.600000   1.000     
1.000   

13013210 13A  Raspberry, juice                   1.600000   1.000     
1.000   

13013211 13A  Raspberry, juice-babyfood          1.600000   1.000     
1.000   

04023220 4B   Rhubarb                            3.000000   1.000     
1.000   

03003380 3    Shallot                            0.020000   1.000     
1.000   

26003390 M    Sheep, meat                        0.100000   1.000     
1.000   

26003391 M    Sheep, meat-babyfood               0.100000   1.000     
1.000   

26003400 M    Sheep, meat byproducts             0.200000   1.000     
1.000   

26003410 M    Sheep, fat                         0.100000   1.000     
1.000   

26003411 M    Sheep, fat-babyfood                0.100000   1.000     
1.000   

26003420 M    Sheep, kidney                      0.200000   1.000     
1.000   

26003430 M    Sheep, liver                       0.200000   1.000     
1.000   

19023540 19B  Spices, other                      0.010000   1.000     
1.000   

19023541 19B  Spices, other-babyfood             0.010000   1.000     
1.000   

04013550 4A   Spinach                            3.000000   1.000     
0.050   

04013551 4A   Spinach-babyfood                   3.000000   1.000     
0.050   

09023560 9B   Squash, summer                     0.500000   1.000     
0.025   

09023561 9B   Squash, summer-babyfood            0.500000   1.000     
0.025   

09023570 9B   Squash, winter                     0.500000   1.000     
0.025   

09023571 9B   Squash, winter-babyfood            0.500000   1.000     
0.025   

95003590 O    Strawberry                         0.600000   1.000     
1.000   

95003591 O    Strawberry-babyfood                0.600000   1.000     
1.000   

95003600 O    Strawberry, juice                  0.600000   1.000     
1.000   

95003601 O    Strawberry, juice-babyfood         0.600000   1.000     
1.000   

01033660 1CD  Sweet potato                       0.010000   1.000     
1.000   

01033661 1CD  Sweet potato-babyfood              0.010000   1.000     
1.000   

04023670 4B   Swiss chard                        3.000000   1.000     
1.000   

10003690 10   Tangerine                          0.500000   1.000     
1.000   

10003700 10   Tangerine, juice                   0.500000   2.300     
1.000   

01033710 1CD  Tanier, corm                       0.010000   1.000     
1.000   

95003720 O    Tea, dried                        50.000000   1.000     
1.000   

95003730 O    Tea, instant                      50.000000   1.000     
1.000   

08003740 8    Tomatillo                          0.200000   1.000     
1.000   

08003750 8    Tomato                             0.200000   1.000     
1.000   

08003751 8    Tomato-babyfood                    0.200000   1.000     
1.000   

08003760 8    Tomato, paste                      0.400000   1.000     
1.000   

08003761 8    Tomato, paste-babyfood             0.400000   1.000     
1.000   

08003770 8    Tomato, puree                      0.200000   3.300     
1.000   

08003771 8    Tomato, puree-babyfood             0.200000   3.300     
1.000   

08003780 8    Tomato, dried                      0.200000  14.300     
1.000   

08003781 8    Tomato, dried-babyfood             0.200000  14.300     
1.000   

08003790 8    Tomato, juice                      0.200000   1.500     
1.000   

50003820 P    Turkey, meat                       0.010000   1.000     
1.000   

50003821 P    Turkey, meat-babyfood              0.010000   1.000     
1.000   

50003830 P    Turkey, liver                      0.050000   1.000     
1.000   

50003831 P    Turkey, liver-babyfood             0.050000   1.000     
1.000   

50003840 P    Turkey, meat byproducts            0.050000   1.000     
1.000   

50003841 P    Turkey, meat byproducts-babyfood   0.050000   1.000     
1.000   

50003850 P    Turkey, fat                        0.010000   1.000     
1.000   

50003851 P    Turkey, fat-babyfood               0.010000   1.000     
1.000   

50003860 P    Turkey, skin                       0.010000   1.000     
1.000   

50003861 P    Turkey, skin-babyfood              0.010000   1.000     
1.000   

01033870 1CD  Turmeric                           0.010000   1.000     
1.000   

05023890 5B   Turnip, greens                     1.200000   1.000     
1.000   

14003910 14   Walnut                             0.100000   1.000     
1.000   

86010000 O    Water, direct, all sources         0.005000   1.000     
1.000   

86020000 O    Water, indirect, all sources       0.005000   1.000     
1.000   

09013990 9A   Watermelon                         0.500000   1.000     
1.000   

09014000 9A   Watermelon, juice                  0.500000   1.000     
1.000   

01034060 1CD  Yam, true                          0.010000   1.000     
1.000   

01034070 1CD  Yam bean                           0.010000   1.000     
1.000   

Attachment 6.	Summary of DEEM-FCID™ Chronic Results

U.S. Environmental Protection Agency                                
Ver. 2.00

DEEM-FCID Chronic analysis for ACETAMIPRID                      (1994-98
data)

Residue file name: C:\Documents and Settings\dmcneill\My
Documents\Actemidprid\PRIADNTacetamipridCT_chronic.R98

                                                     Adjustment factor
#2 used.

Analysis Date 01-12-2010/08:15:46     Residue file dated:
01-12-2010/08:15:02/8

Reference dose (RfD, Chronic) = .071 mg/kg bw/day

COMMENT 1: Acute/Chronic - UFs = 100

========================================================================
=======

                    Total exposure by population subgroup

------------------------------------------------------------------------
-------

                                                    Total Exposure

                                        
-----------------------------------

          Population                         mg/kg             Percent
of   

           Subgroup                       body wt/day             Rfd   
   

--------------------------------------   -------------      
---------------

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   0.002835                 4.0%

U.S. Population (spring season)             0.002861                
4.0%

U.S. Population (summer season)             0.003114                
4.4%

U.S. Population (autumn season)             0.002700                
3.8%

U.S. Population (winter season)             0.002660                
3.7%

Northeast region                            0.002940                
4.1%

Midwest region                              0.002864                
4.0%

Southern region                             0.002639                
3.7%

Western region                              0.003022                
4.3%

Hispanics                                   0.002916                
4.1%

Non-hispanic whites                         0.002817                
4.0%

Non-hispanic blacks                         0.002589                
3.6%

Non-hisp/non-white/non-black                0.003635                
5.1%

All infants (< 1 year)                      0.005206                
7.3%

Nursing infants                             0.002502                
3.5%

Non-nursing infants                         0.006232                
8.8%

Children 1-6  yrs                           0.008045               
11.3%

Children 7-12 yrs                           0.003764                
5.3%

Females 13-19 (not preg or nursing)         0.002017                
2.8%

Females 20+ (not preg or nursing)           0.002107                
3.0%

Females 13-50 yrs                           0.002212                
3.1%

Females 13+ (preg/not nursing)              0.002362                
3.3%

Females 13+ (nursing)                       0.002580                
3.6%

Males 13-19 yrs                             0.002313                
3.3%

Males 20+ yrs                               0.002013                
2.8%

Seniors 55+                                 0.002162                
3.0%

Children 1-2 yrs                            0.010358               
14.6%

Children 3-5 yrs                            0.007296               
10.3%

Children 6-12 yrs                           0.004055                
5.7%

Youth 13-19 yrs                             0.002170                
3.1%

Adults 20-49 yrs                            0.002031                
2.9%

Adults 50+ yrs                              0.002130                
3.0%

Females 13-49 yrs                           0.002057                
2.9%

------------------------------------------------------------------------
-------

Acetamiprid	Dietary Exposure Assessment	DP No.: 309740

 of   NUMPAGES \* arabic \* MERGEFORMAT  28 

Acetamiprid	Dietary Exposure Assessment	DP No.: 372890

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Acetamiprid	Dietary Exposure Assessment	DP No.: 309740

PC Code: 099050		Page›
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Acetamiprid	Dietary Exposure and Risk Assessment	DP No.: 372890

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