MEMORANDUM
SUBJECT:
Bentazon.
List
A
Reregistration
Case
No.
0182,
Chemical
No.
103901.
Product
and
Residue
Chemistry
Chapters
for
the
Reregistration
Eligibility
Decision
Document
(
RED).
CBRS
No.
11440;
DP
BARCODE
D188712.

FROM:
Paula
A.
Deschamp,
Section
Head
Reregistration
Section
I
Chemistry
Branch
II:
Reregistration
Support
Health
Effects
Division
(
7509C)

THRU:
Edward
Zager,
Chief
Chemistry
Branch
II:
Reregistration
Support
Health
Effects
Division
(
7509C)

TO:
Lois
Rossi,
Chief
Reregistration
Branch
Special
Review
and
Reregistration
Division
(
7508W)

and
Esther
Saito,
Chief
Chemical
Coordination
Branch
Health
Effects
Division
(
7509C)

Attached
are
the
Product
and
Residue
Chemistry
Chapters
for
the
Bentazon
RED.
This
information
was
compiled
by
Dynamac
Corporation
under
supervision
of
CBRS,
HED.
These
chapters
have
undergone
secondary
review
in
CBRS
and
have
been
revised
to
reflect
Branch
policies.

All
product
chemistry
data
(
received
by
CBRS
through
1/
25/
94)
submitted
in
support
of
the
reregistration
of
bentazon
manufacturing­
use
products
have
been
reviewed.
Provided
that
the
registrant
submits
the
data
required
in
the
attached
data
summary
tables
and
either
certifies
that
the
suppliers
of
starting
materials
and
the
manufacturing
processes
for
the
bentazon
sodium
salt
products
have
not
changed
since
the
last
comprehensive
product
chemistry
review
or
submits
a
complete
updated
product
chemistry
data
package,
CBRS
has
no
objections
to
the
reregistration
of
bentazon
with
respect
to
product
chemistry
data.

All
residue
chemistry
data
(
received
by
CBRS
through
1/
25/
94)
submissions
in
support
of
the
reregistration
of
bentazon
have
been
reviewed.
Although
additional
data
on
storage
stability
have
been
required,
CBRS
believes
the
existing
data
base
constitutes
a
substantially
complete
data
base
2
sufficient
to
assess
dietary
exposure
and
reassess
existing
tolerances.
Magnitude
of
the
residue
data
on
bean
vines,
dried
peas,
pea
hay,
soybean
forage,
and
soybean
hay
indicate
that
the
existing
tolerances
for
residues
of
bentazon
in/
on
these
commodities
are
inadequate
to
cover
the
currently
registered
use.
Provided
that
the
registrant
proposes
appropriate
tolerance
increases
for
these
commodities,
CBRS
has
no
objection
to
the
reregistration
of
bentazon.

A
confined
rotational
crop
study
required
under
the
8/
29/
90
Bentazon
DCI
is
currently
under
review
(
D196299,
MRID
42361901).
Conclusions
regarding
the
adequacy
of
these
data
to
fulfill
GLN
165­
1
requirements
will
be
addressed
in
an
addendum
to
this
RED
Chapter.

Attachments:
Product
and
Residue
Chemistry
Chapters
for
the
Bentazon
Reregistration
Eligibility
Document
(
RED).
CBRS
No.
11440;
DP
BARCODE
D188712.

cc:
PADeschamp
(
CBRS),
Circulate,
Bentazon
RegStd
File,
SF,
Dynamac
Corporation,
Eric
Feris
(
RB/
SRRD),
Charles
Frick
and
Flora
Chow
(
CCB/
HED).
cc:
RF
(
Without
attachment)
Electronic
Media:
F:\
USER\
CB\
REDS\
Bentazon.
RED
7509C:
CBRS:
PDeschamp:
CM#
2:
Rm804A:
703­
305­
6227:
01/
26/
94
RDI:
MMetzger:
01/
31/
94
BENTAZON
REREGISTRATION
ELIGIBILITY
DOCUMENT:

PRODUCT
CHEMISTRY
CONSIDERATIONS
(
Shaughnessy
No.
103901;
Case
No.
0182)

(
CBRS
No.
11440;
DP
Barcode
D188712)

TASK
2A
DESCRIPTION
OF
CHEMICAL
Bentazon
(
3­(
1­
methylethyl)­
1H­
2,1,3­
benzothiadiazin­
4(
3H)­
one
2,2­
dioxide)
is
a
selective
herbicide
used
post­
emergence
on
broadleaf
weeds
and
sedges.
Bentazon
is
formulated
and
used
as
the
sodium
salt
alone
or
in
combination
with
atrazine.

Empirical
Formula:
C10H12N2O3S
Molecular
Weight:
240.3
CAS
Registry
No.:
50723­
80­
3
Shaughnessy
No.:
103901
bentazon
sodium
salt
(
275200
bentazon)

IDENTIFICATION
OF
ACTIVE
INGREDIENT
Technical
grade
bentazon
is
a
colorless
to
white
solid
with
a
melting
point
of
137­
139
C
and
a
vapor
pressure
of
<
1
x
10­
7
mm
Hg
at
20
C.
The
solubility
(
g/
100
g
solvent,
20
C)
of
bentazon
is
0.05
in
water,
150.7
in
acetone,
3.3
in
benzene,
18.0
in
chloroform,
86.1
in
ethanol,
61.6
in
ethyl
acetate,
0.02
in
cyclohexane,
and
2.7
in
olive
oil.
The
bentazon
sodium
salt
is
more
soluble
in
water
(
230
g/
100
g).

MANUFACTURING­
USE
PRODUCTS
A
search
of
the
Reference
Files
System
(
REFS)
conducted
7/
27/
93
identified
two
registered
bentazon
sodium
salt
manufacturing­
use
products
(
MPs),
a
60%
formulation
intermediate
(
FI;
EPA
Reg.
No.
7969­
42)
and
a
53%
FI
(
EPA
Reg.
No.
7969­
84).
Both
are
registered
to
BASF
Wyandotte
Corporation.
The
sodium
salt
FIs
are
manufactured
by
an
integrated
system.
We
note
that
REFS
identifies
EPA
Reg.
No.
7969­
42
as
a
60%
formulation,
while
the
Bentazon
Reregistration
Standard
dated
7/
26/
84
and
the
Reregistration
Standard
Update
dated
3/
19/
90
refer
to
the
product
as
a
46%
formulation.
In
addition,
REFS
identifies
EPA
Reg.
No.
7969­
84
as
a
53%
formulation,
while
the
Reregistration
Standard
Update
refers
to
the
product
as
a
53.25%
formulation.
Throughout
this
document
the
products
will
be
identified
as
2
the
46%
and
53%
FIs,
respectively.
Only
the
two
BASF
MPs
are
subject
to
a
reregistration
eligibility
decision.

REGULATORY
BACKGROUND
The
regulatory
background
for
bentazon
products
in
terms
of
comprehensive
product
chemistry
reviews
is
presented
below.
The
Bentazon
Guidance
Document
dated
9/
85
required
data
concerning
the
46%
FI
manufactured
by
the
"
original"
manufacturing
process.
Shortly
following
the
release
of
the
Guidance
Document,
BASF
submitted
data
concerning
a
different
manufacturing
process,
the
AIPAM
process.
Although
data
for
both
the
"
original"
and
AIPAM
manufacturing
processes
have
been
submitted
in
support
of
the
46%
FI,
CBRS
notes
that,
according
to
a
CSF
dated
10/
20/
86
which
lists
different
impurities
for
the
different
manufacturing
processes,
the
46%
FI
does
not
have
a
"
single,
defined
composition"
as
required
in
40
CFR
§
152.43(
a).
The
registrant
must
seek
either
registration
of
a
basic
and
alternate
formulation
for
the
46%
sodium
salt
FI
or
separate
registration
for
the
products
produced
by
the
distinct
manufacturing
processes.
The
53%
FI,
which
is
produced
exclusively
by
the
AIPAM
process,
was
not
registered
at
the
time
of
the
Reregistration
Standard,
and
therefore
was
not
addressed
in
the
Reregistration
Standard
or
the
Reregistration
Standard
Update.

September
1985
Guidance
Document
March
1990
Update
Products
Data
required
Data
submitted
in
response
Data
required
Data
submitted
in
response
Bentazon
TGAI
a
61­
2,
­
3
62­
1
63­
7,
­
10,
­
11,
­
12
61­
2,
­
3
62­
1
63­
7,
­
10,
­
11,
­
12,
­
13
61­
2,
­
3
62­
1
None
46%
FI
sodium
salt
a
61­
1,
­
2,
­
3
62­
1,
­
2,
­
3
63­
7,
­
12,
­
14,
­
16,
­
20
61­
1,
­
2,
­
3
62­
1,
­
2,
­
3
63­
16,
­
20
61­
1,
­
2,
­
3
62­
3
63­
2,
­
3,
­
4,
­
7,
­
12,
­
14,
­
15,
­
17,
­
18,
­
19
None
53%
FI
sodium
salt
none;
not
registered
until
1986
N/
A
b
N/
A
61,
62,
63
series
submitted
in
support
of
reregistration
a
Except
for
the
data
requirements
listed
for
the
Guidance
Document,
data
requirements
and
submissions
pertain
to
both
the
"
original"
and
AIPAM
manufacturing
processes.

b
N/
A
=
not
applicable
The
current
status
of
the
product
chemistry
data
requirements
for
the
BASF
bentazon
TGAI
and
bentazon
sodium
salt
products
are
presented
in
the
attached
data
summary
tables.
Please
refer
to
these
tables
for
a
listing
of
the
outstanding
product
chemistry
data
requirements.
3
CONCLUSIONS
The
registrant
must
seek
either
registration
of
a
basic
and
alternate
formulation
for
the
46%
sodium
salt
FI
or
separate
registration
for
two
products
as
produced
by
the
distinct
manufacturing
processes.
Provided
that
the
registrant
submits
the
data
required
in
the
attached
data
summary
tables
for
the
46%
FI
(
EPA
Reg.
No.
7969­
42)
and
53%
FI
(
EPA
Reg.
No.
7969­
84)
and
either
certifies
that
the
suppliers
of
starting
materials
and
the
manufacturing
processes
for
the
bentazon
sodium
salt
products
have
not
changed
since
the
last
comprehensive
product
chemistry
review
or
submits
a
complete
updated
product
chemistry
data
package,
CBRS
has
no
objections
to
the
reregistration
of
bentazon
with
respect
to
product
chemistry
data
requirements.

AGENCY
MEMORANDA
CITED
IN
THIS
DOCUMENT
CBRS
No(
s).:
491
Subject:
EPA
Registration
No.
7969­
42.
(
RCB
No.
491).
Bentazon,
Sodium
Salt.
Product
Chemistry
Data
dated
March
1985
and
July
2,
1985
for
Reregistration.
From:
N.
Dodd
To:
A.
Rispin
and
R.
Taylor
Dated:
4/
29/
86
MRID(
s):
00148848
CBRS
No(
s).:
1717
Subject:
BASF
Corporation­
Response
to
the
Product
Chemistry
Chapter­
Bentazon
Registration
Standard.
From:
G.
P.
Makhijani
To:
R.
Taylor
and
A.
Rispin
Dated:
2/
5/
87
MRID(
s):
00155470,
00157712,
00164085,
00165273,
and
00165274
CBRS
No(
s).:
2275
Subject:
BASF
Corporation­
Response
to
Bentazon
Registration
Standard.
From:
G.
P.
Makhijani
To:
R.
Taylor
and
A.
Rispin
Dated:
7/
10/
87
MRID(
s):
40051601
CBRS
No(
s).:
10123
DP
Barcode
No:
D179481
Subject:
Reregistration
of
Bentazon.
Product
Chemistry.
Generic
and
Product
Specific
Data
Requirements
From:
P.
Deschamp
To:
E.
Feris
Dated:
8/
3/
93
MRID(
s):
40549001,
40549002,
and
40549003
PRODUCT
CHEMISTRY
CITATIONS
References
(
cited):

00051878
(
1973)
Physical
and
Chemical
Properties
of
Basagran.
Unpublished
study
including
published
data,
submitted
by
BASF
Wyandotte
Corporation.
4
00064303
(
1973)
Chemical
Names,
Structures,
Properties
of
Bentazon
and
Basagran.
Reports
by
various
sources;
unpublished
study,
including
published
data,
submitted
by
BASF
Wyandotte
Corporation.

00079081
(
1973)
Basagran
®
:
Experimental
Herbicide.
Rev.
Parsippany,
N.
J.:
BASF.
Technical
data
sheet;
also
unpublished
submitted
by
BASF
Wyandotte
Corporation.

00106223
(
1972)
Chemistry
of
Bentazon.
Unpublished
study
submitted
by
BASF
Wyandotte
Chemical
Corporation.

00148848
(
1985)
Basagran
Manufacturers'
Concentrate...
Updated
Product
Chemistry
Information.
Unpublished
compilation
submitted
by
BASF
Wyandotte
Corporation.
87
p.

00155470
(
1985)
90
Day
Response
to
Registration
Notice
of
9/
27/
85
for
Sodium
Bentazon.
Unpublished
compilation
submitted
by
BASF
Wyandotte
Corporation.
67
p.

00157712
(
1986)
6
Month
Response
to
Reregistration
Notice
of
9/
27/
85
for
Sodium
Bentazon:
EPA
Case
No.
182:
Product
Chemistry.
Unpublished
compilation
submitted
by
BASF
Wyandotte
Corporation.
160
p.

00164085
Liesner,
M.
(
1986)
Method
of
Analysis
­
Two
Reports:
Product
Chemistry:
Analytical
Methods:
Bentazon
and
Basagran.
Unpublished
study
prepared
by
BASF
Analytical
Laboratory.
23
p.

00165273
(
1986)
Bentazon
Revision
of
Product
Chemistry
Response
to
PM
25
Letter
Dated
6/
16/
86:
Product
Identity
and
Composition.
Unpublished
compilation
submitted
by
BASF
Wyandotte
Corporation.
97
p.

00165274
(
1986)
Bentazon
Revision
of
Product
Chemistry
Response
to
PM
25
Letter
Dated
6/
16/
86:
Analysis
and
Certification
of
Product
Ingredients.
Unpublished
compilation
submitted
by
BASF
Wyandotte
Corporation.
58
p.

40051601
Fassler,
H.
(
1973)
Corrosion
Tests
in
Sodium
Bentazon.
Unpublished
study
prepared
by
BASF
Corp.,
Material
Engineering,
Engineering
and
Logistics
Laboratory.
14
p.

40391301
Nelsen,
T.
(
1987)
The
Determination
of
Water,
Sodium,
Chloride,
Phosphate,
Sulfate
and
Organic
Impurities
in
Technical
Bentazon
and
Bentazon­­
Sodium
550
g/
l:
Doc.
#
BASF
87/
5066.
Unpublished
study
prepared
by
BASF
Analytical
Laboratory.
44
p.

40549001
Nelsen,
T.
(
1988)
Data
Concerning
the
Product
Identity
and
Composition
of
Basagran
Manufacturers
Concentrate­­
600
g/
l:
Reg.
Doc.
#
BASF
88/
5011.
Unpublished
study
prepared
by
BASF
Agricultural
Research
Station.
12
p.

40549002
Nelsen,
T.
(
1988)
The
Analysis
and
Certification
of
Limits
of
Basagran
Manufacturers
Concentrate­­
600
g/
l:
Reg.
Doc.
#
BASF
88/
5009.
Unpublished
study
prepared
by
BASF
Agricultural
Research
Station.
16
p.

40549003
Nelsen,
T.
(
1988)
Data
Concerning
the
Physical
and
Chemical
Characteristics
of
Basagran
Manufacturers
Concentrate­­
600
g/
l:
Reg.
Doc.
#
BASF
88/
5010.
Unpublished
study
prepared
by
BASF
Agricultural
Research
Station.
27
p.
5
Case
No.
0182
Chemical
No.
103901
Case
Name:
Bentazon
Registrant:
BASF
Corporation
Product(
s):
Bentazon
TGAI
manufactured
by
the
"
original"
process
PRODUCT
CHEMISTRY
DATA
SUMMARY
Guideline
Number
Requirement
Are
Data
Requirements
Fulfilled?
a
MRID
Number
b
61­
1
Product
Identity
and
Disclosure
of
Ingredients
N/
A
c
61­
2
Starting
Materials
and
Manufacturing
Process
N
d
00157712
61­
3
Discussion
of
Formation
of
Impurities
Y
00157712
62­
1
Preliminary
Analysis
Y
00165274
62­
2
Certification
of
Ingredient
Limits
N/
A
c
62­
3
Analytical
Methods
to
Verify
the
Certified
Limits
N/
A
c
63­
2
Color
Y
00051878,
00064303,
00079081,
00106223
63­
3
Physical
State
Y
00051878,
00064303,
00079081,
00106223
63­
4
Odor
Y
00051878,
00064303,
00079081,
00106223
63­
5
Melting
Point
Y
00051878,
00064303,
00079081,
00106223
63­
6
Boiling
Point
N/
A
63­
7
Density,
Bulk
Density
or
Specific
Gravity
Y
00157712
63­
8
Solubility
Y
00051878,
00064303,
00079081,
00106223
63­
9
Vapor
Pressure
Y
00051878,
00064303,
00106223
63­
10
Dissociation
Constant
Y
00155470
63­
11
Octanol/
Water
Partition
Coefficient
Y
00157712
63­
12
pH
Y
00155470
63­
13
Stability
Y
00051878,
00064303,
00106223
a
Y
=
Yes;
N
=
No;
N/
A
=
Not
Applicable.
6
b
Bolded
references
were
reviewed
in
the
Bentazon
Reregistration
Standard
dated
7/
26/
84;
unbolded
references
were
reviewed
under
CBRS
No.
1717,
dated
2/
5/
87,
by
G.
Makhijani.

c
Data
are
not
required
for
the
TGAI.

d
These
data
do
not
fully
satisfy
the
requirements
of
40
CFR
§
158.160
and
§
158.162
(
Guideline
Reference
No.
61­
2)
regarding
the
starting
materials
and
manufacturing
process
because
the
relative
amounts
of
the
starting
materials,
the
duration
of
the
reaction
steps,
a
complete
description
of
the
physical
conditions
(
pH,
temperature,
pressure),
and
a
description
of
quality
control
procedures
are
required
to
complete
the
original
submission.
7
Case
No.
0182
Chemical
No.
103901
Case
Name:
Bentazon
Registrant:
BASF
Corporation
Product(
s):
Bentazon
TGAI
manufactured
by
the
AIPAM
process
PRODUCT
CHEMISTRY
DATA
SUMMARY
Guideline
Number
Requirement
Are
Data
Requirements
Fulfilled?
a
MRID
Number
b
61­
1
Product
Identity
and
Disclosure
of
Ingredients
N/
A
c
61­
2
Starting
Materials
and
Manufacturing
Process
N
d
00157712
61­
3
Discussion
of
Formation
of
Impurities
Y
00157712
62­
1
Preliminary
Analysis
Y
00165274
62­
2
Certification
of
Ingredient
Limits
N/
A
c
62­
3
Analytical
Methods
to
Verify
the
Certified
Limits
N/
A
c
63­
2
Color
N
63­
3
Physical
State
N
63­
4
Odor
N
63­
5
Melting
Point
N
63­
6
Boiling
Point
N/
A
63­
7
Density,
Bulk
Density
or
Specific
Gravity
Y
40549003
63­
8
Solubility
N
63­
9
Vapor
Pressure
Y
00051878,
00064303,
00106223
63­
10
Dissociation
Constant
Y
00155470
63­
11
Octanol/
Water
Partition
Coefficient
Y
00157712
63­
12
pH
N
63­
13
Stability
N
a
Y
=
Yes;
N
=
No;
N/
A
=
Not
Applicable.

b
Bolded
references
were
reviewed
in
the
Bentazon
Reregistration
Standard
dated
7/
26/
84;
unbolded
references
were
reviewed
under
CBRS
No.
1717,
dated
2/
5/
87,
by
G.
Makhijani;
underlined
references
were
reviewed
under
CBRS
No.
10123,
dated
8/
3/
93,
by
P.
Deschamp.

c
Data
are
not
required
for
the
TGAI.

d
These
data
do
not
fully
satisfy
the
requirements
of
40
CFR
§
158.160
and
§
158.162
(
Guideline
Reference
No.
61­
2)
regarding
the
starting
materials
and
manufacturing
process
because
the
relative
amounts
of
the
starting
materials,
the
duration
of
the
reaction
steps,
and
a
description
of
quality
control
procedures
are
required
to
complete
the
original
submission.
8
Case
No.
0182
Chemical
No.
103901
Case
Name:
Bentazon
Registrant:
BASF
Corporation
Product(
s):
53%
sodium
salt
FI
(
EPA
Reg.
No.
7969­
84);
produced
exclusively
by
the
AIPAM
process.

PRODUCT
CHEMISTRY
DATA
SUMMARY
Guideline
Number
Requirement
Are
Data
Requirements
Fulfilled?
a
MRID
Number
b
61­
1
Product
Identity
and
Disclosure
of
Ingredients
Y
40549001,
40549002
61­
2
Starting
Materials
and
Manufacturing
Process
N
c
40549001
61­
3
Discussion
of
Formation
of
Impurities
N
d
40549001
62­
1
Preliminary
Analysis
Y
40549002
62­
2
Certification
of
Ingredient
Limits
N
e
40549002
62­
3
Analytical
Methods
to
Verify
the
Certified
Limits
N
f
40549002
63­
2
Color
N
g
40549003
63­
3
Physical
State
N
g
40549003
63­
4
Odor
N
g
40549003
63­
5
Melting
Point
N
h
63­
6
Boiling
Point
N/
A
63­
7
Density,
Bulk
Density
or
Specific
Gravity
Y
40549003
63­
8
Solubility
N
h
63­
9
Vapor
Pressure
Y
00051878,
00064303,
00106223
63­
10
Dissociation
Constant
Y
00155470
63­
11
Octanol/
Water
Partition
Coefficient
Y
00157712
63­
12
pH
N
i
63­
13
Stability
N
h
63­
14
Oxidizing
or
Reducing
Action
N
j
63­
15
Flammability
N
j
63­
16
Explodability
Y
40549003
63­
17
Storage
Stability
Y
40549003
63­
18
Viscosity
Y
40549003
63­
19
Miscibility
N
j
40549003
63­
20
Corrosion
Characteristics
N
j
a
Y
=
Yes;
N
=
No;
N/
A
=
Not
Applicable.

b
Bolded
references
were
reviewed
in
the
Bentazon
Reregistration
Standard
dated
7/
26/
84;
unbolded
references
were
reviewed
under
CBRS
No.
1717,
dated
2/
5/
87,
by
G.
Makhijani;
underlined
references
were
reviewed
under
CBRS
No.
10123,
dated
8/
3/
93,
by
P.
Deschamp.

c
These
data
do
not
fully
satisfy
the
requirements
of
40
CFR
§
158.160­
165
(
Guideline
Reference
No.
61­
2)
regarding
the
starting
materials
and
manufacturing
process
because
the
registrant
must
submit:
(
i)
relative
amounts
of
starting
materials;
(
ii)
the
duration
of
the
reaction
steps
for
the
manufacturing
process;
and
(
iii)
descriptions
of
procedures
used
to
assure
consistent
composition
(
quality
control)
of
the
final
product.
9
d
These
data
do
not
fully
satisfy
the
requirements
of
40
CFR
§
158.167
(
Guideline
Reference
No.
61­
3)
regarding
discussion
of
the
formation
of
impurities
because
a
discussion
of
post­
production
contamination
and
degradation
of
materials
must
be
submitted.

e
These
data
do
not
fully
satisfy
the
requirements
of
40
CFR
§
158.175
(
Guideline
Reference
No.
62­
2)
regarding
certified
limits
because
a
revised
CSF,
with
the
correct
EPA
Reg.
No.,
must
be
submitted
on
EPA
Form
8570­
4
(
Rev.
12­
90).

f
These
data
do
not
fully
satisfy
the
requirements
of
40
CFR
§
158.180
(
Guideline
Reference
No.
62­
3)
regarding
enforcement
analytical
methods
because
validation
data
for
the
method
used
to
determine
bentazon
per
se
must
be
submitted.
The
following
additional
information
must
also
be
submitted:
(
i)
a
statement
of
the
precision
of
the
method
pertaining
to
impurity
1.1.2;
(
ii)
validation
data
for
the
remainder
of
the
impurities;
and
(
iii)
a
method
for
determination
of
a
solvent
used
in
the
manufacturing
process.

g
Data
requirements
are
satisfied
for
the
MP;
however,
data
are
required
for
the
bentazon
TGAI
manufactured
by
the
AIPAM
process.

h
Data
are
required
for
the
bentazon
TGAI
manufactured
by
the
AIPAM
process.

i
Data
are
required
for
the
bentazon
TGAI
manufactured
by
the
AIPAM
process
and
for
the
MP.

j
Data
are
required
for
the
specific
MP.
10
Case
No.
0182
Chemical
No.
103901
Case
Name:
Bentazon
Registrant:
BASF
Corporation
Product(
s):
46%
sodium
salt
FI
(
EPA
Reg.
No.
7969­
42);
produced
by
both
the
"
original"
and
AIPAM
processes.

PRODUCT
CHEMISTRY
DATA
SUMMARY
Guideline
Number
Requirement
Are
Data
Requirements
Fulfilled?
a
MRID
Number
b
61­
1
Product
Identity
and
Disclosure
of
Ingredients
N
c
00148848,
00165273
61­
2
Starting
Materials
and
Manufacturing
Process
N
d
00148848,
00165273
61­
3
Discussion
of
Formation
of
Impurities
N
e
00148848,
00165273
62­
1
Preliminary
Analysis
Y
00148848,
00165274
f
62­
2
Certification
of
Ingredient
Limits
N
g
00148848,
00165273
62­
3
Analytical
Methods
to
Verify
the
Certified
Limits
N
h
00148848,
00164085,
00165274
f,
40391301
i
63­
2
Color
N
j
63­
3
Physical
State
N
j
63­
4
Odor
N
j
63­
5
Melting
Point
N
k
63­
6
Boiling
Point
N/
A
63­
7
Density,
Bulk
Density
or
Specific
Gravity
N
l
63­
8
Solubility
N
k
63­
9
Vapor
Pressure
Y
00051878,
00064303,
00106223
63­
10
Dissociation
Constant
Y
00155470
f
63­
11
Octanol/
Water
Partition
Coefficient
Y
00157712
f
63­
12
pH
N
j
63­
13
Stability
N
k
63­
14
Oxidizing
or
Reducing
Action
N
l
63­
15
Flammability
N
l
63­
16
Explodability
Y
00157712
f
63­
17
Storage
Stability
N
63­
18
Viscosity
N
l
63­
19
Miscibility
N
l
63­
20
Corrosion
Characteristics
N
m
40051601
n
a
Y
=
Yes;
N
=
No;
N/
A
=
Not
Applicable.

b
Bolded
references
were
reviewed
in
the
Bentazon
Reregistration
Standard
dated
7/
26/
84;
italicized
references
were
originally
reviewed
under
CBRS
No.
1717,
dated
2/
5/
87,
by
G.
Makhijani
and
were
re­
evaluated
in
the
Bentazon
Update
dated
3/
9/
90;
underlined
references
were
reviewed
under
CBRS
No.
491,
dated
4/
29/
86,
by
N.
Dodd;
all
other
references
are
reviewed
as
noted.

c
These
data
do
not
fully
satisfy
the
requirements
of
40
CFR
§
158.155
(
Guideline
Reference
No.
61­
1)
regarding
product
identity
because
nominal
concentrations
must
be
reported
for
ingredients
present
at
11
concentrations
 
0.1%,
and
an
impurity
identified
at
a
concentration
 
0.1%
during
preliminary
analysis
of
the
product
manufactured
by
the
"
original"
process
must
be
added
to
the
CSF.

d
These
data
do
not
fully
satisfy
the
requirements
of
40
CFR
§
158.160­
165
(
Guideline
Reference
No.
61­
2)
regarding
the
starting
materials
and
manufacturing
process
for
both
manufacturing
processes,
because
the
registrant
must
submit:
(
i)
relative
amounts
of
starting
materials;
(
ii)
the
duration
of
the
reaction
steps
for
the
manufacturing
process;
and
(
iii)
descriptions
of
procedures
used
to
assure
consistent
composition
(
quality
control)
of
the
final
product.
Furthermore,
a
complete
description
of
the
physical
conditions
(
pH,
temperature,
pressure,
etc.)
influencing
the
manufacture
of
the
FI
by
the
"
original"
process
must
be
submitted.
We
also
note
that
the
CSF
dated
10/
20/
86
lists
impurities
present
in
the
product
formed
by
the
"
original"
process
as
well
as
those
formed
by
the
"
AIPAM"
process;
thus,
this
product
does
not
have
a
"
single,
defined
composition"
as
required
in
40
CFR
§
152.43(
a).
The
registrant
must
seek
either
registration
of
a
basic
and
alternate
formulation
for
the
46%
sodium
salt
FI
or
separate
registration
for
two
products
as
produced
by
the
distinct
manufacturing
processes.

e
These
data
do
not
fully
satisfy
the
requirements
of
40
CFR
§
158.167
(
Guideline
Reference
No.
61­
3)
regarding
discussion
of
the
formation
of
impurities
because
a
discussion
of
post­
production
contamination
and
degradation
of
materials
in
the
product
as
produced
by
both
manufacturing
processes
must
be
submitted.

f
CBRS
No.
1717,
dated
2/
5/
87,
by
G.
Makhijani.

g
These
data
do
not
fully
satisfy
the
requirements
of
40
CFR
§
158.175
(
Guideline
Reference
No.
62­
2)
regarding
certified
limits
because
new
CSFs
reflecting
basic
and
alternate
formulations
or
two
separate
registrations
must
be
submitted
for
the
product
as
produced
by
the
different
manufacturing
processes.

h
These
data
do
not
fully
satisfy
the
requirements
of
40
CFR
§
158.180
(
Guideline
Reference
No.
62­
3)
regarding
enforcement
analytical
methods
because
validation
data
for
the
method
used
to
determine
the
active
ingredient,
bentazon,
must
be
submitted.
The
following
additional
information
must
also
be
submitted
for
the
product
as
manufactured
by
the
AIPAM
process:
(
i)
a
statement
of
the
precision
of
the
method
pertaining
to
the
impurity
1.1.2;
(
ii)
validation
data
for
the
remainder
of
the
impurities;
and
(
iii)
a
method
for
determination
of
a
solvent
used
in
the
AIPAM
manufacturing
process.

i
Bentazon
Reregistration
Standard
Update
dated
3/
9/
90.

j
Data
are
required
for
the
bentazon
TGAI
manufactured
by
the
AIPAM
process
and
the
specific
MP.

k
Data
are
required
for
the
bentazon
TGAI
manufactured
by
the
AIPAM
process.

l
Data
are
required
for
the
specific
MP.

m
Data
are
required
on
the
MP
manufactured
by
the
"
original"
process.

n
CBRS
No.
2275,
dated
7/
10/
87,
by
G.
Makhijani.
BENTAZON
REREGISTRATION
ELIGIBILITY
DOCUMENT
RESIDUE
CHEMISTRY
CONSIDERATIONS
Shaughnessy
No.
103901;
Case
0182
(
CBRS
No.
11440;
DP
Barcode
D188712)

TASK
2B
Table
of
Contents
Page
INTRODUCTION................................................................................................................................................
1
REGULATORY
BACKGROUND........................................................................................................................
1
SUMMARY
OF
SCIENCE
FINDINGS...............................................................................................................
2
GLN
171­
3:
Directions
for
Use...............................................................................................................
2
GLN
171­
4
(
a):
Plant
Metabolism
..........................................................................................................
2
GLN
171­
4
(
b):
Animal
Metabolism
......................................................................................................
2
GLN
171­
4
(
c)
and
(
d):
Residue
Analytical
Methods
­
Plants
and
Animals.........................................
3
GLN
171­
4
(
e):
Storage
Stability
............................................................................................................
3
GLN
171­
4
(
k):
Magnitude
of
the
Residue
in
Plants
.............................................................................
4
GLN
171­
4
(
l):
Magnitude
of
the
Residue
in
Processed
Food/
Feed.....................................................
4
GLN
171­
4
(
j):
Magnitude
of
the
Residue
in
Meat,
Milk,
Poultry
and
Eggs
........................................
4
GLNs
165­
1
and
165­
2:
Confined/
Field
Rotational
Crops....................................................................
4
Table
A.
Registered
uses
of
bentazon
for
BASF
Corporation.........................................................
5
Table
B.
Residue
chemistry
science
assessments
for
reregistration
of
bentazon
........................
10
TOLERANCE
REASSESSMENT
SUMMARY...................................................................................................
16
Tolerances
Listed
Under
40
CFR
§
180.355(
a)
......................................................................................
16
Tolerances
Listed
Under
40
CFR
§
180.355(
b)
......................................................................................
16
Tolerances
Listed
Under
40
CFR
§
186.375
...........................................................................................
16
Table
C.
Tolerance
Reassessment
Summary..................................................................................
17
CODEX
HARMONIZATION
.............................................................................................................................
18
AGENCY
MEMORANDA
CITED
IN
THIS
DOCUMENT.................................................................................
19
BENTAZON
REREGISTRATION
ELIGIBILITY
DOCUMENT
RESIDUE
CHEMISTRY
CONSIDERATIONS
Shaughnessy
No.
103901;
Case
0182
INTRODUCTION
Bentazon
[
3­
isopropyl­
1H­
2,1,3­
benzothiadiazin­
4(
3H)­
one­
2,2­
dioxide,
sodium
salt]
is
an
herbicide
registered
for
selective
postemergence
control
of
weeds
in
variety
of
food
and
feed
crops;
refer
to
Table
A
for
a
comprehensive
list
of
use
sites.
Bentazon
is
typically
applied
as
a
postemergence
broadcast
spray
to
target
weeds.
[
Source:
LUIS
General
Chemical
Report
for
Bentazon,
2/
3/
93).

REGULATORY
BACKGROUND
Tolerances
for
residues
of
bentazon
in/
on
raw
and
processed
agricultural
food/
feed
commodities
are
currently
expressed
in
terms
of
the
combined
residues
of
bentazon
and
its
6­
and
8­
hydroxy
metabolites
[
Source:
40
CFR
§
180.355(
a)
and
40
CFR
§
186.375].
These
tolerances
are
set
at
0.05­
4
ppm.
[
NOTE:
Tolerances
for
residues
of
bentazon
in/
on
dried
beans,
sweet
corn,
corn
grain,
peanuts,
chili
peppers,
rice
grain,
sorghum
grain,
sorghum
fodder,
and
soybeans
are
established
at
0.05
ppm,
the
individual
detection
limits
for
bentazon
and
its
6­
and
8­
hydroxy
metabolites.]
Tolerances
for
food
items
derived
from
animals
are
expressed
in
terms
of
the
combined
residues
of
bentazon
and
AIBA
[
Source:
40
CFR
§
180.355(
b)].
The
chemical
structures
of
bentazon
and
its
metabolites
of
concern
are
presented
in
Figure
A.
Adequate
enforcement
methods
are
available
for
the
determination
of
these
regulated
compounds
in/
on
plant
and
animal
commodities.

Figure
A.
Chemical
structures
of
bentazon
metabolites
presently
included
in
the
tolerance
expressions.

6­
hydroxy
bentazon:
6­
hydroxy­
3­
isopropyl­
1H­
2,1,3­
benzothiadizi
n­
4­(
3H­
)
one­
2,2­
dioxide
8­
hydroxy
bentazon:
8­
hydroxy­
3­
isopropyl­
1H­
2,1,3­
benzothiadizin­
4­(
3H­)
one­
2,2­
dioxide
AIBA:
2­
amino­
Nisopropyl
benzamide
The
Reregistration
Standard
Guidance
Document
for
bentazon
was
issued
9/
85.
The
Bentazon
Residue
Chemistry
Reregistration
Standard
Update
was
completed
on
3/
19/
90.
The
information
contained
in
this
document
outlines
the
Residue
Chemistry
Science
Assessments
with
respect
to
the
reregistration
of
bentazon.

SUMMARY
OF
SCIENCE
FINDINGS
GLN
171­
3:
Directions
for
Use:
A
REFS
search
conducted
7/
27/
93
indicated
that
there
are
seven
end­
use
bentazon
products
registered
to
BASF
Corporation
for
use
on
food/
feed
crops
as
follows:

4.0
lb/
gal
SC/
L
(
EPA
Reg.
No.
7969­
45,
1/
29/
93
and
SLNs
NC810023
and
WA900012)
3.3
lb/
gal
SC/
L
(
EPA
Reg.
No.
7969­
78,
1/
15/
90)
3.0
lb/
gal
SC/
L
(
EPA
Reg.
No.
7969­
77,
6/
24/
93)
2.66
lb/
gal
SC/
L
(
EPA
Reg.
Nos.
7969­
82,
4/
19/
93
and
7969­
83,
dated
1/
29/
93)
2.67
lb/
gal
SC/
L
(
EPA
Reg.
No.
7969­
76,
5/
18/
93)
1.66
lb/
gal
FlC
(
EPA
Reg.
No.
7969­
54,
1/
29/
93)
2.5
lb/
gal
FlC
(
EPA
Reg.
No.
7969­
100,
6/
23/
93)

A
comprehensive
summary
of
the
registered
use
patterns
of
bentazon,
based
on
these
product
labels,
is
presented
in
Table
A.
The
conclusions
regarding
the
reregistration
eligibility
of
bentazon
on
the
crops
listed
in
Table
A
are
based
on
the
use
patterns
registered
by
the
basic
producer,
BASF
Corporation.
When
end­
use
product
DCIs
are
developed
(
e.
g.
at
issuance
of
the
RED),
RD
should
require
that
all
end­
use
product
labels
(
e.
g.
MAI
labels,
SLNs,
and
products
subject
to
the
generic
data
exemption)
be
amended
such
that
they
are
consistent
with
the
basic
producer
labels.

Label
amendments
to
specify
a
40­
day
PHI
must
be
proposed
for
all
products
registered
for
use
on
peas.

GLN
171­
4
(
a):
Plant
Metabolism:
The
qualitative
nature
of
the
residue
in
plants
is
adequately
understood.
Studies
with
a
variety
of
plants
including
beans
(
dry
and
succulent),
corn,
soybeans
(
seeds,
forage,
and
hay),
rice
(
grain
and
straw),
and
wheat
indicate
that
bentazon
is
readily
absorbed
from
foliage,
roots,
and
seeds.
Translocation
throughout
rice
and
wheat
plants
is
extensive;
limited
translocation
in
navy
beans
and
soybeans
occurs.
Bentazon
is
rapidly
metabolized,
conjugated,
and
incorporated
into
natural
plant
constituents.
Metabolism
involves
the
hydroxylation
of
bentazon
at
the
6­
and
8­
position
and
subsequent
conjugation
with
carbohydrates
or
fragmentation
and
incorporation
into
natural
constituents
such
as
lignin,
proteins,
and
polysaccharide
fractions
(
starch,
pectin,
hemicellulose,
and
cellulose).
The
terminal
residues
of
concern
are
bentazon,
6­
hydroxy
bentazon,
and
8­
hydroxy
bentazon.

GLN
171­
4
(
b):
Animal
Metabolism:
The
qualitative
nature
of
the
residue
in
animals
is
adequately
understood.
Studies
involving
dairy
cows
dosed
with
[
U­
14C]
bentazon,
[
14C]
8­
hydroxy
bentazon,
and
[
14C]
6­
hydroxy
bentazon
at
1
ppm
(
0.5x),
5
ppm
(
2.5x),
and
20
ppm
(
10x)
in
the
diet
for
a
maximum
of
28
days
demonstrated
that
bentazon
is
absorbed
and
rapidly
eliminated
in
the
urine
after
oral
dosing.
Bentazon
and
2­
amino­
N­
isopropyl
benzamide
(
AIBA)
accounted
for
the
majority
of
the
terminal
residues
in
tissues
and
milk.
Studies
involving
laying
hens
dosed
with
[
U­
14C]
bentazon
at
100
ppm
(
2000x)
in
the
diet
for
5
days
demonstrated
that
limited
accumulation
and
metabolism
occurs;
>
80%
of
the
TRR
in
tissues
and
eggs
was
identified
as
unchanged
bentazon;
16%
of
the
TRR
in
liver
consisted
of
N­
glucuronide
conjugate
of
bentazon.
Dosing
at
this
highly
exaggerated
rate
yielded
the
highest
total
radioactivity
(
1.632
ppm)
in
liver.
The
presence
of
detectable
residues
of
bentazon
in
poultry
tissues
and
eggs
from
a
1x
feeding
level
is
unlikely.
The
terminal
residues
to
be
regulated
in
animal
tissues,
eggs,
and
milk
consist
of
bentazon
and
its
metabolite
AIBA.
The
current
tolerances
and
tolerance
expression
adequately
cover
these
residues
in
animal
commodities.
3
GLN
171­
4
(
c)
and
(
d):
Residue
Analytical
Methods
­
Plants
and
Animals:
Adequate
enforcement
methods
are
available
for
the
determination
of
residues
of
bentazon
and
its
6­
and
8­
hydroxy
metabolites
in/
on
plant
commodities
and
for
the
determination
of
bentazon
and
AIBA
in
animal
commodities.
The
Pesticide
Analytical
Manual
(
PAM)
Vol.
II
lists
Method
II,
a
GLC
method
with
flame
photometric
detection
for
the
determination
of
bentazon
and
its
hydroxy
metabolites
in/
on
corn,
rice,
and
soybeans;
the
limit
of
detection
for
each
compound
is
0.05
ppm.
Method
I,
a
GLC
method
with
nitrogen­
specific
Coulson
conductivity
detection,
is
available
for
the
determination
of
residues
of
bentazon
and
AIBA
in
animal
tissues,
eggs,
and
milk;
the
limit
of
detection
for
each
compound
is
0.05
ppm
in
tissues
and
eggs
and
0.02
ppm
in
milk.
Method
III,
modified
from
Method
II,
is
available
for
the
determination
of
bentazon
and
its
hydroxy
metabolites
in/
on
peanuts
and
seed
and
pod
vegetables
with
a
limit
of
detection
of
0.05
ppm
for
each
compound.

Radiolabeled
validation
of
the
current
tolerance
enforcement
method
(
PAM
Vol.
II,
Section
180.355,
Method
II)
by
analysis
of
methanol
soluble
fractions
of
soybean
forage
samples
from
the
soybean
metabolism
study
indicates
that
methanol­
soluble
residues
of
bentazon
and
its
hydroxy
metabolites
are
adequately
recovered
by
this
method.

Residue
data
submitted
in
response
to
the
Guidance
Document
and
in
support
of
petitions
for
the
establishment
of
new
tolerances
were
collected
using
modifications
of
the
available
PAM
Vol.
II
methods.
CBRS
has
concluded
that
these
modified
methods,
along
with
the
methods
listed
in
PAM
Vol.
II,
are
adequate
for
bentazon
data
collection
and
tolerance
enforcement.

The
FDA
PESTDATA
database
dated
August
1993
(
PAM
Vol.
I,
Appendix
II)
does
not
contain
data
concerning
the
applicability
of
FDA
multiresidue
methods
for
recovery
of
bentazon,
and
its
hydroxymetabolites
Data
depicting
the
recovery
of
bentazon,
6­
hydroxy
bentazon,
and
8­
hydroxy
bentazon,
through
the
multiresidue
methods
remain
outstanding.

GLN
171­
4
(
e):
Storage
Stability:
Storage
stability
studies
have
been
conducted
using
samples
of
rice
grain,
rice
straw,
snapbean
vines,
snapbean
cannery
waste,
soybeans,
soybean
forage,
corn
forage,
peanut
forage,
flax
seed,
flax
straw
and
flax
meal.
These
data
indicate
that
residues
of
bentazon,
8­
OH­
bentazon,
and
6­
OH­
bentazon
are
relatively
stable
in
these
matrices
for
up
to
two
years
of
frozen
storage
(­
5
to
­
27
±
C).
Thus,
by
translation,
representative
storage
stability
data
are
available
for
samples
of
oil
seeds,
non­
oily
grains,
legume
vegetables
(
dried
and
succulent),
and
low
moisture
content
forages/
hays
stored
under
conditions
and
intervals
of
those
samples
from
residue
field
trials
used
to
reassess
existing
tolerances.
Additional
storage
stability
data
are
needed
to
validate
processing
studies
(
corn,
peanuts,
rice,
and
soybeans)
for
which
data
are
either
lacking
or
incomplete.
Storage
stability
data
for
processed
items
reflecting
up
to
14
months
of
frozen
storage
are
needed
to
support
these
processing
studies.
These
data
are
considered
confirmatory
to
the
existing
evidence
that
residues
of
bentazon,
6­
OH­
bentazon,
and
8­
OHbentazon
are
relatively
stable
in
unprocessed
frozen
plant
matrices.

No
storage
stability
data
for
animal
commodities
are
available;
these
data
are
outstanding
and
are
considered
confirmatory.
Data
are
required
reflecting
the
storage
stability
of
bentazon
and
AIBA
in
cattle
and
poultry
tissues,
milk,
and
eggs.
Storage
intervals
and
conditions
must
reflect
the
existing
cattle
metabolism/
feeding
study
(
MRID
00039849),
the
existing
poultry
metabolism/
feeding
study
(
MRID
00039856),
and
the
existing
poultry
metabolism
study
(
MRID
41089101).
Because
available
storage
stability
data
for
plant
commodities
indicate
that
residues
are
generally
stable,
CBRS
considers
the
available
information
sufficient
to
support
the
cattle
and
poultry
metabolism/
feeding
studies.
The
additional
data
are
required
to
confirm
the
conclusions
that
the
existing
animal
commodity
tolerances
are
adequate.

GLN
171­
4
(
k):
Magnitude
of
the
Residue
in
Plants:
All
data
submitted
in
response
to
reregistration
requirements
pertaining
to
the
magnitude
of
the
residue
in
plants
have
been
evaluated
and
deemed
adequate.
Field
trials
were
typically
conducted
according
to
the
parameters
of
registered
use
patterns.
The
geographical
representation
for
each
commodity
is
generally
adequate
and
a
sufficient
number
of
trials
reflecting
representative
formulation
classes
were
conducted.
The
existing
3
ppm
tolerances
for
residues
of
4
bentazon
in/
on
bean
forage,
pea
vine
hay,
soybean
forage,
and
soybean
hay
are
inadequate
to
cover
the
currently
registered
use;
tolerances
of
10
ppm
for
"
beans,
vines",
8
ppm
for
pea
vine
hay,
8
ppm
for
soybean
forage,
and
8
ppm
for
soybean
hay
would
be
adequate
to
cover
the
expected
residues
resulting
from
the
currently
registered
use
pattern.
The
existing
0.05
ppm
for
dried
peas
is
inadequate
to
cover
the
currently
registered
use;
a
tolerance
of
1
ppm
would
be
adequate
to
cover
the
expected
residues
resulting
from
the
currently
registered
use
pattern.

GLN
171­
4
(
l):
Magnitude
of
the
Residue
in
Processed
Food/
Feed:
Processing
studies
have
been
conducted
on
the
following
RACs:
field
corn,
peanuts,
rice
grain,
mint,
soybeans,
and
snapbeans
(
forage/
cannery
waste).
Data
on
the
potential
for
residue
concentration
in
grain
sorghum
processed
products
have
not
been
required.
All
data
submitted
in
response
to
reregistration
requirements
for
magnitude
of
the
residue
in
processed
food/
feed
have
been
evaluated
and
deemed
adequate,
pending
submission
of
acceptable
storage
stability
data
on
processed
food/
feed
items.
Residue
concentration
was
observed
in
snapbean
cannery
waste,
spent
mint
hay,
and
rice
hulls.
A
4
ppm
feed
additive
tolerance
for
residues
in
spent
mint
hay
has
been
established;
a
feed
additive
tolerance
of
0.25
ppm
must
be
proposed
for
residues
of
bentazon
in
rice
hulls.

GLN
171­
4
(
j):
Magnitude
of
the
Residue
in
Meat,
Milk,
Poultry
and
Eggs:
The
ruminant
metabolism
studies
in
which
lactating
dairy
cows
received
[
U­
14C]
bentazon
at
1
ppm
(
0.25x),
5
ppm
(
2.5x),
and
20
ppm
(
10x)
in
the
diet
for
a
maximum
of
28
days
provide
data
to
reassess
the
adequacy
of
the
existing
0.02
ppm
tolerance
for
the
combined
residues
of
bentazon
and
AIBA
in
milk
and
the
0.05
ppm
tolerances
for
the
combined
residues
of
bentazon
and
AIBA
in
fat,
meat
byproducts
and
meat
of
cattle,
goats,
hogs,
and
sheep.
The
poultry
metabolism
studies
in
which
laying
hens
received
[
U­
14C]
bentazon
at
100
ppm
(
2000x)
in
the
diet
for
5
days
provide
data
to
reassess
the
adequacy
of
the
existing
0.05
ppm
tolerances
for
the
combined
residues
of
bentazon
and
AIBA
in
eggs
and
the
fat,
meat
byproducts
and
meat
of
poultry.
The
storage
stability
data
to
support
these
studies
are
outstanding.
Because
existing
data
provide
preliminary
evidence
of
stability
of
the
residues,
CBRS
considers
the
available
information
adequate
to
conclude
that
the
established
tolerances
on
livestock
commodities
are
appropriate.

GLNs
165­
1
and
165­
2:
Confined/
Field
Rotational
Crops:
Data
pertaining
to
confined
rotational
crop
studies
are
currently
under
review
by
CBRS
(
D196299;
MRID
42963701)
and
will
be
presented
as
an
addendum
to
this
RED
Chapter.
(
continued;
footnotes
follow)

Table
A.
Registered
uses
of
bentazon
for
BASF
Corporation.
1
Crop
Formulation
Maximum
Single
Application
Rate
(
lb
ai/
A)
Maximum
Seasonal
Rate
(
lb
ai/
A)
PHI/
PGI
2
(
Days)
Use
Limitation
Alfalfa
(
seed
crop)
3
4
lb/
gal
SC/
L
1.0
Use
limited
to
WA
(
WA900012)
for
broadcast
postemergence
application
using
ground
or
aerial
equipment
with
an
oil
concentrate.
The
use
of
any
portion
of
the
treated
field,
including
forage,
hay,
seed,
or
seed
screenings
for
human
or
animal
feed
is
prohibited.

The
use
of
treated
alfalfa
for
sprouting
is
prohibited.
No
PHI
or
maximum
seasonal
rate
has
been
established.

Beans
(
dry
and
succulent)
4
lb/
gal
SC/
L
1.5
2.0
30
PHI
Broadcast
postemergence
application
limited
to
IL,
IN,

KY,
MI,
and
OH
using
ground
or
aerial
equipment.

4
lb/
gal
SC/
L
1.0
2.0
30
PHI
Broadcast
postemergence
application
using
ground
or
aerial
equipment.
A
second
application
may
be
made
at
a
7­
to
14­
day
interval.

Corn
(
field,
pop,
seed
crop,

and
sweet)
4
lb/
gal
SC/
L
1.5
2.0
12
PGI
Broadcast
postemergence
application
using
ground
or
aerial
equipment.

4
lb/
gal
SC/
L
0.75
0.75
21
PGI
A
single
broadcast
postemergence
tank
mix
use
with
atrazine.

Corn
(
field)
1.66
lb/
gal
FlC
2.5
lb/
gal
FlC
0.73
0.73
21
PGI
A
single
broadcast
postemergence
application
using
ground
or
aerial
equipment.
Application
may
be
made
alone
or
as
tank
mix
with
other
pesticides.
Use
in
CA
is
prohibited.

Corn
(
pop,
seed
crop,
and
sweet)
1.66
lb/
gal
FlC
2.5
lb/
gal
FlC
0.73
0.73
21
PGI
A
single
broadcast
postemergence
application
using
ground
or
aerial
equipment.
Use
in
CA
is
prohibited.

Peanuts
4
lb/
gal
SC/
L
1.5
2.0
50
PGI
Broadcast
postemergence
application
using
ground
or
(
continued;
footnotes
follow)

Crop
Formulation
Maximum
Single
Application
Rate
(
lb
ai/
A)
Maximum
Seasonal
Rate
(
lb
ai/
A)
PHI/
PGI
2
(
Days)
Use
Limitation
aerial
equipment.
Application
may
be
made
alone
or
as
a
tank
mix
with
other
herbicides.

2.67
lb/
gal
SC/
L
0.5
1.0
75
PHI
Broadcast
postemergence
application
using
ground
or
aerial
equipment.
Use
of
treated
plants
for
feed
or
forage
is
prohibited.
Application
may
be
made
alone
or
as
a
tank
mix
with
other
herbicides.

Peas
(
dried
and
succulent)
4
lb/
gal
SC/
L
1.0
2.0
30
PHI
Broadcast
postemergence
application
using
ground
or
aerial
equipment.
Application
may
be
made
alone
or
as
a
tank
mix
with
other
herbicides.

Peppermint
4
lb/
gal
SC/
L
2.0
4.0
Broadcast
postemergence
application
using
ground
or
aerial
equipment.
A
second
application
may
be
made
at
a
5­
to
14­
day
interval.
No
PHI
has
been
established.

Peppers,
chili,

Bohemian
4
lb/
gal
SC/
L
1.0
2.0
Use
limited
to
NC
(
NC810023)
for
a
broadcast
postemergence
application
using
ground
equipment.
A
second
application
may
be
made
at
a
7­
to
10­
day
interval.
No
PHI
has
been
established.

Rice
4
lb/
gal
SC/
L
1.0
3.0
(
2.0
lb
ai/
A
in
first
crop
and
1.0
lb
ai/
A
in
second
ratoon
crop)
Broadcast
postemergence
application
using
ground
or
aerial
equipment.
The
following
are
prohibited:
(
i)
use
of
ground
equipment
for
applications
of
flooded
fields;
(
ii)

use
on
rice
fields
in
which
the
commercial
cultivation
of
catfish
or
crayfish
is
practiced;
and
(
iii)
use
in
CA.

Application
may
be
made
alone
or
as
a
tank
mix
with
other
herbicides.
No
PHI
has
been
established.

Rice
(
continued)
3.3
lb/
gal
SC/
L
1.0
3.0
(
2.0
lb
ai/
A
in
first
crop
and
1.0
lb
ai/
A
in
second
ratoon
crop)
Broadcast
postemergence
application
using
ground
or
aerial
equipment.
The
following
are
prohibited:
(
i)
use
of
ground
equipment
for
applications
of
flooded
fields;
and
(
ii)
use
on
rice
fields
in
which
the
commercial
cultivation
of
catfish
or
crayfish
is
practiced.
Rice
straw
may
be
fed
to
livestock
up
to
7
days
before
slaughter.
No
PHI
has
(
continued;
footnotes
follow)

Crop
Formulation
Maximum
Single
Application
Rate
(
lb
ai/
A)
Maximum
Seasonal
Rate
(
lb
ai/
A)
PHI/
PGI
2
(
Days)
Use
Limitation
been
established.

Sorghum
4
lb/
gal
SC/
L
1.0
1.0
12
PGI
A
single
broadcast
postemergence
application
using
ground
or
aerial
equipment.
Application
to
sorghum
that
is
heading
or
blooming
is
prohibited.
Application
may
be
made
alone
or
as
tank
mix
with
other
pesticides.

1.66
lb/
gal
FlC
2.5
lb/
gal
FlC
0.73
0.73
21
PGI
A
single
broadcast
postemergence
application
using
ground
or
aerial
equipment.
Application
to
sorghum
that
is
heading
or
blooming
is
prohibited.
Use
in
CA
is
prohibited.

Soybeans
4
lb/
gal
SC/
L
1.5
2.0
30
PHI
30
PGI
Broadcast
postemergence
application
using
ground
or
aerial
equipment.
Application
may
be
made
alone
or
as
tank
mix
with
other
pesticides.

3.0
lb/
gal
SC/
L
0.75
1.1
50
PHI
Broadcast
postemergence
application
using
ground
or
aerial
equipment.
Application
may
be
made
alone
or
as
tank
mix
with
other
pesticides.
Use
of
treated
plants
for
feed
or
forage
is
prohibited.

2.67
lb/
gal
SC/
L
0.5
1.0
50
PHI
Broadcast
postemergence
application
using
ground
or
aerial
equipment.
Use
of
treated
plants
for
feed
or
forage
is
prohibited.
Application
may
be
made
alone
or
as
a
tank
mix
with
other
herbicides.

Soybeans
(
continued)
2.66
lb/
gal
SC/
L
0.75
0.75
Use
limited
to
DE,
IL,
IN,
KS,
KY,
MA,
MD,
ME,
MI,
MN,

MO,
NE,
NH,
NJ,
NY,
OH,
PA,
RI,
VA,
WI,
and
WV
for
a
single
broadcast
postemergence
application
using
ground
or
aerial
equipment.
Grazing
of
treated
areas
or
harvesting
for
forage
or
hay
is
prohibited.
Grazing
of
rotated
small
grain
crops
or
harvesting
for
livestock
forage
or
straw
is
prohibited.
Maximum
number
of
applications
to
any
field
is
one
every
two
years.
(
continued;
footnotes
follow)

Crop
Formulation
Maximum
Single
Application
Rate
(
lb
ai/
A)
Maximum
Seasonal
Rate
(
lb
ai/
A)
PHI/
PGI
2
(
Days)
Use
Limitation
2.66
lb/
gal
SC/
L
0.5
0.5
Use
limited
to
AL,
AR,
DE,
GA,
IA,
IL,
IN,
KS,
KY,
LA,

MA,
ME,
MD,
MI,
MN,
MO,
MS,
NC,
NE,
NH,
NJ,
NY,

OH,
OK,
PA,
RI,
SC,
TN,
TX,
VA,
VT,
WV,
and
WI
for
a
single
broadcast
postemergence
application
using
ground
or
aerial
equipment.
Grazing
of
treated
areas
or
harvesting
for
forage
or
hay
is
prohibited.
Grazing
of
rotated
small
grain
crops
or
harvesting
for
livestock
forage
or
straw
is
prohibited.
Maximum
number
of
applications
to
any
field
in
DE,
IA,
IL,
IN,
KS,
KY,
MA,

ME,
MD,
MI,
MN,
MO,
NE,
NH,
NJ,
NY,
OH,
PA,
RI,
VA,

VT,
WI
and
WV
is
one
every
two
years.

Spearmint
4
lb/
gal
SC/
L
2.0
4.0
see
"
Peppermint."

1.
These
use
directions
were
obtained
from
the
following
bentazon
end­
use
product
labels
registered
to
BASF
Corporation:
(
i)
4
lb/
gal
SC/
L
(
EPA
Reg.
No.
7969­
45,
dated
1/
29/
93
and
SLNs
NC810023
and
WA810023);
(
ii)
3.3
lb/
gal
SC/
L
(
EPA
Reg.
No.
7969­
78,
dated
1/
15/
90);
(
iii)
3.0
lb/
gal
SC/
L
(
EPA
Reg.
No.
7969­
77,
dated
6/
24/
93);
(
iv)
2.66
lb/
gal
SC/
L
(
EPA
Reg.
Nos.
7969­
82,
dated
4/
19/
93
and
7969­
83,
dated
1/
29/
93);

(
v)
2.67
lb/
gal
SC/
L
(
EPA
Reg.
No.
7969­
76,
dated
5/
18/
93);
(
vi)
1.66
lb/
gal
FlC
(
EPA
Reg.
No.
7969­
54,
dated
1/
29/
93);
and
(
vii)
2.5
lb/
gal
FlC
(
EPA
Reg.
No.
7969­
100,
dated
6/
23/
93).

2.
PHI
=
Preharvest
interval;
PGI
=
Pregrazing
interval.

3.
Alfalfa
grown
for
seed
will
be
regulated
as
a
non­
food
use
provided
the
restrictions
and
limitations
stated
above
are
enforced
(
letter
dated
2/
4/
88
from
J.
Akerman
to
M.
Toohey
in
conjunction
with
WA810023).
(
continued;
footnotes
follow)
9
Table
B.
Residue
chemistry
science
assessments
for
reregistration
of
bentazon.

Data
Requirements
Tolerances,
ppm
[
40
CFR]
Must
Additional
Data
Be
Submitted?
Referencesi
GLN
171­
3:
Directions
for
Use
Yesii
N/
A
GLN
171­
4
(
a):
Plant
Metabolism
No
00039278,
00039279,
00039280,
00039281,
00039282,
00039283,
00039284,
00039285,
00039656,
00039657,
00039659,
00039660,
00039661,
00039664,
00039665,
00039666,
00039667,
00039668,
00039669,
00039670,
00039671,
00039672,
00039852,
00040184,
00040188,
00040516,
00040517,
00040518,
00040519,
00051652,
00051653,
00051654,
00051655,
00051656,
00052050,
00052052,
00052055,
00084714,
00084715,
00106221,
00106230,
00108281,
40432801,
40432802,
41658101,
iii
41779501,
iv
417795034
GLN
171­
4
(
b):
Animal
Metabolism
No
00039848,
00039849,
00039850,
00039851,
00039853,
00039854,
00039855,
00039856,
00039857,
00039860,
00039861,
00039862,
00040110,
00040111,
00044781,
00044782,
00051652,
00063615,
00137904,
41089101,
41658101,3
41730101,4
417795024
GLN
171­
4
(
c/
d):
Residue
Analytical
Methods
Yesv
00023509,
00039658,
00039851,
00040185,
00040186,
00040187,
00040517,
00040521,
00040522,
00040785,
00044782,
00051657,
00106263,
40051602
GLN
171­
4
(
e):
Storage
Stability
Yesvi
00039290,
00040189,
(
continued;
footnotes
follow)
10
Data
Requirements
Tolerances,
ppm
[
40
CFR]
Must
Additional
Data
Be
Submitted?
Referencesi
00040193,
42587004­
42587009vii
GLN
171­
4
(
k):
Magnitude
of
the
Residue
in
Plants
Legume
Vegetables
Group
­
Beans,
dry
0.05
[
§
180.355(
a)]
No
00023507,
00040520,
00106243,
00106263
­
Beans,
succulent
(
except
lima)
0.5
[
§
180.355(
a)]
No
00023507,
00026208,
00106243,
00106263,
41123101viii
­
Beans,
lima
0.05
[
§
180.355(
a)]
No
00023507,
00040520,
00051911,
00106231,
00106263
­
Peas,
dried
0.05
[
§
180.355(
a)]
Yesix
00051912,
41101702x
­
Peas,
succulent
0.5
[
§
180.355(
a)]
No
00023507,
00040520,
00040521,
00051912,
00106243,
00106263
­
Soybeans
0.05
[
§
180.355(
a)]
Noxi
00023507,
00031796,
00040172,
00040173,
00040174,
00040176,
00040177,
00040178,
00040179,
00040180,
00040181,
00040182,
00040183,
00040184,
00040186,
00051658,
00079082,
00106228,
00106263,
4110170110
Foliage
of
Legume
Vegetables
­
Beans,
vines
and
hay
3
(
forage)
3
(
dry
vine
hay)
[
§
180.355(
a)]
Yesxii
00040521,
00051911,
00051912,
00106231,
00106236,
00106243,
41123101?

­
Peas,
vines
and
hay
3
(
forage)
3
(
dry
vine
hay)
[
§
180.355(
a)]
Yesxiii
00051912,
00106243,
4110170210
­
Soybeans,
forage
and
hay
3
(
forage)
0.3
(
hay)
[
§
180.355(
a)]
Yesxiv
00031796,
00040176,
00040183,
00051658,
00079082,
00106227,
00106228,
00106236,
4110170110
Fruiting
Vegetables
Group
­
Peppers,
chili,
Bohemian
0.05
[
§
180.355(
a)]
No
00106245
Cereal
Grains
Group
(
continued;
footnotes
follow)
11
Data
Requirements
Tolerances,
ppm
[
40
CFR]
Must
Additional
Data
Be
Submitted?
Referencesi
­
Corn,
field,
grain
0.05
[
§
180.355(
a)]
No
00023507,
00023508,
00023511,
00106251,
00106252,
00106254,
00106263,
00108303
­
Corn,
pop,
grain
0.05
[
§
180.355(
a)]
Noxv
­
Corn,
sweet
(
K
+
CWHR)
0.05
[
§
180.355(
a)]
No
00023511,
00040171,
00106238,
00106253
­
Rice,
grain
0.05
[
§
180.355(
a)]
No
00040819,
00040820,
00040821,
00040822,
00040823,
00040824,
00040825,
00040828,
00040829,
00040830,
00040831,
00040832,
00040833,
00040834,
00052053,
00084711,
00106238
­
Sorghum,
grain
0.05
[
§
180.355(
a)]
No
00126689
Forage,
Fodder,
and
Straw
of
Cereal
Grains
Group
­
Corn,
field,
forage
and
fodder
3
(
forage)
3
(
fodder)
[
§
180.355(
a)]
No
00023511,
00040171,
00106238,
00106251,
00106252,
00106253,
00106254,
00106263,
00108303
­
Corn,
pop,
forage
and
fodder
3
(
forage)
3
(
fodder)
[
§
180.355(
a)]
Noxvi
­
Corn,
sweet,
forage
3
(
forage)
[
§
180.355(
a)]
No
00106238
­
Rice,
straw
3
[
§
180.355(
a)]
No
00040820,
00040821,
00040822,
00040823,
00040825,
00040827,
00040829,
00040831,
00040832,
00040833,
00040834,
00052053,
00106238
­
Sorghum,
forage
and
fodder
0.20
(
forage)
0.05
(
fodder)
[
§
180.355(
a)]
No
00126689
Miscellaneous
Commodities
­
Peanuts
0.05
(
nutmeat)
3
(
vines)
3
(
hay)
0.3
(
hulls)
No
00023507,
00023511,
00106237,
00106263
(
continued;
footnotes
follow)
12
Data
Requirements
Tolerances,
ppm
[
40
CFR]
Must
Additional
Data
Be
Submitted?
Referencesi
[
§
180.355(
a)]

­
Mint
1
[
§
180.355(
a)]
No
00023507,
00023511,
00106241,
00106263
GLN
171­
4(
l):
Magnitude
of
the
Residue
in
Processed
Food/
Feed
­
Beans,
succulent
and
dried
No
411231018
­
Corn,
field
No
00023511,
00108303,
425870017
­
Mint
4
(
spent
hay)
[
§
186.375]
No
00023507,
00023511,
00106241,
00106263
­
Peanuts
No
00023511,
00106237
­
Rice,
grain
No
00040824,
00052053,
425870037
­
Sorghum,
grain
Noxvii
­
Soybeans
No
00040177,
00051658,
425870027
GLN
171­
4
(
j):
Magnitude
of
the
Residue
in
Meat,
Milk,
Poultry,
and
Eggs
­
Fat,
meat,
and
meat
byproducts
of
cattle,
goats,
hogs,
and
sheep
0.05
[
§
180.355(
b)]
No
00039849
­
Milk
0.02
[
§
180.355(
b)]
No
00039849
­
Eggs,
and
the
fat,
meat,
and
meat
byproducts
of
poultry
0.05
[
§
180.355(
b)]
No
00039855,
00039856
GLN
165­
1:
Rotational
Crops
(
Confined)
Yesxviii
GLN
165­
2:
Rotational
Crops
(
Field)
Yes18
Table
B
(
continued).

13
Table
B
(
continued).

14
15
TOLERANCE
REASSESSMENT
SUMMARY
Tolerances
Listed
Under
40
CFR
§
180.355(
a):

The
tolerances
listed
in
40
CFR
§
180.355(
a)
are
for
the
combined
residues
of
bentazon
and
its
6­
and
8­
hydroxy
metabolites.

Sufficient
data
are
available
to
ascertain
the
adequacy
of
the
established
tolerances
listed
in
40
CFR
§
180.355(
a)
for
the
following
commodities:
beans,
dried;
beans,
succulent;
beans,
hay;
corn,
field
and
pop,
grain;
corn,
field,
pop,
and
sweet,
forage;
corn,
field
and
pop,
fodder;
corn,
sweet
(
K+
CWHR);
mint;
peanuts;
peanuts,
hay;
peanuts,
hulls;
peanuts,
vines;
peas,
succulent;
peas,
vines;
peppers,
chili,
Bohemian;
rice,
grain;
rice,
straw;
sorghum,
fodder;
sorghum,
forage;
and
sorghum,
grain;
see
Table
C
for
modifications
in
commodity
definitions.

The
available
residue
data
indicate
that
the
established
tolerances
for
bean
vines,
dried
peas,
pea
hay,
soybean
forage,
and
soybean
hay
are
too
low.
Tolerance
revisions
must
be
proposed
as
follows:
(
i)
from
3
ppm
to
10
ppm
for
bean
vines;
(
ii)
from
0.05
ppm
to
1
ppm
for
dried
peas;
(
iii)
from
3
ppm
to
8
ppm
for
pea
hay
and
soybean
forage;
and
(
iv)
from
0.3
ppm
to
8
ppm
for
soybean
hay.
Tolerance
revisions
have
been
proposed
(
PP#
9F3782)
for
dry
beans
and
dried
peas
(
from
0.05
ppm
to
1
ppm),
bean
hay,
bean
vines,
pea
hay,
pea
vines,
soybean
forage
(
from
3
ppm
to
8
ppm),
and
soybean
hay
(
from
0.3
ppm
to
8
ppm).

The
established
tolerance
for
succulent
lima
beans
should
be
revoked
since
residues
in/
on
lima
beans
are
covered
under
the
tolerance
for
succulent
beans.

The
tolerance
for
Bohemian
chili
peppers
is
listed
incorrectly
as
0.5
ppm
in
40
CFR
§
180.355(
a).
The
entry
should
be
revised
to
reflect
the
correct
tolerance
of
0.05
ppm.

Bentazon
is
registered
for
alfalfa
grown
for
seed.
No
tolerances
are
required
for
alfalfa
grown
for
seed
since
label
restrictions
prohibit
the
use
of
treated
plant
for
sprouting
and
the
use
any
portion
of
the
treated
field
including
forage,
hay,
seed,
or
seed
screenings
for
human
or
animal
feed.

Tolerances
Listed
Under
40
CFR
§
180.355(
b):

The
tolerances
listed
in
40
CFR
§
180.355(
b)
are
for
food
items
derived
from
animals
and
are
expressed
in
terms
of
the
combined
residues
of
bentazon
and
AIBA.

Sufficient
data
are
available
to
ascertain
the
adequacy
of
the
established
tolerances
listed
in
40
CFR
§
180.355(
b)
for
milk
and
eggs
and
the
fat,
meat
byproducts,
and
meat
of
cattle,
goat,
hogs,
poultry,
and
sheep.

Tolerances
Listed
Under
40
CFR
§
186.375:

The
tolerance
listed
in
40
CFR
§
186.375
is
for
the
combined
residues
of
bentazon
and
its
6­
and
8­
hydroxy
metabolites.
Sufficient
data
are
available
to
ascertain
the
adequacy
of
the
established
feed
additive
tolerance
listed
in
40
CFR
§
186.375
for
mint,
hay,
spent;
see
Table
C
for
the
modification
in
the
commodity
definition.

A
feed
additive
tolerance
must
be
proposed
for
the
combined
residues
of
bentazon
and
its
6­
and
8­
hydroxy
metabolites
in
rice
hulls.
(
continued)
16
Table
C.
Tolerance
Reassessment
Summary.

Commodity
Current
Tolerance
(
ppm)
Tolerance
Reassessment
(
ppm)
Comment/
Correct
Commodity
Definition
Tolerances
listed
under
40
CFR
§
180.355(
a)

Beans
(
except
soybeans),
dried
0.05
0.05
Beans,
dry
Beans
(
exc.
soybeans),
dried,
vine
hays
3
3
Beans,
hay
Beans
(
exc.
soybeans),
forage
3
10
Established
tolerance
is
too
low/
Beans,
vines
Beans,
lima
(
succulent)
0.05
Revoke
Covered
under
tolerance
for
beans,
succulent
Beans,
succulent
0.5
0.5
Bohemian
chili
peppers
0.5
0.05
Tolerance
is
listed
incorrectly
in
40
CFR/
Peppers,
chili,
Bohemian
Corn,
fodder
3
3
Corn,
field,
fodder
and
Corn,
pop,
fodder
Corn,
forage
3
3
Corn,
field,
forage;
Corn,
pop,
forage;
and
Corn,
sweet,
forage
Corn,
grain
0.05
0.05
Corn,
field,
grain;
and
Corn,
pop,
grain
Corn,
fresh
(
inc.
sweet
K+
CWHR)
0.05
0.05
Corn,
sweet
(
K
+
CWHR)

Mint
1
1
Peanuts
0.05
0.05
Peanuts,
hay
3
3
Peanuts,
hulls
0.3
0.3
Peanuts,
forage
3
3
Peanuts,
vines
Peas
(
dried)
0.05
1
Established
tolerance
is
too
low/
Peas,
dried
Peas
(
dried),
vine
hays
3
8
Established
tolerance
is
too
low/
Peas,
hay
Peas,
forage
3
3
Peas,
vines
Peas,
succulent
0.5
0.5
Rice
0.05
0.05
Rice,
grain
Rice,
straw
3
3
Sorghum,
fodder
0.05
0.05
Sorghum,
forage
0.20
0.20
Sorghum,
grain
0.05
0.05
Soybeans
0.05
0.05
Soybeans,
forage
3
8
Soybeans,
hay
0.3
8
(
continued)
17
Commodity
Current
Tolerance
(
ppm)
Tolerance
Reassessment
(
ppm)
Comment/
Correct
Commodity
Definition
Tolerances
listed
under
40
CFR
§
180.355(
b)

Cattle,
fat
0.05
0.05
Cattle,
mbyp
0.05
0.05
Cattle,
meat
0.05
0.05
Eggs
0.05
0.05
Goats,
fat
0.05
0.05
Goats,
mbyp
0.05
0.05
Goats,
meat
0.05
0.05
Hogs,
fat
0.05
0.05
Hogs,
mbyp
0.05
0.05
Hogs,
meat
0.05
0.05
Milk
0.02
0.02
Poultry,
fat
0.05
0.05
Poultry,
mbyp
0.05
0.05
Poultry,
meat
0.05
0.05
Sheep,
fat
0.05
0.05
Sheep,
mbyp
0.05
0.05
Sheep,
meat
0.05
0.05
Tolerances
listed
under
40
CFR
§
186.375
Spent
mint
hay
4
4
Mint,
hay,
spent
Tolerances
to
be
proposed
Rice,
hulls
N/
A
0.25
CODEX
HARMONIZATION
No
Codex
MRLs
for
bentazon
have
been
established.
However,
there
are
bentazon
Codex
proposals
for
several
crops
at
Step
3
of
the
Codex
procedure.
The
Codex
definitions
of
the
residue
for
plants
and
animals
are
the
same
as
current
U.
S.
definitions.
For
most
of
the
proposed
limits,
there
is
compatibility
with
current
U.
S.
tolerances.
However,
the
proposed
Codex
MRL
and
U.
S
tolerance
levels
are
incompatible
for
succulent
beans
and
garden
peas
(
Codex,
0.2
ppm;
U.
S.,
0.5
ppm),
milk
(
Codex,
0.05
ppm,
the
limit
of
detection;
U.
S.,
0.02
ppm),
and
rice
(
Codex,
0.1
ppm;
U.
S.,
0.05
ppm).
If
these
proposed
Codex
levels
reach
the
CXL
step,
compatibility
with
U.
S.
tolerances
may
be
achieved
by
increasing
the
U.
S
tolerances
for
milk
and
rice
grain
to
0.05
and
0.1
ppm,
respectively,
toxicological
considerations
permitting,
and
by
reducing
the
established
U.
S.
tolerances
for
succulent
beans
and
peas
from
0.5
ppm
to
0.2
ppm;
the
available
residue
data
would
support
these
tolerance
reductions.
18
AGENCY
MEMORANDA
CITED
IN
THIS
DOCUMENT
CBTS
Nos.:
5840
and
5841
Subject:
PP#
9F3782:
Reg.
No.
7969­
45.
Bentazon
(
Basagran)
Herbicide.
Review
of
Analytical
Method
and
Residue
Data.
Request
for
Higher
Tolerances
for
Certain
Raw
Agricultural
Commodities.
From:
S.
Malak
To:
R.
Taylor/
V.
Walters
and
Toxicology
Branch
Dated:
9/
14/
90
MRID(
s):
41101701,
41101702,
and
41123101.

CBRS
No.:
7254
Subject:
BASF
Corporation:
Response
to
the
Bentazon
Reregistration
Standard:
Metabolism
Information.
From:
R.
Perfetti
To:
R.
Engler
and
L.
Rossi
Dated:
3/
21/
91
MRID(
s):
41658101.

CBRS
No.:
7904
Subject:
Reregistration
of
Bentazon.
Magnitude
of
the
Residue
in
Dry
Peas
and
Soybeans.
DP
Barcode
No.:
D163697
From:
P.
Deschamp
To:
L.
Rossi
and
E.
Ferris
Dated:
2/
4/
92
MRID(
s):
41101701
and
41101702.

CBRS
No.:
8822
Subject:
Reregistration
of
Bentazon.
Snap
Bean
Forage
and
Cannery
Waste.
DP
Barcode
No.:
D170503
From:
E.
Zager
To:
L.
Rossi/
E.
Ferris
Dated:
5/
15/
92
MRID(
s):
41123101.

CBRS
Nos.:
7682
and
7820
Subject:
Reregistration
of
Bentazon.
Case
No.
0182.
Chemical
No.
103901.
Soybean
and
Rice
Plant
Metabolism.
Poultry
Metabolism.
DP
Barcode
Nos.:
D160645
and
D162587
From:
P.
Deschamp
To:
L.
Rossi/
A.
Ertman
Dated:
9/
25/
92
MRID(
s):
41730101,
41779501,
41779502,
41779503.

CBRS
No.:
11157
Subject:
Reregistration
of
Bentazon.
Case
No.
00182.
Chemical
No.
103901.
Storage
Stability
Data.
Field
Corn
Grain,
Rice
Grain,
and
Soybean
Processed
Commodities.
From:
P.
Deschamp
To:
L.
Rossi/
A.
Ertman
Dated:
11/
24/
93
MRID(
s):
42587001­
42587009
i.
Bolded
references
were
reviewed
in
the
Update
dated
3/
19/
90.
Unbolded
references
were
reviewed
in
the
Residue
Chemistry
19
Science
Chapter
of
the
Reregistration
Standard
dated
7/
26/
84.
Otherwise,
references
were
reviewed
as
noted.

ii.
Label
amendments
to
specify
a
40­
day
PHI
must
be
proposed
for
all
products
registered
for
use
on
peas.

iii.
CBRS
No.
7254,
3/
21/
91,
R.
Perfetti.

iv.
CBRS
Nos.
7682
and
7820,
DP
Barcodes
D160645
and
D162587,
9/
25/
92,
P.
Deschamp.

v.
The
FDA
PESTDATA
database
dated
August
1993
(
PAM
Vol.
I,
Appendix
II)
does
not
contain
data
concerning
the
applicability
of
FDA
multiresidue
methods
for
recovery
of
bentazon,
and
its
hydroxy­
metabolites.
Data
depicting
the
recovery
of
bentazon,
6­
hydroxy­
bentazon,
and
8­
hydroxybentazon
through
multiresidue
methods
remain
outstanding.

vi.
Storage
stability
data
for
the
processed
commodities
of
corn,
peanuts,
rice,
and
soybeans,
reflecting
up
to
14
months
of
frozen
storage,
must
be
submitted.
These
data
are
considered
confirmatory
to
the
existing
evidence
that
residues
of
bentazon,
6­
OH­
bentazon,
and
8­
OH­
bentazon
are
relatively
stable
in
frozen
plant
matrices.
Data
are
also
required
reflecting
the
storage
stability
of
bentazon
and
AIBA
in
cattle
and
poultry
tissues,
milk,
and
eggs.
Storage
intervals
and
conditions
must
reflect
the
existing
cattle
metabolism/
feeding
study
(
MRID
00039849),
the
existing
poultry
metabolism/
feeding
study
(
MRID
00039856),
and
the
existing
poultry
metabolism
study
(
MRID
41089101).
Because
available
storage
stability
data
for
plant
commodities
indicate
that
residues
are
generally
stable,
CBRS
considers
the
available
information
sufficient
to
support
the
cattle
and
poultry
metabolism/
feeding
studies.
The
additional
data
are
required
to
confirm
the
conclusions
that
the
existing
animal
commodity
tolerances
are
adequate.

vii.
CBRS
No.
11157,
DP
Barcode
D186292,
11/
24/
93,
P.
Deschamp.

viii.
CBRS
No.
8822,
DP
Barcode
D170503,
5/
15/
92,
E.
Zager.

ix.
Crop
field
trials
for
dried
peas
indicate
that
the
current
0.05
ppm
tolerance
for
residues
in/
on
dried
peas
is
too
low.
The
registrant
must
propose
a
new
tolerance
of
1
ppm
for
the
combined
residues
of
bentazon,
6­
0H,
and
8­
OH
bentazon
in/
on
"
peas,
dried"
along
with
label
amendments
specifying
a
40­
day
PHI
(
Reference
10).

x.
CBRS
No.
7904,
DP
Barcode
D163697,
2/
4/
92,
P.
Deschamp.

xi.
CBRS
has
reconsidered
the
recommendation
(
D163697,
2/
4/
92)
that
the
established
0.05
ppm
20
tolerance
for
soybeans
be
revised
to
reflect
the
combined
validated
limits
of
detection
of
bentazon
and
the
two
regulated
metabolites
and
no
longer
requests
this
tolerance
proposal.

xii.
Crop
field
trials
for
bean
vines
(
forage)
indicate
that
the
current
3
ppm
tolerance
for
residues
in/
on
bean
vines
(
forage)
is
too
low.
The
registrant
must
propose
a
new
tolerance
of
8
ppm
for
the
combined
residues
of
bentazon,
6­
0H,
and
8­
OH
bentazon
in/
on
"
beans,
vines"
(
Reference
6).

xiii.
Crop
field
trials
for
dried
pea
vine
hay
indicate
that
the
current
3
ppm
tolerance
for
residues
in/
on
dried
pea
vine
hay
is
too
low.
The
registrant
must
propose
a
new
tolerance
of
8
ppm
for
the
combined
residues
of
bentazon,
6­
0H,
and
8­
OH
bentazon
in/
on
peas,
hay
along
with
label
amendments
specifying
a
40­
day
PHI
(
Reference
10).

xiv.
Residue
data
from
soybean
forage
and
soybean
hay
field
trials
indicate
that
the
established
tolerances
for
these
commodities
(
3
and
0.3
ppm,
respectively)
are
too
low;
the
registrant
must
propose
new
tolerances
of
8
ppm
each
in/
on
soybean
forage
and
soybean
hay
(
Reference
10).

xv.
Data
submitted
for
field
corn
grain
satisfy
data
requirements
for
popcorn
grain.

xvi.
Data
submitted
for
field
corn
forage
and
fodder
satisfy
data
requirements
for
popcorn
forage
and
fodder.

xvii.
Data
on
the
potential
for
residue
concentration
in
grain
sorghum
processed
products
have
not
been
required.

xviii.
Data
pertaining
to
this
topic
are
currently
under
review
at
CBRS
(
D196299,
MRID
42361901).
Conclusions
regarding
the
need
for
additional
data
will
be
presented
in
an
addendum
to
this
RED
Chapter.
