Reader's
Guide
PYRETHRINS
CRM:
Cathryn
O'Connell
EPA/
OPPTS/
OPP/
SRRD
Page
1
of
6
Reader's
Guide
to
the
Pyrethrins
Reregistration
Eligibility
Decision
(
RED)
E­
Docket
#
OPP­
2005­
0043
Publication
Date:
July
26,
2006
EPA
has
created
this
document
to
provide
an
organizational
structure
to
the
Pyrethrins
E­
docket.
The
docket
index
lists
the
caption
entries
sequentially,
while
this
document
lists
them
by
subject
matter.
The
Agency
is
providing
the
"
Readers
Guide"
to
allow
the
reader
to
more
easily
access
and
navigate
the
various
entries
contained
in
the
Pyrethrins
E­
docket.

Phase
3
Federal
Register
and
Docket
Organizational
Documents:

Docket
Entry
1.
Federal
Register
Notice:
Pyrethrins
Risk
Assessments;
Notice
of
Availability.

Docket
Entry
2.
Reader's
Guide
to
the
Pyrethrins
E­
Docket
#
OPP­
2005­
0043.
(
Version
May
5,
2005)

Docket
Entry
3.
Overview
of
the
Pyrethrins
Risk
Assessments
(
April
27,
2005)

Phase
3
Human
Health
Risk
Assessments
Documents:

Docket
Entry
4.
Pyrethrins:
Response
to
Error­
Only
Comments
to
the
HED
Risk
Assessment
and
Supporting
Documents
(
April
22,
2005)

Docket
Entry
5.
Pyrethrins:
Occupational
and
Residential
Exposure
Assessment
and
Recommendations
for
the
RED
for
Pyrethrins
(
April
21,
2005)

Docket
Entry
6.
Review
of
Pyrethrins
(
PBO)
Incident
Reports.
(
April
6,
2005)

Docket
Entry
7.
Pyrethrins:
Reregistration
Eligibility
Decision.
Product
Chemistry
Considerations.
(
March
21,
2005)

Docket
Entry
8.
Pyrethrins:
Residue
Chemistry
Considerations
for
RED
(
October
12,
2004)
Reader's
Guide
PYRETHRINS
CRM:
Cathryn
O'Connell
EPA/
OPPTS/
OPP/
SRRD
Page
2
of
6
Docket
Entry
9.
Pyrethrins:
Acute
and
Chronic
Dietary
Exposure
Assessment
for
the
RED.
(
December
20,
2004)

Docket
Entry
10.
Pyrethrins:
Report
of
the
Cancer
Assessment
Review
Committee.
Third
Evaluation.
(
June
22,
2004)

Phase
3
Ecological
Risk
Assessment
Documents:

Docket
Entry
11.
Response
to
Error
Corrections
on
the
Drinking
Waters
memorandums
and
the
Draft
EFED
RED
Chapter
for
Pyrethrins.
(
March
24,
2005)

Docket
Entry
12.
Revised
EFED
Science
Chapter
for
the
Reregistration
Eligibility
Decision
(
RED)
for
Pyrethrin,
Error
Correction
Incorporated.
(
March
24,
2005)

Docket
Entry
13.
Tier
1
Estimated
Drinking
Water
Concentration
of
Pyrethrin
and
Derivaties
for
use
in
Human
Health
Risk
Assessment.
(
August
19,
2005)

Docket
Entry
14.
EFED
Addendum
to
Pyrethrins
RED
Chapter.
(
May
3,
2005)

Phase
5
Federal
Register
and
Docket
Organizational
Documents:

Docket
Entry
35.
Federal
Register
Notice:
Pyrethrins
Revised
Risk
Assessments,
Notice
of
Availability,
and
Solicitation
of
Risk
Reduction
Options.

Docket
Entry
36.
Reader's
Guide
to
the
Pyrethrins
E­
Docket
#
OPP­
2005­
0043.(
UPDATED
September
21,
2005)

Phase
5
Human
Health
Risk
Assessments
Documents:

Docket
Entry
37.
Pyrethrins.
Response
Public
Comments
to
HED
Risk
Assessment
and
Supporting
Documents
Case
No.
2580.
DP
Barcode
No.:
D295745.
(
September
8,
2005)
Reader's
Guide
PYRETHRINS
CRM:
Cathryn
O'Connell
EPA/
OPPTS/
OPP/
SRRD
Page
3
of
6
Docket
Entry
38.
Pyrethrins:
Revised
Human
Health
Risk
Assessment
for
the
Reregistration
Eligibility
Decision.
Case
No.
2580.
PC
Code:
069001;
DP
Barcode:
D321641
(
September
14,
2005)

Docket
Entry
39.
Piperonyl
Butoxide
(
PBO),
Pyrethrins
and
MGK­
264:
Health
Effects
Division's
response
to
the
Registrant's
concerns
for
using
metaplasia
seen
in
the
larynx
in
subchronic
inhalation
studies
as
an
endpoint
for
inhalation
risk
assessment.
(
September
8,
2005)

Docket
Entry
40.
Pyrethrins.
Revised
Residue
Chemistry
Considerations
for
Reregistration
Eligibility
Decision.
Case
No.
2580.
(
September
8,
2005)

Docket
Entry
41.
Pyrethrins:
2nd
Revised
Occupational
and
Residential
Exposure
Assessment
and
Recommendations
for
The
Reregistration
Eligibility
Decision
(
RED).
[
PC
Code
069001,
DP
Barcode
D318630]
(
September
7,
2005)

Docket
Entry
42.
Occupational
and
Residential
Exposure
Assessment
for
the
Use
of
Pyrethrin
in
Residential
Mosquito
Mister
Systems.
(
September
7,
2005)

Docket
Entry
43.
Review
of
Pyrethrins
Incident
Reports
­
Second
Revision
DP
Barcode
D320300,
Chemical
#
069001
This
document
addresses
comments
made
in
regard
to
the
PBO
Incident
Report
(
5/
10/
05)
as
well.
(
August
16,
2005)

Phase
5
Ecological
Risk
Assessment
Documents:

Docket
Entry
44.
Responses
to
Registrant's
Comments
on
the
EFED
Draft
Risk
Assessment
for
the
Pyrethrins
During
the
60­
Day
Comment
Period
(
Division
Draft
RED
Chapter
dated
May
3,
2005,
DP
Barcode
D295740,
Docket
OPP­
2005­
0043).
(
September
7,
2005)

Docket
Entry
45.
Revised
Pyrethrins
RED
Chapter
After
60­
Day
Comment
Period
(
EFED)
(
September
9,
2005)

Docket
Entry
46.
Response
to
Public
Comments
on
the
Drinking
Water
Assessment
for
Pyrethrins.
Reader's
Guide
PYRETHRINS
CRM:
Cathryn
O'Connell
EPA/
OPPTS/
OPP/
SRRD
Page
4
of
6
(
September
6,
2005)

Additional
Phase
5
Documents:

Docket
Entry
47.
Pyrethrins
Consultation
Letter
from
Michael
McGeehin,
Dept.
of
Health
and
Human
Services,
CDC.
(
August
1,
2005)

Docket
Entry
48.
Intermittent
Aerosols,
Residential
Mosquito
Misters,
and
Dairy
Barn
Misters.
Submitted
by
the
Pyrethrin
Joint
Venture
(
Co.
No.
058223),
and
the
Piperonyl
Butoxide
Task
Force
II,
Case
2525,
Chemical
067501).
(
August
1,
2005)

Final
RED
Federal
Register
and
Docket
Organizational
Document:

Docket
Entry
72.
Federal
Register
Notice:
Pyrethrins
Reregistration
Eligibility
Decision;
Notice
of
Availability.

Docket
Entry
73.
Reader's
Guide
to
the
Pyrethrins
E­
Docket
#
OPP­
2005­
0043.
(
This
document,
version
July
26,
2006)

Pyrethrins
Reregistration
Eligibility
Decision
(
RED)
Document:

Docket
Entry
74.
Reregistration
Eligibility
Decision
(
RED)
for
Pyrethrins.
(
June
7,
2006)

RED
Human
Health
Risk
Assessments
Documents:

Docket
Entry
75.
Pyrethrins:
Revised
Human
Health
Risk
Assessment
for
the
Reregistration
Eligibility
Decision.
(
March
16,
2006)

Docket
Entry
76.
Pyrethrins:
Responses
to
Public
Comments
on
HED
Risk
Assessment
and
Supporting
Documents.
(
January
31,
2006)

Docket
Entry
77.
PYRETHRINS
Reregistration
Branch
1/
Health
Effects
Division
Response
to
Comments
on
Draft
Risk
Assessment.
(
August
17,
2005)

Docket
Entry
78.
Pyrethrins:
Occupational
Exposure
Assessment
for
Indoor
Fogging
Applications.
(
July
5,
2006)
Reader's
Guide
PYRETHRINS
CRM:
Cathryn
O'Connell
EPA/
OPPTS/
OPP/
SRRD
Page
5
of
6
Docket
Entry
79.
Revised
Occupational
and
Residential
Exposure
Assessment
for
the
Use
of
Pyrethrin
in
Residential
Mosquito
Mister
Systems.
(
July
12,
2006)

Docket
Entry
80.
Three
Pyrethrin
Health
Effects
Reviews:
Mosby
and
Registrant
Submissions.
(
July
2006)

RED
Ecological
Risk
Assessment
Documents:

Docket
Entry
81.
Revised
Pyrethrins
RED
Chapter
After
Additional
60­
Day
Comment
Period,
Phase
5.
(
February
16,
2006)

Docket
Entry
82.
APPENDICES
FOR:
Revised
Pyrethrins
RED
Chapter
After
Additional
60­
Day
Comment
Period,
Phase
5.
(
February
16,
2006)

Docket
Entry
83.
Response
to
Comments
of
Phase
5
Period
About
Water
Quality,
and
Other
Issues
on
the
Revised
Draft
EFED
RED
Chapters
for
Pyrethrins,
PBO
and
MGK­
264.
(
January
30,
2006)

Additional
Documents:

Docket
Entry
84.
Cover
Letter
to
the
National
Pest
Management
Association
(
NPMA)
regarding
Labeling
Options
for
Outdoor
Residential
Misting
Systems
(
February
2,
2006)

Docket
Entry
85.
Attachment
to
NPMA
Letter­
Mister
Labeling
Options.
(
February
2,
2006)

Registrant
CARES
Submission:

Three
pyrethrins
technical
registrants,
Valent
BioSciences
Corporation,
McLaughlin
Gormely
King
Company,
and
S.
C.
Johnson
and
Son,
Inc.,
submitted
a
refined
residential
aggregate
risk
assessment
for
the
pyrethrins.
The
original
transmittal
letter
and
report
is
being
posted
here
as
additional
reference
documents.

Docket
Entry
86.
Transmittal
Letter
for
the
"
Submission
of
Pyrethrins
CARES
Aggregate
Assessment
Report."
From
Valent
BioSciences
Corporation.
MRID:
46764300.
(
February
2,
2006)
Reader's
Guide
PYRETHRINS
CRM:
Cathryn
O'Connell
EPA/
OPPTS/
OPP/
SRRD
Page
6
of
6
Docket
Entry
87.
Pyrethrins:
Evaluation
of
Potential
Aggregate
Human
Health
Risks
Associated
with
Agricultural
and
Consumer
Uses.
MRID
46764301.
(
January
18,
2006)
