42035
Federal
Register
/
Vol.
68,
No.
136
/
Wednesday,
July
16,
2003
/
Notices
no
developmental
(
pup)
or
reproductive
effects
up
to
45.0
mg/
kg/
day,
HDT.
iv.
Prenatal
and
postnatal
sensitivity
 
i.
Prenatal.
There
was
no
evidence
of
developmental
toxicity
in
the
studies
at
the
HDT
in
the
rat
(
70.0
mg/
kg/
day)
or
in
the
rabbit
(
700
mg/
kg/
day).
Therefore,
there
is
no
evidence
of
a
special
dietary
risk
(
either
acute
or
chronic)
for
infants
and
children
which
would
require
an
additional
safety
factor.
v.
Postnatal.
Based
on
the
absence
of
pup
toxicity
up
to
dose
levels
which
produced
toxicity
in
the
parental
animals,
there
is
no
evidence
of
special
postnatal
sensitivity
to
infants
and
children
in
the
rat
reproduction
study.
vi.
Conclusion.
Based
on
the
above,
FMC
Corporation
concludes
that
reliable
data
support
use
of
the
standard
100­
fold
UF,
and
that
an
additional
UF
is
not
needed
to
protect
the
safety
of
infants
and
children.
As
stated
above,
aggregate
exposure
assessments
utilized
significantly
less
than
1%
of
the
RfD
for
either
the
entire
U.
S.
population
or
any
of
the
26
population
subgroups
including
infants
and
children.
Therefore,
it
may
be
concluded
that
there
is
reasonable
certainty
that
no
harm
will
result
to
infants
and
children
from
aggregate
exposure
to
cypermethrin
residues.

F.
International
Tolerances
There
are
no
Canadian,
or
Mexican
residue
limits,
for
residues
of
cypermethrin
or
zeta­
cypermethrin
in
or
on
pome
fruits
crop
group
or
stone
fruits
crop
group.
The
codex
maximum
residue
levels
for
cypermethrin
are
2.0
ppm
for
nectarine,
2.0
ppm
for
peaches,
1.0
for
plums
(
including
prunes),
and
2.0
ppm
for
pome
fruits.
[
FR
Doc.
03
 
17898
Filed
7
 
15
 
03;
8:
45
am]

BILLING
CODE
6560
 
50
 
S
ENVIRONMENTAL
PROTECTION
AGENCY
[
OPP
 
2003
 
0233;
FRL
 
7316
 
2]

Cis­
3­
hexen­
1­
ol;
Notice
of
Filing
a
Pesticide
Petition
to
Establish
a
Tolerance
for
a
Certain
Pesticide
Chemical
in
or
on
Food
AGENCY:
Environmental
Protection
Agency
(
EPA).
ACTION:
Notice.

SUMMARY:
This
notice
announces
the
initial
filing
of
a
pesticide
petition
proposing
the
establishment
of
regulations
for
residues
of
a
certain
pesticide
chemical
in
or
on
various
food
commodities.
DATES:
Comments,
identified
by
docket
ID
number
OPP
 
2003
 
0233,
must
be
received
on
or
before
August
15,
2003.
ADDRESSES:
Comments
may
be
submitted
electronically,
by
mail,
or
through
hand
delivery/
courier.
Follow
the
detailed
instructions
as
provided
in
Unit
I.
of
the
SUPPLEMENTARY
INFORMATION.

FOR
FURTHER
INFORMATION
CONTACT:
Kathryn
Boyle,
Registration
Division
(
7505C),
Office
of
Pesticide
Programs,
Environmental
Protection
Agency,
1200
Pennsylvania
Ave.,
NW.,
Washington,
DC
20460
 
0001;
telephone
number:
(
703)
305
 
6304;
e­
mail
address:
boyle.
kathryn@
epa.
gov.

SUPPLEMENTARY
INFORMATION:

I.
General
Information
A.
Does
this
Action
Apply
to
Me?

You
may
be
potentially
affected
by
this
action
if
you
are
an
agricultural
producer,
food
manufacturer,
or
pesticide
manufacturer.
Potentially
affected
entities
may
include,
but
are
not
limited
to:
 
Crop
production
(
NAICS
code
111)
 
Animal
production
(
NASICS
code
112)
 
Food
manufacturing
(
NAICS
code
311)
 
Pesticide
manufacturing
(
NAICS
code
32532)
This
listing
is
not
intended
to
be
exhaustive,
but
rather
provides
a
guide
for
readers
regarding
entities
likely
to
be
affected
by
this
action.
Other
types
of
entities
not
listed
in
this
unit
could
also
be
affected.
The
North
American
Industrial
Classification
System
(
NAICS)
codes
have
been
provided
to
assist
you
and
others
in
determining
whether
this
action
might
apply
to
certain
entities.
If
you
have
any
questions
regarding
the
applicability
of
this
action
to
a
particular
entity,
consult
the
person
listed
under
FOR
FURTHER
INFORMATION
CONTACT.

B.
How
Can
I
Get
Copies
of
this
Document
and
Other
Related
Information?

1.
Docket.
EPA
has
established
an
official
public
docket
for
this
action
under
docket
identification
(
ID)
number
OPP
 
2003
 
0233.
The
official
public
docket
consists
of
the
documents
specifically
referenced
in
this
action,
any
public
comments
received,
and
other
information
related
to
this
action.
Although
a
part
of
the
official
docket,
the
public
docket
does
not
include
Confidential
Business
Information
(
CBI)
or
other
information
whose
disclosure
is
restricted
by
statute.
The
official
public
docket
is
the
collection
of
materials
that
is
available
for
public
viewing
at
the
Public
Information
and
Records
Integrity
Branch
(
PIRIB),
Rm.
119,
Crystal
Mall
#
2,
1921
Jefferson
Davis
Hwy.,
Arlington,
VA.
This
docket
facility
is
open
from
8:
30
a.
m.
to
4
p.
m.,
Monday
through
Friday,
excluding
legal
holidays.
The
docket
telephone
number
is
(
703)
305
 
5805.
2.
Electronic
access.
You
may
access
this
Federal
Register
document
electronically
through
the
EPA
Internet
under
the
``
Federal
Register''
listings
at
http://
www.
epa.
gov/
fedrgstr/.
An
electronic
version
of
the
public
docket
is
available
through
EPA's
electronic
public
docket
and
comment
system,
EPA
Dockets.
You
may
use
EPA
Dockets
at
http://
www.
epa.
gov/
edocket/
to
submit
or
view
public
comments,
access
the
index
listing
of
the
contents
of
the
official
public
docket,
and
to
access
those
documents
in
the
public
docket
that
are
available
electronically.
Although
not
all
docket
materials
may
be
available
electronically,
you
may
still
access
any
of
the
publicly
available
docket
materials
through
the
docket
facility
identified
in
Unit
I.
B.
1.
Once
in
the
system,
select
``
search,''
then
key
in
the
appropriate
docket
ID
number.
Certain
types
of
information
will
not
be
placed
in
the
EPA
Dockets.
Information
claimed
as
CBI
and
other
information
whose
disclosure
is
restricted
by
statute,
which
is
not
included
in
the
official
public
docket,
will
not
be
available
for
public
viewing
in
EPA's
electronic
public
docket.
EPA's
policy
is
that
copyrighted
material
will
not
be
placed
in
EPA's
electronic
public
docket
but
will
be
available
only
in
printed,
paper
form
in
the
official
public
docket.
To
the
extent
feasible,
publicly
available
docket
materials
will
be
made
available
in
EPA's
electronic
public
docket.
When
a
document
is
selected
from
the
index
list
in
EPA
Dockets,
the
system
will
identify
whether
the
document
is
available
for
viewing
in
EPA's
electronic
public
docket.
Although
not
all
docket
materials
may
be
available
electronically,
you
may
still
access
any
of
the
publicly
available
docket
materials
through
the
docket
facility
identified
in
Unit
I.
B.
EPA
intends
to
work
towards
providing
electronic
access
to
all
of
the
publicly
available
docket
materials
through
EPA's
electronic
public
docket.
For
public
commenters,
it
is
important
to
note
that
EPA's
policy
is
that
public
comments,
whether
submitted
electronically
or
in
paper,
will
be
made
available
for
public
viewing
in
EPA's
electronic
public
docket
as
EPA
receives
them
and
without
change,
unless
the
comment
contains
copyrighted
material,
CBI,
or
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17:
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42036
Federal
Register
/
Vol.
68,
No.
136
/
Wednesday,
July
16,
2003
/
Notices
other
information
whose
disclosure
is
restricted
by
statute.
When
EPA
identifies
a
comment
containing
copyrighted
material,
EPA
will
provide
a
reference
to
that
material
in
the
version
of
the
comment
that
is
placed
in
EPA's
electronic
public
docket.
The
entire
printed
comment,
including
the
copyrighted
material,
will
be
available
in
the
public
docket.
Public
comments
submitted
on
computer
disks
that
are
mailed
or
delivered
to
the
docket
will
be
transferred
to
EPA's
electronic
public
docket.
Public
comments
that
are
mailed
or
delivered
to
the
docket
will
be
scanned
and
placed
in
EPA's
electronic
public
docket.
Where
practical,
physical
objects
will
be
photographed,
and
the
photograph
will
be
placed
in
EPA's
electronic
public
docket
along
with
a
brief
description
written
by
the
docket
staff.

C.
How
and
To
Whom
Do
I
Submit
Comments?
You
may
submit
comments
electronically,
by
mail,
or
through
hand
delivery/
courier.
To
ensure
proper
receipt
by
EPA,
identify
the
appropriate
docket
ID
number
in
the
subject
line
on
the
first
page
of
your
comment.
Please
ensure
that
your
comments
are
submitted
within
the
specified
comment
period.
Comments
received
after
the
close
of
the
comment
period
will
be
marked
``
late.''
EPA
is
not
required
to
consider
these
late
comments.
If
you
wish
to
submit
CBI
or
information
that
is
otherwise
protected
by
statute,
please
follow
the
instructions
in
Unit
I.
D.
Do
not
use
EPA
Dockets
or
e­
mail
to
submit
CBI
or
information
protected
by
statute.
1.
Electronically.
If
you
submit
an
electronic
comment
as
prescribed
in
this
unit,
EPA
recommends
that
you
include
your
name,
mailing
address,
and
an
email
address
or
other
contact
information
in
the
body
of
your
comment.
Also
include
this
contact
information
on
the
outside
of
any
disk
or
CD
ROM
you
submit,
and
in
any
cover
letter
accompanying
the
disk
or
CD
ROM.
This
ensures
that
you
can
be
identified
as
the
submitter
of
the
comment
and
allows
EPA
to
contact
you
in
case
EPA
cannot
read
your
comment
due
to
technical
difficulties
or
needs
further
information
on
the
substance
of
your
comment.
EPA's
policy
is
that
EPA
will
not
edit
your
comment,
and
any
identifying
or
contact
information
provided
in
the
body
of
a
comment
will
be
included
as
part
of
the
comment
that
is
placed
in
the
official
public
docket,
and
made
available
in
EPA's
electronic
public
docket.
If
EPA
cannot
read
your
comment
due
to
technical
difficulties
and
cannot
contact
you
for
clarification,
EPA
may
not
be
able
to
consider
your
comment.
i.
EPA
Dockets.
Your
use
of
EPA's
electronic
public
docket
to
submit
comments
to
EPA
electronically
is
EPA's
preferred
method
for
receiving
comments.
Go
directly
to
EPA
Dockets
at
http://
www.
epa.
gov/
edocket,
and
follow
the
online
instructions
for
submitting
comments.
Once
in
the
system,
select
``
search,''
and
then
key
in
docket
ID
number
OPP
 
2003
 
0233.
The
system
is
an
``
anonymous
access''
system,
which
means
EPA
will
not
know
your
identity,
e­
mail
address,
or
other
contact
information
unless
you
provide
it
in
the
body
of
your
comment.
ii.
E­
mail.
Comments
may
be
sent
by
e­
mail
to
opp­
docket@
epa.
gov,
Attention:
Docket
ID
Number
OPP
 
2003
 
0233.
In
contrast
to
EPA's
electronic
public
docket,
EPA's
e­
mail
system
is
not
an
``
anonymous
access''
system.
If
you
send
an
e­
mail
comment
directly
to
the
docket
without
going
through
EPA's
electronic
public
docket,
EPA's
e­
mail
system
automatically
captures
your
e­
mail
address.
E­
mail
addresses
that
are
automatically
captured
by
EPA's
e­
mail
system
are
included
as
part
of
the
comment
that
is
placed
in
the
official
public
docket,
and
made
available
in
EPA's
electronic
public
docket.
iii.
Disk
or
CD
ROM.
You
may
submit
comments
on
a
disk
or
CD
ROM
that
you
mail
to
the
mailing
address
identified
in
Unit
I.
C.
2.
These
electronic
submissions
will
be
accepted
in
WordPerfect
or
ASCII
file
format.
Avoid
the
use
of
special
characters
and
any
form
of
encryption.
2.
By
mail.
Send
your
comments
to:
Public
Information
and
Records
Integrity
Branch
(
PIRIB)
(
7502C),
Office
of
Pesticide
Programs
(
OPP),
Environmental
Protection
Agency,
1200
Pennsylvania
Ave.,
NW.,
Washington,
DC
20460
 
0001,
Attention:
Docket
ID
Number
OPP
 
2003
 
0233.
3.
By
hand
delivery
or
courier.
Deliver
your
comments
to:
Public
Information
and
Records
Integrity
Branch
(
PIRIB),
Office
of
Pesticide
Programs
(
OPP),
Environmental
Protection
Agency,
Rm.
119,
Crystal
Mall
#
2,
1921
Jefferson
Davis
Hwy.,
Arlington,
VA,
Attention:
Docket
ID
Number
OPP
 
2003
 
0233.
Such
deliveries
are
only
accepted
during
the
docket's
normal
hours
of
operation
as
identified
in
Unit
I.
B.
1.

D.
How
Should
I
Submit
CBI
To
the
Agency?
Do
not
submit
information
that
you
consider
to
be
CBI
electronically
through
EPA's
electronic
public
docket
or
by
e­
mail.
You
may
claim
information
that
you
submit
to
EPA
as
CBI
by
marking
any
part
or
all
of
that
information
as
CBI
(
if
you
submit
CBI
on
disk
or
CD
ROM,
mark
the
outside
of
the
disk
or
CD
ROM
as
CBI
and
then
identify
electronically
within
the
disk
or
CD
ROM
the
specific
information
that
is
CBI).
Information
so
marked
will
not
be
disclosed
except
in
accordance
with
procedures
set
forth
in
40
CFR
part
2.
In
addition
to
one
complete
version
of
the
comment
that
includes
any
information
claimed
as
CBI,
a
copy
of
the
comment
that
does
not
contain
the
information
claimed
as
CBI
must
be
submitted
for
inclusion
in
the
public
docket
and
EPA's
electronic
public
docket.
If
you
submit
the
copy
that
does
not
contain
CBI
on
disk
or
CD
ROM,
mark
the
outside
of
the
disk
or
CD
ROM
clearly
that
it
does
not
contain
CBI.
Information
not
marked
as
CBI
will
be
included
in
the
public
docket
and
EPA's
electronic
public
docket
without
prior
notice.
If
you
have
any
questions
about
CBI
or
the
procedures
for
claiming
CBI,
please
consult
the
person
listed
under
FOR
FURTHER
INFORMATION
CONTACT.

E.
What
Should
I
Consider
as
I
Prepare
My
Comments
for
EPA?

You
may
find
the
following
suggestions
helpful
for
preparing
your
comments:
1.
Explain
your
views
as
clearly
as
possible.
2.
Describe
any
assumptions
that
you
used.
3.
Provide
copies
of
any
technical
information
and/
or
data
you
used
that
support
your
views.
4.
If
you
estimate
potential
burden
or
costs,
explain
how
you
arrived
at
the
estimate
that
you
provide.
5.
Provide
specific
examples
to
illustrate
your
concerns.
6.
Make
sure
to
submit
your
comments
by
the
deadline
in
this
notice.
7.
To
ensure
proper
receipt
by
EPA,
be
sure
to
identify
the
docket
ID
number
assigned
to
this
action
in
the
subject
line
on
the
first
page
of
your
response.
You
may
also
provide
the
name,
date,
and
Federal
Register
citation.

II.
What
Action
is
the
Agency
Taking?

EPA
has
received
a
pesticide
petition
as
follows
proposing
the
establishment
and/
or
amendment
of
regulations
for
residues
of
a
certain
pesticide
chemical
in
or
on
various
food
commodities
under
section
408
of
the
Federal
Food,
Drug,
and
Cosmetic
Act
(
FFDCA),
21
U.
S.
C.
346a.
EPA
has
determined
that
this
petition
contains
data
or
information
regarding
the
elements
set
forth
in
FFDCA
section
408(
d)(
2);
however,
EPA
has
not
fully
evaluated
the
sufficiency
of
the
submitted
data
at
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July
16,
2003
/
Notices
this
time
or
whether
the
data
support
granting
of
the
petition.
Additional
data
may
be
needed
before
EPA
rules
on
the
petition.

List
of
Subjects
Environmental
protection,
Agricultural
commodities,
Feed
additives,
Food
additives,
Pesticides
and
pests,
Reporting
and
recordkeeping
requirements.

Dated:
July
2,
2003.
Debra
Edwards,
Director,
Registration
Division,
Office
of
Pesticide
Programs.

Summary
of
Petition
The
petitioner's
summary
of
the
pesticide
petition
is
printed
below
as
required
by
FFDCA
section
408(
d)(
3).
The
summary
of
the
petition
was
prepared
by
the
petitioner
and
represents
the
view
of
the
petitioner.
EPA
may
have
edited
the
summary
if
the
terminology
used
was
unclear,
the
summary
contained
extraneous
material,
or
the
summary
unintentionally
made
the
reader
conclude
that
the
findings
reflected
EPA's
position
and
not
the
position
of
the
petitioner.
The
petition
announces
the
availability
of
a
description
of
the
analytical
methods
available
to
EPA
for
the
detection
and
measurement
of
the
pesticide
chemical
residues
or
an
explanation
of
why
no
such
method
is
needed.

Syngenta
Crop
Protection
PP
3E6569
EPA
has
received
a
pesticide
petition
(
PP
3E6569)
from
Syngenta
Crop
Protection,
Inc.,
P.
O.
Box
18300,
Greensboro,
NC
27419
proposing,
pursuant
to
section
408(
d)
of
the
FFDCA,
21
U.
S.
C.
346a(
d),
to
amend
40
CFR
part
180
to
establish
an
exemption
from
the
requirement
of
a
tolerance
for
cis­
3­
hexen­
1­
ol
when
used
as
an
inert
ingredient
in
pesticide
formulations
containing
the
active
ingredient
paraquat
dichloride.
EPA
has
determined
that
the
petition
contains
data
or
information
regarding
the
elements
set
forth
in
section
408(
d)(
2)
of
the
FFDCA;
however,
EPA
has
not
fully
evaluated
the
sufficiency
of
the
submitted
data
at
this
time
or
whether
the
data
supports
granting
of
the
petition.
Additional
data
may
be
needed
before
EPA
rules
on
the
petition.

A.
Residue
Chemistry
1.
Plant
metabolism.
The
plant
metabolism
of
cis­
3­
hexen­
1­
ol
has
not
been
investigated.
However,
cis­
3­
hexen­
1­
ol
has
been
commonly
detected
as
a
volatile
organic
emission
from
a
number
of
plant
species.
Cis­
3­
Hexen­
1­
ol
is
also
a
naturally
occurring
aromatic
substance
in
a
number
of
food
products.
Cis­
3­
Hexen­
1­
ol,
is
a
terminal
metabolite
of
the
fatty
acid/
lipoxygenase
pathway
catalyzing
the
normal
oxidative
breakdown
of
plant
membrane
lipids.
2.
Analytical
method.
No
specific
analytical
method
is
provided
since
the
petition
is
for
an
exemption
from
the
requirement
of
establishing
a
tolerance
for
cis­
3­
hexen­
1­
ol.
However,
cis­
3­
hexen­
1­
ol
has
been
routinely
detected
in
both
raw
agricultural
commodities
and
in
processed
foods
by
gas
chromatography,
mass
spectroscopy,
or
a
combination
of
both.
These
methods
could
be
readily
developed
and
adapted
to
detect
cis­
3­
hexen­
1­
ol
in
food
products
to
which
paraquat
dichloride
may
be
applied.
3.
Magnitude
of
residues.
Potential
residues
of
cis­
3­
hexen­
1­
ol
in
raw
and
or
processed
agricultural
commodities
are
expected
to
be
minimal.
Cis­
3­
hexen­
1­
ol
would
be
present
at
a
concentration
of
up
to
4
grams/
L
only
in
pesticide
formulations
containing
paraquat
dichloride.
The
maximum
concentration
of
cis­
3­
hexen­
1­
ol
(
4
grams/
L)
in
paraquat
dichloride
formulations
is
much
lower
than
the
concentration
of
the
co­
formulated
active
ingredient
(
paraquat
dichloride).
Based
on
data
presented
in
the
reregistration
eligibility
document
on
paraquat
dichloride,
and
on
the
expected
relative
concentrations
of
paraquat
and
cis­
3­
hexenol
in
end
use
formulations,
residues
of
cis­
3­
hexen­
1­
ol
on
agricultural
commodities
would
be
at
least
50­
fold
lower
than
paraquat
dichloride.
Under
field
conditions,
the
residues
of
cis­
3­
hexen­
1­
ol
are
expected
to
be
even
lower
since
cis­
3­
hexen­
1­
ol
is
a
volatile
organic
compound
with
a
substantially
higher
vapor
pressure
than
paraquat
dichloride.

B.
Toxicological
Profile
1.
Acute
toxicity.
The
acute
oral
toxicity
of
cis­
3­
hexen­
1­
ol
has
been
evaluated
in
both
rats
and
mice.
The
oral
lethal
dose
(
LD)
50
for
cis­
3­
hexen­
1­
ol
in
rats
was
reported
to
be
4,700
milligrams/
kilograms
(
mg/
kg)
body
weight,
with
a
95%
confidence
interval
of
3,820
to
5,580
mg/
kg
body
weight.
In
this
study,
most
deaths
occurred
within
3
hours
of
dosing,
with
all
deaths
occurring
within
the
first
24
hours
postdosing
Clinical
signs
observed
prior
to
death
included
ataxia
followed
by
decreased
spontaneous
movement
and
development
of
a
comatose
state.
Necropsy
evaluations
revealed
no
specific
abnormalities
in
any
of
the
rats,
including
decedents.
Oral
lethal
dose
(
LD)
50
values
of
between
7,000
and
10,000
mg/
kg
body
weight
have
also
been
reported
for
both
rats
and
mice.
Rats
and
mice
were
considerably
more
sensitive
to
the
intraperitoneal
administration
of
cis­
3­
hexen­
1­
ol,
with
reported
i.
p.
LD50
values
of
600
and
400
to
500
mg/
kg
body
weight,
respectively.
Cis­
3­
Hexen­
1­
ol
was
essentially
nontoxic
by
the
dermal
route,
with
a
dermal
LD50
value
of
greater
than
5,000
mg/
kg
body
weight
(
the
highest
dose
tested)
in
rabbits.
Similarly,
the
application
of
neat
solutions
of
cis­
3­
hexen­
1­
ol,
held
under
an
occlusive
dressing
for
24
hours,
to
both
the
intact
and
abraded
skin
of
rabbits
was
found
to
be
nonirritating
In
human
subjects,
no
dermal
irritation
was
reported
following
application
of
a
4%
cis­
3­
hexen­
1­
ol
preparation
in
petrolatum
held
under
an
occlusive
patch
for
48
hours.
In
addition,
the
cis­
3­
hexen­
1­
ol
preparation
produced
no
evidence
of
sensitization
in
a
maximization
test
conducted
with
25
human
volunteers.
The
acute
toxicity
data
available
for
cis­
3­
hexen­
1­
ol
are
consistent
with
the
data
on
related
linear
and
branched
chain
aliphatic
unsaturated/
unconjugated
alcohols,
aldehydes,
and
esters,
showing
this
class
of
substances
to
be
of
low
toxicity
when
administered
orally.
2.
Genotoxicty.
The
genotoxicity
of
cis­
3­
hexen­
1­
ol
has
not
been
formally
investigated.
However,
cis­
3­
hexen­
1­
ol
contains
no
structural
alerts
for
genotoxic
potential.
Cis­
3­
Hexen­
1­
ol
is
expected
to
be
oxidized
to
the
corresponding
aldehyde
and
carboxylic
acid
by
high
capacity
carbohydrate
metabolic
pathways
(
i.
e.,
NAD+/
NADHdependent
metabolism
to
cis­
3­
hexenal
followed
by
aldehyde
dehydrogenasemediated
conversion
to
cis­
3­
hexenoic
acid).
Products
of
these
metabolic
pathways
are
not
anticipated
to
show
genotoxic
activity.
Information
available
on
substances
structurally
related
to
cis­
3­
hexen­
1­
ol
provides
no
evidence
of
mutagenic
or
chromosome­
damaging
potential.
For
example,
in
various
reverse
mutation
assays
conducted
in
bacterial
cultures,
oleic
acid,
methyl
linoleate,
and
2,6­
dimethyl­
5­
heptenal
were
reported
to
show
no
evidence
of
mutagenic
activity.
Similarly,
2,6­
dimethyl­
5­
heptenal
was
reported
to
show
no
genotoxic
activity
in
an
in
vitro
unscheduled
DNA
synthesis
test
or
in
an
in
vivo
mouse
micronucleus
test.
Also,
the
longer
chain
saturated
aliphatic
alcohols
octadecan­
1­
ol
and
tetradecan­
1­
ol
have
been
reported
to
be
non­
mutagenic
in
the
Ames
test
conducted
with
Salmonella
VerDate
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Vol.
68,
No.
136
/
Wednesday,
July
16,
2003
/
Notices
typhimurium
strains
TA98,
TA100,
TA1535,
TA1537,
and
TA1538.
3.
Reproductive
and
developmental
toxicity.
No
reproductive
or
developmental
toxicity
studies
on
cis­
3­
hexen­
1­
ol
were
identified
in
the
scientific
literature.
Given
the
metabolism
of
cis­
3­
hexen­
1­
ol
to
endogenous
substrates
of
fatty
acid
oxidation
pathways,
or
to
readily
excreted
carboxylic
acids,
it
is
not
expected
to
be
a
reproductive
toxicant.
A
teratogenicity
study
has
been
conducted
on
4­
pentenoic
acid,
a
substance
similar
to
the
potential
carboxylic
acid
metabolites
of
cis­
3­
hexen­
1­
ol.
In
this
study,
2
groups
of
15
female
NMRI
mice
were
mated
with
males
for
a
period
of
2
hours,
and,
on
day
8
of
gestation,
were
administered,
by
subcutaneous
injection,
the
sodium
salt
of
4­
pentenoic
acid
as
a
single
600
mg/
kg
body
weight
dose.
Implantation
sites
were
counted
and
each
live
fetus
was
weighed
and
examined
for
neural
tube
defects
and
any
other
visceral
or
skeletal
abnormalities.
The
study
authors
concluded
that
4­
pentenoic
acid
had
no
effect
on
embryo
survival,
the
number
of
live
fetuses,
fetal
weight,
or
on
the
incidence
of
neural
tube
defects.
There
were
no
reports
of
effects
of
4­
pentenoic
acid
on
the
incidence
rates
of
other
visceral
or
skeletal
abnormalities.
Summaries
of
two
reproductive
toxicity
studies
on
higher
chain
length
saturated
primary
alcohols
also
demonstrated
lack
of
toxicity.
In
these
1­
generation
reproductive
toxicity
studies,
dodecan­
1­
ol
or
octadecan­
1­
ol
was
administered
in
the
diet
to
groups
of
male
and
female
rats
for
14­
days
prior
to
mating
and
to
pregnant
females
for
an
additional
3
weeks.
The
maximum
dietary
dose
tested
for
both
compounds
was
2,000
mg/
kg
body
weight/
day.
There
were
no
reported
effects
of
treatment
with
either
alcohol
on
the
reproductive
and
developmental
parameters
measured.
4.
Subchronic
toxicity.
Cis­
3­
Hexen­
1­
ol
has
been
evaluated
for
subchronic
toxicity
in
a
98­
day
drinking
water
study
in
rats.
In
this
study,
groups
of
15
male
and
15
female
weanling
SPFderived
CFE
rats,
housed
5
to
a
cage,
were
allowed
to
consume
ad
libitum
drinking
water
containing
either
0,
310,
1,250,
or
5,000
ppm
cis­
3­
hexen­
1­
ol.
Due
to
volatilization
loss,
fresh
solutions
were
prepared
every
2
days.
Body
weights,
and
food
and
water
consumption
were
measured
weekly.
During
the
sixth
week
of
study,
blood
was
collected
from
the
tail
vein
of
eight
rats
of
each
sex
from
the
control,
1,250,
and
5,000
ppm
dose
groups.
At
study
termination,
blood
was
collected
from
the
aorta
of
all
animals.
Hematological
parameters
measured
included:
hemoglobin
concentration,
hematocrit
value,
erythrocyte
and
reticulocyte
counts,
and
total
and
differential
leukocyte
counts.
At
study
termination,
serum
was
analyzed
for
the
concentration
of
urea
and
for
the
activities
of
glutamic­
oxalacetic
and
glutamic­
pyruvic
transaminases.
Urine
was
collected
from
eight
rats
of
each
sex
from
each
dose
group
during
the
sixth
week
of
study.
Urine
samples
were
also
collected
from
12
rats
of
each
group
during
the
last
week
of
study.
Urine
was
analyzed
for
pH,
presence
of
microscopic
constituents,
and
for
bile,
blood,
and
glucose
content.
Kidney
function
was
further
evaluated
through
measurement
of
the
volume
and
specific
gravity
of
urine
produced
during:
(
i)
A
6­
hour
period
of
water
deprivation,
(
ii)
the
first
2
hours
after
loading
with
a
water
dose
of
25
milliliter
(
ml)/
kg
body
weight,
and
(
iii)
a
4­
hour
period
starting
16
hours
after
water
loading.
Following
termination
with
barbiturate,
all
rats
were
necropsied,
and
all
major
tissues
grossly
observed.
The
brain,
pituitary
gland,
thyroid
gland,
heart,
liver,
spleen,
kidneys,
adrenals,
and
gonads
were
weighed.
Tissues
from
the
high­
dose
and
control
rats
were
subject
to
histopathological
examination.
Treatment
with
cis­
3­
hexen­
1­
ol
had
no
effect
on
mortality,
clinical
signs,
body
weight
gains,
or
on
food
consumption.
In
males
treated
at
5,000
ppm
there
was
tendency
to
decreased
water
consumption,
likely
as
a
result
of
the
reduced
palatability
of
the
solution.
In
addition,
in
the
high­
dose
males,
relative
kidney
weights
were
increased
and
the
urine
collected
during
the
first
2
hours
following
water
loading
more
concentrated
(
i.
e.,
had
a
higher
specific
gravity)
in
comparison
to
the
controls.
In
high­
dose
females,
transitory
anemia
was
observed
with
reduced
hemoglobin
concentration
during
week
6
of
the
study.
The
no
observed
adverse
effect
level
(
NOAEL)
was
considered
by
the
study
authors
to
be
1,250
ppm
in
the
drinking
water.
This
concentration
was
stated
to
equate
to
a
cis­
3­
hexen­
1­
ol
intake
of
approximately
120
to
150
mg/
kg
body
weight/
day.
5.
Chronic
toxicity.
Cis­
3­
Hexen­
1­
ol
has
not
been
tested
in
a
chronic
toxicity
or
in
an
oncogenicity
study
in
rodents.
Based
on
a
lack
of
structural
alerts
for
genotoxicity,
and
given
its
biotransformation
to
endogenous
substrates
that
participate
in
fatty
acid
metabolism
in
conjunction
with
the
lack
of
target
organ
toxicity
or
of
effects
potentially
considered
preneoplastic
(
e.
g.,
hyperplasia)
in
the
98­
day
drinking
water
study,
cis­
3­
hexen­
1­
ol
is
not
expected
to
possess
carcinogenic
properties.
In
addition,
cis­
3­
hexen­
1­
ol
is
a
linear
unsaturated
alcohol
unrelated
to
the
branched
chain
saturated
alcohol,
2­
ethylhexanol,
for
which
there
exists
some
evidence
of
hepatotoxic
and
neoplastic
potential
in
rodents
as
a
result
of
the
cascade
of
events
associated
with
the
induction
of
peroxisome
proliferation.
6.
Animal
metabolism.
The
metabolism
of
cis­
3­
hexen­
1­
ol
in
mammalian
systems
has
not
been
specifically
investigated.
One
study
on
the
saturated
homologue
of
cis­
3­
hexen­
1­
ol,
n­
hexanol,
demonstrated
that
following
an
oral
dose
of
8
millimol
(
mmol)/
kg
body
weight
(
816
mg/
kg
body
weight)
to
rabbits,
the
main
metabolites
(
90%)
were
those
associated
with
oxidation
to
the
corresponding
aldehyde
and
acid,
with
further
a
 
­
oxidation
to
carbon
dioxide
and
water.
Direct
conjugation
of
n­
hexanol
with
glucuronide
was
reportedly
a
minor
(
10%)
metabolic
pathway.
Primary
aliphatic
alcohols
attached
to
either
linear,
branched,
or
unsaturated
alky
chains
(
i.
e.,
as
is
the
case
with
cis­
3­
hexen­
1­
ol)
are
efficiently
oxidized
to
the
corresponding
aldehyde
by
NAD+/
NADH­
dependent
alcohol
dehydrogenase
and
then
to
the
carboxylic
acid
by
aldehyde
dehydrogenase.
As
a
result,
cis­
3­
hexen­
1­
ol
would
be
expected
to
be
efficiently
oxidized
to
the
corresponding
aldehyde
and
acid.
The
unsaturated
carboxylic
acids
that
result
from
the
oxidative
metabolism
of
linear
unsaturated
primary
alcohols
(
e.
g.,
cis­
3­
hexen­
1­
ol)
are
known
to
participate
in
normal
fatty
acid
metabolism.
7.
Metabolite
toxicology.
The
metabolism
of
cis­
3­
hexen­
1­
ol
has
not
been
studied
in
mammalian
species.
Potential
metabolites
include
3­
hexanal,
hexenoic
acid,
hexanoic
acid
and
lower
homologues
produced
through
a
 
­
oxidation.
The
Joint
Expert
Committee
on
Food
Additives
has
determined
that
at
expected
per
capita
intakes
in
the
Unites
States,
that
cis­
3­
hexenal
and
cis­
3­
hexenoic
acid
pose
no
safety
concern.
Dietary
intakes
were
based
on
the
use
of
the
substances
as
flavoring
agents.
8.
Endocrine
disruption.
In
the
98­
day
drinking
water
study
on
cis­
3­
hexen­
1­
ol
in
rats,
there
were
no
effects
on
endocrine
or
reproductive
tissues.
There
was
no
evidence
of
any
toxic
effect
that
could
be
interpreted
to
indicated
hormone­
disrupting
activity.

C.
Aggregate
Exposure
1.
Dietary
exposure.
Chronic
dietary
exposure
to
cis­
3­
hexen­
1­
ol
has
occurred
for
centuries
due
its
natural
presence
in
many
foodstuffs
and
due
to
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136
/
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16,
2003
/
Notices
the
use
of
this
substance
as
a
flavoring
agent.
With
respect
to
the
natural
presence
of
cis­
3­
hexen­
1­
ol
in
food,
common
sources
include:
All
green
leafy
plants,
cruciferous
plants,
many
fruits
and
vegetable,
particularly
tomatoes,
and
many
essential
oils.
More
than
10,000
kg
of
cis­
3­
hexen­
1­
ol
may
be
consumed
in
the
United
Sates
from
its
natural
presence
in
tomatoes
alone.
Cis­
3­
Hexen­
1­
ol
is
consumed
primarily
through
its
use
as
a
flavoring
agent.
Based
on
measured
concentrations
in
foods
and
the
use
of
consumption
estimates
of
various
food
categories,
per
capita
consumption
cis­
3­
hexen­
1­
ol
is
estimated
at
about
1
mg/
kg
body
weight/
day.
About
0.018
mg/
kg
body
weight
per
day
may
be
consumed
as
a
result
of
the
use
of
cis­
3­
hexen­
1­
ol
as
a
flavoring
agent.
The
residues
of
cis­
3­
hexen­
1­
ol
on
raw
agricultural
commodities,
due
to
application
in
paraquat
formulations
only,
are
expected
to
be
negligible,
particularly
in
contrast
to
the
human
exposures
to
cis­
3­
hexen­
1­
ol
from
its
natural
presence
foods
and
from
its
use
as
a
flavoring
agent.
Based
on
the
expected
relative
concentrations
of
cis­
3­
hexen­
1­
ol
in
paraquat
formulations
and
on
the
chronic
dietary
intake
of
paraquat
calculated
in
the
RED
document
(
U.
S.
EPA,
1997)
for
paraquat
dichloride,
chronic
exposures
to
residues
of
cis­
3­
hexen­
1­
ol
of
0.0000076
and
0.000024
mg/
kg
body
weight/
day,
respectively,
were
calculated
for
the
U.
S.
population
and
for
non­
nursing
infants
less
than
1­
year
old.
These
calculated
chronic
exposures
to
cis­
3­
hexen­
1­
ol
residues
on
food
are
more
than
40,000­
fold
lower
than
exposures
occurring
from
the
natural
presence
of
cis­
3­
hexen­
1­
ol
in
foods
(
i.
e.,
1
mg/
kg
body
weight/
day
from
natural
occurrence
in
food
/
0.000024
mg/
kg
body
weight/
day
from
possible
residues
on
paraquat­
treated
food
products).
i.
Food.
Chronic
dietary
exposure
to
cis­
3­
hexen­
1­
ol
has
occurred
for
centuries
due
its
natural
presence
in
many
foodstuffs
and
due
to
the
use
of
this
substance
as
a
flavoring
agent.
With
respect
to
the
natural
presence
of
cis­
3­
hexen­
1­
ol
in
food,
common
sources
include:
all
green
leafy
plants,
cruciferous
plants,
many
fruits
and
vegetable,
particularly
tomatoes,
and
many
essential
oils.
More
than
10,000
kg
of
cis­
3­
hexen­
1­
ol
may
be
consumed
in
the
United
Sates
from
its
natural
presence
in
tomatoes
alone.
Cis­
3­
Hexen­
1­
ol
is
consumed
primarily
through
its
use
as
a
flavoring
agent.
Based
on
measured
concentrations
in
foods
and
the
use
of
consumption
estimates
of
various
food
categories,
per
capita
consumption
cis­
3­
hexen­
1­
ol
is
estimated
at
about
1
mg/
kg
body
weight/
day.
About
0.018
mg/
kg
body
weight
per
day
may
be
consumed
as
a
result
of
the
use
of
cis­
3­
hexen­
1­
ol
as
a
flavoring
agent.
The
residues
of
cis­
3­
hexen­
1­
ol
on
raw
agricultural
commodities,
due
to
application
in
paraquat
formulations,
are
expected
to
be
negligible,
particularly
in
contrast
to
the
human
exposures
to
cis­
3­
hexen­
1­
ol
from
its
natural
presence
foods
and
from
its
use
as
a
flavoring
agent.
ii.
Drinking
water.
Exposures
to
cis­
3­
hexen­
1­
ol
from
drinking
water
are
expected
to
be
negligible.
Given
the
volatile
nature
of
cis­
3­
hexen­
1­
ol,
any
trace
concentrations
of
cis­
3­
hexen­
1­
ol
that
may
enter
drinking
water
supplies
would
be
readily
off­
gassed.
In
any
case,
given
its
toxicological
profile,
cis­
3­
hexen­
1­
ol
could
not
be
present
in
drinking
water
at
concentrations
of
concern
for
human
health.
2.
Non­
dietary
exposure.
Cis­
3­
Hexen­
1­
ol,
and
a
number
of
related
alcohols
and
aldehydes,
is
a
common
constituent
of
the
leafy
portions
of
many
plant
species,
hence
the
name
``
leaf
alcohol
''.
A
number
of
studies
have
reported
the
presence
of
cis­
3­
hexen­
1­
ol
and
other
compounds
in
the
off­
gas
emissions
from
agricultural
and
non­
agricultural
(
forest)
plant
species.
While
emissions
from
these
sources
appear
considerable,
it
is
not
possible
to
determine
the
extent
of
inhalation
exposure
to
cis­
3­
hexen­
1­
ol
from
these
sources.

D.
Cumulative
Effects
Cis­
3­
Hexen­
1­
ol
has
been
shown
in
a
98­
day
toxicity
study
not
to
produce
overt
organ
toxicity.
In
addition,
biochemical
and
metabolic
considerations
indicate
that
cis­
3­
hexen­
1­
ol
would
be
metabolized
to
the
corresponding
aldehydes
and
acids,
which,
in
turn,
would
be
normal
substrates
for
enzymes
involved
in
fatty
acid
catabolism.
Based
on
these
data,
there
would
appear
to
be
no
evidence
for
a
``
common
mechanism
''
of
toxicity
with
other
substances.
Simple
metabolism
along
a
common
metabolic
pathway
does
not
constitute
a
``
common
mechanism
of
toxicity''.
As
a
result,
there
is
no
expectation
that
the
use
of
cis­
3­
hexen­
1­
ol
as
an
inert
ingredient
in
paraquat
dichloride
pesticide
formulations
(
at
up
to
4
grams/
L)
would
contribute
to
any
cumulative
toxicity
arising
from
exposure
to
other
substances
having
a
common
mechanism
of
toxicity.

E.
Safety
Determination
1.
U.
S.
population.
The
results
of
the
acute
toxicity
studies,
irritation
and
sensitization
studies,
and
the
98­
day
subchronic
toxicity
study
demonstrate
that
cis­
3­
hexen­
1­
ol
is
of
a
low
order
of
toxicity,
with
no
overt
organ
toxicity,
even
at
high
dosages.
Cis­
3­
Hexen­
1­
ol
is
not
anticipated
to
be
genotoxic,
a
conclusion
consistent
with
the
results
reported
for
similar
compounds.
Similarly,
metabolic
considerations
provide
no
evidence
of
severe
toxicity
since
cis­
3­
hexen­
1­
ol
is
likely
biotransformed
to
the
corresponding
unsaturated
carboxylic
acid,
a
compound
that
would
participate
in
normal
fatty
acid
metabolism.
Use
of
cis­
3­
hexen­
1­
ol
at
up
to
4
grams/
L
in
paraquat
dichloride
pesticide
formulations
is
not
expected
to
produce
significant
residues
in
raw
agricultural
commodities.
Based
on
tolerances
established
for
paraquat
and
on
the
anticipated
relative
concentrations
of
paraquat
and
cis­
3­
hexen­
1­
ol
in
end
use
formulations,
maximum
residues
of
cis­
3­
hexen­
1­
ol
were
estimated
to
be
in
the
range
of
0.0009
ppm.
Under
field
conditions,
the
residues
of
cis­
3­
hexen­
1­
ol
are
expected
to
be
even
lower
since
cis­
3­
hexen­
1­
ol
is
highly
volatile
with
a
much
higher
vapor
pressure
than
paraquat
dichloride.
At
these
maximum
residue
levels,
the
maximum
chronic
exposures
to
cis­
3­
hexen­
1­
ol
were
estimated
to
be
0.0000076
and
0.000024
mg/
kg
body
weight/
day,
respectively,
for
the
U.
S.
population
and
for
nonnursing
infants
less
than
1­
year
old.
These
calculated
chronic
exposures
to
cis­
3­
hexen­
1­
ol
residues
on
food
are
more
than
40,000­
fold
lower
than
exposures
occurring
from
the
natural
presence
of
cis­
3­
hexen­
1­
ol
in
foods.
Based
on
the
preceding
analysis,
Syngenta
Crop
Protection,
Inc.,
believes
that
there
is
a
reasonable
certainty
that
no
harm
will
result
to
the
general
population,
including
subgroups
such
as
infants
and
children,
from
aggregate
exposures
to
cis­
3­
hexen­
1­
ol.
2.
Infants
and
children.
Based
on
the
data
presented
in
the
preceding
sections
and
on
the
safety
analysis
presented
above,
Syngenta
Crop
Protection,
Inc.,
believes
that
there
is
a
reasonable
certainty
that
no
harm
will
result
to
infants
and
children
from
aggregate
exposures
to
cis­
3­
hexen­
1­
ol.

F.
International
Tolerances
No
tolerances,
or
exemptions
for
tolerance,
for
cis­
3­
hexenol
have
been
previously
requested
by
Syngenta
Crop
Protection,
Inc.
A
maximum
residue
level
(
MRL)
for
cis­
3­
hexen­
1­
ol
has
not
been
established
by
the
Codex
Alimentarus
Commission.
In
the
United
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/
Vol.
68,
No.
136
/
Wednesday,
July
16,
2003
/
Notices
States,
cis­
3­
hexen­
1­
ol
is
cleared
for
use
in
non­
food
pesticide
applications.
[
FR
Doc.
03
 
17899
Filed
7
 
15
 
03;
8:
45
am]

BILLING
CODE
6560
 
50
 
S
ENVIRONMENTAL
PROTECTION
AGENCY
[
RCRA
 
2003
 
0013;
SWH
 
FRL
 
7527
 
9]

Recovered
Materials
Advisory
Notice
AGENCY:
Environmental
Protection
Agency.
ACTION:
Notice
of
data
availability.

SUMMARY:
On
August
28,
2001,
the
U.
S.
Environmental
Protection
Agency
(
EPA
or
the
Agency)
proposed
to
designate
nylon
carpet
in
its
Comprehensive
Procurement
Guideline
IV
(
CPG
IV).
On
that
same
day,
EPA
issued
a
Draft
Recovered
Materials
Advisory
Notice
IV
(
RMAN
IV)
for
nylon
carpet.
The
RMAN
provides
guidance
to
procuring
agencies
for
purchasing
items
designated
in
the
CPG.
Specifically,
Table
C
 
4
of
the
draft
RMAN
IV
contained
recommended
recovered
materials
content
ranges
for
use
by
procurement
officials
when
buying
nylon
carpet
containing
recovered
materials
and/
or
nylon
carpet
with
backing
made
from
recovered
materials.
Today's
action
announces
the
availability
of
information
submitted
both
during
and
after
the
close
of
the
public
comment
period
for
the
draft
RMAN
IV
for
nylon
carpet,
provides
a
summary
of
the
revisions
EPA
is
considering
making
to
the
draft
RMAN
for
nylon
carpet
as
a
result
of
comments
received,
and
requests
comments
both
on
the
information
submitted
and
on
the
revisions
being
considered
for
the
RMAN
on
nylon
carpet.
EPA
will
consider
information
and
data
submitted
in
response
to
this
notice
when
issuing
the
final
RMAN
recommendations
for
nylon
carpet.
EPA
notes
that
in
the
August
28,
2001
rulemaking
notice,
10
other
items
were
proposed
for
designation
in
the
CPG.
The
agency
is
currently
reviewing
comments
received
on
those
proposed
designations
and
will
be
issuing
a
separate
rulemaking
notice
for
those
items
in
the
near
future.
DATES:
EPA
will
accept
public
comments
on
this
Notice
of
Data
Availability
until
September
2,
2003.
ADDRESSES:
Comments
may
be
submitted
electronically,
by
mail,
or
through
hand
delivery/
courier.
Follow
the
detailed
instructions
as
provided
in
Unit
I.
B
of
the
SUPPLEMENTARY
INFORMATION
section.
FOR
FURTHER
INFORMATION
CONTACT:
For
general
information
contact
the
RCRA
Call
Center
at
(
800)
424
 
9346
or
TDD
(
800)
553
 
7672
(
hearing
impaired).
In
the
Washington,
DC
metropolitan
area,
call
(
703)
412
 
9810
or
TDD
(
703)
412
 
3323.
For
technical
information
pertaining
to
this
notice,
contact
Sue
Nogas
at
(
703)
308
 
0199.
SUPPLEMENTARY
INFORMATION:

I.
General
Information
A.
How
Can
I
Get
Copies
of
This
Document
and
Other
Related
Information?
1.
Docket.
EPA
has
established
an
official
public
docket
for
the
materials
discussed
in
this
notice
under
Docket
ID
No.
RCRA
 
2003
 
0013.
The
official
public
docket
consists
of
the
documents
specifically
referenced
in
this
action,
any
public
comments
received,
and
other
information
related
to
this
action.
Although
a
part
of
the
official
docket,
the
public
docket
does
not
include
Confidential
Business
Information
(
CBI)
or
other
information
whose
disclosure
is
restricted
by
statute.
The
official
public
docket
is
the
collection
of
materials
that
is
available
for
public
viewing
at
the
RCRA
Docket
in
the
EPA
Docket
Center,
(
EPA/
DC)
EPA
West,
Room
B102,
1301
Constitution
Ave.,
NW.,
Washington,
DC.
The
EPA
Docket
Center
Public
Reading
Room
is
open
from
8:
30
a.
m.
to
4:
30
p.
m.,
Monday
through
Friday,
excluding
legal
holidays.
The
telephone
number
for
the
Public
Reading
Room
is
(
202)
566
 
1744,
and
the
telephone
number
for
the
RCRA
Docket
is
(
202)
566
 
0270.
Copies
cost
$.
15
per
page.
2.
Electronic
Access.
You
may
access
this
Federal
Register
document
electronically
through
the
EPA
Internet
under
the
``
Federal
Register''
listings
at
http://
www.
epa.
gov/
fedrgstr/.
An
electronic
version
of
the
public
docket
is
available
through
EPA's
electronic
public
docket
and
comment
system,
EPA
Dockets.
You
may
use
EPA
Dockets
at
http://
www.
epa.
gov/
edocket/
to
submit
or
view
public
comments,
access
the
index
listing
of
the
contents
of
the
official
public
docket,
and
to
access
those
documents
in
the
public
docket
that
are
available
electronically.
Once
in
the
system,
select
``
search,''
then
key
in
the
appropriate
docket
identification
number.
Certain
types
of
information
will
not
be
placed
in
the
EPA
Dockets.
Information
claimed
as
CBI
and
other
information
whose
disclosure
is
restricted
by
statute,
which
is
not
included
in
the
official
public
docket,
will
not
be
available
for
public
viewing
in
EPA's
electronic
public
docket.
EPA's
policy
is
that
copyrighted
material
will
not
be
placed
in
EPA's
electronic
public
docket
but
will
be
available
only
in
printed,
paper
form
in
the
official
public
docket.
To
the
extent
feasible,
publicly
available
docket
materials
will
be
made
available
in
EPA's
electronic
public
docket.
When
a
document
is
selected
from
the
index
list
in
EPA
Dockets,
the
system
will
identify
whether
the
document
is
available
for
viewing
in
EPA's
electronic
public
docket.
Although
not
all
docket
materials
may
be
available
electronically,
you
may
still
access
any
of
the
publicly
available
docket
materials
through
the
docket
facility
identified
in
Unit
I.
A.
For
public
commenters,
it
is
important
to
note
that
EPA's
policy
is
that
public
comments,
whether
submitted
electronically
or
in
paper,
will
be
made
available
for
public
viewing
in
EPA's
electronic
public
docket
as
EPA
receives
them
and
without
change,
unless
the
comment
contains
copyrighted
material,
CBI,
or
other
information
whose
disclosure
is
restricted
by
statute.
When
EPA
identifies
a
comment
containing
copyrighted
material,
EPA
will
provide
a
reference
to
that
material
in
the
version
of
the
comment
that
is
placed
in
EPA's
electronic
public
docket.
The
entire
printed
comment,
including
the
copyrighted
material,
will
be
available
in
the
public
docket.
Public
comments
submitted
on
computer
disks
that
are
mailed
or
delivered
to
the
docket
will
be
transferred
to
EPA's
electronic
public
docket.
Public
comments
that
are
mailed
or
delivered
to
the
Docket
will
be
scanned
and
placed
in
EPA's
electronic
public
docket.
Where
practical,
physical
objects
will
be
photographed,
and
the
photograph
will
be
placed
in
EPA's
electronic
public
docket
along
with
a
brief
description
written
by
the
docket
staff.

B.
How
and
To
Whom
Do
I
Submit
Comments?
You
may
submit
comments
electronically,
by
mail,
or
through
hand
delivery/
courier.
To
ensure
proper
receipt
by
EPA,
identify
the
appropriate
docket
identification
number
in
the
subject
line
on
the
first
page
of
your
comment.
Please
ensure
that
your
comments
are
submitted
within
the
specified
comment
period.
Comments
received
after
the
close
of
the
comment
period
will
be
marked
``
late.''
EPA
will
consider
late
comments
if
time
permits.
1.
Electronically.
If
you
submit
an
electronic
comment
as
prescribed
below,
EPA
recommends
that
you
include
your
name,
mailing
address,
and
an
e­
mail
address
or
other
contact
information
in
the
body
of
your
comment.
This
ensures
that
you
can
be
identified
as
the
submitter
of
the
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