Preliminary
N­
Methyl
Carbamate
Cumulative
Risk
Assessment:

Backpocket
Slides
Preliminary
N­
Methyl
Carbamate
Cumulative
Risk
Assessment:

Backpocket
Slides
FIFRA
Scientific
Advisory
Panel
August
23­
26,
2005
FIFRA
Scientific
Advisory
Panel
August
23­
26,
2005
"
Intermediate"
Water
Scenario

1­
2
year
old
child
consumes
water
over
a
16
hour
period
°
5
different
points
in
time

Each
separated
by
exactly
4
hours

Each
consisting
of
exactly
equal
amounts
of
water

Water
consumed
contains
a
concentration
drawn
from
distribution
of
water
concentrations
in
area
of
interest
0
.05
.1
Density
0
10
20
30
40
50
Water
Consumption
divided
by
5,
ml/
kg
0
.05
.1
Density
0
10
20
30
40
50
Water
Consumption
divided
by
5,
ml/
kg
0
.05
.1
Density
0
10
20
30
40
50
Water
Consumption
divided
by
5,
ml/
kg
0
1
0
2
0
3
0
4
0
De
n
sity
0
.05
.1
.15
Ground
W
ater
Concentration,
mg/
L,
Oxamyl­
equivalents
Florida
Central
Ridge
Area
Ground
Water
Concentration,
mg/
L
X
Aggregate
Exposure
Models
NHGPUS
Diaries
(
Partially
Independent
wrt
Daily
Probabilities)

Co­
occurrence
(
Conditional
Probability)
Matrix
(
Tables
II.
E.
1­
13b,
II.
E.
1­
14b)

Four
sequential
(
pair­
wise)

Links
(
Table
II.
E.
1­
12)

Co­
occurrent
Use/
Exposure
Across
Scenarios
Scenario/
Group
Average/
b
(
Avg#
Apps,
Avg
Days
Between
Apps)

(
Table
II.
E.
1­
9)

Apply
to
2nd
and
subsequent
Applications
(
Fixed
Intervals)

(
Table
II.
E.
1­
7)

Number
of
Applications
&

Interval
(
Days)
Between
Applications
Apply
to
All
Applications
(
Table
II.
E.
1­
11)

Apply
distribution
(
CDF)
to
1st
Application
(
Table
II.
E.
1­
6)

Month
or
Julian
Date
(
Day/
Week
of
Year)
All
Application
Events
Randomly
determined
based
on
NHGPUS
(#
Apps/
Yr)
&

Region.
Independent
daily
Probabilities
for
North
(=#
apps/
182.5)
and
South
(=#
apps/
365)

Distribution
All
Apps
(
Table
II.
E.
1­
10)

Distribution
1st
App
(
Table
II.
E.
1­
5)

Day
of
Week
(
Sun­
Sat)
Types
Defined
by
NHGPUS
Diaries
Single
Type
for
Each
Product­
Scenario
(
may
have
multiple
`
products')/
a
Defined
by
Number
of
Applications
&
Application
Schedules
User
Type
Option
Available
Option
Available
Option
Available
Professional
&
Homeowner
Applicators
Target
Pest
Use
Factors
via
NHGPUS
diaries
(
Table
II.
E.
1­
15)

Apply
to
all
uses
within
Scenario
(
Tables
II.
E.
1­
4,

II.
E.
1­
8)

Apply
to
Scenario
(
Table
II.
E.
1­
4)

Pct
of
Households
(
Scenario)
85
Scenarios
Affect
PHT,
potential
area
treated
(
AHS/
NGS)
&

duration
(
NHAPS)

17
Scenarios
(+
1
Custom)

Affect
PHT,
available
algorithms,
and
possibly
cooccurrence
All
Scenarios
are
`
Custom'

Scenario
Selection
Lifeline
CARES
Calendex
Residential
Use
Input
/
a
CARES
also
has
a
`
Grouping'
option.
/
b
Days
between
applications
are
indirectly
related
to
existing
applications.

Residential
Use
Inputs
