Page
1
of
2
Triethylene
Glycol
(
083501)
Case
3145
Ecological
Hazard
Assessment
and
Environmental
Risk
Characterization
Ecological
effects
data
requirements
were
waived
for
triethylene
glycol
during
the
Phase
IV
review
(
8/
20/
92)
due
to
its
intended
use
as
an
indoor
microbiocide,
high
volatility,
and
known
low
toxicity
(
it
is
a
preferred
solvent
for
aquatic
organism
toxicity
tests).
Data
obtained
from
published
studies
provide
additional
confirmation
of
the
low
toxicity
of
the
compound
to
fish
and
aquatic
invertebrates:

Species
%
ai
Test
Type
Toxicity
Reference
Mysid
(
Mysidopsis
bahia)
99.9
96­
hour
static
acute
LC50
=
11,000
ppm
MRID
#
402284­
01
(
Mayer,
1986)

Sheepshead
minnow
(
Cyprinodon
variegatus)
99.9
96­
hour
static
acute
LC50
=
48,000
ppm
MRID
#
402284­
01
(
Mayer,
1986)

Bluegill
sunfish
(
Lepomis
macrochirus)
unknown
96
hour
static
acute
LC50
>
10,000
ppm
Verschuren,
1983
Menidia
beryllina
unknown
96
hour
static
LC50
>
10,000
ppm
Verschuren,
1983
Fathead
minnow
(
Pimephales
promelas)
unknown
96
hour
flowthrough
LC
50
59,900
­
77,400
ppm
Geiger
et
al.,
1988
A
hydrolysis
study
is
the
only
environmental
fate
data
required
for
chemicals
with
an
indoor
use
pattern.
This
data
was
waived
for
triethylene
glycol
during
Phase
IV
review.

Environmental
modeling
was
not
performed
for
triethylene
glycol.
Its
use
as
an
indoor
aerosol
microbiocide
would
be
unlikely
to
result
in
any
significant
outdoor
environmental
exposure.

Due
to
the
low
likelihood
of
environmental
exposure
and
the
demonstrated
low
toxicity
of
triethylene
glycol,
the
ecological
risk
from
the
use
of
this
chemical
as
an
indoor
aerosol
microbiocide
is
presumed
to
be
low.
Page
2
of
2
References
40228401
Mayer,
F.
L.
1986.
Acute
Toxicity
Handbook
of
Chemicals
to
Estuarine
Organisms.
Prepared
by
U.
S.
EPA
Office
of
Reserach
and
Development,
Environmental
Research
Laboratory,
Gulf
Breeze,
FLA
EPA/
600/
X­
36/
231.

Geiger,
D.
L.,
Call,
D.
J.,
and
Brooke,
L.
T.
(
Eds).
1988.
Acute
Toxicities
of
Organic
Chemicals
to
Fathead
Minnows
(
Pimephales
promelas).
Vol.
IV.
Superior
Wisconsin:
University
of
Wisconsin­
Superior.
131.

Verschuren,
K.
1983.
Handbook
of
Environmental
Data
of
Organic
Chemicals.
2nd
ed.
New
York,
NY:
Van
Nostrand
Reinhold
Co.
1153.
