  SEQ CHAPTER \h \r 1                                UNITED STATES
ENVIRONMENTAL PROTECTION AGENCY

                                                            WASHINGTON,
D.C. 20460

			

	OFFICE OF PREVENTION, PESTICIDES AND

		TOXIC SUBSTANCES

  January 8, 2009

PC Code:     288201

	DP Barcodes: D353180

MEMORANDUM 

SUBJECT:	Tier II Drinking Water Concentrations (Surface and Ground
Water) of the Combined Residues of the Fungicide Pyrimethanil (CAS #
53112-28-0) and the Major Metabolite, 2-Amino-4,6-dimethylpyrimidine
(CAS # 767-15-7).

TO:		Susan Stanton, Risk Manager Reviewer

Risk Integration, Minor Use & Emergency Response Branch

		Registration Division (7505C)

FROM:	Mark Corbin, Senior Environmental Scientist

		Environmental Risk Branch III

Environmental Fate and Effects Division (7507C)

THRU:	Dana Spatz, Branch Chief

		Environmental Risk Branch III

Environmental Fate and Effects Division (7507C)

This memo presents Tier 2 Estimated Drinking Water Concentrations
(EDWCs) for the combined residues of the fungicide pyrimethanil
(4,6-dimethyl-N-phenyl-2-pyrimidinamine) and its major metabolite
(2-amino-4,6-dimethylpyrimidine), for the proposed new uses, based on a
maximum annual application rate of 0.75 lbs. a.i./acre.  The models,
PRZM, EXAMS and SCIGROW were used in estimating EDWCs derived from
surface water and groundwater, respectively.  This memo draws on the
previous new use assessment completed in October 22, 2003 (DP 283999)
that assessed pyrimethanil uses on grapes, nuts, onions, plums, and
strawberries.  The current assessment covers lemons and summarizes the
EDWC’s from the previous assessment.  No new data have been submitted
since the previous assessment and therefore detail on the environmental
fate profile of pyrimethanil may be found in that assessment.  Table 1
summarizes the surface water EDWC from both the previous assessment and
this current assessment.  For purposes of this assessment the highest
EDWC are from the previous assessment for use on strawberries.

Table 1: PCA Corrected PRZM/EXAMS Tier II Concentration Values for
Combined Total Residues, Parent (Pyrimethanil) Plus Major Degradate
(2-Amino-4,6-dimethylpyrimidine) for the Proposed New Uses

Standard Crop Scenario (Regional Percent Cropped Area, PCA)	Acute
Exposure from  One in Ten Year Peak Values (ppb)	Non-Cancer Chronic
Exposure  from One in Ten Year Annual Mean (ppb)	Average of Yearly
Average for Cancer Exposure (ppb)

	PCA Corrected	PCA Corrected	PCA Corrected

Previously Registered Uses

CA grapes (56%)	7.0	2.6	2.2

OR nuts (63%)	14.4	4.7	2.4

GA onion (38%)	23.3	4.0	2.8

CA plums (56%)	6.2	2.3	1.5

FL strawberry (38%)	37.8	5.1	3.7

Proposed New Uses

CA citrus (56%)	1.8	1.0	0.8

Fl citrus (38%)	21.9	2.8	1.6

TX citrus (67%)	9.7	3.5	1.6



The current proposed use pattern yields a lower annual total load than
the previously assessed uses and thus the EDWC for ground water from the
previous assessment should be used for this evaluation.  The Tier 1
SCIGROW generated EDWC value derived  for groundwater  from the combined
residues is 4.8 μg/L.  This value is recommended for use for both acute
and chronic exposures.  

ATTACHMENT A

MODEL OUTPUT

stored as TX citrus.out





Chemical: pyrimethanil





PRZM environment: STXgrapefruitNMC.txt	modified Thuday, 14 June 2007 at
09:17:40



EXAMS environment: ir298.exv	modified Thuday, 29 August 2002 at 14:34:12

	Metfile: w12919.dvf	modified Wedday, 3 July 2002 at 08:06:24



Water segment concentrations (ppb)











	Year	Peak	96 hr	21 Day	60 Day	90 Day	Yearly

1961	5.707	5.616	5.255	4.519	4.033	1.903

1962	5.089	5.002	4.657	3.991	3.59	2.046

1963	6.79	6.675	6.214	5.564	5.141	2.649

1964	2.787	2.746	2.584	2.289	2.138	1.276

1965	2.132	2.102	1.982	1.73	1.573	0.9394

1966	9.07	8.927	8.352	7.241	6.495	3.073

1967	2.929	2.885	2.711	2.346	2.096	1.308

1968	2.756	2.707	2.588	2.302	2.068	1.234

1969	10.03	9.86	9.337	7.972	7.059	3.245

1970	3.723	3.678	3.447	3.109	3.004	1.913

1971	5.145	5.061	4.726	4.222	3.878	2.018

1972	2.471	2.443	2.302	2.17	2.088	1.361

1973	2.872	2.835	2.646	2.265	2.035	1.343

1974	5.302	5.21	4.844	4.125	3.708	2.144

1975	2.659	2.618	2.45	2.114	1.894	1.18

1976	3.264	3.212	3.052	2.863	2.682	1.459

1977	29.02	28.56	26.69	22.77	20.31	8.756

1978	5.399	5.316	4.982	4.405	4.317	2.673

1979	4.413	4.343	4.056	3.493	3.174	1.777

1980	4.427	4.359	4.045	3.43	3.076	1.742

1981	16.67	16.43	15.55	13.49	12.17	5.731

1982	14.48	14.24	13.71	12.38	11.08	5.239

1983	3.617	3.567	3.367	2.956	2.675	1.65

1984	14.32	14.07	13.08	11.32	10.15	4.524

1985	4.183	4.114	3.834	3.495	3.16	2.251

1986	2.451	2.415	2.272	1.977	1.787	1.074

1987	2.107	2.079	1.962	1.89	1.811	1.006

1988	2.097	2.065	1.937	1.747	1.591	0.7811

1989	8.553	8.413	7.819	6.643	5.922	2.753

1990	2.862	2.817	2.635	2.483	2.377	1.316









Sorted results





	Prob.	Peak	96 hr	21 Day	60 Day	90 Day	Yearly

0.032258	29.02	28.56	26.69	22.77	20.31	8.756

0.064516	16.67	16.43	15.55	13.49	12.17	5.731

0.096774	14.48	14.24	13.71	12.38	11.08	5.239

0.129032	14.32	14.07	13.08	11.32	10.15	4.524

0.16129	10.03	9.86	9.337	7.972	7.059	3.245

0.193548	9.07	8.927	8.352	7.241	6.495	3.073

0.225806	8.553	8.413	7.819	6.643	5.922	2.753

0.258065	6.79	6.675	6.214	5.564	5.141	2.673

0.290323	5.707	5.616	5.255	4.519	4.317	2.649

0.322581	5.399	5.316	4.982	4.405	4.033	2.251

0.354839	5.302	5.21	4.844	4.222	3.878	2.144

0.387097	5.145	5.061	4.726	4.125	3.708	2.046

0.419355	5.089	5.002	4.657	3.991	3.59	2.018

0.451613	4.427	4.359	4.056	3.495	3.174	1.913

0.483871	4.413	4.343	4.045	3.493	3.16	1.903

0.516129	4.183	4.114	3.834	3.43	3.076	1.777

0.548387	3.723	3.678	3.447	3.109	3.004	1.742

0.580645	3.617	3.567	3.367	2.956	2.682	1.65

0.612903	3.264	3.212	3.052	2.863	2.675	1.459

0.645161	2.929	2.885	2.711	2.483	2.377	1.361

0.677419	2.872	2.835	2.646	2.346	2.138	1.343

0.709677	2.862	2.817	2.635	2.302	2.096	1.316

0.741935	2.787	2.746	2.588	2.289	2.088	1.308

0.774194	2.756	2.707	2.584	2.265	2.068	1.276

0.806452	2.659	2.618	2.45	2.17	2.035	1.234

0.83871	2.471	2.443	2.302	2.114	1.894	1.18

0.870968	2.451	2.415	2.272	1.977	1.811	1.074

0.903226	2.132	2.102	1.982	1.89	1.787	1.006

0.935484	2.107	2.079	1.962	1.747	1.591	0.9394

0.967742	2.097	2.065	1.937	1.73	1.573	0.7811









0.1	14.464	14.223	13.647	12.274	10.987	5.1675





	Average of yearly averages:	2.345483









	9.7	9.5	9.1	8.2	7.4	3.5







1.6









Inputs generated by pe5.pl - Novemeber 2006











Data used for this run:





Output File: TX citrus





	Metfile:	w12919.dvf





PRZM scenario:	STXgrapefruitNMC.txt



	EXAMS environment file:	ir298.exv





	Chemical Name:	pyrimethanil





Description	Variable Name	Value	Units	Comments

	Molecular weight	mwt	199.26	g/mol



	Henry's Law Const.	henry

atm-m^3/mol



Vapor Pressure	vapr	0.000226	torr



	Solubility	sol	121	mg/L



	Kd	Kd	2.85	mg/L



	Koc	Koc

mg/L



	Photolysis half-life	kdp	0	days	Half-life



Aerobic Aquatic Metabolism	kbacw	207	days	Halfife



Anaerobic Aquatic Metabolism	kbacs	1092	days	Halfife



Aerobic Soil Metabolism	asm	263	days	Halfife



Hydrolysis:	pH 4	0	days	Half-life



Hydrolysis:	pH 7	0	days	Half-life



Hydrolysis:	pH 9	0	days	Half-life



Method:	CAM	1	integer	See PRZM manual

	Incorporation Depth:	DEPI	0	cm



	Application Rate:	TAPP	0.78	kg/ha



	Application Efficiency:	APPEFF	0.95	fraction



	Spray Drift	DRFT	0.064	fraction of application rate applied to pond

Application Date	Date	3-Jan	dd/mm or dd/mmm or dd-mm or dd-mmm

Record 17:	FILTRA







IPSCND	1





	UPTKF





	Record 18:	PLVKRT







PLDKRT







FEXTRC	0.5





Flag for Index Res. Run	IR	Reservoir





Flag for runoff calc.	RUNOFF	total	none, monthly or total(average of
entire run)





stored as FL citrus.out





Chemical: pyrimethanil





PRZM environment: FLcitrusSTD.txt	modified Tueday, 29 May 2007 at
11:45:56



EXAMS environment: ir298.exv	modified Thuday, 29 August 2002 at 14:34:12

	Metfile: w12844.dvf	modified Wedday, 3 July 2002 at 08:04:30



Water segment concentrations (ppb)











	Year	Peak	96 hr	21 Day	60 Day	90 Day	Yearly

1961	20.2	19.46	18.02	14.27	10.9	2.689

1962	6.612	6.392	5.57	4.176	3.43	1.817

1963	17.18	16.55	14.25	11.32	8.983	2.671

1964	94.72	91.22	81.79	61.65	48.3	12.81

1965	108	104	91.15	68.46	52.78	17.07

1966	28.15	27.22	23.74	17.8	14.62	7.335

1967	18.79	18.1	15.58	11.65	8.665	3.239

1968	29.99	28.9	26.24	20.03	15.32	4.752

1969	23.68	22.82	21.38	16.66	12.82	4.727

1970	7.742	7.493	6.554	4.948	4.073	1.742

1971	7.881	7.709	7.2	5.833	4.66	1.346

1972	59.36	57.24	49.3	34.58	23.43	6.218

1973	22.22	21.48	18.72	14.03	11.5	4.19

1974	14.62	14.1	12.24	9.914	7.833	2.413

1975	5.124	4.95	4.297	3.334	2.695	1.505

1976	18.88	18.22	15.79	14.27	11.55	3.144

1977	12.91	12.51	11.05	7.17	5.178	2.443

1978	17.13	16.66	14.55	11.65	8.746	3.306

1979	14.47	13.94	11.98	8.977	7.001	2.795

1980	5.62	5.436	4.94	4.455	3.69	1.554

1981	24.11	23.27	20.11	14.65	10.67	3.101

1982	42.41	40.95	38.1	28.78	19.94	6.605

1983	16.15	15.63	13.65	10.24	8.407	4.423

1984	21.15	20.59	17.9	14.39	10.38	3.298

1985	10.56	10.22	8.926	6.708	5.505	2.507

1986	21.98	21.34	18.65	13.79	10.56	3.42

1987	39.92	38.83	33.65	30.29	24.21	6.974

1988	16.21	15.62	13.59	10.11	7.304	4.111

1989	19.63	18.93	16.33	13.61	10.87	3.645

1990	9.412	9.059	7.761	5.747	4.62	2.176









Sorted results





	Prob.	Peak	96 hr	21 Day	60 Day	90 Day	Yearly

0.032258	108	104	91.15	68.46	52.78	17.07

0.064516	94.72	91.22	81.79	61.65	48.3	12.81

0.096774	59.36	57.24	49.3	34.58	24.21	7.335

0.129032	42.41	40.95	38.1	30.29	23.43	6.974

0.16129	39.92	38.83	33.65	28.78	19.94	6.605

0.193548	29.99	28.9	26.24	20.03	15.32	6.218

0.225806	28.15	27.22	23.74	17.8	14.62	4.752

0.258065	24.11	23.27	21.38	16.66	12.82	4.727

0.290323	23.68	22.82	20.11	14.65	11.55	4.423

0.322581	22.22	21.48	18.72	14.39	11.5	4.19

0.354839	21.98	21.34	18.65	14.27	10.9	4.111

0.387097	21.15	20.59	18.02	14.27	10.87	3.645

0.419355	20.2	19.46	17.9	14.03	10.67	3.42

0.451613	19.63	18.93	16.33	13.79	10.56	3.306

0.483871	18.88	18.22	15.79	13.61	10.38	3.298

0.516129	18.79	18.1	15.58	11.65	8.983	3.239

0.548387	17.18	16.66	14.55	11.65	8.746	3.144

0.580645	17.13	16.55	14.25	11.32	8.665	3.101

0.612903	16.21	15.63	13.65	10.24	8.407	2.795

0.645161	16.15	15.62	13.59	10.11	7.833	2.689

0.677419	14.62	14.1	12.24	9.914	7.304	2.671

0.709677	14.47	13.94	11.98	8.977	7.001	2.507

0.741935	12.91	12.51	11.05	7.17	5.505	2.443

0.774194	10.56	10.22	8.926	6.708	5.178	2.413

0.806452	9.412	9.059	7.761	5.833	4.66	2.176

0.83871	7.881	7.709	7.2	5.747	4.62	1.817

0.870968	7.742	7.493	6.554	4.948	4.073	1.742

0.903226	6.612	6.392	5.57	4.455	3.69	1.554

0.935484	5.62	5.436	4.94	4.176	3.43	1.505

0.967742	5.124	4.95	4.297	3.334	2.695	1.346









0.1	57.665	55.611	48.18	34.151	24.132	7.2989





	Average of yearly averages:	4.267533









	21.9	21.1	18.3	13	9.2	2.8







1.6









Inputs generated by pe5.pl - Novemeber 2006











Data used for this run:





Output File: FL citrus





	Metfile:	w12844.dvf





PRZM scenario:	FLcitrusSTD.txt





EXAMS environment file:	ir298.exv





	Chemical Name:	pyrimethanil





Description	Variable Name	Value	Units	Comments

	Molecular weight	mwt	199.26	g/mol



	Henry's Law Const.	henry

atm-m^3/mol



Vapor Pressure	vapr	0.000226	torr



	Solubility	sol	121	mg/L



	Kd	Kd	2.85	mg/L



	Koc	Koc

mg/L



	Photolysis half-life	kdp	0	days	Half-life



Aerobic Aquatic Metabolism	kbacw	207	days	Halfife



Anaerobic Aquatic Metabolism	kbacs	1092	days	Halfife



Aerobic Soil Metabolism	asm	263	days	Halfife



Hydrolysis:	pH 4	0	days	Half-life



Hydrolysis:	pH 7	0	days	Half-life



Hydrolysis:	pH 9	0	days	Half-life



Method:	CAM	1	integer	See PRZM manual

	Incorporation Depth:	DEPI	0	cm



	Application Rate:	TAPP	0.78	kg/ha



	Application Efficiency:	APPEFF	0.95	fraction



	Spray Drift	DRFT	0.064	fraction of application rate applied to pond

Application Date	Date	10-Nov	dd/mm or dd/mmm or dd-mm or dd-mmm

Record 17:	FILTRA







IPSCND	1





	UPTKF





	Record 18:	PLVKRT







PLDKRT







FEXTRC	0.5





Flag for Index Res. Run	IR	Reservoir





Flag for runoff calc.	RUNOFF	total	none, monthly or total(average of
entire run)





stored as CA citrus.out





Chemical: pyrimethanil





PRZM environment: CAcitrus_WirrigSTD.txt	modified Tueday, 29 May 2007 at
11:41:26



EXAMS environment: ir298.exv	modified Thuday, 29 August 2002 at 14:34:12

	Metfile: w23155.dvf	modified Wedday, 3 July 2002 at 08:04:20



Water segment concentrations (ppb)











	Year	Peak	96 hr	21 Day	60 Day	90 Day	Yearly

1961	1.822	1.809	1.757	1.643	1.556	0.8482

1962	2.289	2.274	2.212	2.073	1.964	1.175

1963	2.502	2.485	2.414	2.348	2.266	1.422

1964	2.747	2.73	2.66	2.514	2.391	1.477

1965	3.478	3.453	3.352	3.14	2.972	1.825

1966	2.788	2.769	2.694	2.522	2.384	1.491

1967	2.581	2.564	2.494	2.354	2.248	1.387

1968	2.797	2.778	2.7	2.563	2.444	1.493

1969	2.643	2.627	2.559	2.424	2.305	1.411

1970	2.504	2.487	2.418	2.268	2.148	1.276

1971	2.435	2.417	2.348	2.195	2.079	1.24

1972	2.431	2.412	2.338	2.175	2.051	1.215

1973	2.416	2.399	2.34	2.237	2.116	1.242

1974	5.551	5.511	5.347	4.982	4.697	2.657

1975	3.23	3.209	3.119	2.936	2.792	1.783

1976	2.661	2.642	2.568	2.406	2.276	1.384

1977	2.529	2.512	2.434	2.378	2.275	1.362

1978	2.615	2.596	2.521	2.421	2.324	1.406

1979	2.538	2.522	2.454	2.303	2.18	1.313

1980	2.602	2.586	2.518	2.394	2.284	1.409

1981	2.646	2.63	2.556	2.491	2.395	1.457

1982	2.668	2.648	2.57	2.495	2.412	1.484

1983	2.746	2.728	2.655	2.51	2.391	1.483

1984	2.593	2.576	2.507	2.358	2.241	1.381

1985	2.543	2.527	2.464	2.325	2.209	1.362

1986	2.579	2.562	2.518	2.383	2.267	1.404

1987	2.572	2.555	2.486	2.33	2.205	1.365

1988	2.785	2.761	2.674	2.472	2.319	1.326

1989	2.379	2.358	2.276	2.095	1.959	1.128

1990	2.309	2.289	2.207	2.04	1.91	1.08









Sorted results





	Prob.	Peak	96 hr	21 Day	60 Day	90 Day	Yearly

0.032258	5.551	5.511	5.347	4.982	4.697	2.657

0.064516	3.478	3.453	3.352	3.14	2.972	1.825

0.096774	3.23	3.209	3.119	2.936	2.792	1.783

0.129032	2.797	2.778	2.7	2.563	2.444	1.493

0.16129	2.788	2.769	2.694	2.522	2.412	1.491

0.193548	2.785	2.761	2.674	2.514	2.395	1.484

0.225806	2.747	2.73	2.66	2.51	2.391	1.483

0.258065	2.746	2.728	2.655	2.495	2.391	1.477

0.290323	2.668	2.648	2.57	2.491	2.384	1.457

0.322581	2.661	2.642	2.568	2.472	2.324	1.422

0.354839	2.646	2.63	2.559	2.424	2.319	1.411

0.387097	2.643	2.627	2.556	2.421	2.305	1.409

0.419355	2.615	2.596	2.521	2.406	2.284	1.406

0.451613	2.602	2.586	2.518	2.394	2.276	1.404

0.483871	2.593	2.576	2.518	2.383	2.275	1.387

0.516129	2.581	2.564	2.507	2.378	2.267	1.384

0.548387	2.579	2.562	2.494	2.358	2.266	1.381

0.580645	2.572	2.555	2.486	2.354	2.248	1.365

0.612903	2.543	2.527	2.464	2.348	2.241	1.362

0.645161	2.538	2.522	2.454	2.33	2.209	1.362

0.677419	2.529	2.512	2.434	2.325	2.205	1.326

0.709677	2.504	2.487	2.418	2.303	2.18	1.313

0.741935	2.502	2.485	2.414	2.268	2.148	1.276

0.774194	2.435	2.417	2.348	2.237	2.116	1.242

0.806452	2.431	2.412	2.34	2.195	2.079	1.24

0.83871	2.416	2.399	2.338	2.175	2.051	1.215

0.870968	2.379	2.358	2.276	2.095	1.964	1.175

0.903226	2.309	2.289	2.212	2.073	1.959	1.128

0.935484	2.289	2.274	2.207	2.04	1.91	1.08

0.967742	1.822	1.809	1.757	1.643	1.556	0.8482









0.1	3.1867	3.1659	3.0771	2.8987	2.7572	1.754





	Average of yearly averages:	1.40954









	1.8	1.8	1.7	1.6	1.5	1







0.8









Inputs generated by pe5.pl - Novemeber 2006











Data used for this run:





Output File: CA citrus





Metfile:	w23155.dvf





PRZM scenario:	CAcitrus_WirrigSTD.txt



	EXAMS environment file:	ir298.exv





	Chemical Name:	pyrimethanil





Description	Variable Name	Value	Units	Comments

	Molecular weight	mwt	199.26	g/mol



	Henry's Law Const.	henry

atm-m^3/mol



Vapor Pressure	vapr	0.000226	torr



	Solubility	sol	121	mg/L



	Kd	Kd	2.85	mg/L



	Koc	Koc

mg/L



	Photolysis half-life	kdp	0	days	Half-life



Aerobic Aquatic Metabolism	kbacw	207	days	Halfife



Anaerobic Aquatic Metabolism	kbacs	1092	days	Halfife



Aerobic Soil Metabolism	asm	263	days	Halfife



Hydrolysis:	pH 4	0	days	Half-life



Hydrolysis:	pH 7	0	days	Half-life



Hydrolysis:	pH 9	0	days	Half-life



Method:	CAM	1	integer	See PRZM manual

	Incorporation Depth:	DEPI	0	cm



	Application Rate:	TAPP	0.78	kg/ha



	Application Efficiency:	APPEFF	0.95	fraction



	Spray Drift	DRFT	0.064	fraction of application rate applied to pond

Application Date	Date	3-Jan	dd/mm or dd/mmm or dd-mm or dd-mmm

Record 17:	FILTRA







IPSCND	1





	UPTKF





	Record 18:	PLVKRT







PLDKRT







FEXTRC	0.5





Flag for Index Res. Run	IR	Reservoir





Flag for runoff calc.	RUNOFF	total	none, monthly or total(average of
entire run)



ATTACHMENT B

PREVIOUS ASSESSMENT



  SEQ CHAPTER \h \r 1                                UNITED STATES
ENVIRONMENTAL PROTECTION AGENCY

                                                            WASHINGTON,
D.C. 20460

			

	OFFICE OF PREVENTION, PESTICIDES AND

		TOXIC SUBSTANCES

  October 22, 2003

PC Code:     288201

	DP Barcodes: D283999 

											        D290313

MEMORANDUM 

SUBJECT:	Tier II Drinking Water Concentrations (Surface and Ground
Water) of the Combined Residues of the Fungicide Pyrimethanil (CAS #
53112-28-0) and the Major Metabolite, 2-Amino-4,6-dimethylpyrimidine
(CAS # 767-15-7).

TO:		Dana Vogel, Team Leader

		RAB 1

		Health Effects Division (7509C)

FROM:	Lucy Shanaman, Chemist

		Environmental Risk Branch III

Environmental Fate and Effects Division (7507C)

		James Wolf, Soil Scientist

		Environmental Risk Branch III

Environmental Fate and Effects Division (7507C)

THRU:	Ben Smith, Branch Chief

		Environmental Risk Branch III

Environmental Fate and Effects Division (7507C)

CC:		Mary Waller, PM Team 21

		Registration Division (7505C) 

37.8 μg/L from use of pyrimethanil on Florida strawberries.  The
maximum  estimated annual mean non-cancer chronic exposure concentration
for the combined residues (adjusted for regional percent cropped area)
is 5.1 μg/L from use of pyrimethanil on Florida strawberries.  The
maximum estimated cancer chronic exposure concentration for the combined
residues (adjusted for regional percent cropped area) is 3.7 μg/L from
use of pyrimethanil on Florida strawberries.  The chronic cancer value
represents the mean annual value over a 30-year period, while acute and
non-cancer chronic values represent ninetieth percentiles.  Results for
the combined residues of the five new uses are presented below in Table
1.  For comparison purposes, modeling results for parent only are
appended to this assessment.

4.8 μg/L.  This value is recommended for use for both acute and chronic
exposures.  

	Pyrimethanil is expected to have low mobility in the environment.  The
major pyrimethanil metabolite, on the other hand, is expected to be
moderately mobile in the environment.  All of the mobility data
submitted for the metabolite, and nine out of the eleven Kd values
submitted for the parent compound, were determined using foreign soils. 
USDA Taxonomic Classification System citations were not provided for
these foreign soils, and it could not be determined if these soils are
representative of soils found in the proposed use areas.  Should the
drinking water concentrations estimated here approach levels of concern,
making it necessary to refine this assessment, then more data may be
required to represent the soils found in use areas within the United
States.  Additionally, EFED has no data regarding the mobility of the
combined parent / metabolite residues.  

	Aerobic degradation is expected to be the major route of dissipation
for pyrimethanil in the environment.  The major pyrimethanil metabolite
modeled here is expected to be more resistant to aerobic degradation
than the parent compound.  However, data are not available to
characterize other possible degradation pathways for the metabolite.  

	A report has also been submitted by Bayer Crop Science titled,
“Refined Acute and Chronic Dietary Exposure Analysis for Pyrimethanil
Including Drinking Water Estimated Concentration (DWEC) Comparison to
Drinking Water Level of Comparison (DWLOC)” (DP Barcode D290313). 
However, this report is of limited value with regards to this drinking
water assessment.  While the drinking water concentrations reported were
based on the more conservative Tier 1 assessment, input values used were
obtained from submitted study reports and not from the EFED reviewed
Data Evaluation Reports.  Further, the input values used in the
submitted assessment were not chosen in accordance with Agency policy

( http://www.epa.gov/oppefed1/models/water/input_guidance2_28_02.htm ;
if Koc shows greater than a three-fold variation, use the lowest value).

Table 1: PCA Corrected PRZM/EXAMS Tier II Concentration Values for
Combined Total Residues, Parent (Pyrimethanil) Plus Major Degradate
(2-Amino-4,6-dimethylpyrimidine) for the Proposed New Uses

Standard Crop Scenario (Regional Percent Cropped Area, PCA)	Acute
Exposure from  One in Ten Year Peak Values (ppb)	Non-Cancer Chronic
Exposure  from One in Ten Year Annual Mean (ppb)	Average of Yearly
Average for Cancer Exposure (ppb)

	Not  Corrected	PCA Corrected	Not  Corrected	PCA Corrected	Not 
Corrected	PCA Corrected

CAgrapes (56%)	12.5	7.0	4.6	2.6	3.9	2.2

ORnuts (63%)	23.3	14.4	7.0	4.7	3.9	2.4

GAonion (38%)	61.6	23.3	10.5	4.0	7.3	2.8

CAplums (56%)	11.1	6.2	4.1	2.3	2.7	1.5

FLstrawberry (38%)	99.4	37.8	13.3	5.1	9.8	3.7



Models Used

	The Tier 2 drinking water concentrations derived from surface water for
the proposed crop uses were calculated using two models: PRZM version
3.12 (dated May 24, 2001) and EXAMS 2.98.04 (dated July 18, 2002).  Both
models were launched from the shell, PE4.PL (version 1) developed within
EFED, and adopted for use on May 14, 2003.  The linked PRZM (3.12), and
EXAMS (2.98.5) model (PRZM/EXAMS) is typically used by EFED to simulate
the transport of the pesticide off the field and to estimate pesticides
concentrations in surface waters.  PRZM is employed to evaluate runoff
and spray drift loading to a  receiving surface water body, and EXAMS
uses algorithms to the estimate pesticide concentrations after the
residues reach surface water, by taking into account the different
dissipation mechanism in the aqueous and sediment phases.

	Tier 1 drinking water concentrations derived from groundwater for the
proposed crop uses were calculated using the model, SCIGROW (version
2.3) dated July 29, 2003.  

Background Information on PRZM/EXAMS 

	PRZM (3.12) is a one-dimensional finite-difference modeling system that
was originally developed to model nitrogen soil kinetic processes and
groundwater environment. It was later enhanced to expand its capability
to predict pesticides transport and transformation down through the crop
zone and saturated zone. The expanded capabilities cover additional
phenomena such as soil temperature simulation, microbial transformation,
vapor phase transport in soils, volatilization, irrigation simulation,
and a method of characteristics algorithm to eliminate numerical
dispersion.  The model can also simulate the fate of two parent and two
daughter products and can be used in evaluating leaching and runoff.

	EXAMS (2.98.04) is a model that has a set of process modules that link
fundamental chemical properties to limnological processes that control
the kinetics and transport of chemicals in aquatic systems. It provides
facilities for steady state or long-term evaluation of chronic chemical
discharges, initial-value approaches for studying short-term contaminant
releases, and full kinetic simulations that allow for monthly variation
in mean climatological factors, and changes in contaminant loadings on
daily time scales. It is a relatively complex model that requires more
input variables, ranging from hydro-geological and weather data to
pesticide physicochemical properties, mobility coefficients, and
degradation rate constants in the aqueous and sediment phases.

	Input parameters used to model the combined residues of pyrimethanil
and its major metabolite, are presented in Table 2.  When possible, EFED
model input guidance was followed
(http://www.epa.gov/oppefed1/models/water/input_guidance2_28_02.htm). 
In cases where data for input parameters for the combined residues were
not available, the most conservative input value was selected.  Data
from supplemental studies conducted with foreign soils which were used
for selecting the mobility parameter are presented in Table 3 (MRID’s
cited in all tables from DP Code D283997).

Table 2: PRZM/EXAM  Input Parameters for Combined Total Residues,
Parent (Pyrimethanil) Plus Major Degradate
(2-Amino-4,6-dimethylpyrimidine)

Parameters	Values & Units 	Sources

Molecular Weight	199.26	Product Chemistry (parent)

Vapor Pressure 25oC	0.000017 torr	Product Chemistry (parent)

Water Solubility @ pH 7.0 and 25oC	121 mg/L	Product Chemistry (parent)

Hydrolysis Half-Life (pH 7)	stable	MRID 456459-15 (parent)

Aerobic Soil Metabolism Half-life 	263 days	Calculated from Combined
Residues 

MRID 456569-18 (half-life times 3 for single value)

Anaerobic Aquatic Metabolism 

(total sediment/water system)	1092 days	MRID 456569-23 (half-life times
3 for single value)

Aerobic Aquatic Metabolism 

(total sediment/water system)	207 days	Calculated from Combined Residues
MRID 456570-01 (90% confidence interval on mean) 

Aqueous Photolysis	stable	MRID 456459-16 (parent)

Soil Water Partition Coefficient	2.85	Average Kd (degradate) MRID
456569-10

Pesticide is Wetted-In	no	Product Label

Crop Management-Florida Strawberries 

   Application Rate	0.8 kg a.i./ha	Product Label

   Number of  Applications	3	Product Label

   Application Interval 	7 days	Product Label

   First Application Date    	October 11	Product Label

   Application Method	Aerial	Product Label

   Spray Efficiency	0.95	EFED

   Spray Drift (Index Res. Scenario)	0.16	EFED



Table 3: Estimation of  Kd and  Koc for the Pyrimethanil Metabolite
(2-amino-4,6-dimethylpyrimidine)

Soil	% Organic Carbon	Kd (mL/g)	Koc (mL/g)	MRID

Loam	3.5	1.9	56	456569-10

Clay Loam	0.9	2.2	240	456569-10

Rilland Loamy Sand	1.32	1.2	94	456569-10

Someren-Heide Sand	3.12	5.2	167	456569-10

Bergeyk Loamy Sand	3.23	3.5	107	456569-10

Haren Sandy Loam	1.58	3.1	197	456569-10

Median Value

2.9	144

	Background Information on SCI-GROW (version 2.3; July 29, 2003)

	SCIGROW is a Tier I, regression-based model that provides a groundwater
screening exposure value to be used in determining the potential risk to
human health from drinking water contaminated with the pesticide.  Since
the SCI-GROW concentrations are likely to be approached in only very
small percentage of drinking water sources (i.e. highly vulnerable
aquifers), it is not appropriate to use SCI- GROW for national or
regional exposure estimates.

	SCIGROW estimates likely groundwater concentrations if the pesticide is
used at the maximum allowable rate in areas where groundwater is
exceptionally vulnerable to contamination.  In most cases, a large
majority of the use area will have groundwater that is less vulnerable
to contamination than the areas used to derive the SCIGROW estimate.

Combined Residues Environmental Fate Input Parameters for SCIGROW :

Parameters	Values & Units 	Sources

Application Rate (3 applications)	0.715 lbs. a.i./acre/season	Product
Label

Organic Carbon Partition Coefficient	56	Lowest Koc (degradate) MRID
456569-10

Aerobic Soil Metabolism Half-life 	87.5 days	Calculated from Combined
Residues 

MRID 456569-18 



SCI-GROW Groundwater Screening Concentration Values:

Residues Modeled	Groundwater Screening Concentrations (ppb)

Combined Residues (pyrimethanil and major metabolite) 	4.8





Appendix I

PRZM/EXAMS Standard Scenario Documentation

FLORIDA STRAWBERRIES

	The field used to represent strawberry production in Florida is located
in Hillsborough or Manatee Counties on the west coast of Central Florida
near Tampa Bay where 95 percent of Florida’s crop is produced.  The
weather station representing the field’s weather is located in Tampa. 
The other major strawberry production area occurs in southeastern
Florida.  According to 2000 production statistics and the 1997 Census of
Agriculture, Florida ranks second behind California in the production of
strawberries; nearly all of Florida’s production is for fresh market. 
Florida produces 100 percent of the domestically produced winter crop. 
Generally, around 6,300 acres are planted each year in Florida. 
Historically, strawberry production occurres primarily on inorganic,
mineral-based soils.  Mineral soils produce higher quality strawberries
than organic muck soils.  Nearly all strawberries are planted by
transplant in Florida.  

	Typical planting occurs on raised beds using full-bed plastic mulch
with 2 to 4 rows of plants per bed; tow to three being most common. 
Plastic mulch is essential for successful maximization of production. 
The crop scenario does not take into account the impact plastic mulch
systems may have on runoff from natural rainfall or sprinkler
irrigation; plastic mulch will not impact runoff in drip irrigation
systems. Ongoing research by the U.S. Department of Agriculture and
pesticide registrants may result in modification to this scenario in the
future. Distance between rows of plants range from 12 to 14 inches for
2-row beds to 10 to 12 inches for 3-row beds.  Distance between plans in
a row runs 8 to 14 inches.  Distance between beds range from 48 to 60
inches between 2-row beds to 60 to 84 inches between 3-row beds. 
Between 15,000 and 25,000 plants are planted per acre in 2-row systems
and 20,000 to 30,000 plants per acre in 3-row systems.  

	Crops are planted between October 7 and November 1 in Central Florida
and from October 1 to December 1 in South Florida.  First crop appears
30 to 60 days following planting under optimal weather conditions.  Up
to four crops per plant each season is possible.  Each subsequent crop
takes approximately 30 days to set; flowers which eventually bear the
next fruit appear continuously from shortly after planting until the end
of harvest.  First harvest occurs from November thru December with final
harvest occurring sometime in late March or early April; depending on
initial planting.  All strawberries in Florida are produced using
irrigation to meet minimum growing requirement by either overhead or
drip irrigation systems.  Generally, water requirements depends on the
soil and the needs of the plants.  Maintaining 100 percent of
evapotranspiration (ET) needs is targeted during the most active growing
season and irrigation will normally be triggered when available soil
moisture is between 66 and 85 percent.  

	The current scenario is set to add irrigation water at 66 percent which
maximizes available runoff water.  The soil selected to simulate the
field is a Myakka sand.  Myakka sand is a sandy, siliceous, hyperthermic
Aeric Alaquods.  These soils, with proper draining, are often used for
truck crops and citrus production and are important soils in strawberry
production.  Myakka sands consists of deep to very deep, poorly to very
poorly drained soils with slow internal drainage. These soils are known
to have high water tables (i.e., 18 inches below surface for 1 to 4
months).  Runoff is slow to ponded, internal permeability is rapid in
the A and E horizon and moderate to moderately rapid in the Bh horizon.
These soils formed in sandy marine deposits and are located on
flatwoods, high tidal areas, flood plains, depressions, and gently
sloping to sloping barrier islands with slopes ranging from 0 to 8
percent.  The soil is of large extent as is classified as a benchmark
soil.  Myakka sand is a Hydrologic Group D soil.

Table 1. PRZM 3.12 Climate and Time Parameters for Hillsborough County,
Florida - Strawberries



Parameter	Value	Source

Starting Date	January 1, 1960	Meteorological File - Tampa, Fl (W12842)

Ending Date	December 31, 1990	Meteorological File - Tampa, Fl (W12842)

Pan Evaporation Factor (PFAC)	0.77

	PRZM Manual Figure 5.1 (EPA, 1998)

Snowmelt Factor (SFAC)	0.0 cm C- 1

	No appreciable snow accumulation occurs in this part of Florida

Minimum Depth of

Evaporation  (ANETD)	25.0 cm

	PRZM Manual Figure 5.2 (EPA, 1998)



Table 2.  PRZM 3.12 Erosion and Landscape Parameters for Hillsborough
County, Florida - Strawberries

Parameter	Value	Source

Method to Calculate Erosion (ERFLAG)	4 (MUSS)	PRZM Manual (EPA, 1998)

USLE K Factor

(USLEK)	0.1 tons EI-1*	GLEAMS Manual; Table of Representative Soils
(USDA, 1990)

USLE LS Factor (USLELS)	0.128	GLEAMS Manual; Table of Representative
Soils (USDA, 1990)

USLE P Factor

(USLEP)	0.5	PRZM Manual (EPA, 1998)

Field Area

(AFIELD)	172 ha	Area of Shipman Reservoir watershed  (EPA, 1999)

NRCS Hyetograph (IREG)	3	PRZM Manual Figure 5.12 (EPA, 1998)

Slope (SLP)	1%	Strawberry fields are laser-leveled

Hydraulic Length (HL)	600 m	Shipman Reservoir (EPA, 1999)

Irrigation Flag (IRFLAG)	2 (cropping period only)	AE 260, Irrigation
Management, Table 2. Irrigation demands during mid-season to final
growth will range 70-85% ET0

Irrigation Type (IRTYP)	3 (Overhead Sprinkler)	AE 260, Irrigation
Management, Table 2. Irrigation demands during mid-season to final
growth will range 70-85% ET0

Leaching Factor (FLEACH)	0.1	Estimated

Fraction of Water Capacity when Irrigation is Applied (PCDEPL)	0.66
http://edis.ifas.ufl.edu/BODY_AE075 

Maximum Rate at which Irrigation is Applied (RATEAP)	1.9 cm hr-1	PRZM
Manual, Table 5.33 (EPA, 1998)

* EI = 100 ft-tons * in/ acre*hr



Table 3.   PRZM 3.12 Crop Parameters for Hillsborough County, Florida -
Strawberries

Parameter	Value	Source

Initial Crop (INICRP)	1	Set to one for all crops (EPA, 2001)

Initial Surface Condition 

(ISCOND)	1	Field are fallow prior to planting

Number of Different Crops

(NDC)	1	Set to crops in simulation - generally one

Number of Cropping Periods

(NCPDS)	30	Set to weather data.  Meteorological File - Tampa, FL
(W12842)

Maximum rainfall Interception storage of crop (CINTCP)	0.1	PIC;
confirmed using Table 5.4 from PRZM Manual (Burns, 1992 and EPA, 1985)

Maximum Active Root Depth (AMXDR)	30cm	http://edis.ifas.ufl.edu

Maximum Canopy Coverage (COVMAX)	40	Cnopy based on estimation from
ground/aerial photography.    HYPERLINK http://edis.ifas.ufl.edu/
http://edis.ifas.ufl.edu/  

Soil Surface Condition After Harvest (ICNAH)	3	Plant residues are left
behind until later in the year when tilled for next series of crops.

Date of Crop Emergence

(EMD, EMM, IYREM)	01/10	First crop. Florida Strawberry Profile, USDA -  
HYPERLINK http://pestdata.ncsu.edu/cropprofiles/docs/Flstrawberries.html
http://pestdata.ncsu.edu/cropprofiles/docs/Flstrawberries.html  or  
HYPERLINK http://edis.ifas.ufl.edu/ http://edis.ifas.ufl.edu/  

Date of Crop Maturity

(MAD, MAM, IYRMAT)	10/11	First crop. Florida Strawberry Profile, USDA - 
 HYPERLINK
http://pestdata.ncsu.edu/cropprofiles/docs/Flstrawberries.html
http://pestdata.ncsu.edu/cropprofiles/docs/Flstrawberries.html  or  
HYPERLINK http://edis.ifas.ufl.edu/ http://edis.ifas.ufl.edu/  

Date of Crop Harvest (HAD, HAM, IYRHAR)	15/02	Last crop. Florida
Strawberry Profile, USDA -   HYPERLINK
http://pestdata.ncsu.edu/cropprofiles/docs/Flstrawberries.html
http://pestdata.ncsu.edu/cropprofiles/docs/Flstrawberries.html  or  
HYPERLINK http://edis.ifas.ufl.edu/ http://edis.ifas.ufl.edu/  

Maximum Dry Weight (WFMAX)	0.0	Set to “0" Not used in simulation

SCS Curve Number (CN)	92, 89, 90	GLEAMS Manual Table A-3; Fallow = SR
Conservation Tillage/poor, Cropping and Residue = Row Crop SR
Conservation tillage/poor; Curve number do not compensate for plastic
mulch.(USDA, 1990)

Manning’s N Value (MNGN)	0.023	RUSLE EPA Pesticide Project:  Uc0STSTN
Strawberry, Tampa, Fl. No-till. Cover Code 5: light cover, residues over
soil surface during critical period

USLE C Factor (USLEC)	0.017 - 0.326	RUSLE EPA Pesticide Project: 
Uc0STSTN Strawberry, Tampa, Fl. No-till. Cover Code 5: light cover,
residues over soil surface during critical period



Table 4.  PRZM 3.12 Myakka Soil Parameters for Hillsborough County,
Florida - Strawberries

Parameter	Value	Verification Source       

Total Soil Depth (CORED)	150 cm	NRCS, National Soils Characterization
Database (NRCS, 2001)



Number of Horizons (NHORIZ)	3

	First, Second, and Third  Soil Horizons (HORIZN = 1,2,3)

Horizon Thickness (THKNS)	15 cm (HORIZN = 1)

75 cm (HORIZN = 2)

60 cm (HORIZN = 3)	NRCS, National Soils Characterization Database (NRCS,
2001)   HYPERLINK http://www.statlab.iastate.edu/soils/ssl/)
http://www.statlab.iastate.edu/soils/ssl/) 

1.25 g ⋅cm-3 (HORIZN = 1)

1.45 g ⋅cm-3 (HORIZN = 2)

1.48 g ⋅cm-3 (HORIZN = 3)

	Initial Water Content (THETO)	0.251 cm3-H2O ⋅cm3-soil (HORIZN = 1)

0.267 cm3-H2O ⋅cm3-soil (HORIZN = 2)

0.133 cm3-H2O ⋅cm3-soil (HORIZN = 3)

	Compartment Thickness (DPN)	0.1 cm (HORIZN = 1)

5 cm (HORIZN =2,3)

	Field Capacity (THEFC)	0.251 cm3-H2O ⋅cm3-soil (HORIZN = 1)

0.267 cm3-H2O ⋅cm3-soil (HORIZN = 2)

0.133 cm3-H2O ⋅cm3-soil (HORIZN = 3)

	Wilting Point (THEWP)	0.101 cm3-H2O ⋅cm3-soil (HORIZN = 1)

0.067 cm3-H2O ⋅cm3-soil (HORIZN = 2)

0.033 cm3-H2O ⋅cm3-soil (HORIZN = 3)

	Organic Carbon Content (OC)	1.16% (HORIZN = 1)

0.116% (HORIZN = 2)

0.058% (HORIZN = 3)

	

Burns. 1992.  Burns, L.A., (Coordinator), B.W. Allen, Jr., M.C. Barber,
S.L. Bird, J.M. Cheplick, M.J. Fendley, D.R. Hartel, C.A. Kittner, F.L.
Mayer, Jr., L.A.  Suarez, and S.E. Wooten.  Pesticide and Industrial
Chemical Risk Analysis and Hazard Assessment, Version 3.0.  (PIRANHA)
Environmental Research Laboratory, Office of Research and Development,
U.S. Environmental Protection Agency, Athens, GA. 1992.

EPA. 1998.   Carsel, R.F., J.C. Imhoff, P.R. Hummel, J.M. Cheplick, and
A.S. Donigian, Jr.  PRZM-3, A Model for Predicting Pesticide and
Nitrogen Fate in the Crop Root and Unsaturated Soil Zones: Users Manual
for Release 3.0.  National Exposure Research Laboratory, Office of
Research and Development, U.S. Environmental Protection Agency, Athens,
GA.

EPA. 1999.  Jones, R.D., J. Breithaupt, J. Carleton, L. Libelo, J. Lin,
R. Matzner, and R. Parker. Guidance for Use of the Index Reservoir in
Drinking Water Exposure Assessments. Environmental Fate and Effects
Division, Office of Pesticide Programs, U.S. Environmental Protection
Agency, Washington. D.C. 

EPA. 2001. Abel, S.A. Procedure for Conducting Quality Assurance and
Quality Control of Existing and New PRZM Field and Orchard Crop Standard
Scenarios. Environmental Fate and Effects Division, Office of Pesticide
Programs, U.S. Environmental Protection Agency, Washington, D.C.

USDA. 1990.  Davis, F.M., R.A. Leonard, W.G. Knisel. GLEAMS User Manual,
Version 1.8.55.  USDA-ARS Southeast Watershed Research Laboratory,
Tifton GA. SEWRL-030190FMD.

USDA. 2000. Revised Universal Soil Loss Equation (RUSLE) EPA Pesticide
Project.  U.S. Department of Agriculture, National Resources
Conservation Service (NRCS) and Agricultural Research Service (ARS).



Appendix II

PRZM/EXAMS Output Data for Combined Residues (Parent Plus Metabolite)

stored as TLstraw.out

Chemical: pyrimethanil

PRZM environment: FLstrawberryC.txt	modified Friday, 4 July 2003 at
20:12:58

EXAMS environment: ir298.exv	modified Thuday, 29 August 2002 at 15:34:12

Metfile: w12842.dvf	modified Wedday, 3 July 2002 at 09:04:28

Water segment concentrations (ppb)

Year	Peak	96 hr	21 Day	60 Day	90 Day	Yearly

1961	67.29	63.75	57.04	44	33.33	8.219

1962	65.9	62.54	52.5	39.19	29.95	9.188

1963	64.95	61.46	55.87	42.75	33.28	9.715

1964	67.54	63.86	57.47	41.44	31.65	9.504

1965	79.64	75.58	66.21	49.03	38.1	11.04

1966	60.62	57.55	51.4	38.14	28.65	9.06

1967	65.49	61.99	54.31	39.66	30.36	9.222

1968	93.56	88.64	83.54	63.81	47.53	13.36

1969	39.69	37.74	35.24	28.82	22.19	8.088

1970	55.24	52.34	46.34	34.01	26.69	7.842

1971	59.98	56.93	54.47	41.82	31.63	9.279

1972	78.4	74.34	65.56	47.01	35.69	10.44

1973	71.56	68.23	61.83	45.8	35.05	10.56

1974	68.29	64.7	59.18	44.34	34.38	10.32

1975	101	96.05	83.86	62.15	47.36	13.51

1976	48.31	46.09	42.78	34.13	26.43	9.08

1977	63	59.9	51.77	38.98	29.74	8.864

1978	72.69	70.1	62.5	45.84	34.19	10.27

1979	74.45	70.67	60.97	44.72	33.91	10.28

1980	55.94	53.22	49.34	38.07	29.53	9.198

1981	65.23	62.12	57.65	44.58	34.24	10.3

1982	60.48	57.34	51.43	39	29.68	9.377

1983	58.26	55.38	47.35	35.87	26.83	8.262

1984	50.21	47.79	43.47	33.62	25.85	7.949

1985	88.3	84.29	69.82	51.42	39.5	11.23

1986	100	96.58	80.79	56.04	42.02	12.67

1987	104	98.29	91.56	66.52	50.71	14.88

1988	63.51	60.31	53.51	39.56	30.78	10.31

1989	56.04	53.26	47.73	36.35	27.57	8.521

1990	13.57	12.87	10.83	7.996	6.13	3.078

Sorted results

Prob.	Peak	96 hr	21 Day	60 Day	90 Day	Yearly

0.032258064516129	104	98.29	91.56	66.52	50.71	14.88

0.0645161290322581	101	96.58	83.86	63.81	47.53	13.51

0.0967741935483871	100	96.05	83.54	62.15	47.36	13.36

0.129032258064516	93.56	88.64	80.79	56.04	42.02	12.67

0.161290322580645	88.3	84.29	69.82	51.42	39.5	11.23

0.193548387096774	79.64	75.58	66.21	49.03	38.1	11.04

0.225806451612903	78.4	74.34	65.56	47.01	35.69	10.56

0.258064516129032	74.45	70.67	62.5	45.84	35.05	10.44

0.290322580645161	72.69	70.1	61.83	45.8	34.38	10.32

0.32258064516129	71.56	68.23	60.97	44.72	34.24	10.31

0.354838709677419	68.29	64.7	59.18	44.58	34.19	10.3

0.387096774193548	67.54	63.86	57.65	44.34	33.91	10.28

0.419354838709677	67.29	63.75	57.47	44	33.33	10.27

0.451612903225806	65.9	62.54	57.04	42.75	33.28	9.715

0.483870967741936	65.49	62.12	55.87	41.82	31.65	9.504

0.516129032258065	65.23	61.99	54.47	41.44	31.63	9.377

0.548387096774194	64.95	61.46	54.31	39.66	30.78	9.279

0.580645161290323	63.51	60.31	53.51	39.56	30.36	9.222

0.612903225806452	63	59.9	52.5	39.19	29.95	9.198

0.645161290322581	60.62	57.55	51.77	39	29.74	9.188

0.67741935483871	60.48	57.34	51.43	38.98	29.68	9.08

0.709677419354839	59.98	56.93	51.4	38.14	29.53	9.06

0.741935483870968	58.26	55.38	49.34	38.07	28.65	8.864

0.774193548387097	56.04	53.26	47.73	36.35	27.57	8.521

0.806451612903226	55.94	53.22	47.35	35.87	26.83	8.262

0.838709677419355	55.24	52.34	46.34	34.13	26.69	8.219

0.870967741935484	50.21	47.79	43.47	34.01	26.43	8.088

0.903225806451613	48.31	46.09	42.78	33.62	25.85	7.949

0.935483870967742	39.69	37.74	35.24	28.82	22.19	7.842

0.967741935483871	13.57	12.87	10.83	7.996	6.13	3.078

0.1	99.356	95.309	83.265	61.539	46.826	13.291

					Average of yearly averages:	9.7872

Inputs generaged by pe4.pl - 14-May-2003

Values not adjusted for Regional Percent Cropped Area factor of 38%.

stored as TLgrape.out

Chemical: pyrimethanil

PRZM environment: CAgrapesC.txt	modified Satday, 12 October 2002 at
16:36:14

EXAMS environment: ir298.exv	modified Thuday, 29 August 2002 at 15:34:12

Metfile: w93193.dvf	modified Wedday, 3 July 2002 at 09:04:24

Water segment concentrations (ppb)

Year	Peak	96 hr	21 Day	60 Day	90 Day	Yearly

1961	9.109	8.988	8.5	7.506	6.816	3.168

1962	10.17	10.05	9.558	8.467	7.679	3.77

1963	10.2	10.06	9.565	8.477	7.696	3.755

1964	10.21	10.07	9.528	8.391	7.607	3.655

1965	13.86	13.68	12.96	11.39	10.3	4.898

1966	10.59	10.45	9.882	8.691	7.904	3.915

1967	10.38	10.27	9.879	8.779	7.978	3.94

1968	10.31	10.17	9.638	8.506	7.713	3.748

1969	10.16	10.08	9.593	8.451	7.632	3.716

1970	14.45	14.26	13.5	11.89	10.88	5.211

1971	10.51	10.36	9.752	8.511	7.714	3.735

1972	10.05	9.918	9.368	8.198	7.414	3.555

1973	10.07	9.937	9.538	8.491	7.696	3.786

1974	10.29	10.15	9.573	8.403	7.615	3.706

1975	10.18	10.05	9.531	8.487	7.746	3.936

1976	10.45	10.31	9.771	8.684	7.921	3.93

1977	10.26	10.12	9.552	8.337	7.532	3.599

1978	12.39	12.22	11.55	10.17	9.243	4.333

1979	10.3	10.16	9.605	8.361	7.534	3.573

1980	11.17	11.01	10.37	9.052	8.149	3.791

1981	10.15	10.01	9.521	8.366	7.537	3.481

1982	10.17	10.06	9.736	8.669	7.857	3.736

1983	12.51	12.34	11.72	10.33	9.444	4.421

1984	10.29	10.15	9.598	8.392	7.556	3.534

1985	10.11	9.99	9.496	8.392	7.593	3.639

1986	12.34	12.18	11.72	10.45	9.463	4.576

1987	11.09	10.95	10.39	9.152	8.301	4.11

1988	10.33	10.2	9.665	8.56	7.796	3.859

1989	11.45	11.29	10.64	9.273	8.394	3.971

1990	10.27	10.15	9.657	8.534	7.735	3.737

Sorted results

Prob.	Peak	96 hr	21 Day	60 Day	90 Day	Yearly

0.032258064516129	14.45	14.26	13.5	11.89	10.88	5.211

0.0645161290322581	13.86	13.68	12.96	11.39	10.3	4.898

0.0967741935483871	12.51	12.34	11.72	10.45	9.463	4.576

0.129032258064516	12.39	12.22	11.72	10.33	9.444	4.421

0.161290322580645	12.34	12.18	11.55	10.17	9.243	4.333

0.193548387096774	11.45	11.29	10.64	9.273	8.394	4.11

0.225806451612903	11.17	11.01	10.39	9.152	8.301	3.971

0.258064516129032	11.09	10.95	10.37	9.052	8.149	3.94

0.290322580645161	10.59	10.45	9.882	8.779	7.978	3.936

0.32258064516129	10.51	10.36	9.879	8.691	7.921	3.93

0.354838709677419	10.45	10.31	9.771	8.684	7.904	3.915

0.387096774193548	10.38	10.27	9.752	8.669	7.857	3.859

0.419354838709677	10.33	10.2	9.736	8.56	7.796	3.791

0.451612903225806	10.31	10.17	9.665	8.534	7.746	3.786

0.483870967741936	10.3	10.16	9.657	8.511	7.735	3.77

0.516129032258065	10.29	10.15	9.638	8.506	7.714	3.755

0.548387096774194	10.29	10.15	9.605	8.491	7.713	3.748

0.580645161290323	10.27	10.15	9.598	8.487	7.696	3.737

0.612903225806452	10.26	10.12	9.593	8.477	7.696	3.736

0.645161290322581	10.21	10.08	9.573	8.467	7.679	3.735

0.67741935483871	10.2	10.07	9.565	8.451	7.632	3.716

0.709677419354839	10.18	10.06	9.558	8.403	7.615	3.706

0.741935483870968	10.17	10.06	9.552	8.392	7.607	3.655

0.774193548387097	10.17	10.05	9.538	8.392	7.593	3.639

0.806451612903226	10.16	10.05	9.531	8.391	7.556	3.599

0.838709677419355	10.15	10.01	9.528	8.366	7.537	3.573

0.870967741935484	10.11	9.99	9.521	8.361	7.534	3.555

0.903225806451613	10.07	9.937	9.496	8.337	7.532	3.534

0.935483870967742	10.05	9.918	9.368	8.198	7.414	3.481

0.967741935483871	9.109	8.988	8.5	7.506	6.816	3.168

0.1	12.498	12.328	11.72	10.438	9.4611	4.5605

					Average of yearly averages:	3.8928

Inputs generaged by pe4.pl - 14-May-2003

Values not adjusted for Regional Percent Cropped Area factor of 56%.

stored as TLnuts.out

Chemical: pyrimethanil

PRZM environment: ORfilbertsC.txt	modified Satday, 12 October 2002 at
17:18:04

EXAMS environment: ir298.exv	modified Thuday, 29 August 2002 at 15:34:12

Metfile: w24232.dvf	modified Wedday, 3 July 2002 at 09:06:10

Water segment concentrations (ppb)

Year	Peak	96 hr	21 Day	60 Day	90 Day	Yearly

1961	18.34	17.96	17.19	15.15	13.66	5.945

1962	25.76	25.23	23.33	19.65	17.4	7.565

1963	23.75	23.27	21.58	18.09	15.98	7.171

1964	8.597	8.416	7.73	6.605	5.894	2.794

1965	5.911	5.808	5.396	4.961	4.681	2.259

1966	30.08	29.45	28.04	23.79	20.98	8.666

1967	6.591	6.454	5.917	5.043	4.511	2.202

1968	6.266	6.165	5.735	4.921	4.467	2.025

1969	5.43	5.324	4.904	4.186	3.747	1.845

1970	6.159	6.043	5.584	4.725	4.208	1.875

1971	16.87	16.5	15.47	14.55	13.26	5.882

1972	11.99	11.78	11.07	10.02	9.181	4.259

1973	7.076	6.943	6.565	5.732	5.171	2.409

1974	19.07	18.68	17.45	14.77	13.44	5.946

1975	17.56	17.2	15.87	13.38	11.88	5.34

1976	12.03	11.79	11.06	9.483	8.466	4.034

1977	7.775	7.619	7.01	6.13	5.569	2.646

1978	5.615	5.521	5.144	4.549	4.336	2.147

1979	7.499	7.369	6.85	6.016	5.562	2.578

1980	11.33	11.14	10.57	9.754	9.084	4.215

1981	10.35	10.15	9.838	9.343	8.644	4.057

1982	7.253	7.15	6.782	6.479	6.026	2.884

1983	17.42	17.12	16.08	13.91	12.82	5.815

1984	7.098	7.005	6.51	5.898	5.364	2.605

1985	10.02	9.855	9.114	7.813	7.041	3.277

1986	8.775	8.597	7.883	6.852	6.257	2.855

1987	7.051	6.916	6.384	5.817	5.356	2.524

1988	8.022	7.858	7.558	6.712	6.095	2.755

1989	14.71	14.41	13.26	11.37	10.17	4.316

1990	8.795	8.631	7.984	7.017	6.329	2.851

Sorted results

Prob.	Peak	96 hr	21 Day	60 Day	90 Day	Yearly

0.032258064516129	30.08	29.45	28.04	23.79	20.98	8.666

0.0645161290322581	25.76	25.23	23.33	19.65	17.4	7.565

0.0967741935483871	23.75	23.27	21.58	18.09	15.98	7.171

0.129032258064516	19.07	18.68	17.45	15.15	13.66	5.946

0.161290322580645	18.34	17.96	17.19	14.77	13.44	5.945

0.193548387096774	17.56	17.2	16.08	14.55	13.26	5.882

0.225806451612903	17.42	17.12	15.87	13.91	12.82	5.815

0.258064516129032	16.87	16.5	15.47	13.38	11.88	5.34

0.290322580645161	14.71	14.41	13.26	11.37	10.17	4.316

0.32258064516129	12.03	11.79	11.07	10.02	9.181	4.259

0.354838709677419	11.99	11.78	11.06	9.754	9.084	4.215

0.387096774193548	11.33	11.14	10.57	9.483	8.644	4.057

0.419354838709677	10.35	10.15	9.838	9.343	8.466	4.034

0.451612903225806	10.02	9.855	9.114	7.813	7.041	3.277

0.483870967741936	8.795	8.631	7.984	7.017	6.329	2.884

0.516129032258065	8.775	8.597	7.883	6.852	6.257	2.855

0.548387096774194	8.597	8.416	7.73	6.712	6.095	2.851

0.580645161290323	8.022	7.858	7.558	6.605	6.026	2.794

0.612903225806452	7.775	7.619	7.01	6.479	5.894	2.755

0.645161290322581	7.499	7.369	6.85	6.13	5.569	2.646

0.67741935483871	7.253	7.15	6.782	6.016	5.562	2.605

0.709677419354839	7.098	7.005	6.565	5.898	5.364	2.578

0.741935483870968	7.076	6.943	6.51	5.817	5.356	2.524

0.774193548387097	7.051	6.916	6.384	5.732	5.171	2.409

0.806451612903226	6.591	6.454	5.917	5.043	4.681	2.259

0.838709677419355	6.266	6.165	5.735	4.961	4.511	2.202

0.870967741935484	6.159	6.043	5.584	4.921	4.467	2.147

0.903225806451613	5.911	5.808	5.396	4.725	4.336	2.025

0.935483870967742	5.615	5.521	5.144	4.549	4.208	1.875

0.967741935483871	5.43	5.324	4.904	4.186	3.747	1.845

0.1	23.282	22.811	21.167	17.796	15.748	7.0485

					Average of yearly averages:	3.85806666666667

Inputs generaged by pe4.pl - 14-May-2003

Values not adjusted for Regional Percent Cropped Area factor of 36%.

stored as TLonion.out

Chemical: pyrimethanil

PRZM environment: GAOnionsC.txt	modified Thuday, 30 January 2003 at
08:26:54

EXAMS environment: ir298.exv	modified Thuday, 29 August 2002 at 15:34:12

Metfile: w03822.dvf	modified Wedday, 3 July 2002 at 09:04:32

Water segment concentrations (ppb)

Year	Peak	96 hr	21 Day	60 Day	90 Day	Yearly

1961	38.21	36.72	32.58	26.57	21.71	6.866

1962	49.76	47.7	40.79	33.53	27.8	8.555

1963	40.3	38.58	33.23	24.13	19.69	6.466

1964	18.6	17.8	15.69	14.6	13.45	4.447

1965	31.54	30.23	28.53	23.71	20.04	6.288

1966	49.83	47.82	43.81	36.16	30.98	9.764

1967	44.11	42.31	38.19	31.48	25.67	8.051

1968	27.5	26.38	23.55	19.43	16.73	5.604

1969	42.78	40.97	35.55	26.83	22.75	7.257

1970	59.04	56.54	50.88	39.51	32.51	9.955

1971	18.48	17.71	15.54	13.72	12.02	4.009

1972	74.6	71.45	60.27	43.72	35.07	10.54

1973	37.81	36.23	33.19	29.12	24.06	7.469

1974	21.72	20.8	18.81	16.58	14.63	4.8

1975	37.54	36.02	31.03	27.46	23.51	7.654

1976	32.05	30.78	27.41	25.01	21.16	6.861

1977	22.38	21.48	19.21	14.82	13.73	4.835

1978	35.99	34.53	33.06	25.86	22.38	7.287

1979	23.93	22.96	19.95	16.97	14.73	4.96

1980	61.86	59.5	54.31	43.07	35.26	10.91

1981	29.34	28.13	26.25	22.29	19.23	6.125

1982	22.34	21.6	18.74	15.47	13.76	4.949

1983	103	98.58	83.38	59.86	49.35	15.26

1984	49.78	47.79	44.54	34.78	29.1	9.149

1985	33.56	32.44	29.32	24.85	20.49	6.499

1986	47.55	45.64	40.34	34.46	28.61	8.877

1987	27.77	26.98	24.13	19.04	16.3	5.29

1988	34.05	32.63	28.28	22.2	19.3	6.349

1989	41.49	40.63	35.13	26.26	21.27	6.698

1990	40.59	38.94	35.46	29.06	23.89	7.376

Sorted results

Prob.	Peak	96 hr	21 Day	60 Day	90 Day	Yearly

0.032258064516129	103	98.58	83.38	59.86	49.35	15.26

0.0645161290322581	74.6	71.45	60.27	43.72	35.26	10.91

0.0967741935483871	61.86	59.5	54.31	43.07	35.07	10.54

0.129032258064516	59.04	56.54	50.88	39.51	32.51	9.955

0.161290322580645	49.83	47.82	44.54	36.16	30.98	9.764

0.193548387096774	49.78	47.79	43.81	34.78	29.1	9.149

0.225806451612903	49.76	47.7	40.79	34.46	28.61	8.877

0.258064516129032	47.55	45.64	40.34	33.53	27.8	8.555

0.290322580645161	44.11	42.31	38.19	31.48	25.67	8.051

0.32258064516129	42.78	40.97	35.55	29.12	24.06	7.654

0.354838709677419	41.49	40.63	35.46	29.06	23.89	7.469

0.387096774193548	40.59	38.94	35.13	27.46	23.51	7.376

0.419354838709677	40.3	38.58	33.23	26.83	22.75	7.287

0.451612903225806	38.21	36.72	33.19	26.57	22.38	7.257

0.483870967741936	37.81	36.23	33.06	26.26	21.71	6.866

0.516129032258065	37.54	36.02	32.58	25.86	21.27	6.861

0.548387096774194	35.99	34.53	31.03	25.01	21.16	6.698

0.580645161290323	34.05	32.63	29.32	24.85	20.49	6.499

0.612903225806452	33.56	32.44	28.53	24.13	20.04	6.466

0.645161290322581	32.05	30.78	28.28	23.71	19.69	6.349

0.67741935483871	31.54	30.23	27.41	22.29	19.3	6.288

0.709677419354839	29.34	28.13	26.25	22.2	19.23	6.125

0.741935483870968	27.77	26.98	24.13	19.43	16.73	5.604

0.774193548387097	27.5	26.38	23.55	19.04	16.3	5.29

0.806451612903226	23.93	22.96	19.95	16.97	14.73	4.96

0.838709677419355	22.38	21.6	19.21	16.58	14.63	4.949

0.870967741935484	22.34	21.48	18.81	15.47	13.76	4.835

0.903225806451613	21.72	20.8	18.74	14.82	13.73	4.8

0.935483870967742	18.6	17.8	15.69	14.6	13.45	4.447

0.967741935483871	18.48	17.71	15.54	13.72	12.02	4.009

0.1	61.578	59.204	53.967	42.714	34.814	10.4815

					Average of yearly averages:	7.305

Inputs generaged by pe4.pl - 14-May-2003

Values not adjusted for Regional Percent Cropped Area factor of 38%.

stored as TLplums.out

Chemical: pyrimethanil

PRZM environment: CAfruitC.txt	modified Satday, 12 October 2002 at
16:35:16

EXAMS environment: ir298.exv	modified Thuday, 29 August 2002 at 15:34:12

Metfile: w93193.dvf	modified Wedday, 3 July 2002 at 09:04:24

Water segment concentrations (ppb)

Year	Peak	96 hr	21 Day	60 Day	90 Day	Yearly

1961	5.257	5.187	4.905	4.322	3.968	1.853

1962	5.879	5.809	5.521	4.879	4.472	2.208

1963	7.763	7.656	7.414	6.68	6.067	2.944

1964	6.121	6.041	5.715	5.051	4.621	2.283

1965	14.29	14.11	13.36	11.8	10.6	4.888

1966	6.712	6.624	6.269	5.557	5.093	2.659

1967	7.132	7.037	6.665	5.941	5.436	2.69

1968	6.09	6.01	5.685	5.03	4.6	2.274

1969	6.231	6.155	5.847	5.153	4.695	2.295

1970	11.26	11.11	10.51	9.469	8.716	4.154

1971	6.343	6.253	5.889	5.181	4.724	2.363

1972	5.826	5.747	5.427	4.759	4.342	2.104

1973	7.012	6.92	6.539	5.806	5.286	2.611

1974	6.195	6.109	5.802	5.15	4.711	2.335

1975	5.921	5.845	5.542	4.936	4.556	2.336

1976	6.032	5.954	5.641	5.021	4.628	2.31

1977	5.989	5.917	5.611	4.905	4.464	2.15

1978	8.762	8.644	8.231	7.465	6.842	3.209

1979	6.114	6.033	5.702	4.982	4.512	2.197

1980	6.659	6.563	6.179	5.448	4.939	2.311

1981	7.429	7.329	6.915	6.066	5.47	2.536

1982	7.652	7.59	7.34	6.66	6.054	2.904

1983	9.735	9.601	9.273	8.382	7.7	3.667

1984	6.206	6.124	5.79	5.085	4.601	2.229

1985	5.875	5.804	5.515	4.863	4.443	2.148

1986	12.86	12.69	12	10.49	9.45	4.47

1987	6.952	6.865	6.604	5.886	5.406	2.808

1988	6.055	5.978	5.667	5.025	4.627	2.321

1989	7.832	7.721	7.493	6.695	6.092	2.895

1990	6.102	6.029	5.733	5.063	4.632	2.284

Sorted results

Prob.	Peak	96 hr	21 Day	60 Day	90 Day	Yearly

0.032258064516129	14.29	14.11	13.36	11.8	10.6	4.888

0.0645161290322581	12.86	12.69	12	10.49	9.45	4.47

0.0967741935483871	11.26	11.11	10.51	9.469	8.716	4.154

0.129032258064516	9.735	9.601	9.273	8.382	7.7	3.667

0.161290322580645	8.762	8.644	8.231	7.465	6.842	3.209

0.193548387096774	7.832	7.721	7.493	6.695	6.092	2.944

0.225806451612903	7.763	7.656	7.414	6.68	6.067	2.904

0.258064516129032	7.652	7.59	7.34	6.66	6.054	2.895

0.290322580645161	7.429	7.329	6.915	6.066	5.47	2.808

0.32258064516129	7.132	7.037	6.665	5.941	5.436	2.69

0.354838709677419	7.012	6.92	6.604	5.886	5.406	2.659

0.387096774193548	6.952	6.865	6.539	5.806	5.286	2.611

0.419354838709677	6.712	6.624	6.269	5.557	5.093	2.536

0.451612903225806	6.659	6.563	6.179	5.448	4.939	2.363

0.483870967741936	6.343	6.253	5.889	5.181	4.724	2.336

0.516129032258065	6.231	6.155	5.847	5.153	4.711	2.335

0.548387096774194	6.206	6.124	5.802	5.15	4.695	2.321

0.580645161290323	6.195	6.109	5.79	5.085	4.632	2.311

0.612903225806452	6.121	6.041	5.733	5.063	4.628	2.31

0.645161290322581	6.114	6.033	5.715	5.051	4.627	2.295

0.67741935483871	6.102	6.029	5.702	5.03	4.621	2.284

0.709677419354839	6.09	6.01	5.685	5.025	4.601	2.283

0.741935483870968	6.055	5.978	5.667	5.021	4.6	2.274

0.774193548387097	6.032	5.954	5.641	4.982	4.556	2.229

0.806451612903226	5.989	5.917	5.611	4.936	4.512	2.208

0.838709677419355	5.921	5.845	5.542	4.905	4.472	2.197

0.870967741935484	5.879	5.809	5.521	4.879	4.464	2.15

0.903225806451613	5.875	5.804	5.515	4.863	4.443	2.148

0.935483870967742	5.826	5.747	5.427	4.759	4.342	2.104

0.967741935483871	5.257	5.187	4.905	4.322	3.968	1.853

0.1	11.1075	10.9591	10.3863	9.3603	8.6144	4.1053

					Average of yearly averages:	2.6812

Inputs generaged by pe4.pl - 14-May-2003

Values not adjusted for Regional Percent Cropped Area factor of 56%.

Appendix III

PRZM/EXAMS Input Data for Combined Residues (Parent Plus Metabolite)

Metfile:	w12842.dvf

PRZM scenario:	FLstrawberryC.txt

EXAMS environment file:	ir298.exv

Chemical Name:	pyrimethanil

Description	Variable Name	Value	Units	Comments

Molecular weight	mwt	199.26	g/mol

Henry's Law Const.	henry	.000002	atm-m^3/mol

Vapor Pressure	vapr	.000017	torr

Solubility	sol	121	mg/L

Kd	Kd	2.85	mg/L

Koc	Koc		mg/L

Photolysis half-life	kdp	0	days	Half-life

Aerobic Aquatic Metabolism	kbacw	206.7	days	Halfife

Anaerobic Aquatic Metabolism	kbacs	1092	days	Halfife

Aerobic Soil Metabolism	asm	262.4	days	Halfife

Hydrolysis:	pH 7	0	days	Half-life

Method:	CAM	1	integer	See PRZM manual

Incorporation Depth:	DEPI	0	cm

Application Rate:	TAPP	0.8	kg/ha

Application Efficiency:	APPEFF	0.95	fraction

Spray Drift	DRFT	0.16	fraction of application rate applied to pond

Application Date	Date	11-10	dd/mm or dd/mmm or dd-mm or dd-mmm

Interval 1	interval	7	days	Set to 0 or delete line for single app.

Interval 2	interval	7	days	Set to 0 or delete line for single app.

Record 17:	FILTRA	

	IPSCND	1

	UPTKF	

Record 18:	PLVKRT	

	PLDKRT	

	FEXTRC	0.5

Flag for Index Res. Run	IR	IR

Flag for runoff calc.	RUNOFF	total	none, monthly or total(average of
entire run)

set mode = 3

set outfil(4) to Y

set outfil(2) to N

READ ENV C:\models\INPUTS\EXAMSenv\ir298.exv

READ MET C:\models\INPUTS\Metfiles\w12842.dvf

SET YEAR1 = 1961

recall chem 1

chemical name is pyrimethanil

set KPS(1,1) to 2.85

set MWT(1) = 199.26

set HENRY(1) = .000002

set VAPR(1) = .000017

set SOL(1,1) = 121

set KBACW(*,1,1) = 0.00013972487916464

set KBACS(*,1,1) = 2.6447923556164e-005

set QTBAS(*,1,1) = 2

set QTBAW(*,1,1) = 2

READ PRZM P2E-C1.D61

SET STFLO(1,*) = 0

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

RUN

READ PRZM P2E-C1.D62

SET STFLO(1,*) = 0

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

CONTINUE

READ PRZM P2E-C1.D63

SET STFLO(1,*) = 0

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

CONTINUE

READ PRZM P2E-C1.D64

SET STFLO(1,*) = 0

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

CONTINUE

Metfile:	w93193.dvf

PRZM scenario:	CAgrapesC.txt

EXAMS environment file:	ir298.exv

Chemical Name:	pyrimethanil

Description	Variable Name	Value	Units	Comments

Molecular weight	mwt	199.26	g/mol

Henry's Law Const.	henry	.000002	atm-m^3/mol

Vapor Pressure	vapr	.000017	torr			

Solubility	sol	121	mg/L

Kd	Kd	2.85	mg/L

Koc	Koc		mg/L

Photolysis half-life	kdp	0	days	Half-life

Aerobic Aquatic Metabolism	kbacw	206.7	days	Halfife

Anaerobic Aquatic Metabolism	kbacs	1092	days	Halfife

Aerobic Soil Metabolism	asm	262.4	days	Halfife

Hydrolysis:	pH 7	0	days	Half-life

Method:	CAM	1	integer	See PRZM manual

Incorporation Depth:	DEPI	0	cm

Application Rate:	TAPP	0.8	kg/ha

Application Efficiency:	APPEFF	0.95	fraction

Spray Drift	DRFT	0.16	fraction of application rate applied to pond

Application Date	Date	01-03	dd/mm or dd/mmm or dd-mm or dd-mmm

Interval 1	interval	7	days	Set to 0 or delete line for single app.

Record 17:	FILTRA	

	IPSCND	1

	UPTKF	

Record 18:	PLVKRT	

	PLDKRT	

	FEXTRC	0.5

Flag for Index Res. Run	IR	IR

Flag for runoff calc.	RUNOFF	total	none, monthly or total(average of
entire run)

set mode = 3

set outfil(4) to Y

set outfil(2) to N

READ ENV C:\models\INPUTS\EXAMSenv\ir298.exv

READ MET C:\models\INPUTS\Metfiles\w93193.dvf

SET YEAR1 = 1961

recall chem 1

chemical name is pyrimethanil

set KPS(1,1) to 2.85

set MWT(1) = 199.26

set HENRY(1) = .000002

set VAPR(1) = .000017

set SOL(1,1) = 121

set KBACW(*,1,1) = 0.00013972487916464

set KBACS(*,1,1) = 2.6447923556164e-005

set QTBAS(*,1,1) = 2

set QTBAW(*,1,1) = 2

READ PRZM P2E-C1.D61

SET STFLO(1,*) = 2.64291320616957

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

RUN

READ PRZM P2E-C1.D62

SET STFLO(1,*) = 2.64291320616957

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

CONTINUE

READ PRZM P2E-C1.D63

SET STFLO(1,*) = 2.64291320616957

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

CONTINUE

Metfile:	w24232.dvf

PRZM scenario:	ORfilbertsC.txt

EXAMS environment file:	ir298.exv

Chemical Name:	pyrimethanil

Description	Variable Name	Value	Units	Comments

Molecular weight	mwt	199.26	g/mol

Henry's Law Const.	henry	.000002	atm-m^3/mol

Vapor Pressure	vapr	.000017	torr

Solubility	sol	121	mg/L

Kd	Kd	2.85	mg/L

Koc	Koc		mg/L

Photolysis half-life	kdp	0	days	Half-life

Aerobic Aquatic Metabolism	kbacw	206.7	days	Halfife

Anaerobic Aquatic Metabolism	kbacs	1092	days	Halfife

Aerobic Soil Metabolism	asm	262.4	days	Halfife

Hydrolysis:	pH 7	0	days	Half-life

Method:	CAM	1	integer	See PRZM manual

Incorporation Depth:	DEPI	0	cm

Application Rate:	TAPP	0.8	kg/ha

Application Efficiency:	APPEFF	0.99	fraction

Spray Drift	DRFT	0.063	fraction of application rate applied to pond

Application Date	Date	01-03	dd/mm or dd/mmm or dd-mm or dd-mmm

Interval 1	interval	7	days	Set to 0 or delete line for single app.

Interval 2	interval	7	days	Set to 0 or delete line for single app.

Record 17:	FILTRA	

	IPSCND	1

	UPTKF	

Record 18:	PLVKRT	

	PLDKRT	

	FEXTRC	0.5

Flag for Index Res. Run	IR	IR

Flag for runoff calc.	RUNOFF	total	none, monthly or total(average of
entire run)

set mode = 3

set outfil(4) to Y

set outfil(2) to N

READ ENV C:\models\INPUTS\EXAMSenv\ir298.exv

READ MET C:\models\INPUTS\Metfiles\w24232.dvf

SET YEAR1 = 1961

recall chem 1

chemical name is pyrimethanil

set KPS(1,1) to 2.85

set MWT(1) = 199.26

set HENRY(1) = .000002

set VAPR(1) = .000017

set SOL(1,1) = 121

set KBACW(*,1,1) = 0.00013972487916464

set KBACS(*,1,1) = 2.6447923556164e-005

set QTBAS(*,1,1) = 2

set QTBAW(*,1,1) = 2

READ PRZM P2E-C1.D61

SET STFLO(1,*) = 20.1536917039336

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

RUN

READ PRZM P2E-C1.D62

SET STFLO(1,*) = 20.1536917039336

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

CONTINUE

READ PRZM P2E-C1.D63

SET STFLO(1,*) = 20.1536917039336

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

CONTINUE

READ PRZM P2E-C1.D64

SET STFLO(1,*) = 20.1536917039336

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

CONTINUE

Metfile:	w03822.dvf

PRZM scenario:	GAOnionsC.txt

EXAMS environment file:	ir298.exv

Chemical Name:	pyrimethanil

Description	Variable Name	Value	Units	Comments

Molecular weight	mwt	199.26	g/mol

Henry's Law Const.	henry	.000002	atm-m^3/mol

Vapor Pressure	vapr	.000017	torr

Solubility	sol	121	mg/L

Kd	Kd	2.85	mg/L

Koc	Koc		mg/L

Photolysis half-life	kdp	0	days	Half-life

Aerobic Aquatic Metabolism	kbacw	206.7	days	Halfife

Anaerobic Aquatic Metabolism	kbacs	1092	days	Halfife

Aerobic Soil Metabolism	asm	262.4	days	Halfife

Hydrolysis:	pH 7	0	days	Half-life

Method:	CAM	1	integer	See PRZM manual

Incorporation Depth:	DEPI	0	cm

Application Rate:	TAPP	0.8	kg/ha

Application Efficiency:	APPEFF	0.95	fraction

Spray Drift	DRFT	0.16	fraction of application rate applied to pond

Application Date	Date	01-03	dd/mm or dd/mmm or dd-mm or dd-mmm

Interval 1	interval	7	days	Set to 0 or delete line for single app.

Interval 2	interval	7	days	Set to 0 or delete line for single app.

Record 17:	FILTRA	

	IPSCND	1

	UPTKF	

Record 18:	PLVKRT	

	PLDKRT	

	FEXTRC	0.5

Flag for Index Res. Run	IR	IR

Flag for runoff calc.	RUNOFF	total	none, monthly or total(average of
entire run)

set mode = 3

set outfil(4) to Y

set outfil(2) to N

READ ENV C:\models\INPUTS\EXAMSenv\ir298.exv

READ MET C:\models\INPUTS\Metfiles\w03822.dvf

SET YEAR1 = 1961

recall chem 1

chemical name is pyrimethanil

set KPS(1,1) to 2.85

set MWT(1) = 199.26

set HENRY(1) = .000002

set VAPR(1) = .000017

set SOL(1,1) = 121

set KBACW(*,1,1) = 0.00013972487916464

set KBACS(*,1,1) = 2.6447923556164e-005

set QTBAS(*,1,1) = 2

set QTBAW(*,1,1) = 2

READ PRZM P2E-C1.D61

SET STFLO(1,*) = 80.7593319339235

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

RUN

READ PRZM P2E-C1.D62

SET STFLO(1,*) = 80.7593319339235

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

CONTINUE

READ PRZM P2E-C1.D63

SET STFLO(1,*) = 80.7593319339235

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

CONTINUE

READ PRZM P2E-C1.D64

SET STFLO(1,*) = 80.7593319339235

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

CONTINUE

Metfile:	w93193.dvf

PRZM scenario:	CAfruitC.txt

EXAMS environment file:	ir298.exv

Chemical Name:	pyrimethanil

Description	Variable Name	Value	Units	Comments

Molecular weight	mwt	199.26	g/mol

Henry's Law Const.	henry	.000002	atm-m^3/mol

Vapor Pressure	vapr	.000017	torr

Solubility	sol	121	mg/L

Kd	Kd	2.85	mg/L

Koc	Koc		mg/L

Photolysis half-life	kdp	0	days	Half-life

Aerobic Aquatic Metabolism	kbacw	206.7	days	Halfife

Anaerobic Aquatic Metabolism	kbacs	1092	days	Halfife

Aerobic Soil Metabolism	asm	262.4	days	Halfife

Hydrolysis:	pH 7	0	days	Half-life

Method:	CAM	1	integer	See PRZM manual

Incorporation Depth:	DEPI	0	cm

Application Rate:	TAPP	0.8	kg/ha

Application Efficiency:	APPEFF	0.99	fraction

Spray Drift	DRFT	0.063	fraction of application rate applied to pond

Application Date	Date	01-03	dd/mm or dd/mmm or dd-mm or dd-mmm

Interval 1	interval	7	days	Set to 0 or delete line for single app.

Interval 2	interval	7	days	Set to 0 or delete line for single app.

Record 17:	FILTRA	

	IPSCND	1

	UPTKF	

Record 18:	PLVKRT	

	PLDKRT	

	FEXTRC	0.5

Flag for Index Res. Run	IR	IR

Flag for runoff calc.	RUNOFF	total	none, monthly or total(average of
entire run)

set mode = 3

set outfil(4) to Y

set outfil(2) to N

READ ENV C:\models\INPUTS\EXAMSenv\ir298.exv

READ MET C:\models\INPUTS\Metfiles\w93193.dvf

SET YEAR1 = 1961

recall chem 1

chemical name is pyrimethanil

set KPS(1,1) to 2.85

set MWT(1) = 199.26

set HENRY(1) = .000002

set VAPR(1) = .000017

set SOL(1,1) = 121

set KBACW(*,1,1) = 0.00013972487916464

set KBACS(*,1,1) = 2.6447923556164e-005

set QTBAS(*,1,1) = 2

set QTBAW(*,1,1) = 2

READ PRZM P2E-C1.D61

SET STFLO(1,*) = 2.81310577712878

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

RUN

READ PRZM P2E-C1.D62

SET STFLO(1,*) = 2.81310577712878

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

CONTINUE

READ PRZM P2E-C1.D63

SET STFLO(1,*) = 2.81310577712878

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

CONTINUE

READ PRZM P2E-C1.D64

SET STFLO(1,*) = 2.81310577712878

set EVAP(*,*) = 0.0

set NPSFL(*,*)=0.0

set NPSED(*,*)=0.0

set RAIN(*) = 0.0

CONTINUE



Appendix IV

SCIGROW Output Data for Combined Residues (Parent Plus Metabolite)

                         SCIGROW

                          VERSION 2.3

            ENVIRONMENTAL FATE AND EFFECTS DIVISION

                 OFFICE OF PESTICIDE PROGRAMS

             U.S. ENVIRONMENTAL PROTECTION AGENCY

                        SCREENING MODEL

                FOR AQUATIC PESTICIDE EXPOSURE

 

 SciGrow version 2.3

 chemical:pyrimethanil

 time is 10/16/2003  15:51:23

 -----------------------------------------------------------------------
-

  Application      Number of       Total Use    Koc      Soil Aerobic

  rate (lb/acre)  applications   (lb/acre/yr)  (ml/g)   metabolism
(days)

 -----------------------------------------------------------------------
-

      0.715           3.0           2.145      5.60E+01       87.5

 -----------------------------------------------------------------------
-

 groundwater screening cond (ppb) =   4.78E+00 

 ***********************************************************************
*

 

Appendix V

Tabulated Values for Parent (Pyrimethanil) Only Drinking Water
Assessment

PRZM/EXAM  Input Parameters for Parent (Pyrimethanil) Only:

Parameters	Values & Units 	Sources

Molecular Weight	199.26	Product Chemistry

Vapor Pressure 25oC	0.000017 torr	Product Chemistry

Water Solubility @ pH 7.0 and 25oC	121 mg/L	Product Chemistry

Hydrolysis Half-Life (pH 7)	stable	MRID 456459-15

Aerobic Soil Metabolism Half-life 	110 days	MRID 456569-21, MRID
456569-22, MRID 456569-18 (90% confidence interval) 

Anaerobic Aquatic Metabolism 

(total sediment/water system)	1092 days	MRID 456569-23 (half-life times
3 for single value)

Aerobic Aquatic Metabolism 

(total sediment/water system)	158 days	MRID 456570-01 (90% confidence
interval) 

Aqueous Photolysis	stable	MRID 456459-16

Soil Water Partition Coefficient	8.3	Average Kd, MRID 456569-11, MRID
456569-13, MRID 456569-25

Pesticide is Wetted-In	no	Product Label

Crop Management-Florida Strawberries 

   Application Rate	0.8 kg a.i./ha	Product Label

   Number of  Applications	3	Product Label

   Application Interval 	7 days	Product Label

   First Application Date    	October 11	Product Label

   Application Method	Aerial	Product Label

   Spray Efficiency	0.95	EFED

   Spray Drift (Index Res. Scenario)	0.16	EFED



PCA Corrected PRZM/EXAMS Tier II Concentration Values for Parent
(Pyrimethanil) Only:

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摧䓒r؀Acute Exposure from  One in Ten Year Peak Values (ppb)
Non-Cancer Chronic Exposure  from One in Ten Year Annual Mean (ppb)
Average of Yearly Average for Cancer Exposure (ppb)

	Not  Corrected	PCA Corrected	Not  Corrected	PCA Corrected	Not 
Corrected	PCA Corrected

CAgrapes (56%)	11.4	6.4	3.9	2.2	3.5	2.0

ORnuts (63%)	23.9	15.1	6.8	4.3	3.7	2.3

GAonion (38%)	48.5	18.4	9.0	3.4	7.3	2.8

CAplums (56%)	8.2	4.6	2.9	1.6	2.3	1.3

FLstrawberry (38%)	80.5	30.6	12.0	4.6	9.4	3.6



		

Estimation of  Kd and  Koc for Parent (Pyrimethanil) Only:

Soil	% Organic Carbon	Kd (mL/g)	Koc (mL/g)	MRID 

Sandy loam	0.58	2.5	439	456569-25

Loamy sand	1.97	13.5	686	456569-25

Sand	0.75	3.8	500	456569-13*

Loamy sand	2.45	7.8	320	456569-13*

Sandy loam	0.95	2.5	265	456569-13*

Sandy loam	3.5	2.7	75	456569-13*

Sandy clay loam	0.9	3.1	345	456569-13*

Loamy sand	1.32	4.0	299	456569-11*

Sand	3.12	23.4	751	456569-11*

Loamy sand	3.23	17.5	543	456569-11*

Sandy loam	1.58	10.6	682	456569-11*

Median Value

8.3	446

	* supplemental studies conducted with foreign soils 

Environmental Fate Input Parameters for SCIGROW for Pyrimethanil Only:

Parameters	Values & Units 	Sources

Application Rate (3 applications)	0.715 lbs. a.i./acre	Product Label

Organic Carbon Partition Coefficient	75	Lowest Koc from MRID’s 
456569-11, 456569-13, 456569-25

Aerobic Soil Metabolism Half-life 	96.2 days	Mean Calculated from
MRID’s 456569-21, 456569-22, 456569-18



SCI-GROW Groundwater Screening Concentration Values for Pyrimethanil
Only:

Residues Modeled	Groundwater Screening Concentrations (ppb)

 Pyrimethanil Only	4.0



 

 

