Reader's
Guide
PBO
CRM:
Cathryn
O'Connell
EPA/
OPPTS/
OPP/
SRRD
Page
1
of
5
Reader's
Guide
to
the
Piperonyl
Butoxide
(
PBO)
Reregistration
Eligibility
Decision
(
RED)
E­
Docket
#
OPP­
2005­
0042
Publication
Date:
July
26,
2006
EPA
has
created
this
document
to
provide
an
organizational
structure
to
the
Piperonyl
Butoxide
(
PBO)
E­
docket.
The
docket
index
lists
the
caption
entries
sequentially,
while
this
document
lists
them
by
subject
matter.
The
Agency
is
providing
the
"
Readers
Guide"
to
allow
the
reader
to
more
easily
access
and
navigate
the
various
entries
contained
in
the
Piperonyl
Butoxide
(
PBO)
E­
docket.

Phase
3
Federal
Register
and
Docket
Organizational
Documents:

Docket
Entry
1.
Federal
Register
Notice:
Piperonyl
Butoxide
(
PBO)
Risk
Assessments;
Notice
of
Availability.

Docket
Entry
2.
Reader's
Guide
to
the
Piperonyl
Butoxide
(
PBO)
E­
Docket
#
OPP­
2005­
0042.
(
April
27,
2005)

Docket
Entry
3.
Overview
of
the
Piperonyl
Butoxide
(
PBO)
Risk
Assessments.
(
May
4,
2005)

Phase
3
Human
Health
Risk
Assessments
Documents:

Docket
Entry
4.
Piperonyl
Butoxide
(
PBO)
HED
Risk
Assessments
for
Reregistration
Eligibility
Document
(
March
11,
2005)

Docket
Entry
5.
Piperonyl
Butoxide
(
PBO)
 
Reregistration
Eligibility
Decision.
Revised
Product
and
Residue
Chemistry
Considerations.
(
November
23,
2005)

Docket
Entry
6.
Occupational
and
Residential
Exposure
Assessment
and
Recommendations
for
the
RED
for
Piperonyl
Butoxide
(
PBO).
(
March
11,
2005)

Docket
Entry
7.
Piperonyl
Butoxide
(
PBO):
Revised
Metabolism
Assessment
Review
Committee
Report.
(
November
23,
2005)

Docket
Entry
8.
Piperonyl
Butoxide
(
PBO):
Revised
Anticipated
Residues
and
Acute
Probabilistic
Chronic
Dietary
Exposure
Assessment
for
the
RED.
(
November
23,
2004)
Reader's
Guide
PBO
CRM:
Cathryn
O'Connell
EPA/
OPPTS/
OPP/
SRRD
Page
2
of
5
Docket
Entry
9.
Piperonyl
Butoxide
(
PBO):
First
Report
of
the
Hazard
Identification
Assessment
Review
Committee.
(
June
8,
2004)

Docket
Entry
10.
Review
of
Piperonyl
Butoxide
(
PBO)
Incident
Reports.
(
May
10,
2004)

Phase
3
Ecological
Risk
Assessment
Documents:

Docket
Entry
11.
EFED
Response
to
Error­
Only
Review:
Ecological
Risk
Assessments
for
Piperonyl
Butoxide
(
PBO)
(
February
24,
2005)

Docket
Entry
12.
Screening
Ecological
Risk
Assessment
for
the
Piperonyl
Butoxide
(
PBO)
RED.
(
January
4,
2005)

Docket
Entry
13.
Tier
I
Drinking
Water
Assessment
for
Piperonyl
Butoxide
(
PBO).
(
May
17,
2004)

Phase
5
Federal
Register
and
Docket
Organizational
Documents:

Docket
Entry
26.
Federal
Register
Notice:
Piperonyl
butoxide
Revised
Risk
Assessments,
Notice
of
Availability,
and
Solicitation
of
Risk
Reduction
Options.

Docket
Entry
27.
Reader's
Guide
to
the
Piperonyl
Butoxide
(
PBO)
E­
Docket
#
OPP­
2005­
0042.
(
September
15,
2005)

Phase
5
Human
Health
Risk
Assessments
Documents:

Docket
Entry
28.
Piperonyl
Butoxide:
Response
to
Public
Comments
on
the
HED
Risk
Assessment
for
Piperonyl
Butoxide
RED
Chapter;
PC
Code
067501;
DP
Barcode:
321496
(
September
9,
2005)

Docket
Entry
29.
Piperonyl
Butoxide
HED
Revised
Risk
Assessment
for
Reregistration
Eligibility
Document
(
RED)
PC
Code
No
067501;
DP
Barcode
No.
318719
(
September
8,
2005)

Docket
Entry
30.
Piperonyl
Butoxide
(
PBO),
Pyrethrins
and
MGK­
264:
Health
Effects
Division's
response
to
the
Registrant's
concerns
for
using
metaplasia
seen
in
the
larynx
in
subchronic
inhalation
studies
as
an
endpoint
for
inhalation
risk
assessment.
Reader's
Guide
PBO
CRM:
Cathryn
O'Connell
EPA/
OPPTS/
OPP/
SRRD
Page
3
of
5
(
September
8,
2005)

Docket
Entry
31.
Piperonyl
Butoxide
(
PC
Code
067501):
Response
to
Phase
3
Comments
­
Toxicity
Document,
DP
Code:
D310025
(
September
14,
2005)

Docket
Entry
32.
Revised
Occupational
and
Residential
Exposure
Assessment
And
Recommendations
For
The
Reregistration
Eligibility
Decision
(
RED)
for
Piperonyl
Butoxide
(
September
8,
2005)

Docket
Entry
33.
Occupational
and
Residential
Exposure
Assessment
for
the
Use
of
Piperonyl
Butoxide
in
Residential
Outdoor
Automatic
Mister
System.
(
August
30,
2005)

Docket
Entry
34.
Piperonyl
Butoxide:
Revised
Metabolism
Assessment
Review
Committee
Report
(
September
1,
2005)

Docket
Entry
35.
Review
of
Pyrethrins
Incident
Reports
­
Second
Revision
DP
Barcode
D320300,
Chemical
#
069001
This
document
addresses
comments
made
in
regard
to
the
PBO
Incident
Report
(
5/
10/
05)
as
well.
(
August
16,
2005)

Phase
5
Ecological
Risk
Assessment
Documents:

Docket
Entry
36.
Piperonyl
butoxide:
EFED
Response
to
Public
Comments
and
our
Revised
Ecological
Risk
Assessment.
(
September
6,
2005)

Docket
Entry
37.
Piperonyl
butoxide
Risk
Assessment.
Provided
for
SRRD
by
EFED's
Piperonyl
Butoxide
RED
Team.
(
September
2005)

Additional
Phase
5
Documents:

Docket
Entry
38.
Pyrethrins
Consultation
Letter
from
Michael
McGeehin,
Dept.
of
Health
and
Human
Services,
CDC.
This
document
also
addresses
PBO.
(
August
1,
2005)

Docket
Entry
39.
Intermittent
Aerosols,
Residential
Mosquito
Misters,
and
Dairy
Barn
Misters.
Submitted
by
the
Pyrethrin
Joint
Reader's
Guide
PBO
CRM:
Cathryn
O'Connell
EPA/
OPPTS/
OPP/
SRRD
Page
4
of
5
Venture
(
Co.
No.
058223),
and
the
Piperonyl
Butoxide
Task
Force
II,
Case
2525,
Chemical
067501).
(
August
1,
2005)

Final
RED
Federal
Register
and
Docket
Organizational
Document:

Docket
Entry
55.
Federal
Register
Notice:
Piperonyl
Butoxide
Reregistration
Eligibility
Decision;
Notice
of
Availability.

Docket
Entry
56.
Reader's
Guide
to
the
Piperonyl
Butoxide
E­
Docket
#
OPP­
2005­
0042.
(
This
document,
version
July
26,
2006)

Piperonyl
Butoxide
Reregistration
Eligibility
Decision
(
RED)
Document:

Docket
Entry
57.
Reregistration
Eligibility
Decision
(
RED)
for
Piperonyl
Butoxide.
(
June
14,
2006)

RED
Human
Health
Risk
Assessments
Documents:

Docket
Entry
58.
Piperonyl
Butoxide
HED
Revised
Risk
Assessment
for
Reregistration
Eligibility
Document
(
RED).
(
February
21,
2006)

Docket
Entry
59.
Piperonyl
Butoxide:
Response
to
Public
Comments
on
the
HED
Risk
Assessment
for
Piperonyl
Butoxide
RED
Chapter.
(
January
31,
2006)

Docket
Entry
60.
Piperonyl
Butoxide:
Addendum
to
Occupational
and
Residential
Exposure
Assessment.
(
July
5,
2006)

Docket
Entry
61.
Piperonyl
Butoxide:
Risk­
Based
Application
Rate
for
Residential
Outdoor
Automatic
Mister
Systems.
(
July
5,
2006)

RED
Ecological
Risk
Assessment
Documents:

Docket
Entry
62.
Response
to
Comments
of
Phase
5
Period
about
Water
Quality,
and
Other
Issues
on
the
Revised
Draft
EFED
RED
Chapters
for
Pyrethrins,
PBO
and
MGK­
264.
(
January
30,
2006)
Reader's
Guide
PBO
CRM:
Cathryn
O'Connell
EPA/
OPPTS/
OPP/
SRRD
Page
5
of
5
Additional
Documents:

Docket
Entry
63.
Cover
Letter
to
the
National
Pest
Management
Association
(
NPMA)
regarding
Labeling
Options
for
Outdoor
Residential
Misting
Systems
(
February
2,
2006)

Docket
Entry
64.
Attachment
to
NPMA
Letter­
Mister
Labeling
Options.
(
February
2,
2006)
