  SEQ CHAPTER \h \r 1 

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C.  20460

OFFICE OF              

PREVENTION, PESTICIDES

AND TOXIC SUBSTANCES 

MEMORANDUM

Date:  		2-August-2006

Subject:	Spinosad.  Chronic Dietary Exposure and Risk Assessment. 
Application of Spinosad to Hops and as a Mosquito Larvicide.  PC Code: 
110003.  DP Nos.:  319959 and 330387.  Decision Nos.:  355533 and
367510.  Registration Nos.:  6E7068 and 62719-LGE-GF-1592.

From/To:	Tom Bloem, Chemist

			Registration Action Branch 1/Health Effects Division (RAB1/HED;
7509P)

Through:	Sheila Piper, Chemist

			Dave Soderberg, Chemist

			Dietary Exposure Science Advisory Committee (DESAC) Secondary Review

			George Kramer, Ph.D., Senior Chemist

			RAB1/HED (7509P)

Executive Summary

 conducted using the Dietary Exposure Evaluation Model - Food
Consumption Intake Database (DEEM-FCID™, ver. 2.03; acute and cancer
endpoints were not identified) which incorporates the food consumption
data from the USDA’s Continuing Surveys of Food Intakes by Individuals
(CSFII; 1994-1996 and 1998).  The chronic dietary analyses assumed
average/projected percent crop treated estimates, projected percent head
treated resulting from the dermal and premise treatments to ruminants,
average field trial residues, experimentally-determined processing
factors, and anticipated livestock residues.  For drinking water, the
chronic analyses assumed the modeled Tier 1 chronic surface water
estimate resulting from application of spinosad to turf (4 x 0.4 lb
ai/acre).  The resulting exposure estimates were less than HED’s level
of concern (<100% cPAD).  Children 1-2 years old were the most
highly-exposed population with the chronic exposure estimate occupying
86% of the cPAD.  

I.	Introduction

Dietary risk assessment incorporates both exposure and toxicity of a
given pesticide.  For acute and chronic assessments, the risk is
expressed as a percentage of a maximum acceptable dose (i.e., the dose
which HED has concluded will result in no unreasonable adverse health
effects).  This dose is referred to as the population-adjusted dose
(PAD).  The PAD is equivalent to the reference dose (RfD) divided by the
Food Quality Protection Act (FQPA) Safety Factor (SF).  For acute and
non-cancer chronic exposures, HED is concerned when estimated dietary
risk exceeds 100% of the PAD.  HED is generally concerned when estimated
cancer risk exceeds one in one million (i.e., the risk exceeds 1 x
10-6).  References which discuss the acute and chronic risk assessments
in more detail are available on the EPA/pesticides web site: 
“Available Information on Assessing Exposure from Pesticides, A
User’s Guide,” 6/21/2000, web link:      HYPERLINK
"http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf" 
http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf ; or see
SOP 99.6 (8/20/99).  The most recent dietary risk assessment for
spinosad was conducted by T. Bloem (D319957, 24-Aug-2005).

II.	Residue Information

Residues of Concern in Plants and Livestock:  Table 1 is a summary of
the conclusion made by HED concerning the residues of concern in plants
and livestock.  (D243816, G. Herndon, 3-Mar-1998; D264984, W. Donovan,
14-Jun-2002).  Based on a fish bioconcentration study initially reviewed
by the Environmental Fate and Effects Division (EFED), HED concluded
that the residues of concern in fish/shellfish for tolerance enforcement
are spinosyn A and D (see risk assessment (D316077, in draft) and
residue chemistry summary (D316078 , T. Bloem 2-Aug-2006)); for purposes
of risk assessment, HED concluded that adjustment of the total
radioactive residues (TRRs) in the edible tissues from the 19-ppb
spinosyn A bioconcentration study, for the EFED water concentration
resulting from the mosquito larvicide use, is acceptable.  HED
previously concluded that the residues of concern in drinking water are
spinosyn A and D (D243816, G. Herndon, 3-Mar-1998).  This was based on
the conclusion that spinosad is not persistent.  The EFED has since
reassessed the environmental fate data; this reassessment indicated that
the spinosad transformation products maintain the basic ring structure
of spinosad and that combined spinosad and its transformation products
are stable.  Based on this reassessment, it was concluded that residues
in water should be estimated using a total spinosad residue method (see
risk assessment D316077; in draft). 

Table 1.	Residues for Tolerance Expression and Risk Assessment

Matrix	Residues included in Risk Assessment	Residues included in
Tolerance Expression

Plants	spinosyn A and D	spinosyn A and D

Livestock	spinosyn A and D	spinosyn A and D

Rotational Crops	spinosyn A and D	spinosyn A and D

Drinking Water1	total spinosad	total spinosad

Fish/Shellfish2	adjustment of the TRRs in the edible tissues from the
19-ppb spinosyn A bioconcentration study for the EFED water
concentration resulting from the mosquito larvicide use	spinosyn A and D

1	see HED risk assessment for discussion (D316077; in draft)  

2	HED notes that these conclusions are appropriate for this mosquito
larvicide petition only and will be reevaluated if the petitioner alters
the aquatic application scenario; for discussion concerning the residues
of concern in fish/shellfish see D316078 (T. Bloem, 2-Aug-2006) 

Residues used in the Dietary Exposure Assessment:   Tolerances for
spinosad have been established in/on numerous plant and livestock
commodities (40 CFR 180.495).  As part of two actions, HED recommended
for establishment of the following tolerances for the combined residues
of spinosyn A and D (D316078, T. Bloem, 2-August-2006; D330231, T.
Bloem, 2-August-2006):

Table 2:  Recommended Tolerances 

Commodity	HED Recommended Tolerance (ppm)

hop, dried cones	22

fish	4.0

fish, shellfish, crustacean	4.0

fish, shellfish, mollusk	4.0



Residues Incorporated in the Chronic Dietary Exposure Assessment:  The
chronic analysis incorporated the HED recommended hop tolerance.  For
fish/shellfish, HED concluded that adjustment of the TRRs in the edible
tissues from the 19 ppb spinosyn A bioconcentration study, for the EFED
water concentration resulting from the mosquito larvicide use, should be
used for dietary exposure assessment.  Therefore, based on TRRs of ~0.50
ppm in the edible tissue from the spinosyn A 19-ppb bioconcentration
study, and the 489 ppb water concentration resulting from the mosquito
larvicide use provided by EFED (see below), the dietary exposure
assessment assumed a residue of 12.5 ppb in fish and shellfish (0.50 ppm
x 489 ppb ÷ 19 ppb = 12.5 ppm; see D316078, T. Bloem, 2-Aug-2006). 
Excluding milk (see below), the chronic analysis assumed the residue and
percent crop treated assumptions outlined in the most-ecent spinosad
dietary exposure analysis (D319957, T. Bloem, 24-Aug-2005).  

Residues in milk are derived from consumption of treated feed
commodities by dairy cattle and as a result of dermal application.  The
previous assessment refined the ruminant dietary burden to the extent
possible; therefore, the residue contribution in milk resulting from the
consumption of treated feed commodities was also refined to the extent
possible (D319957, T. Bloem, 24-Aug-2005).  However, the dermal
component of residues in milk assumed the highest daily average from the
ruminant dermal magnitude of the residue study (45080605.der.wpd). 
Since a chronic analysis is being conducted, HED concludes that the
incorporation of average milk residues resulting from dermal treatment
is acceptable.  

The dermal magnitude of the residue study employed the following three
dosing regimens (these dosing regimens mimic the labeled application
sceanrios):  (1) five 2-iter dermal applications of a 400 ppm solution
(7-day retreatment intervl (RTI)); (2) five 5-iter dermal applications
of a 400 ppm solution (21-day RTI); and (3) five 2-mg ai/kg dermal
pour-on applications (14-day RTI).  Figures 1-3 on the following page
are summaries of total spinosyns in milk for each dermal dosing
regiment.  These data indicate that residues in milk peak within ~2 days
of dermal treatment and then decrease and indicate that the 2-mg ai/kg
pour-on dermal treatment results in the highest residues.  Furthermore,
the 2 mg ai/kg treatment regiment resulted in an increase in residues
following each dose.  Based on these data and the current labels which
prohibit more than five consecutive pour-on applications, HED concluded
that averaging residues in the milk samples from the 2-mg ai/kg pour-on
dermal treatment from days 2-61 was appropriate (average = 0.212 ppm). 
The average was then multiplied by the percent dairy cattle head treated
projection provided by BEAD of 23% (see attachment 3 of D319957, T.
Bloem, 24-Aug-2005; 0.212 x 0.23 = 0.049 ppm).  Table 3 is a summary of
the residue in milk resulting from consumption of treated feed (0.097
ppm) and dermal treatment (0.049 ppm).  

HED notes that dermal treatment of cattle is registered and the cattle
residue estimates derive from both oral and dermal exposure.  Dermal
treatment of hog, goat, sheep, and horse is not registered; however,
since premise treatment for these animals is registered and since HED
determined that the cattle dermal magnitude of the residue study may be
used as a conservative estimate of residue following premise treatment,
the residue estimates for these animals are equal to that of cattle
(D321764, T. Bloem, 2-Feb-2006). 

Table 3.  Calculation of Total Residues in Ruminants

	Residue from Diet (ppm)1	Residue from Pour-on (ppm)2	Total Residue
(ppm)

Milk, whole	0.097	0.0492	0.156

Milk, fat	-  estimated as 12.5x the residue in whole milk (D249374, M.
Doherty,14-Jun-1999)	1.822

1	see D319957, T. Bloem, 24-Aug-2005 for derivation of this residue
(based on a dietary burden consisting of average field trial residues
and percent crop treated)

2	see the text above for determination of this residue.  



III.		Drinking Water Data

EFED provided HED with the following total spinosad water concentrations
resulting from the mosquito larvicide application of spinosad (20 x
0.033 lb ai/acre (highest registered/proposed rate); retreatment
interval (RTI) = 7 days; D331271, R. Parker, 28-July-2006):  peak - 489
ppb; annual average 472 ppb.  The water numbers were generated using the
Pesticide Root Zone Model (PRZM 3.12) and Exposure Analysis Modeling
System (EXAMS 2.98.04) models and assumed a 10 cm water column and
static conditions (no flow through or dilution).  The peak estimate was
used for determination of residues in fish/shellfish.  EFED noted that
based on the range of application sites listed on the mosquito larvicide
label, the mosquito larvicide use is not likely to result in exposure
through drinking water that would exceed other crops already assessed. 
Therefore, EFED provided HED with the following surface water (FQPA
Index Reservoir Screening Tool (FIRST)) and ground water (Screening
Concentration In GROund Water (SCIGROW)) drinking water concentrations
resulting from application of spinosad to turf (4 x 0.4 lb ai/acre; RTI
= 7 days; highest registered/proposed rate excluding the mosquito
larvicide use):  surface water - acute 34.5 ppb and chronic 10.5 ppb;
ground water - 1.1 ppb.  Therefore, the dietary exposure assessment
assumed a water concentration of 10.5 ppb for all water sources (direct
and indirect).  

The models and their description are available at the EPA internet site:
  HYPERLINK "http://www.epa.gov/ oppefed1/models/water/" 
http://www.epa.gov/ oppefed1/models/water/ .  

CID™ Program and Consumption Information

The chronic dietary exposure assessments were conducted using the
DEEM-FCID™ (ver. 2.03), which incorporates consumption data from
USDA’s CSFII 1994-1996 and 1998.  The 1994-96, 98 data are based on
the reported consumption of more than 20,000 individuals over two
non-consecutive survey days.  Foods “as consumed” (e.g., apple pie)
are linked to EPA-defined food commodities (e.g. apples, peeled fruit -
cooked; fresh or N/S; baked; or wheat flour - cooked; fresh or N/S,
baked) using publicly available recipe translation files developed
jointly by USDA/ARS and EPA.  Based on analysis of the 1994-96, 98 CSFII
consumption data, which took into account dietary patterns and survey
respondents, HED concluded that it is most appropriate to report risk
for the following population subgroups: the general U.S. population, all
infants (<1 year old), children 1-2, children 3-5, children 6-12, youth
13-19, adults 20-49, females 13-49, and adults 50+ years old.

For chronic dietary exposure assessment, an estimate of the residue
level in each food or food-form (e.g., orange or orange juice) on the
food commodity residue list is multiplied by the average daily
consumption estimate for that food/food form to produce a residue intake
estimate.  The resulting residue intake estimate for each food/food form
is summed with the residue intake estimates for all other food/food
forms on the commodity residue list to arrive at the total average
estimated exposure.  Exposure is expressed in mg/kg body weight/day and
as a percent of the cPAD.  This procedure is performed for each
population subgroup.

V.	Toxicological Information

The HED Hazard Identification Assessment Review Committee (HIARC) met on
22-January-1998 (TXR No.012500) and 11-July-2002 (TXR No. 0050928) to
select endpoints for risk assessment and to evaluate the potential for
increased susceptibility of infants and children from exposure to
spinosad (evaluated according to the February 2002 OPP 10X guidance
document).  HED’s Food Quality Protection Act (FQPA) Safety Factor
Committee (SFC) met on 29-July-2002 and recommended that the 10x safety
factor to account for enhanced sensitivity of infants and children be
reduced to 1x (TXR No. 0051038).  Based on toxicological considerations
(evaluated by FQPA SFC) and the residue assumptions used in the dietary
analyses (evaluated by the reviewer), it was concluded that the FQPA
Safety Factor should be reduced to 1x when assessing chronic dietary
exposures.  Table 4 summarizes the endpoints used for dietary exposure
assessment.   

Table 4:  Summary of Toxicological Doses and Endpoints for Spinosad for
Use in Dietary Exposure Assessment1

Exposure

Scenario	Dose Used in Risk

Assessment, UF	FQPA SF* and Dose for Risk Assessment	Study and
Toxicological Effects

Acute Dietary - 

all populations	None	N/A	No endpoint attributable to a single exposure
was identified.  This risk assessment is not required.

Chronic Dietary -

all populations	NOAEL= 2.7 mg/kg/day

UF =100

cRfD = 0.027 mg/kg/day

	FQPA SF = 1

cPAD = 0.027 mg/kg/day 

	Chronic Toxicity - Dog; NOAEL=2.7 mg/kg

LOAEL = 8.22 mg/kg/day based on vacuolation in glandular cells
(parathyroid) and lymphatic tissues, arteritis, and  increases in serum
alanine aminotransferase, aspartate aminotransferase, and triglycerides
levels 

Cancer	Classification: Not likely to be carcinogen; Q1* = not applicable

1	NOAEL = No Observed Adverse Effect Level; LOAEL = Lowest Observed
Adverse Effect Level; UF = Uncertainty Factor; RfD = Reference Dose; PAD
= Chronic
Popu慬楴湯䄠畤瑳摥䐠獯⁥‽晒⁄⃷兆䅐匠െ嘍⹉刉獥
汵獴䐯獩畣獳潩⁮…潃据畬楳湯൳

The chronic dietary risk estimates were ≤86% of the cPAD and are
therefore less than HED’s level of concern (children 1-2 years old
were the most highly exposed population).  Table 5 is a summary of the
chronic dietary exposure estimates.  

Table 5:	Summary of Chronic Dietary Exposure and Risk (drinking water
included)

Population	cPAD (mg/kg/day)	Exposure (mg/kg/day)	%cPAD

General U.S. Population	0.027	0.009881	37

All Infants (< 1 year old)

0.008751	32

Children 1-2 years old

0.023254	86

Children 3-5 years old

0.019551	72

Children 6-12 years old

0.012974	48

Youth 13-19 years old

0.008480	31

Adults 20-49 years old

0.008523	32

Adults 50+ years old

0.008195	30

Females 13-49 years old

0.007971	30



VII.	Characterization of Inputs/Outputs

≤86% of the cPAD with children 1-2 years old the most highly exposure
population.  A critical commodity analysis conducted for children 1-2
years old revealed that milk (30% cPAD) contributed the most to the
chronic exposure for children 1-2 years old (see attachment 3).  

VIII.	Conclusions

The chronic dietary exposure estimates were ≤86% of the cPAD and are
therefore less than HED’s level of concern (children 1-2 years old
were the most highly exposed subpopulation).

Attachment 1:  DEEM-FCID™ chronic residue file	

Attachment 2:  DEEM-FCID™ chronic exposure estimates 

Attachment 3:  Critical Commodity Analysis

CC with all attachments:  Daniel Rosenblatt/Sidney Jackson, RM 05 (RD;
7505P); George LaRocca/ Bonaventrue Akinlosotu, RM 13 (RD; 7505P)

T. Bloem:S10945:PY:(703)605-0217:7509P

Attachment 1:  DEEM-FCID™ chronic residue file	

Filename: C:\Documents and Settings\tbloem\spinosad\mosquito
larvicide\110003c.R98

Chemical: spinosad

RfD(Chronic): .027 mg/kg bw/day  NOEL(Chronic): 2.7 mg/kg bw/day

RfD(Acute): 0 mg/kg bw/day  NOEL(Acute):  0 mg/kg bw/day

Date created/last modified: 07-27-2006/12:03:17/8          Program ver.
2.03

Comment: 10x interspecies; 10x intraspecies; 1x FQPA SF

------------------------------------------------------------------------
--------

  EPA    Crop                                   Def Res     Adj.Factors 
 Comment

  Code    Grp  Commodity Name                    (ppm)       #1    #2   

-------- ---- -------------------------------  ----------  ------ ------
 -------

95000010 O    Acerola                            1.500000   1.000  1.000
 

95000060 O    Amaranth, grain                    1.000000   1.000  1.000
 

95000160 O    Artichoke, globe                   0.300000   1.000  1.000
 

95000190 O    Asparagus                          0.200000   1.000  1.000
 

95000200 O    Avocado                            0.300000   1.000  0.050
 

95000220 O    Bamboo, shoots                     0.020000   1.000  1.000
 

95000230 O    Banana                             0.250000   1.000  1.000
 

95000231 O    Banana-babyfood                    0.250000   1.000  1.000
 

95000240 O    Banana, dried                      0.250000   3.900  1.000
 

95000241 O    Banana, dried-babyfood             0.250000   3.900  1.000
 

95000540 O    Belgium endive                     0.020000   1.000  1.000
 

95000600 O    Breadfruit                         0.020000   1.000  1.000
 

95000730 O    Cactus                             0.020000   1.000  1.000
 

95000740 O    Canistel                           0.300000   1.000  1.000
 

95000770 O    Carob                              0.020000   1.000  1.000
 

95000890 O    Cherimoya                          0.300000   1.000  1.000
 

95001090 O    Cocoa bean, chocolate              0.020000   1.000  1.000
 

95001100 O    Cocoa bean, powder                 0.020000   1.000  1.000
 

95001110 O    Coconut, meat                      0.020000   1.000  1.000
 

95001111 O    Coconut- meat-babyfood             0.020000   1.000  1.000
 

95001120 O    Coconut, dried                     0.020000   2.100  1.000
 

95001130 O    Coconut, milk                      0.020000   1.000  1.000
 

95001140 O    Coconut, oil                       0.020000   1.000  1.000
 

95001141 O    Coconut, oil-babyfood              0.020000   1.000  1.000
 

95001150 O    Coffee, roasted bean               0.020000   1.000  1.000
 

95001160 O    Coffee, instant                    0.020000   1.000  1.000
 

95001280 O    Cottonseed, oil                    0.020000   1.000  0.050
 

95001281 O    Cottonseed, oil-babyfood           0.020000   1.000  0.050
 

95001300 O    Cranberry                          0.020000   1.000  1.000
 

95001301 O    Cranberry-babyfood                 0.020000   1.000  1.000
 

95001310 O    Cranberry, dried                   0.020000   1.000  1.000
 

95001320 O    Cranberry, juice                   0.020000   1.100  1.000
 

95001321 O    Cranberry, juice-babyfood          0.020000   1.100  1.000
 

95001410 O    Date                               0.020000   1.000  1.000
 

95001510 O    Feijoa                             0.050000   1.000  1.000
 

95001530 O    Fig                                0.100000   1.000  1.000
 

95001540 O    Fig, dried                         0.100000   1.000  1.000
 

95001750 O    Grape                              0.150000   1.000  1.000
 

95001760 O    Grape, juice                       0.150000   3.410  1.000
 

95001761 O    Grape, juice-babyfood              0.150000   3.410  1.000
 

95001770 O    Grape, leaves                      0.150000   1.000  1.000
 

95001780 O    Grape, raisin                      0.150000   1.620  1.000
 

95001790 O    Grape, wine and sherry             0.150000   3.410  1.000
 

95001830 O    Guava                              0.300000   1.000  1.000
 

95001831 O    Guava-babyfood                     0.300000   1.000  1.000
 

95001860 O    Honey                              0.020000   1.000  1.000
 

95001861 O    Honey-babyfood                     0.020000   1.000  1.000
 

95001880 O    Hop                               22.000000   1.000  1.000
 

95001920 O    Jaboticaba                         0.300000   1.000  1.000
 

95001930 O    Jackfruit                          0.020000   1.000  1.000
 

95001950 O    Kiwifruit                          0.020000   1.000  1.000
 

95002090 O    Longan                             0.300000   1.000  1.000
 

95002110 O    Lychee                             0.300000   1.000  1.000
 

95002120 O    Lychee, dried                      0.300000   1.850  1.000
 

95002140 O    Mamey apple                        0.020000   1.000  1.000
 

95002150 O    Mango                              0.300000   1.000  1.000
 

95002151 O    Mango-babyfood                     0.300000   1.000  1.000
 

95002160 O    Mango, dried                       0.300000   1.000  1.000
 

95002170 O    Mango, juice                       0.300000   1.000  1.000
 

95002171 O    Mango, juice-babyfood              0.300000   1.000  1.000
 

95002180 O    Maple, sugar                       0.020000   1.000  1.000
 

95002190 O    Maple syrup                        0.020000   1.000  1.000
 

95002270 O    Mulberry                           0.020000   1.000  1.000
 

95002280 O    Mushroom                           0.020000   1.000  1.000
 

95002350 O    Olive                              0.020000   1.000  1.000
 

95002360 O    Olive, oil                         0.020000   1.000  1.000
 

95002430 O    Palm heart, leaves                 0.020000   1.000  1.000
 

95002440 O    Palm, oil                          0.020000   1.000  1.000
 

95002441 O    Palm, oil-babyfood                 0.020000   1.000  1.000
 

95002450 O    Papaya                             0.300000   1.000  1.000
 

95002451 O    Papaya-babyfood                    0.300000   1.000  1.000
 

95002460 O    Papaya, dried                      0.300000   1.800  1.000
 

95002470 O    Papaya, juice                      0.300000   1.500  1.000
 

95002520 O    Passionfruit                       0.300000   1.000  1.000
 

95002521 O    Passionfruit-babyfood              0.300000   1.000  1.000
 

95002530 O    Passionfruit, juice                0.300000   1.000  1.000
 

95002531 O    Passionfruit, juice-babyfood       0.300000   1.000  1.000
 

95002540 O    Pawpaw                             0.020000   1.000  1.000
 

95002630 O    Peanut                             0.020000   1.000  1.000
 

95002640 O    Peanut, butter                     0.020000   1.890  1.000
 

95002650 O    Peanut, oil                        0.020000   1.000  1.000
 

95002750 O    Peppermint                         3.500000   1.000  1.000
 

95002760 O    Peppermint, oil                    3.500000   1.000  1.000
 

95002770 O    Persimmon                          0.020000   1.000  1.000
 

95002780 O    Pine nut                           0.020000   1.000  1.000
 

95002790 O    Pineapple                          0.020000   1.000  1.000
 

95002791 O    Pineapple-babyfood                 0.020000   1.000  1.000
 

95002800 O    Pineapple, dried                   0.020000   5.000  1.000
 

95002810 O    Pineapple, juice                   0.020000   1.700  1.000
 

95002811 O    Pineapple, juice-babyfood          0.020000   1.700  1.000
 

95002830 O    Plantain                           0.020000   1.000  1.000
 

95002840 O    Plantain, dried                    0.020000   3.900  1.000
 

95002890 O    Pomegranate                        0.020000   1.000  1.000
 

95003060 O    Psyllium, seed                     0.020000   1.000  1.000
 

95003110 O    Quinoa, grain                      0.020000   1.000  1.000
 

95003330 O    Sapote, Mamey                      0.300000   1.000  1.000
 

95003350 O    Seaweed                            0.020000   1.000  1.000
 

95003351 O    Seaweed-babyfood                   0.020000   1.000  1.000
 

95003360 O    Sesame, seed                       0.020000   1.000  1.000
 

95003361 O    Sesame, seed-babyfood              0.020000   1.000  1.000
 

95003370 O    Sesame, oil                        0.020000   1.000  1.000
 

95003371 O    Sesame, oil-babyfood               0.020000   1.000  1.000
 

95003460 O    Soursop                            0.300000   1.000  1.000
 

95003510 O    Spanish lime                       0.300000   1.000  1.000
 

95003520 O    Spearmint                          3.500000   1.000  1.000
 

95003530 O    Spearmint, oil                     3.500000   1.000  1.000
 

95003580 O    Starfruit                          0.300000   1.000  1.000
 

95003590 O    Strawberry                         1.000000   1.000  0.350
 

95003591 O    Strawberry-babyfood                1.000000   1.000  0.350
 

95003600 O    Strawberry, juice                  1.000000   1.000  0.350
 

95003601 O    Strawberry, juice-babyfood         1.000000   1.000  0.350
 

95003610 O    Sugar apple                        0.300000   1.000  1.000
 

95003620 O    Sugarcane, sugar                   0.020000   1.000  1.000
 

95003621 O    Sugarcane, sugar-babyfood          0.020000   1.000  1.000
 

95003630 O    Sugarcane, molasses                0.020000   1.000  1.000
 

95003631 O    Sugarcane, molasses-babyfood       0.020000   1.000  1.000
 

95003680 O    Tamarind                           0.020000   1.000  1.000
 

95003720 O    Tea, dried                         0.020000   1.000  1.000
 

95003730 O    Tea, instant                       0.020000   1.000  1.000
 

95003800 O    Tomato, Tree                       0.020000   1.000  1.000
 

95003900 O    Vinegar                            0.020000   1.000  1.000
 

86010000 O    Water, direct, all sources         0.010500   1.000  1.000
 

86020000 O    Water, indirect, all sources       0.010500   1.000  1.000
 

95003980 O    Watercress                         8.000000   1.000  1.000
 

21000440 M    Beef, meat                         0.116000   1.000  1.000
 

21000441 M    Beef, meat-babyfood                0.116000   1.000  1.000
 

21000450 M    Beef, meat, dried                  0.116000   1.920  1.000
 

21000460 M    Beef, meat byproducts              0.393000   1.000  1.000
 

21000461 M    Beef, meat byproducts-babyfood     0.393000   1.000  1.000
 

21000470 M    Beef, fat                          1.611000   1.000  1.000
 

21000471 M    Beef,fat-babyfood                  1.611000   1.000  1.000
 

21000480 M    Beef, kidney                       0.393000   1.000  1.000
 

21000490 M    Beef, liver                        0.538000   1.000  1.000
 

21000491 M    Beef, liver-babyfood               0.538000   1.000  1.000
 

23001690 M    Goat, meat                         0.116000   1.000  1.000
 

23001700 M    Goat, meat byproducts              0.116000   1.000  1.000
 

23001710 M    Goat, fat                          1.611000   1.000  1.000
 

23001720 M    Goat, kidney                       0.393000   1.000  1.000
 

23001730 M    Goat, liver                        0.538000   1.000  1.000
 

24001890 M    Horse, meat                        0.116000   1.000  1.000
 

28002210 M    Meat, game                         0.116000   1.000  1.000
 

25002900 M    Pork, meat                         0.314000   1.000  1.000
 

25002901 M    Pork, meat-babyfood                0.314000   1.000  1.000
 

25002910 M    Pork, skin                         3.518000   1.000  1.000
 

25002920 M    Pork, meat byproducts              1.052000   1.000  1.000
 

25002921 M    Pork, meat byproducts-babyfood     1.052000   1.000  1.000
 

25002930 M    Pork, fat                          3.518000   1.000  1.000
 

25002931 M    Pork, fat-babyfood                 3.518000   1.000  1.000
 

25002940 M    Pork, kidney                       1.052000   1.000  1.000
 

25002950 M    Pork, liver                        1.357000   1.000  1.000
 

29003120 M    Rabbit, meat                       0.116000   1.000  1.000
 

26003390 M    Sheep, meat                        0.116000   1.000  1.000
 

26003391 M    Sheep, meat-babyfood               0.116000   1.000  1.000
 

26003400 M    Sheep, meat byproducts             0.393000   1.000  1.000
 

26003410 M    Sheep, fat                         1.611000   1.000  1.000
 

26003411 M    Sheep, fat-babyfood                1.611000   1.000  1.000
 

26003420 M    Sheep, kidney                      0.393000   1.000  1.000
 

26003430 M    Sheep, liver                       0.538000   1.000  1.000
 

40000930 P    Chicken, meat                      0.100000   1.000  1.000
 

40000931 P    Chicken, meat-babyfood             0.100000   1.000  1.000
 

40000940 P    Chicken, liver                     0.100000   1.000  1.000
 

40000950 P    Chicken, meat byproducts           0.100000   1.000  1.000
 

40000951 P    Chicken, meat byproducts-babyfoo   0.100000   1.000  1.000
 

40000960 P    Chicken, fat                       1.300000   1.000  1.000
 

40000961 P    Chicken, fat-babyfood              1.300000   1.000  1.000
 

40000970 P    Chicken, skin                      1.300000   1.000  1.000
 

40000971 P    Chicken, skin-babyfood             1.300000   1.000  1.000
 

70001450 P    Egg, whole                         0.300000   1.000  1.000
 

70001451 P    Egg, whole-babyfood                0.300000   1.000  1.000
 

70001460 P    Egg, white                         0.300000   1.000  1.000
 

70001461 P    Egg, white (solids)-babyfood       0.300000   1.000  1.000
 

70001470 P    Egg, yolk                          0.300000   1.000  1.000
 

70001471 P    Egg, yolk-babyfood                 0.300000   1.000  1.000
 

60003010 P    Poultry, other, meat               0.100000   1.000  1.000
 

60003020 P    Poultry, other, liver              0.100000   1.000  1.000
 

60003030 P    Poultry, other, meat byproducts    0.100000   1.000  1.000
 

60003040 P    Poultry, other, fat                1.300000   1.000  1.000
 

60003050 P    Poultry, other, skin               1.300000   1.000  1.000
 

50003820 P    Turkey, meat                       0.100000   1.000  1.000
 

50003821 P    Turkey, meat-babyfood              0.100000   1.000  1.000
 

50003830 P    Turkey, liver                      0.100000   1.000  1.000
 

50003831 P    Turkey, liver-babyfood             0.100000   1.000  1.000
 

50003840 P    Turkey, meat byproducts            0.100000   1.000  1.000
 

50003841 P    Turkey, meat byproducts-babyfood   0.100000   1.000  1.000
 

50003850 P    Turkey, fat                        1.300000   1.000  1.000
 

50003851 P    Turkey, fat-babyfood               1.300000   1.000  1.000
 

50003860 P    Turkey, skin                       1.300000   1.000  1.000
 

50003861 P    Turkey, skin-babyfood              1.300000   1.000  1.000
 

80001570 F    Fish-freshwater finfish           12.500000   1.000  1.000
 

80001580 F    Fish-freshwater finfish, farm ra  12.500000   1.000  1.000
 

80001590 F    Fish-saltwater finfish, tuna      12.500000   1.000  1.000
 

80001600 F    Fish-saltwater finfish, other     12.500000   1.000  1.000
 

80001610 F    Fish-shellfish, crustacean        12.500000   1.000  1.000
 

80001620 F    Fish-shellfish, mollusc           12.500000   1.000  1.000
 

27002220 D    Milk, fat                          1.822000   1.000  1.000
 

27002221 D    Milk, fat - baby food/infant for   1.822000   1.000  1.000
 

27012230 D    Milk, nonfat solids                0.156000   1.000  1.000
 

27012231 D    Milk, nonfat solids-baby food/in   0.156000   1.000  1.000
 

27022240 D    Milk, water                        0.156000   1.000  1.000
 

27022241 D    Milk, water-babyfood/infant form   0.156000   1.000  1.000
 

27032251 D    Milk, sugar (lactose)-baby food/   0.156000   1.000  1.000
 

01030150 1CD  Arrowroot, flour                   0.100000   1.000  1.000
 

01030151 1CD  Arrowroot, flour-babyfood          0.100000   1.000  1.000
 

01030170 1CD  Artichoke, Jerusalem               0.100000   1.000  1.000
 

01010500 1AB  Beet, garden, roots                0.100000   1.000  1.000
 

01010501 1AB  Beet, garden, roots-babyfood       0.100000   1.000  1.000
 

01010520 1A   Beet, sugar                        0.100000   1.000  1.000
 

01010521 1A   Beet, sugar-babyfood               0.100000   1.000  1.000
 

01010530 1A   Beet, sugar, molasses              0.750000   1.000  1.000
 

01010531 1A   Beet, sugar, molasses-babyfood     0.750000   1.000  1.000
 

01010670 1AB  Burdock                            0.100000   1.000  1.000
 

01010780 1AB  Carrot                             0.100000   1.000  1.000
 

01010781 1AB  Carrot-babyfood                    0.100000   1.000  1.000
 

01010790 1AB  Carrot, juice                      0.100000   1.000  1.000
 

01030820 1CD  Cassava                            0.100000   1.000  1.000
 

01030821 1CD  Cassava-babyfood                   0.100000   1.000  1.000
 

01010840 1AB  Celeriac                           0.100000   1.000  1.000
 

01011000 1AB  Chicory, roots                     0.100000   1.000  1.000
 

01031390 1CD  Dasheen, corm                      0.100000   1.000  1.000
 

01031660 1CD  Ginger                             0.100000   1.000  1.000
 

01031661 1CD  Ginger-babyfood                    0.100000   1.000  1.000
 

01031670 1CD  Ginger, dried                      0.100000   1.000  1.000
 

01011680 1AB  Ginseng, dried                     0.100000   1.000  1.000
 

01011900 1AB  Horseradish                        0.100000   1.000  1.000
 

01012500 1AB  Parsley, turnip rooted             0.100000   1.000  1.000
 

01012510 1AB  Parsnip                            0.100000   1.000  1.000
 

01012511 1AB  Parsnip-babyfood                   0.100000   1.000  1.000
 

01032960 1C   Potato, chips                      0.100000   1.000  0.050
 

01032970 1C   Potato, dry (granules/ flakes)     0.100000   6.500  0.050
 

01032971 1C   Potato, dry (granules/ flakes)-b   0.100000   6.500  0.050
 

01032980 1C   Potato, flour                      0.100000   1.000  0.050
 

01032981 1C   Potato, flour-babyfood             0.100000   1.000  0.050
 

01032990 1C   Potato, tuber, w/peel              0.100000   1.000  0.050
 

01032991 1C   Potato, tuber, w/peel-babyfood     0.100000   1.000  0.050
 

01033000 1C   Potato, tuber, w/o peel            0.100000   1.000  0.050
 

01033001 1C   Potato, tuber, w/o peel-babyfood   0.100000   1.000  0.050
 

01013140 1AB  Radish, roots                      0.100000   1.000  1.000
 

01013160 1AB  Radish, Oriental, roots            0.100000   1.000  1.000
 

01013270 1AB  Rutabaga                           0.100000   1.000  1.000
 

01013310 1AB  Salsify, roots                     0.100000   1.000  1.000
 

01033660 1CD  Sweet potato                       0.100000   1.000  1.000
 

01033661 1CD  Sweet potato-babyfood              0.100000   1.000  1.000
 

01033710 1CD  Tanier, corm                       0.100000   1.000  1.000
 

01033870 1CD  Turmeric                           0.100000   1.000  1.000
 

01013880 1AB  Turnip, roots                      0.100000   1.000  1.000
 

01034060 1CD  Yam, true                          0.100000   1.000  1.000
 

01034070 1CD  Yam bean                           0.100000   1.000  1.000
 

02000510 2    Beet, garden, tops                10.000000   1.000  1.000
 

02001010 2    Chicory, tops                     10.000000   1.000  1.000
 

02001400 2    Dasheen, leaves                   10.000000   1.000  1.000
 

02003150 2    Radish, tops                      10.000000   1.000  1.000
 

02003170 2    Radish, Oriental, tops            10.000000   1.000  1.000
 

02003320 2    Salsify, tops                     10.000000   1.000  1.000
 

03001640 3    Garlic                             0.100000   1.000  1.000
 

03001650 3    Garlic, dried                      0.100000   1.000  1.000
 

03001651 3    Garlic, dried-babyfood             0.100000   1.000  1.000
 

03001980 3    Leek                               0.100000   1.000  1.000
 

03002370 3    Onion, dry bulb                    0.100000   1.000  1.000
 

03002371 3    Onion, dry bulb-babyfood           0.100000   1.000  1.000
 

03002380 3    Onion, dry bulb, dried             0.100000   9.000  1.000
 

03002381 3    Onion, dry bulb, dried-babyfood    0.100000   9.000  1.000
 

03002390 3    Onion, green                       2.000000   1.000  1.000
 

03003380 3    Shallot                            0.100000   1.000  1.000
 

04010050 4A   Amaranth, leafy                    8.000000   1.000  1.000
 

04010180 4A   Arugula                            8.000000   1.000  1.000
 

04020760 4B   Cardoon                            8.000000   1.000  1.000
 

04020850 4B   Celery                             8.000000   1.000  0.500
 

04020851 4B   Celery-babyfood                    8.000000   1.000  1.000
 

04020860 4B   Celery, juice                      8.000000   1.000  1.000
 

04020870 4B   Celtuce                            8.000000   1.000  1.000
 

04011040 4A   Chrysanthemum, garland             8.000000   1.000  1.000
 

04011330 4A   Cress, garden                      8.000000   1.000  1.000
 

04011340 4A   Cress, upland                      8.000000   1.000  1.000
 

04011380 4A   Dandelion, leaves                  8.000000   1.000  1.000
 

04011500 4A   Endive                             8.000000   1.000  1.000
 

04021520 4B   Fennel, Florence                   8.000000   1.000  1.000
 

04012040 4A   Lettuce, head                      8.000000   1.000  0.500
 

04012050 4A   Lettuce, leaf                      8.000000   1.000  0.500
 

04012480 4A   Parsley, leaves                    8.000000   1.000  1.000
 

04013130 4A   Radicchio                          8.000000   1.000  1.000
 

04023220 4B   Rhubarb                            8.000000   1.000  1.000
 

04013550 4A   Spinach                            8.000000   1.000  0.300
 

04013551 4A   Spinach-babyfood                   8.000000   1.000  0.300
 

04023670 4B   Swiss chard                        8.000000   1.000  1.000
 

05010610 5A   Broccoli                           2.000000   1.000  0.400
 

05010611 5A   Broccoli-babyfood                  2.000000   1.000  0.400
 

05010620 5A   Broccoli, Chinese                  2.000000   1.000  1.000
 

05020630 5B   Broccoli raab                     10.000000   1.000  1.000
 

05010640 5A   Brussels sprouts                   2.000000   1.000  0.150
 

05010690 5A   Cabbage                            2.000000   1.000  0.300
 

05020700 5B   Cabbage, Chinese, bok choy        10.000000   1.000  1.000
 

05010710 5A   Cabbage, Chinese, napa             2.000000   1.000  1.000
 

05010720 5A   Cabbage, Chinese, mustard          2.000000   1.000  1.000
 

05010830 5A   Cauliflower                        2.000000   1.000  0.450
 

05021170 5B   Collards                          10.000000   1.000  0.250
 

05021940 5B   Kale                              10.000000   1.000  0.300
 

05011960 5A   Kohlrabi                           2.000000   1.000  1.000
 

05022290 5B   Mustard greens                    10.000000   1.000  0.150
 

05023180 5B   Rape greens                       10.000000   1.000  1.000
 

05023890 5B   Turnip, greens                    10.000000   1.000  0.050
 

06030300 6C   Bean, black, seed                  0.020000   1.000  1.000
 

06020310 6B   Bean, broad, succulent             0.020000   1.000  1.000
 

06030320 6C   Bean, broad, seed                  0.020000   1.000  1.000
 

06020330 6B   Bean, cowpea, succulent            0.020000   1.000  1.000
 

06030340 6C   Bean, cowpea, seed                 0.020000   1.000  1.000
 

06030350 6C   Bean,  great northern, seed        0.020000   1.000  1.000
 

06030360 6C   Bean, kidney, seed                 0.020000   1.000  1.000
 

06020370 6B   Bean, lima, succulent              0.020000   1.000  1.000
 

06030380 6C   Bean, lima, seed                   0.020000   1.000  1.000
 

06030390 6C   Bean, mung, seed                   0.020000   1.000  1.000
 

06030400 6C   Bean, navy, seed                   0.020000   1.000  1.000
 

06030410 6C   Bean, pink, seed                   0.020000   1.000  1.000
 

06030420 6C   Bean, pinto, seed                  0.020000   1.000  1.000
 

06010430 6A   Bean, snap, succulent              0.300000   1.000  1.000
 

06010431 6A   Bean, snap, succulent-babyfood     0.300000   1.000  1.000
 

06030980 6C   Chickpea, seed                     0.020000   1.000  1.000
 

06030981 6C   Chickpea, seed-babyfood            0.020000   1.000  1.000
 

06030990 6C   Chickpea, flour                    0.020000   1.000  1.000
 

06031820 6C   Guar, seed                         0.020000   1.000  1.000
 

06031821 6C   Guar, seed-babyfood                0.020000   1.000  1.000
 

06032030 6C   Lentil, seed                       0.020000   1.000  1.000
 

06022550 6B   Pea, succulent                     0.020000   1.000  1.000
 

06022551 6B   Pea, succulent-babyfood            0.020000   1.000  1.000
 

06032560 6C   Pea, dry                           0.020000   1.000  1.000
 

06032561 6C   Pea, dry-babyfood                  0.020000   1.000  1.000
 

06012570 6A   Pea, edible podded, succulent      0.300000   1.000  1.000
 

06032580 6C   Pea, pigeon, seed                  0.020000   1.000  1.000
 

06022590 6B   Pea, pigeon, succulent             0.020000   1.000  1.000
 

06003470 6    Soybean, seed                      0.020000   1.000  1.000
 

06003480 6    Soybean, flour                     0.020000   1.000  1.000
 

06003481 6    Soybean, flour-babyfood            0.020000   1.000  1.000
 

06003490 6    Soybean, soy milk                  0.020000   1.000  1.000
 

06003491 6    Soybean, soy milk-babyfood or in   0.020000   1.000  1.000
 

06003500 6    Soybean, oil                       0.020000   1.000  1.000
 

06003501 6    Soybean, oil-babyfood              0.020000   1.000  1.000
 

08001480 8    Eggplant                           0.400000   1.000  0.150
 

08002340 8    Okra                               0.400000   1.000  1.000
 

08002700 8    Pepper, bell                       0.400000   1.000  0.350
 

08002701 8    Pepper, bell-babyfood              0.400000   1.000  0.350
 

08002710 8    Pepper, bell, dried                0.400000   1.000  0.350
 

08002711 8    Pepper, bell, dried-babyfood       0.400000   1.000  0.350
 

08002720 8    Pepper, nonbell                    0.400000   1.000  0.350
 

08002721 8    Pepper, nonbell-babyfood           0.400000   1.000  0.350
 

08002730 8    Pepper, nonbell, dried             0.400000   1.000  0.350
 

08003740 8    Tomatillo                          0.400000   1.000  1.000
 

08003750 8    Tomato                             0.400000   1.000  0.200
 

08003751 8    Tomato-babyfood                    0.400000   1.000  0.200
 

08003760 8    Tomato, paste                      0.400000   5.400  0.200
 

08003761 8    Tomato, paste-babyfood             0.400000   5.400  0.200
 

08003770 8    Tomato, puree                      0.400000   3.300  0.200
 

08003771 8    Tomato, puree-babyfood             0.400000   3.300  0.200
 

08003780 8    Tomato, dried                      0.400000  14.300  0.200
 

08003781 8    Tomato, dried-babyfood             0.400000  14.300  0.200
 

08003790 8    Tomato, juice                      0.400000   1.500  0.200
 

09020210 9B   Balsam pear                        0.300000   1.000  1.000
 

09010750 9A   Cantaloupe                         0.300000   1.000  0.100
 

09010800 9A   Casaba                             0.300000   1.000  1.000
 

09020880 9B   Chayote, fruit                     0.300000   1.000  1.000
 

09021020 9B   Chinese waxgourd                   0.300000   1.000  1.000
 

09021350 9B   Cucumber                           0.300000   1.000  0.200
 

09011870 9A   Honeydew melon                     0.300000   1.000  1.000
 

09023080 9B   Pumpkin                            0.300000   1.000  1.000
 

09023090 9B   Pumpkin, seed                      0.300000   1.000  1.000
 

09023560 9B   Squash, summer                     0.300000   1.000  0.100
 

09023561 9B   Squash, summer-babyfood            0.300000   1.000  0.100
 

09023570 9B   Squash, winter                     0.300000   1.000  0.100
 

09023571 9B   Squash, winter-babyfood            0.300000   1.000  0.100
 

09013990 9A   Watermelon                         0.300000   1.000  0.050
 

09014000 9A   Watermelon, juice                  0.300000   1.000  0.050
 

10001060 10   Citrus citron                      0.300000   1.000  0.050
 

10001070 10   Citrus hybrids                     0.300000   1.000  0.050
 

10001080 10   Citrus, oil                        3.000000   1.000  0.050
 

10001800 10   Grapefruit                         0.300000   1.000  0.050
 

10001810 10   Grapefruit, juice                  0.300000   2.100  0.050
 

10001970 10   Kumquat                            0.300000   1.000  0.050
 

10001990 10   Lemon                              0.300000   1.000  0.100
 

10002000 10   Lemon, juice                       0.300000   2.000  0.100
 

10002001 10   Lemon, juice-babyfood              0.300000   2.000  0.100
 

10002010 10   Lemon, peel                        0.300000   1.000  0.100
 

10002060 10   Lime                               0.300000   1.000  0.050
 

10002070 10   Lime, juice                        0.300000   2.000  0.050
 

10002071 10   Lime, juice-babyfood               0.300000   2.000  0.050
 

10002400 10   Orange                             0.300000   1.000  0.100
 

10002410 10   Orange, juice                      0.300000   1.800  0.100
 

10002411 10   Orange, juice-babyfood             0.300000   1.800  0.100
 

10002420 10   Orange, peel                       0.300000   1.000  0.100
 

10003070 10   Pummelo                            0.300000   1.000  0.050
 

10003690 10   Tangerine                          0.300000   1.000  0.100
 

10003700 10   Tangerine, juice                   0.300000   2.300  0.100
 

11000070 11   Apple, fruit with peel             0.200000   1.000  0.300
 

11000080 11   Apple, peeled fruit                0.200000   1.000  0.300
 

11000081 11   Apple, peeled fruit-babyfood       0.200000   1.000  0.300
 

11000090 11   Apple, dried                       0.200000   8.000  0.300
 

11000091 11   Apple, dried-babyfood              0.200000   8.000  0.300
 

11000100 11   Apple, juice                       0.200000   1.300  0.300
 

11000101 11   Apple, juice-babyfood              0.200000   1.300  0.300
 

11000110 11   Apple, sauce                       0.200000   1.000  0.300
 

11000111 11   Apple, sauce-babyfood              0.200000   1.000  0.300
 

11001290 11   Crabapple                          0.200000   1.000  1.000
 

11002100 11   Loquat                             0.200000   1.000  1.000
 

11002660 11   Pear                               0.200000   1.000  0.100
 

11002661 11   Pear-babyfood                      0.200000   1.000  0.100
 

11002670 11   Pear, dried                        0.200000   6.250  0.100
 

11002680 11   Pear, juice                        0.200000   1.000  0.100
 

11002681 11   Pear, juice-babyfood               0.200000   1.000  0.100
 

11003100 11   Quince                             0.200000   1.000  1.000
 

12000120 12   Apricot                            0.200000   1.000  0.100
 

12000121 12   Apricot-babyfood                   0.200000   1.000  0.100
 

12000130 12   Apricot, dried                     0.200000   6.000  0.100
 

12000140 12   Apricot, juice                     0.200000   1.000  0.100
 

12000141 12   Apricot, juice-babyfood            0.200000   1.000  0.100
 

12000900 12   Cherry                             0.200000   1.000  0.250
 

12000901 12   Cherry-babyfood                    0.200000   1.000  0.250
 

12000910 12   Cherry, juice                      0.200000   1.500  0.250
 

12000911 12   Cherry, juice-babyfood             0.200000   1.500  0.250
 

12002300 12   Nectarine                          0.200000   1.000  0.300
 

12002600 12   Peach                              0.200000   1.000  0.050
 

12002601 12   Peach-babyfood                     0.200000   1.000  0.050
 

12002610 12   Peach, dried                       0.200000   7.000  0.050
 

12002611 12   Peach, dried-babyfood              0.200000   7.000  0.050
 

12002620 12   Peach, juice                       0.200000   1.000  0.050
 

12002621 12   Peach, juice-babyfood              0.200000   1.000  0.050
 

12002850 12   Plum                               0.200000   1.000  0.100
 

12002851 12   Plum-babyfood                      0.200000   1.000  0.100
 

12002860 12   Plum, prune, fresh                 0.200000   1.000  0.100
 

12002861 12   Plum, prune, fresh-babyfood        0.200000   1.000  0.100
 

12002870 12   Plum, prune, dried                 0.200000   5.000  0.100
 

12002871 12   Plum, prune, dried-babyfood        0.200000   5.000  0.100
 

12002880 12   Plum, prune, juice                 0.200000   1.400  0.100
 

12002881 12   Plum, prune, juice-babyfood        0.200000   1.400  0.100
 

13010550 13A  Blackberry                         0.700000   1.000  1.000
 

13010560 13A  Blackberry, juice                  0.700000   1.000  1.000
 

13010561 13A  Blackberry, juice-babyfood         0.700000   1.000  1.000
 

13020570 13B  Blueberry                          0.250000   1.000  1.000
 

13020571 13B  Blueberry-babyfood                 0.250000   1.000  1.000
 

13010580 13A  Boysenberry                        0.700000   1.000  1.000
 

13021360 13B  Currant                            0.250000   1.000  1.000
 

13021370 13B  Currant, dried                     0.250000   1.000  1.000
 

13011420 13A  Dewberry                           0.700000   1.000  1.000
 

13021490 13B  Elderberry                         0.250000   1.000  1.000
 

13021740 13B  Gooseberry                         0.250000   1.000  1.000
 

13021910 13B  Huckleberry                        0.250000   1.000  1.000
 

13012080 13A  Loganberry                         0.700000   1.000  1.000
 

13013200 13A  Raspberry                          0.700000   1.000  1.000
 

13013201 13A  Raspberry-babyfood                 0.700000   1.000  1.000
 

13013210 13A  Raspberry, juice                   0.700000   1.000  1.000
 

13013211 13A  Raspberry, juice-babyfood          0.700000   1.000  1.000
 

14000030 14   Almond                             0.020000   1.000  0.050
 

14000031 14   Almond-babyfood                    0.020000   1.000  0.050
 

14000040 14   Almond, oil                        0.020000   1.000  0.050
 

14000041 14   Almond, oil-babyfood               0.020000   1.000  0.050
 

14000590 14   Brazil nut                         0.020000   1.000  1.000
 

14000680 14   Butternut                          0.020000   1.000  1.000
 

14000810 14   Cashew                             0.020000   1.000  1.000
 

14000920 14   Chestnut                           0.020000   1.000  1.000
 

14001550 14   Filbert                            0.020000   1.000  1.000
 

14001560 14   Filbert, oil                       0.020000   1.000  1.000
 

14001850 14   Hickory nut                        0.020000   1.000  1.000
 

14002130 14   Macadamia nut                      0.020000   1.000  1.000
 

14002690 14   Pecan                              0.020000   1.000  1.000
 

14002820 14   Pistachio                          0.020000   1.000  1.000
 

14003910 14   Walnut                             0.020000   1.000  1.000
 

15000250 15   Barley, pearled barley             0.652000   1.000  1.000
 

15000251 15   Barley, pearled barley-babyfood    0.652000   1.000  1.000
 

15000260 15   Barley, flour                      0.652000   1.000  1.000
 

15000261 15   Barley, flour-babyfood             0.652000   1.000  1.000
 

15000270 15   Barley, bran                       0.652000   1.000  1.000
 

15000650 15   Buckwheat                          1.500000   1.000  1.000
 

15000660 15   Buckwheat, flour                   1.500000   1.000  1.000
 

15001200 15   Corn, field, flour                 0.510000   0.220  1.000
 

15001201 15   Corn, field, flour-babyfood        0.510000   0.220  1.000
 

15001210 15   Corn, field, meal                  0.510000   0.260  1.000
 

15001211 15   Corn, field, meal-babyfood         0.510000   0.260  1.000
 

15001220 15   Corn, field, bran                  0.510000   1.000  1.000
 

15001230 15   Corn, field, starch                0.510000   0.010  1.000
 

15001231 15   Corn, field, starch-babyfood       0.510000   0.010  1.000
 

15001240 15   Corn, field, syrup                 0.510000   1.500  1.000
 

15001241 15   Corn, field, syrup-babyfood        0.510000   1.500  1.000
 

15001250 15   Corn, field, oil                   0.510000   1.200  1.000
 

15001251 15   Corn, field, oil-babyfood          0.510000   1.200  1.000
 

15001260 15   Corn, pop                          0.510000   1.000  1.000
 

15001270 15   Corn, sweet                        0.020000   1.000  0.010
 

15001271 15   Corn, sweet-babyfood               0.020000   1.000  0.010
 

15002260 15   Millet, grain                      1.500000   1.000  1.000
 

15002310 15   Oat, bran                          0.495000   1.000  1.000
 

15002320 15   Oat, flour                         0.495000   1.000  1.000
 

15002321 15   Oat, flour-babyfood                0.495000   1.000  1.000
 

15002330 15   Oat, groats/rolled oats            0.495000   1.000  1.000
 

15002331 15   Oat, groats/rolled oats-babyfood   0.495000   1.000  1.000
 

15003230 15   Rice, white                        0.664000   1.000  1.000
 

15003231 15   Rice, white-babyfood               0.664000   1.000  1.000
 

15003240 15   Rice, brown                        0.664000   1.000  1.000
 

15003241 15   Rice, brown-babyfood               0.664000   1.000  1.000
 

15003250 15   Rice, flour                        0.664000   1.000  1.000
 

15003251 15   Rice, flour-babyfood               0.664000   1.000  1.000
 

15003260 15   Rice, bran                         0.664000   1.000  1.000
 

15003261 15   Rice, bran-babyfood                0.664000   1.000  1.000
 

15003280 15   Rye, grain                         1.500000   1.000  1.000
 

15003290 15   Rye, flour                         1.500000   1.000  1.000
 

15003440 15   Sorghum, grain                     1.500000   1.000  1.000
 

15003450 15   Sorghum, syrup                     1.500000   1.000  1.000
 

15003810 15   Triticale, flour                   1.500000   1.000  1.000
 

15003811 15   Triticale, flour-babyfood          1.500000   1.000  1.000
 

15004010 15   Wheat, grain                       0.551000   1.000  1.000
 

15004011 15   Wheat, grain-babyfood              0.551000   1.000  1.000
 

15004020 15   Wheat, flour                       0.551000   0.340  1.000
 

15004021 15   Wheat, flour-babyfood              0.551000   0.340  1.000
 

15004030 15   Wheat, germ                        0.551000   0.720  1.000
 

15004040 15   Wheat, bran                        0.551000   1.000  1.000
 

15004050 15   Wild rice                          1.500000   1.000  1.000
 

19010280 19A  Basil, fresh leaves                3.000000   1.000  1.000
 

19010281 19A  Basil, fresh leaves-babyfood       3.000000   1.000  1.000
 

19010290 19A  Basil, dried leaves               22.000000   1.000  1.000
 

19010291 19A  Basil, dried leaves-babyfood      22.000000   1.000  1.000
 

19011030 19A  Chive                             22.000000   1.000  1.000
 

19021050 19B  Cinnamon                           0.020000   1.000  1.000
 

19021051 19B  Cinnamon-babyfood                  0.020000   1.000  1.000
 

19011180 19A  Coriander, leaves                  8.000000   1.000  1.000
 

19011181 19A  Coriander, leaves-babyfood         8.000000   1.000  1.000
 

19021190 19B  Coriander, seed                    0.020000   1.000  1.000
 

19021191 19B  Coriander, seed-babyfood           0.020000   1.000  1.000
 

19021430 19B  Dill, seed                         0.020000   1.000  1.000
 

19011440 19A  Dillweed                          22.000000   1.000  1.000
 

19011840 19A  Herbs, other                      22.000000   1.000  1.000
 

19011841 19A  Herbs, other-babyfood             22.000000   1.000  1.000
 

19012020 19A  Lemongrass                        22.000000   1.000  1.000
 

19012200 19A  Marjoram                          22.000000   1.000  1.000
 

19012201 19A  Marjoram-babyfood                 22.000000   1.000  1.000
 

19012490 19A  Parsley, dried leaves             22.000000   1.000  1.000
 

19012491 19A  Parsley, dried leaves-babyfood    22.000000   1.000  1.000
 

19022740 19B  Pepper, black and white            0.020000   1.000  1.000
 

19022741 19B  Pepper, black and white-babyfood   0.020000   1.000  1.000
 

19013340 19A  Savory                            22.000000   1.000  1.000
 

19023540 19B  Spices, other                      0.020000   1.000  1.000
 

19023541 19B  Spices, other-babyfood             0.020000   1.000  1.000
 

Attachment 2:  DEEM-FCID™ chronic exposure estimates 

U.S. Environmental Protection Agency                                
Ver. 2.00

DEEM-FCID Chronic analysis for SPINOSAD                         (1994-98
data)

Residue file name: C:\Documents and Settings\tbloem\spinosad\mosquito
larvicide\110003c.R98

                                                     Adjustment factor
#2 used.

Analysis Date 08-01-2006/11:49:59     Residue file dated:
08-01-2006/11:49:16/8

Reference dose (RfD, Chronic) = .027 mg/kg bw/day

COMMENT 1: 10x interspecies; 10x intraspecies; 1x FQPA SF

========================================================================
======

                    Total exposure by population subgroup

------------------------------------------------------------------------
------

                                                    Total Exposure

                                        
-----------------------------------

          Population                         mg/kg             Percent
of   

           Subgroup                       body wt/day             Rfd   
   

--------------------------------------   -------------      
---------------

U.S. Population (total)                     0.009881               
36.6%

U.S. Population (spring season)             0.010375               
38.4%

U.S. Population (summer season)             0.009736               
36.1%

U.S. Population (autumn season)             0.009745               
36.1%

U.S. Population (winter season)             0.009675               
35.8%

Northeast region                            0.010819               
40.1%

Midwest region                              0.009452               
35.0%

Southern region                             0.009120               
33.8%

Western region                              0.010706               
39.7%

Hispanics                                   0.010061               
37.3%

Non-hispanic whites                         0.009418               
34.9%

Non-hispanic blacks                         0.010464               
38.8%

Non-hisp/non-white/non-black                0.015389               
57.0%

All infants (< 1 year)                      0.008751               
32.4%

Nursing infants                             0.003413               
12.6%

Non-nursing infants                         0.010777               
39.9%

Children 1-6  yrs                           0.020170               
74.7%

Children 7-12 yrs                           0.012455               
46.1%

Females 13-19 (not preg or nursing)         0.007615               
28.2%

Females 20+ (not preg or nursing)           0.008056               
29.8%

Females 13-50 yrs                           0.008326               
30.8%

Females 13+ (preg/not nursing)              0.007696               
28.5%

Females 13+ (nursing)                       0.008780               
32.5%

Males 13-19 yrs                             0.009306               
34.5%

Males 20+ yrs                               0.008781               
32.5%

Seniors 55+                                 0.008121               
30.1%

Children 1-2 yrs                            0.023254               
86.1%

Children 3-5 yrs                            0.019551               
72.4%

Children 6-12 yrs                           0.012974               
48.1%

Youth 13-19 yrs                             0.008480               
31.4%

Adults 20-49 yrs                            0.008523               
31.6%

Adults 50+ yrs                              0.008195               
30.4%

Females 13-49 yrs                           0.007971               
29.5%

------------------------------------------------------------------------
------

Attachment 3:  Critical Commodity Analysis

U.S. Environmental Protection Agency                                
Ver. 2.00

DEEM-FCID Chronic analysis for SPINOSAD                         (1994-98
data)

Residue file name:
C:䑜捯浵湥獴愠摮匠瑥楴杮屳扴潬浥獜楰潮慳層潭煳極
潴氠牡楶楣敤ㅜ〱〰挳刮㠹‍†††††††††††
†††††††††††††††摁番瑳敭瑮映捡潴⁲
㈣甠敳⹤䄍慮祬楳⁳慄整〠ⴸ㄰㈭〰⼶ㄱ㔺㨳ㄳ††删
獥摩敵映汩⁥慤整㩤〠ⴸ㄰㈭〰⼶ㄱ㐺㨹㘱㠯



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Reference dose (RfD, Chronic) = .027 mg/kg bw/day

COMMENT 1: 10x interspecies; 10x intraspecies; 1x FQPA SF

========================================================================
======

                 Critical Commodity Contribution Analysis for

                               Children 1-2 yrs

                 Total Exposure =.0232539 mg/kg bw/day

            Crop groups with total exposure contribution > 5%

              Foods/Foodforms with exposure contribution > 5%

------------------------------------------------------------------------
------

Crop group                               ----------Exposure
Analysis-------

   Food                                     mg/kg     % of Total  
Percent 

      Foodform                           body wt/day   Exposure    of
RfD  

--------------------------------------   -----------  ---------- 
---------

Crop Group = (O)  Other

  Total for crop group                     0.0022282      9.58%      
8.25%

Crop Group = (M)  Meat

  Total for crop group                     0.0015045      6.47%      
5.57%

Crop Group = (F)  Fish

   Fish-saltwater finfish, other (80001600):

        FoodForm N/S                       0.0016521      7.10%      
6.12%

--------------------------------------   -----------  ---------- 
---------

  Total for crop group                     0.0034647     14.90%     
12.83%

Crop Group = (D)  Dairy Products

   Milk, fat (27002220):

        FoodForm N/S                       0.0026175     11.26%      
9.69%

   Milk, water (27022240):

        FoodForm N/S                       0.0049210     21.16%     
18.23%

--------------------------------------   -----------  ---------- 
---------

  Total for crop group                     0.0081191     34.92%     
30.07%

Crop Group = (4)  Leafy Vegetables (except Brassica)

  Total for crop group                     0.0011855      5.10%      
4.39%

Crop Group = (15) Cereal Grains

   Corn, field, syrup (15001240):

        FoodForm N/S                       0.0015039      6.47%      
5.57%

--------------------------------------   -----------  ---------- 
---------

  Total for crop group                     0.0032574     14.01%     
12.06%

Total for crop groups listed above:        0.0197595     84.97%     
73.2%

------------------------------------------------------------------------
------               

Spinosad	Dietary Exposure and Risk Assessment	D319959

Page   PAGE  1  of   NUMPAGES  19 

Spinosad	Dietary Exposure Assessment	D319959 

 

