UNITED
STATES
ENVIRONMENTAL
PROTECTION
AGENCY
WASHINGTON,
D.
C.
20460
OFFICE
OF
PREVENTION,
PESTICIDES
AND
TOXIC
SUBSTANCES
October
6,
2004
MEMORANDUM
SUBJECT:
Review
of
MGK­
264
Incident
Reports
DP
Barcode
D306591,
Chemical#
057001
FROM:
Jerome
Blondell,
Ph.
D.,
Health
Statistician
Chemistry
and
Exposure
Branch
Health
Effects
Division
(
7509C)

THRU:
Francis
B.
Suhre,
Chief
Chemistry
and
Exposure
Branch
Health
Effects
Division
(
7509C)

TO:
Mary
Elissa
Reaves,
Toxicologist
Reregistration
Branch
2
Health
Effects
Division
(
7509C)

BACKGROUND
The
following
data
bases
have
been
consulted
for
the
poisoning
incident
data
on
the
active
ingredient
MGK­
264
(
PC
Code:
057001):

1)
OPP
Incident
Data
System
(
IDS)
­
reports
of
incidents
from
various
sources,
including
registrants,
other
federal
and
state
health
and
environmental
agencies
and
individual
consumers,
submitted
to
OPP
since
1992.
Reports
submitted
to
the
Incident
Data
System
represent
anecdotal
reports
or
allegations
only,
unless
otherwise
stated.
Typically
no
conclusions
can
be
drawn
implicating
the
pesticide
as
a
cause
of
any
of
the
reported
health
effects.
Nevertheless,
sometimes
with
enough
cases
and/
or
enough
documentation
risk
mitigation
measures
may
be
suggested.

2)
Poison
Control
Centers
­
as
the
result
of
a
data
purchase
by
EPA,
OPP
received
Poison
2
Control
Center
data
covering
the
years
1993
through
1998
for
all
pesticides.
Most
of
the
national
Poison
Control
Centers
(
PCCs)
participate
in
a
national
data
collection
system,
the
Toxic
Exposure
Surveillance
System
which
obtains
data
from
about
65­
70
centers
at
hospitals
and
universities.
PCCs
provide
telephone
consultation
for
individuals
and
health
care
providers
on
suspected
poisonings,
involving
drugs,
household
products,
pesticides,
etc.

3)
California
Department
of
Pesticide
Regulation
­
California
has
collected
uniform
data
on
suspected
pesticide
poisonings
since
1982.
Physicians
are
required,
by
statute,
to
report
to
their
local
health
officer
all
occurrences
of
illness
suspected
of
being
related
to
exposure
to
pesticides.
The
majority
of
the
incidents
involve
workers.
Information
on
exposure
(
worker
activity),
type
of
illness
(
systemic,
eye,
skin,
eye/
skin
and
respiratory),
likelihood
of
a
causal
relationship,
and
number
of
days
off
work
and
in
the
hospital
are
provided.

4)
National
Pesticide
Telecommunications
Network
(
NPTN)
­
NPTN
is
a
toll­
free
information
service
supported
by
OPP.
A
ranking
of
the
top
200
active
ingredients
for
which
telephone
calls
were
received
during
calendar
years
1984­
1991,
inclusive
has
been
prepared.
The
total
number
of
calls
was
tabulated
for
the
categories
human
incidents,
animal
incidents,
calls
for
information,
and
others.

MGK­
264
REVIEW
MGK­
264
is
used
in
a
wide
variety
of
differing
formulations.
It
is
always
mixed
with
other
active
ingredients
and
never
used
alone.
There
is
no
set
of
products
identified
containing
certain
active
ingredients
with
MGK­
264
and
another
set
of
products
with
the
same
set
of
active
ingredients
but
without
MGK­
264.
A
comparison
between
two
such
sets
of
products
would
have
permitted
identification
of
effects
likely
due
to
MGK­
264.
Given
the
absence
of
two
such
sets
of
products
and
the
absence
of
incidents
due
solely
to
MGK­
264
it
is
not
possible
to
complete
an
incident
review
for
this
active
ingredient.

VI.
Conclusion
An
incident
review
of
MGK­
264
was
not
possible
because
it
is
always
part
of
various
mixtures
where
it's
contribution
to
the
ill
effects
cannot
be
determined..

VII.
Recommendations
No
recommendations
are
made
for
MGK­
264.

cc:
MGK­
264
file
(
057001)
