       MMT[(R)]/Mn Alternative Tier 2 Health Testing Program (Stage 1): 
        Concluding Meeting of the Mn PBPK Technical Advisory Panel  - 
                Presentation and Discussion of Overall Results
                                       
                     Hamner Institutes for Health Science
                          Thursday, January 29, 2008

Agenda

9:00  -  9:10 AM		Introduction (Andersen)

9:10  -  9:30			Alternative Tier 2 (Stage 1)  -  A Successful
				Collaboration among Government, Research
				Organizations, Universities and Industry (Roper) 

9:30  -  10:30			Developing Multi-Dose Route, Multi-Species PBPK Models for
				Mn over Various Life Stages
                        (1) Conceptualization and development of the models (Andersen)
                        (2) Mn PBPK model for the adult rat and monkey (Nong)


10:30  -  10:45			Break

10:45  -  11:30			(3) Mn PBPK model describing gestation and lactation in the rat
				      (Yoon)

11:30  -  Noon 			Q&A

Noon  -  1:00 PM		Lunch  -  Sandwiches, salad, beverage; cost $5.
				Posters and reprints will be on exhibit


1:00  -  2:00			Pharmacokinetic Modeling and Mn Risk Assessment (Clewell)

2:00  -  2:30 			Q&A

2:30  -  2:45			Break

2:45  -  3:15			TAP views, overall discussion and wrap-up

                  	
                  	
                  	

