UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C.  20460

OFFICE OF   

PREVENTION, PESTICIDES

AND TOXIC SUBSTANCES 

		PC Code No.:	 110008

DP Barcode: D357831

		Date:	June 1, 2009

SUBJECT:	Drinking Water Assessment for IR-4 Registration for Use of
Spinetoram on Pineapple, Spice subgroup 19B,  Pomegranate, Dates, Hops,
and Dried Cones

TO:		Tom Bloem 

		Mary Clock-Rust

		Health and Effects Division

		Laura Nollen

		Registration Division

FROM:	Larry Liu, Environmental Scientist, Ph.D.

		Environmental Fate and Effects Division 

THROUGH:	Mah Shamim, Ph.D., Branch Chief

Environmental Risk Branch V

Environmental Fate and Effects Division 

		The previous drinking water assessment for use of spinetoram on
turfgrass, stone fruit, pome fruit, tree nuts (completed on May 14,
2007) can be used for the currently proposed uses of Delegate WG and
Radiant SC Insecticide on pineapple, spice subgroup 19B, pomegranate,
dates, hops, and died cones. The maximum single application rates and
the yearly/seasonal application rates for the proposed uses are lower
than those used in the drinking water assessment completed on May 14,
2007.  The proposed uses and application rates in the IR4 registration
are provided in Table 1.

Attached is the previous drinking water assessment on turfgrass, stone
fruit, pome fruit, tree nuts, etc.

\

Table 1.  Uses and application rates for spinetoram

Crop	Maximum Single

Application Rate

(lb a.i./A)	Maximum Number of

Applications per Season	Minimum

Application Interval (days)	Maximum Application rate per Season

(lb a.i. /A/Season)

Hops/Dried Cones	0.063	5	4	0.305

Dates	0.110	4	7	0.305

Pomegranate	0.110	3	4	0.219

Spices

Including allspice, anise, annatto, black caraway, caper, cinnamon,
mustard, white pepper, etc. 	0.060	5	10	0.305

Pineapple	0.060	6	7	0.305





Uses and application rates for spinetoram (reported in the 2007 review)

Crop	Maximum Single

Application Rate

(lb a.i./A)	Maximum Number of

Applications per Season	Minimum

Application Interval (days)	Maximum Application rate per Season

(lb a.i. spinetoram mixture/A/Season)

Asparagus	0.0625	3	4	0.188

Banana and plantain	0.0859	4	7	0.305

Bulb vegetables	0.0781	5	4	0.234

Bushberries	0.0938	6	6	0.305

Caneberries	0.0938	6	4	0.305

Cereal grains	0.0469	3	4	0.141

Citrus	0.0938	3	7	0.188

Cole crops (brassica vegetables)	0.0781	6	4	0.266

Corn (field and teosinte)	0.0469	3	2	0.125

Corn (sweet, popcorn, corn grown for seed)	0.0469	6	4	0.281

Cotton	0.0625	6	4	0.266

Cranberry	0.0938	6	7	0.305

Cucurbits	0.0781	6	4	0.266

Fig	0.1094	4	7	0.305

Fruiting vegetables and okra	0.0781	6	4	0.266

(It is also a yearly rate if there are more than one growing season in a
year)

Grape	0.0781	5	4	0.305

Herbs and spice	0.0625	5	4	0.305

Leafy vegetables	0.0781	6	4	0.266

Leaves of root, tuber, legume vegetables 	0.0781	6	7	0.266

Legume vegetables (succulent beans and peas)	0.0625	6	4	0.219

Legume vegetables (dried beans and peas)	0.0625	6	3	0.094

Mint	0.0938	4	4	0.305

Peanut	0.0625	3	7	0.188

Pome fruit	0.1094	4	7	0.438

Potatoes, tuberous corn vegetables	0.0625	4	7	0.250

Root vegetables (celeriac, edible burdock, oriental radish, rutabaga,
turnip)	0.0625	3	4	0.188

Root vegetables (carrot + others)	0.0625	4	4	0.219

Soybean	0.0313	4	4	0.109

Stone fruit	0.1094	4	7	0.438

Strawberry	0.0781	5	4	0.305

Tree nuts and pistachios	0.1094	6	7	0.438

Tropical tree fruits	0.1094	3	4	0.219

Tree farms and plantations (non-crop)	0.0859	6	7	0.305

Turf grass typical pests (non-crop)	0.2734	3	7	0.438

Herbaceous and woody ornamentals (non-crop)	0.1531	Not specified

	7	0.438

Commercial aquatic plant production (non-crop)	0.2734	Not specified

	7	0.438

Turf grass fire ant mound treatment (non-crop)	Not specified (spot
treatment of mounds only)	Not specified	Not specified	0.016

Home lawn and garden use  (same rate for all uses)	0.0609	Varies with
crop being treated, number is the same as specified on crop labels
Varies with crop being treated, number is the same as specified on crop
labels	0.367



 UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON D.C., 20460

OFFICE OF 

PREVENTION, PESTICIDES AND 

TOXIC SUBSTANCES

MEMORANDUM	

									DATE:  May 14, 2007

								PC CODE: 110009

								DP BARCODE: 325747

			

SUBJECT:	Tier 1 Estimated Environmental Concentrations of XDE-175 in
Human Health Risk Assessment

TO:	Bonaventure Akinlosotu

	Registration Division

	Thomas Bloem

	RAB1

	Health Effects Division	

FROM:	Larry Liu, Ph.D. Environmental Scientist

ERB5 

Environmental Fate and Effects Division (7507P)

THRU:	Mah Shamim, Ph.D. Branch Chief

ERB5 

Environmental Fate and Effects Division (7507P)

This memo presents the Environmental Fate and Effects Division’s
(EFED) water assessment of the registration of XDE-175 (an insecticide),
for use on turfgrass, stone fruit, pome fruit, tree nuts, etc. in the
human health risk assessment.

The estimates for drinking water were performed using the model FIRST
for surface water and SCIGROW for ground water and were based on a
combined maximum yearly application rate for turfgrass.  According to
the labels, XDE-175 can be applied under two conditions in turfgrass. 
The first condition is that XDE-175 can be applied to turfgrass to
control typical insect pests at a maximum yearly rate of 0.438 lb ai/A. 
The second condition is that it can also be applied to control fire ants
at a maximum yearly rate of 0.016 lb ai/A in the same turfgrass. 
Therefore, a combined maximum yearly rate of 0.454 lb ai/A (0.438 lb
ai/A for turf pests + 0.016 lb ai/A for fire ants) was used in modeling.
 The environmental fate information for this chemical is relatively
complete.  Since degradates that were either identified or partially
identified in the fate studies still contain the major ring structures
of the parent compound, the total residue method was used in modeling. 
The maximum expected concentration of XDE-175 in surface waters is
14.419 ppb for acute risk calculations and 6.171 ppb for chronic risk
and cancer risk calculations.  Concentrations in ground water are not
expected to exceed 0.072 ppb (see table below).

Estimated Tier 1 concentrations of XDE-175 in drinking water.

           Chemical

           	

	       Surface Water (ug/L)

	

 Groundwater (ug/L)

	

Acute	

Chronic	

Acute and Chronic



       XDE-175	

14.419	

6.171

   	

     0.072        

       



Should the results of this assessment indicate a need for further
refinement, please, contact us as soon as possible so that we may
schedule a Tier II assessment.

Drinking Water Assessment

Since the registrant has not submitted any monitoring studies to support
the registration of XDE-175, the drinking water and surface water
exposure assessment herein is only based on modeling results.  The
assumption of this Tier I Screening Level exposure assessment is that
100% of the applied chemical is expected to be available for runoff.   

a.  Surface Water Modeling

The FIRST model was used to estimate concentrations that might occur in
vulnerable surface waters.  FIRST is a new screening model designed to
estimate the pesticide concentrations found in water for use in drinking
water assessments.  It provides high-end values on the concentrations
that might be found in a small drinking water reservoir due to the use
of pesticide.  Like GENEEC, the model previously used for Tier I
screening level, FIRST is a single-event model (one run-off event), but
can account for spray drift from multiple applications.  FIRST uses a
Drinking Water Reservoir instead of a pond as the standard scenario. 
The FIRST scenario includes a 427 acres field immediately adjacent to a
13 acres reservoir, 9 feet deep, with continuous flow (two turnovers per
year).  The pond receives a spray drift event from each application plus
one runoff event.  The runoff event moves a maximum of 8% of the applied
pesticide into the pond.  This amount can be reduced due to degradation
on field and the effect of binding to soil.  Spray drift is equal to
6.4% of the applied concentration from the ground spray application and
16% for aerial applications.

FIRST also makes adjustments for the percent crop area. While FIRST
assumes that the entire watershed would not be treated, the use of a PCA
is still a screen because it represents the highest percentage of crop
cover of any large watershed in the US, and it assumes that the entire
crop is being treated.  Various other conservative assumptions of FIRST
include the use of a small drinking water reservoir surrounded by a
runoff-prone watershed, the use of the maximum use rate, no buffer zone,
and a single large rainfall.

b.    SEQ CHAPTER \h \r 1 Background Information on SCIGROW:

SCIGROW is a screening model used by the EPA Office of Pesticide
Programs (OPP) to estimate pesticide concentrations in vulnerable ground
water. The model provides an exposure value that is used to determine
the potential risk to the environment and to human health from drinking
water contaminated with the pesticide. The SCIGROW estimate is based on
environmental fate properties of the pesticide (aerobic soil degradation
half-life and linear adsorption coefficient normalized for soil organic
carbon content), the maximum application rate, and existing data from
small-scale prospective ground-water monitoring studies at sites with
sandy soils and shallow ground water.

Pesticide concentrations estimated by SCIGROW represent conservative or
high-end exposure values because the model is based on ground-water
monitoring studies which were conducted by applying pesticides at
maximum allowed rates and frequency to vulnerable sites (i.e., shallow
aquifers, sandy, permeable soils, and substantial rainfall and/or
irrigation to maximize leaching). In most cases, a large majority of the
use areas will have ground water that is less vulnerable to
contamination than the areas used to derive the SCIGROW estimate. 

The SCIGROW value is likely to be exceeded only under exceptional
circumstances in a small percentage of the use area. No more than a few
percent of U.S. agricultural land consists of sandy soils overlying
shallow ground water like those selected for reasonable worst-case,
small-scale prospective groundwater monitoring studies.

c.  Modeling Input Parameters

Table 1 and Table 2 summarize the input values used in the model runs
for FIRST and SCIGROW, respectively.  Fate parameters were obtained from
studies submitted by the registrant and modified, if necessary,
according to the Guidance for Selecting Input Parameters in Modeling the
Environmental Fate and Transport of Pesticides, Version ll (February 28,
2002).  Since degradates that were either identified or partially
identified in the fate studies still contain the major ring structures
of the parent compound, the total residue method was used in modeling.
Attached to this memo are copies of the original printouts generated
from FIRST and SCIGROW runs.       

Table 1. Input Parameters for RIRST Model.

Parameter	

Input	

Source

Crop	Turfgrass	Label

Water solubility (ppm)	11.3	MRID 46695004

Aqueous photolysis t1/2 (days)	Stable	MRID 46695023



Hydrolysis t1/2 @ pH 7 (days)	

Stable	

MRID 46695022



Aerobic soil t1/2 (days)	

Stable	

MRID 46695025



Aerobic aquatic t1/2 (days) 	

Stable	

MRID 46695026

Organic carbon partition coefficient – the lowest non-sand Koc (mL/g)	

2344	

MRID 46695028

Pesticide is Wetted-In	No	Label

PCA	1	Label

Depth of Incorporation (inches)	0	Label

Maximum Application rate per season (the seasonal maximum rate was used
in the modeling; lb a.i./Acre)	0.454 lb a.i./acre	

Label 

Applications/year	1	Label 



Table 2. Input Parameters for SCIGROW Model.

Parameter	

Input	

Source



Aerobic soil t1/2 (days)	

Stable	

MRID 46695025

Organic carbon partition coefficient – the lowest Koc (mL/g)	

1800	

MRID 46695028

Maximum Application rate per season (the seasonal maximum rate was used
in the modeling; lb a.i./Acre)	0.454 lb a.i./acre	

Label 

Applications/year	1	Label 



Modeling Results

Estimated Tier I concentrations of XDE-175 in vulnerable surface water
were  

14.419 ppb for acute exposure and up to 6.171 ppb for chronic exposure. 
Estimated acute and chronic exposure to XDE-175 from vulnerable
groundwater is 0.072 ppb (Table 3)

Table 3.  Modeling Results for Use of XDE-175.

Parameter	Values

FIRST Peak Untreated Water Concentration (ppb)	14.419

FIRST Annual Average Untreated Water Concentration (ppb)	6.171

SCIGROW Ground Water Concentration (ppb)	0.072



Attachments

First Output:

   RUN No. 111 FOR XDE-175          ON   turfgrass     * INPUT VALUES * 

   --------------------------------------------------------------------

    RATE (#/AC)   No.APPS &   SOIL  SOLUBIL  APPL TYPE  %CROPPED INCORP

     ONE(MULT)    INTERVAL    Koc   (PPM )   (%DRIFT)     AREA    (IN)

   --------------------------------------------------------------------

   .454(   .454)   1   1    2344.0   11.3   AERIAL(16.0) 100.0    .0

   FIELD AND RESERVOIR HALFLIFE VALUES (DAYS) 

   --------------------------------------------------------------------

   METABOLIC  DAYS UNTIL  HYDROLYSIS   PHOTOLYSIS   METABOLIC  COMBINED

    (FIELD)  RAIN/RUNOFF  (RESERVOIR)  (RES.-EFF)   (RESER.)   (RESER.) 

   --------------------------------------------------------------------

       .00        2          N/A       .00-     .00      .00       .00

   UNTREATED WATER CONC (MICROGRAMS/LITER (PPB)) Ver 1.1.0  JAN 1, 2007

   --------------------------------------------------------------------

        PEAK DAY   (ACUTE)                  ANNUAL AVERAGE (CHRONIC)

		CONCENTRATION				CONCENTRATION

   ---------------------------------------------------------------------

		   14.419					    6.171

      

SCIGROW Output (version 2.3):

 chemical: XDE-175

 time is  5/ 3/2007  11:50:58

 -----------------------------------------------------------------------
-

  Application      Number of       Total Use    Koc      Soil Aerobic

  rate (lb/acre)  applications   (lb/acre/yr)  (ml/g)   metabolism
(days)

 -----------------------------------------------------------------------
-

      0.454           1.0           0.454      1.80E+03     1000.0

 -----------------------------------------------------------------------
-

 groundwater screening conc (ppb) =   7.2E-02 

 PAGE  1 

